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Volumn 37, Issue 4, 2013, Pages 455-462

IgD cross-linking induces gene expression profiling changes and enhances apoptosis in chronic lymphocytic leukemia cells

Author keywords

Antigenic stimulation; Apoptosis; B cell receptor; Cell cycle; CLL; Microarray

Indexed keywords

B LYMPHOCYTE RECEPTOR; IMMUNOGLOBULIN D; IMMUNOGLOBULIN M;

EID: 84875375348     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2012.12.019     Document Type: Article
Times cited : (7)

References (32)
  • 2
    • 0028822481 scopus 로고
    • Chronic lymphocytic leukemia
    • Rozman C., Montserrat E. Chronic lymphocytic leukemia. N Engl J Med 1995, 333:1052-1057.
    • (1995) N Engl J Med , vol.333 , pp. 1052-1057
    • Rozman, C.1    Montserrat, E.2
  • 3
    • 20044372326 scopus 로고    scopus 로고
    • In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells
    • Messmer B.T., Messmer D., Allen S.L., Kolitz J.E., Kudalkar P., Cesar D., et al. In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells. J Clin Invest 2005, 115:755-764.
    • (2005) J Clin Invest , vol.115 , pp. 755-764
    • Messmer, B.T.1    Messmer, D.2    Allen, S.L.3    Kolitz, J.E.4    Kudalkar, P.5    Cesar, D.6
  • 4
    • 0033567968 scopus 로고    scopus 로고
    • Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
    • Damle R.N., Wasil T., Fais F., Ghiotto F., Valetto A., Allen S.L., et al. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood 1999, 94:1840-1847.
    • (1999) Blood , vol.94 , pp. 1840-1847
    • Damle, R.N.1    Wasil, T.2    Fais, F.3    Ghiotto, F.4    Valetto, A.5    Allen, S.L.6
  • 5
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
    • Hamblin T.J., Davis Z., Gardiner A., Oscier D.G., Stevenson F.K. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood 1999, 94:1848-1854.
    • (1999) Blood , vol.94 , pp. 1848-1854
    • Hamblin, T.J.1    Davis, Z.2    Gardiner, A.3    Oscier, D.G.4    Stevenson, F.K.5
  • 6
    • 0035803371 scopus 로고    scopus 로고
    • Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia
    • Rosenwald A., Alizadeh A.A., Widhopf G., Simon R., Davis R.E., Yu X., et al. Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. J Exp Med 2001, 194:1639-1647.
    • (2001) J Exp Med , vol.194 , pp. 1639-1647
    • Rosenwald, A.1    Alizadeh, A.A.2    Widhopf, G.3    Simon, R.4    Davis, R.E.5    Yu, X.6
  • 7
    • 0035803464 scopus 로고    scopus 로고
    • Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells
    • Klein U., Tu Y., Stolovitzky G.A., Mattioli M., Cattoretti G., Husson H., et al. Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells. J Exp Med 2001, 194:1625-1638.
    • (2001) J Exp Med , vol.194 , pp. 1625-1638
    • Klein, U.1    Tu, Y.2    Stolovitzky, G.A.3    Mattioli, M.4    Cattoretti, G.5    Husson, H.6
  • 8
    • 33846108722 scopus 로고    scopus 로고
    • Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: pathogenetic implications and clinical correlations
    • Stamatopoulos K., Belessi C., Moreno C., Boudjograh M., Guida G., Smilevska T., et al. Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: pathogenetic implications and clinical correlations. Blood 2007, 109:259-270.
    • (2007) Blood , vol.109 , pp. 259-270
    • Stamatopoulos, K.1    Belessi, C.2    Moreno, C.3    Boudjograh, M.4    Guida, G.5    Smilevska, T.6
  • 9
    • 0042971643 scopus 로고    scopus 로고
    • B cell chronic lymphocytic leukemia: lessons learned from studies of the B cell antigen receptor
    • Chiorazzi N., Ferrarini M. B cell chronic lymphocytic leukemia: lessons learned from studies of the B cell antigen receptor. Annu Rev Immunol 2003, 21:841-894.
    • (2003) Annu Rev Immunol , vol.21 , pp. 841-894
    • Chiorazzi, N.1    Ferrarini, M.2
  • 10
    • 0029836635 scopus 로고    scopus 로고
    • CD38 expression distinguishes two groups of B-cell chronic lymphocytic leukemias with different responses to anti-IgM antibodies and propensity to apoptosis
    • Zupo S., Isnardi L., Megna M., Massara R., Malavasi F., Dono M., et al. CD38 expression distinguishes two groups of B-cell chronic lymphocytic leukemias with different responses to anti-IgM antibodies and propensity to apoptosis. Blood 1996, 88:1365-1374.
    • (1996) Blood , vol.88 , pp. 1365-1374
    • Zupo, S.1    Isnardi, L.2    Megna, M.3    Massara, R.4    Malavasi, F.5    Dono, M.6
  • 11
    • 0037306842 scopus 로고    scopus 로고
    • Differential signaling via surface IgM is associated with VH gene mutational status and CD38 expression in chronic lymphocytic leukemia
    • Lanham S., Hamblin T., Oscier D., Ibbotson R., Stevenson F., Packham G. Differential signaling via surface IgM is associated with VH gene mutational status and CD38 expression in chronic lymphocytic leukemia. Blood 2003, 101:1087-1093.
    • (2003) Blood , vol.101 , pp. 1087-1093
    • Lanham, S.1    Hamblin, T.2    Oscier, D.3    Ibbotson, R.4    Stevenson, F.5    Packham, G.6
  • 12
    • 23844466900 scopus 로고    scopus 로고
    • B-cell receptor translocation to lipid rafts and associated signaling differ between prognostically important subgroups of chronic lymphocytic leukemia
    • Allsup D.J., Kamiguti A.S., Lin K., Sherrington P.D., Matrai Z., Slupsky J.R., et al. B-cell receptor translocation to lipid rafts and associated signaling differ between prognostically important subgroups of chronic lymphocytic leukemia. Cancer Res 2005, 65:7328-7337.
    • (2005) Cancer Res , vol.65 , pp. 7328-7337
    • Allsup, D.J.1    Kamiguti, A.S.2    Lin, K.3    Sherrington, P.D.4    Matrai, Z.5    Slupsky, J.R.6
  • 13
    • 50949128066 scopus 로고    scopus 로고
    • BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgV H unmutated chronic lymphocytic leukemia (CLL) cells
    • Guarini A., Chiaretti S., Tavolaro S., Maggio R., Peragine N., Citarella F., et al. BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgV H unmutated chronic lymphocytic leukemia (CLL) cells. Blood 2008, 112:782-792.
    • (2008) Blood , vol.112 , pp. 782-792
    • Guarini, A.1    Chiaretti, S.2    Tavolaro, S.3    Maggio, R.4    Peragine, N.5    Citarella, F.6
  • 14
    • 33847412872 scopus 로고    scopus 로고
    • ZAP-70 enhances B-cell-receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells
    • Gobessi S., Laurenti L., Longo P.G., Sica S., Leone G., Efremov D.G. ZAP-70 enhances B-cell-receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells. Blood 2007, 109:2032-2039.
    • (2007) Blood , vol.109 , pp. 2032-2039
    • Gobessi, S.1    Laurenti, L.2    Longo, P.G.3    Sica, S.4    Leone, G.5    Efremov, D.G.6
  • 15
    • 47249152803 scopus 로고    scopus 로고
    • Constitutive activation of distinct BCR-signaling pathways in a subset of CLL patients: a molecular signature of anergy
    • Muzio M., Apollonio B., Scielzo C., Frenquelli M., Vandoni I., Boussiotis V., et al. Constitutive activation of distinct BCR-signaling pathways in a subset of CLL patients: a molecular signature of anergy. Blood 2008, 112:188-195.
    • (2008) Blood , vol.112 , pp. 188-195
    • Muzio, M.1    Apollonio, B.2    Scielzo, C.3    Frenquelli, M.4    Vandoni, I.5    Boussiotis, V.6
  • 16
    • 0034651926 scopus 로고    scopus 로고
    • Apoptosis or plasma cell differentiation of CD38-positive B-chronic lymphocytic leukemia cells induced by cross-linking of surface IgM or IgD
    • Zupo S., Massara R., Dono M., Rossi E., Malavasi F., Cosulich M.E., et al. Apoptosis or plasma cell differentiation of CD38-positive B-chronic lymphocytic leukemia cells induced by cross-linking of surface IgM or IgD. Blood 2000, 95:1199-1206.
    • (2000) Blood , vol.95 , pp. 1199-1206
    • Zupo, S.1    Massara, R.2    Dono, M.3    Rossi, E.4    Malavasi, F.5    Cosulich, M.E.6
  • 17
    • 34248354409 scopus 로고    scopus 로고
    • Reversible anergy of sIgM-mediated signaling in the two subsets of CLL defined by VH-gene mutational status
    • Mockridge C.I., Potter K.N., Wheatley I., Neville L.A., Packham G., Stevenson F.K. Reversible anergy of sIgM-mediated signaling in the two subsets of CLL defined by VH-gene mutational status. Blood 2007, 109:4424-4431.
    • (2007) Blood , vol.109 , pp. 4424-4431
    • Mockridge, C.I.1    Potter, K.N.2    Wheatley, I.3    Neville, L.A.4    Packham, G.5    Stevenson, F.K.6
  • 18
    • 77949357521 scopus 로고    scopus 로고
    • Prognostic relevance of in vitro response to cell stimulation via surface IgD in binet stage a CLL
    • Morabito F., Cutrona G., Gentile M., Fabbi M., Matis S., Colombo M., et al. Prognostic relevance of in vitro response to cell stimulation via surface IgD in binet stage a CLL. Br J Haematol 2010, 149:160-163.
    • (2010) Br J Haematol , vol.149 , pp. 160-163
    • Morabito, F.1    Cutrona, G.2    Gentile, M.3    Fabbi, M.4    Matis, S.5    Colombo, M.6
  • 19
    • 0042744791 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia patients with highly stable and indolent disease show distinctive phenotypic and genotypic features
    • Guarini A., Gaidano G., Mauro F.R., Capello D., Mancini F., De Propris M.S., et al. Chronic lymphocytic leukemia patients with highly stable and indolent disease show distinctive phenotypic and genotypic features. Blood 2003, 102:1035-1041.
    • (2003) Blood , vol.102 , pp. 1035-1041
    • Guarini, A.1    Gaidano, G.2    Mauro, F.R.3    Capello, D.4    Mancini, F.5    De Propris, M.S.6
  • 20
    • 0025951144 scopus 로고
    • P53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia
    • Gaidano G., Ballerini P., Gong J.Z., Inghirami G., Neri A., Newcomb E.W., et al. p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia. Proc Natl Acad Sci USA 1991, 88:5413-5417.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5413-5417
    • Gaidano, G.1    Ballerini, P.2    Gong, J.Z.3    Inghirami, G.4    Neri, A.5    Newcomb, E.W.6
  • 21
    • 0037406968 scopus 로고    scopus 로고
    • ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia
    • Crespo M., Bosch F., Villamor N., Bellosillo B., Colomer D., Rozman M., et al. ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia. N Engl J Med 2003, 348:1764-1775.
    • (2003) N Engl J Med , vol.348 , pp. 1764-1775
    • Crespo, M.1    Bosch, F.2    Villamor, N.3    Bellosillo, B.4    Colomer, D.5    Rozman, M.6
  • 22
    • 24944501362 scopus 로고    scopus 로고
    • The prognostic value of CD38 expression in chronic lymphocytic leukaemia patients studied prospectively at diagnosis: a single institute experience
    • Gentile M., Mauro F.R., Calabrese E., De Propris M.S., Giammartini E., Mancini F., et al. The prognostic value of CD38 expression in chronic lymphocytic leukaemia patients studied prospectively at diagnosis: a single institute experience. Br J Haematol 2005, 130:549-557.
    • (2005) Br J Haematol , vol.130 , pp. 549-557
    • Gentile, M.1    Mauro, F.R.2    Calabrese, E.3    De Propris, M.S.4    Giammartini, E.5    Mancini, F.6
  • 23
    • 78751549662 scopus 로고    scopus 로고
    • The lymph node microenvironment promotes B-cell receptor signaling, NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia
    • Herishanu Y., Pérez-Galán P., Liu D., Biancotto A., Pittaluga S., Vire B., et al. The lymph node microenvironment promotes B-cell receptor signaling, NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia. Blood 2011, 117:563-574.
    • (2011) Blood , vol.117 , pp. 563-574
    • Herishanu, Y.1    Pérez-Galán, P.2    Liu, D.3    Biancotto, A.4    Pittaluga, S.5    Vire, B.6
  • 24
    • 0035793042 scopus 로고    scopus 로고
    • Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection
    • Li C., Wong W.H. Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc Natl Acad Sci USA 2001, 98:31-36.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 31-36
    • Li, C.1    Wong, W.H.2
  • 26
    • 0035021567 scopus 로고    scopus 로고
    • Reduced susceptibility to apoptosis correlates with kinetic quiescence in disease progression of chronic lymphocytic leukaemia
    • Ricciardi M.R., Petrucci M.T., Gregorj C., Ariola C., Lemoli R.M., Fogli M., et al. Reduced susceptibility to apoptosis correlates with kinetic quiescence in disease progression of chronic lymphocytic leukaemia. Br J Haematol 2001, 113:391-399.
    • (2001) Br J Haematol , vol.113 , pp. 391-399
    • Ricciardi, M.R.1    Petrucci, M.T.2    Gregorj, C.3    Ariola, C.4    Lemoli, R.M.5    Fogli, M.6
  • 29
    • 80054844491 scopus 로고    scopus 로고
    • ZAP-70 enhances migration of malignant B lymphocytes towards CCL21 by inducing CCR7 expression via IgM-ERK1/2 activation
    • Calpe E., Codony C., Baptista M.J., Abrisqueta P., Del Carpio C., Purroy N., et al. ZAP-70 enhances migration of malignant B lymphocytes towards CCL21 by inducing CCR7 expression via IgM-ERK1/2 activation. Blood 2011, 118:4401-4410.
    • (2011) Blood , vol.118 , pp. 4401-4410
    • Calpe, E.1    Codony, C.2    Baptista, M.J.3    Abrisqueta, P.4    Del Carpio, C.5    Purroy, N.6
  • 31
    • 84859256604 scopus 로고    scopus 로고
    • Inhibiting B-cell receptor signaling pathways in chronic lymphocytic leukemia
    • Burger J.A. Inhibiting B-cell receptor signaling pathways in chronic lymphocytic leukemia. Curr Hematol Malig Rep 2012, 7:26-33.
    • (2012) Curr Hematol Malig Rep , vol.7 , pp. 26-33
    • Burger, J.A.1
  • 32
    • 78951479819 scopus 로고    scopus 로고
    • A phase 1 study of CAL-101, an isoform-selective inhibitor of phosphatidylinositol 3-kinase P110δ, in combination with rituximab and/or bendamustine in patients with relapsed or refractory B-cell malignancies [abstract]
    • [Abstract 2832]
    • Flinn I.W., Schreeder M.T., Wagner-Johnston N., Boccia R.V., Leonard J.P., Coutre S.E., et al. A phase 1 study of CAL-101, an isoform-selective inhibitor of phosphatidylinositol 3-kinase P110δ, in combination with rituximab and/or bendamustine in patients with relapsed or refractory B-cell malignancies [abstract]. Blood (ASH Annual Meeting Abstracts) 2010, 116:2832. [Abstract 2832].
    • (2010) Blood (ASH Annual Meeting Abstracts) , vol.116 , pp. 2832
    • Flinn, I.W.1    Schreeder, M.T.2    Wagner-Johnston, N.3    Boccia, R.V.4    Leonard, J.P.5    Coutre, S.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.