A novel mechanism of NALP3 inducing ischemia reperfusion injury by activating MAPK pathway in acute renal failure

Medical Hypotheses

Volumn 80, Issue 4, 2013, Pages 463-465

  Hao, J L ^a   Li, Y F ^a   Li, R S ^a  

^a SHANXI MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; INFLAMMASOME; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE;

ACUTE KIDNEY FAILURE; APOPTOSIS; ARTICLE; COMPLEX FORMATION; ENZYME ACTIVATION; HUMAN; INFLAMMATION; KIDNEY ISCHEMIA; MOLECULAR MECHANICS; PROTEIN DOMAIN; PROTEIN STRUCTURE; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

ACUTE KIDNEY INJURY; CARRIER PROTEINS; HUMANS; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; REPERFUSION INJURY;

EID: 84875403377     PISSN: 03069877     EISSN: 15322777     Source Type: Journal    
DOI: 10.1016/j.mehy.2012.12.041     Document Type: Article

References (22)

1. Lameire N., Van Biesen W., Vanholder R. Acute renal failure. Lancet 2005, 365:417-430.
2. Joly Sophie, Ma Ning, Sadler Jeffrey J., Soll David R., Cassel Suzanne L., Sutterwala Fayyaz S. Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome. Immunology 2009, 183:3578-3581.
3. Li Hanfen., Ambade Aditya., Re Fabio. Necrosis activates the NLRP3 inflammasom. Immunology 2009, 183:1528-1532.
4. Martinon F., Tschopp J. NLRs join TLRs as innate sensors of pathogens. Trends Immunol 2005, 26:447-454.
5. Terman A., Kurz T., Gustafsson B., Brunk U.T. Lysosomal labilization. IUBMB Life 2006, 58:531-539.
6. Fritz J.H., Ferrero R.L., Philpott D.J., Girardin S.E. Nod-like proteins in immunity, inflammation and disease. Nat Immunol 2006, 7:1250-1257.
7. Mariathasan S., Weiss D.S., Newton K., et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 2006, 440:228-232.
8. Thompson Mikayla R., Kaminski John J., Kurt-Jones Evelyn A., Fitzgerald Katherine A. Pattern Recognition Receptors and the Innate Immune Response to Viral Infection. Viruses 2011, 3:920-940.
9. Turner M.D., Chaudhry A., Nedjai B. Tumour necrosis factor receptor trafficking dysfunction opens the TRAPS door to pro-inflammatory cytokine secretion. Bioscience 2011, 32:105-112.
10. Whitmarsh A.J., Davis R.J. Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways. Mol Med 1996, 74:589-607.
11. Robinson M.J., Cobb M.H. Mitogen-activated protein kinase pathways. Cell Biol 1997, 9:180-186.
12. Ip Y.T., Davis R.J. Signal transduction by the c-Jun N-terminal kinase (JNK): from inflammation to development. Cell Biol 1998, 10:205-219.
13. Ichijo H., Nishida E., Irie K., et al. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 1997, 275:90-94.
14. Tobiume K., Matsuzawa A., Takahashi T., et al. ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis. EMBO 2001, 2:222-228.
15. Johnson G.L., Lapadat R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002, 298:1911-1912.
16. Shigeoka Alana A., Mueller James L., Kambo Amanpreet, et al. A novel inflammasome-independent role for epithelial expressed Nlrp3 in renal ischemia-reperfusion injury. Immunology 2010, 185:6277-6285.
17. Yu H.B., Finlay B.B. The caspase-1 inflammasome: a pilot of innate immune responses. Cell Host Microbe 2008, 4:198-208.
18. Church L.D., Cook G.P., McDermott M.F. Primer: inflammasomes and interleukin 1beta in inflammatory disorders. Nat Clin Pract Rheumatol 2008, 4:34-42.
19. Taxman D.J., Holley-Guthrie E.A., Huang M.T., et al. The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and Shamokin induction independent of the inflammasome. Biol Chem 2011, 286:19605-19616.
20. Tao M., Scacheri P.C., Marinis J.M., Harhaj E.W., Matesic L.E., Abbott D.W., et al. ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways. Curr Biol 2009, 19:1255-1263.
21. Lamkanfi Mohamed, Mueller James L., Vitari Alberto C., et al. Glyburide inhibits the Cryopyrin/Nalp3 inflammasome. Cell Biol 2009, 187:61-70.
22. Snoeijs M.G., van Bijnen A., Swennen E., et al. Tubular epithelial injury and inflammation after ischemia and reperfusion in human kidney transplantation. Ann Surg 2011, 253:598-604.