Activation profile of CXCL8-stimulated neutrophils and aging

Cytokine

Volumn 61, Issue 3, 2013, Pages 716-719

  Dalboni, Thalita Marcato ^a   Abe, Aneli Eiko ^a   de Oliveira, Carine Ervolino ^a   Lara, Vanessa Soares ^a   Campanelli, Ana Paula ^a   Gasparoto, Carlos Teodoro ^a   Gasparoto, Thaís Helena ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Antimicrobial enzymes; CXCL8; Elderly; Neutrophils

Indexed keywords

ELASTASE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MYELOPEROXIDASE;

AGED; AGING; ARTICLE; CELL LEVEL; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOKINE RESPONSE; ENZYME ACTIVITY; ENZYME RELEASE; HUMAN; LEUKOCYTE ACTIVATION; NORMAL HUMAN; PRIORITY JOURNAL;

ADULT; AGED; AGING; HUMANS; INTERLEUKIN-8; MIDDLE AGED; NEUTROPHIL ACTIVATION; NEUTROPHILS; PANCREATIC ELASTASE; PEROXIDASE; YOUNG ADULT;

EID: 84875379639     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2013.01.016     Document Type: Article

References (15)

1. Nathan C. Neutrophils and immunity: challenges and opportunities. Nat Rev Immunol 2006, 6:173-182.
2. Amulic B., Cazalet C., Hayes G.L., Metzler K.D., Zychlinsky A. Neutrophil function: from mechanisms to disease. Annu Rev Immunol 2012, 30:459-489.
3. Mukaida N. Pathophysiological roles of interleukin-8/CXCL8 in pulmonary diseases. Am J Physiol Lung Cell Mol Physiol 2003, 284:L566-577.
4. Das S.T., Rajagopalan L., Guerrero-Plata A., Sai J., Richmond A., Garofalo R.P., et al. Monomeric and dimeric CXCL8 are both essential for in vivo neutrophil recruitment. PLoS One 2010, 5:e11754.
5. Stillie R., Farooq S.M., Gordon J.R., Stadnyk A.W. The functional significance behind expressing two IL-8 receptor types on PMN. J Leukoc Biol 2009, 86:529-543.
6. Gasparoto T.H., Vieira N.A., Porto V.C., Campanelli A.P., Lara V.S. Aging exacerbates damage of systemic and salivary neutrophils from patients presenting Candida-related denture stomatitis. Immunol Aging 2009, 6:3.
7. Wenisch C., Patruta S., Daxböck F., Krause R., Hörl W. Effect of age on human neutrophil function. J Leukoc Biol 2000, 67:40-45.
8. Gasparoto T.H., Vieira N.A., Porto V.C., Campanelli A.P., Lara V.S. Differences between salivary and blood neutrophils from elderly and young denture wearers. J Oral Rehabil 2011, 38:41-51.
9. Wessels I., Jansen J., Rink L., Uciechowski P. Immunosenescence of polymorphonuclear neutrophils. Sci World J 2010, 10:145-160.
10. Mantovani A., Cassatella M.A., Costantini C., Jaillon S. Neutrophils in the activation and regulation of innate and adaptive immunity. Nat Rev Immunol 2011, 11:519-531.
11. Meyer P.W., Hodkinson B., Ally M., Musenge E., Wadee A.A., Fickl H., et al. Circulating cytokine profiles and their relationships with autoantibodies, acute phase reactants, and disease activity in patients with rheumatoid arthritis. Mediat Inflamm 2010, 2010:158514.
12. Deane K.D., O'Donnell C.I., Hueber W., Majka D.S., Lazar A.A., Derber L.A., et al. The number of elevated cytokines and chemokines in preclinical seropositive rheumatoid arthritis predicts time to diagnosis in an age-dependent manner. Arthritis Rheum 2010, 62:3161-3172.
13. Németh T., Mócsai A. The role of neutrophils in autoimmune diseases. Immunol Lett 2012, 143:9-19.
14. Gomez C.R., Nomellini V., Faunce D.E., Kovacs E.J. Innate immunity and aging. Exp Gerontol 2008, 43:718-728.
15. Hajishengallis G. Too old to fight? Aging and its toll on innate immunity. Mol Oral Microbiol 2010, 25:25-37.