Reactive rifampicin derivative able to damage transcription complex

Bioconjugate Chemistry

Volumn 24, Issue 3, 2013, Pages 443-447

  Kozlov, Maxim ^a,b   Nudler, Eugeny ^a,d   Nikiforov, Vadim ^a,c   Mustaev, Arkady ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^c INSTITUTE OF MOLECULAR GENETICS   (Russian Federation)

^d NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; DEGRADATION; DRUG PRODUCTS; RNA; TRANSCRIPTION;

ACTIVE CHEMICALS; BINDING AFFINITIES; BLOCKINGS; BROAD SPECTRUM ANTIBIOTICS; CHEMICAL GROUP; COLLATERAL DAMAGE; DEGRADATION PRODUCTS; LOCALISED; PERFORMANCE; RNA POLYMERASE;

BINDING SITES;

BACTERIAL RNA; MEDIATOR COMPLEX; RIFAMYCIN B; RNA POLYMERASE; RNA POLYMERASE BETA SUBUNIT;

ARTICLE; BINDING AFFINITY; DRUG BINDING; DRUG BINDING SITE; DRUG DEGRADATION; DRUG HYDROLYSIS; DRUG SYNTHESIS; TRANSCRIPTION INITIATION SITE;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM;

EID: 84875418067     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc3005667     Document Type: Article

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