Advances in cell lineage reprogramming

Science China Life Sciences

Volumn 56, Issue 3, 2013, Pages 228-233

  Zhou, JunNian ^a   Yue, Wen ^a   Pei, XueTao ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

dedifferentiation; lineage reprogramming; regenerative medicine; transdetemination; transdifferentiation

Indexed keywords

IPS;

EID: 84875384648     PISSN: 16747305     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11427-013-4447-7     Document Type: Review

References (45)

1. Yamanaka S. Strategies and new developments in the generation of patient-specific pluripotent stem cells. Cell Stem Cell, 2007, 1: 39-49.
2. Zhou Q, Melton D A. Extreme makeover: converting one cell into another. Cell Stem Cell, 2008, 3: 382-388.
3. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell, 2006, 126: 663-676.
4. Davis R L, Weintraub H, Lassar A B. Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell, 1987, 51: 987-1000.
5. Xie H, Ye M, Feng R, et al. Stepwise reprogramming of B cells into macrophages. Cell, 2004, 117: 663-676.
6. Petersen B E, Bowen W C, Patrene K D, et al. Bone marrow as a potential source of hepatic oval cells. Science, 1999, 284: 1168-1170.
7. Graf T, Enver T. Forcing cells to change lineages. Nature, 2009, 62: 587-594.
8. Jiang Y, Jahagirdar B N, Reinhardt R L, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature, 2002, 418: 41-49.
9. Krause D S, Theise N D, Collector M I, et al. Multi-organ, multilineage engraftment by a single bone marrow-derived stem cell. Cell, 2001, 105: 369-377.
10. Feng R, Desbordes S C, Xie H, et al. PU. 1 and C/EBPalpha/beta convert fibroblasts into macrophage-like cells. Proc Natl Acad Sci USA, 2008, 105: 6057-6062.
11. Takeuchi J K, Bruneau B G. Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors. Nature, 2009, 459: 708-711.
12. Ieda M, Fu J D, Delgado-Olguin P, et al. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell, 2010, 142: 375-386.
13. Vierbuchen T, Ostermeier A, Pang Z P, et al. Direct conversion of fibroblasts to functional neurons by defined factors. Nature, 2010, 463: 1035-1041.
14. Pang Z P, Yang N, Vierbuchen T, et al. Induction of human neuronal cells by defined transcription factors. Nature, 2011, 476: 220-223.
15. Pfisterer U, Kirkeby A, Torper O, et al. Direct conversion of human fibroblasts to dopaminergic neurons. Proc Natl Acad Sci USA, 2011, 108: 10343-10348.
16. Lujan E, Chanda S, Ahlenius H, et al. Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells. Proc Natl Acad Sci USA, 2012, 109: 2527-2532.
17. Liu X, Li F, Stubblefield E A, et al. Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells. Cell Res, 2012, 22: 321-332.
18. Huang P, He Z, Ji S, et al. Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors. Nature, 2011, 475: 386-389.
19. Sekiya S, Suzuki A. Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors. Nature, 2011, 475: 390-393.
20. Marro S, Pang Z P, Yang N, et al. Direct lineage conversion of terminally differentiated hepatocytes to functional neurons. Cell Stem Cell, 2011, 9: 374-382.
21. Cobaleda C, Jochum W, Busslinger M. Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors. Nature, 2007, 449: 473-477.
22. Szabo E, Rampalli S, Risueño R M, et al. Direct conversion of human fibroblasts to multilineage blood progenitors. Nature, 2010, 468: 521-526.
23. Yuan J, Nguyen C K, Liu X, et al. Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis. Science, 2012, 335: 1195-1200.
24. Efe J A, Hilcove S, Kim J, et al. Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy. Nat Cell Biol, 2011, 13: 215-222.
25. Kim J, Efe J A, Zhu S, et al. Direct reprogramming of mouse fibroblasts to neural progenitors. Proc Natl Acad Sci USA, 2011, 108: 7838-7843.
26. Thier M, Wörsdörfer P, Lakes Y B, et al. Direct conversion of fibroblasts into stably expandable neural stem cells. Cell Stem Cell, 2012, 10: 473-479.
27. Zabierowski S E, Baubet V, Himes B, et al. Direct reprogramming of melanocytes to neural crest stem-like cells by one defined factor. Stem Cells, 2011, 29: 1752-1762.
28. Jang Y, Collector M I, Baylin S B, et al. Hematopoietic stem cells convert into liver cells within days without fusion. Nature Cell Biol, 2004, 6: 532-539.
29. Wang Y, Nan X, Li Y, et al. Induction of umbilical cord blood-derived β2m-c-Met+ cells into hepatocyte-like cells by coculture with CFSC/HGF cells. Liver Transpl, 2005, 11: 635-643.
30. Hou L, Cao H, Wang D, et al. Induction of umbilical cord blood mesenchymal stem cells into neuron-like cells in vitro. Int J Hematol, 2003, 78: 256-261.
31. Wang X, Willenberg H, Akkari Y, et al. Cell fusion is the principal source of bone marrow derived hepatocytes. Nature, 2003, 422: 897-901.
32. Vassilopoulos G, Wang P, Russell D W. Transplanted bone marrow regenerates liver by cell fusion. Nature, 2003, 422: 901-904.
33. Tanabe Y, Tajima F, Nakamura Y, et al. Analyses to clarify rich fractions in hepatic progenitor cells from human umbilical cord blood and cell fusion. Biochem Biophys Res Commun, 2004, 324: 711-718.
34. Zhao L X, Zhang J, Cao F, et al. Modification of the brain-derived neurotrophic factor gene: a portal to transform mesenchymal stem cells into advantageous engineering cells for neuroregeneration and neuroprotection. Exp Neurol, 2004, 190: 396-406.
35. Yang Y, Li Y, Lv Y, et al. NRSF silencing induces neuronal differentiation of human mesenchymal stem cells. Exp Cell Res, 2008, 314: 2257-2265.
36. Li Y, Zhang R, Qiao H, et al. Generation of insulin-producing cells from PDX-1 gene-modified human mesenchymal stem cells. J Cell Physiol, 2007, 211: 36-44.
37. Li B, Wang S, Liu H, et al. Neuronal restrictive silencing factor silencing induces human amniotic fluid-derived stem cells differentiation into insulin-producing cells. Stem Cells Dev, 2011, 20: 1223-1231.
38. Slack J M. Metaplasia and transdifferentiation: from pure biology to the clinic. Nat Rev Mol Cell Biol, 2007, 8: 369-378.
39. Ouyang G, Wang Z, Fang X, et al. Molecular signaling of the epithelial to mesenchymal transition in generating and maintaining cancer stem cells. Cell Mol Life Sci, 2010, 67: 2605-2618.
40. Thiery J P, Acloque H, Huang R Y, et al. Epithelial-mesenchymal transitions in development and disease. Cell, 2009, 139: 871-890.
41. Abollo-Jiménez F, Jiménez R, Cobaleda C. Physiological cellular reprogramming and cancer. Semin Cancer Biol, 2010, 20: 98-106.
42. Yoo A S, Sun A X, Li L, et al. MicroRNA-mediated conversion of human fibroblasts to neurons. Nature, 2011, 476: 228-231.
43. Li W, Jiang K, Ding S. Concise review: A chemical approach to control cell fate and function. Stem Cells, 2012, 30: 61-68.
44. Vierbuchen T, Wernig M. Direct lineage conversions: unnatural but useful? Nat Biotechnol, 2011, 29: 892-907.
45. Zhou Q, Brown J, Kanarek A, et al. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature, 2008, 455: 627-632.