-
1
-
-
33745571976
-
The immune response in atherosclerosis: A double-edged sword
-
Hansson GK, Libby P. The immune response in atherosclerosis: a double-edged sword. Nat Rev Immunol. 2006;6:508-519.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 508-519
-
-
Hansson, G.K.1
Libby, P.2
-
2
-
-
0037180771
-
Inflammation in atherosclerosis
-
Libby P. Inflammation in atherosclerosis. Nature. 2002;420:868-874.
-
(2002)
Nature
, vol.420
, pp. 868-874
-
-
Libby, P.1
-
3
-
-
37349021003
-
Subendothelial lipoprotein retention as the initiating process in atherosclerosis: Update and therapeutic implications
-
Tabas I, Williams KJ, Borén J. Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications. Circulation. 2007;116:1832-1844.
-
(2007)
Circulation
, vol.116
, pp. 1832-1844
-
-
Tabas, I.1
Williams, K.J.2
Borén, J.3
-
4
-
-
66349096056
-
The role of innate immunity in atherogenesis
-
Hartvigsen K, Chou MY, Hansen LF, Shaw PX, Tsimikas S, Binder CJ, Witztum JL. The role of innate immunity in atherogenesis. J Lipid Res. 2009;50 suppl:S388-S393.
-
(2009)
J Lipid Res
, vol.50 SUPPL.
-
-
Hartvigsen, K.1
Chou, M.Y.2
Hansen, L.F.3
Shaw, P.X.4
Tsimikas, S.5
Binder, C.J.6
Witztum, J.L.7
-
5
-
-
77952308908
-
Inhibition of T cell response to native low-density lipoprotein reduces atherosclerosis
-
Hermansson A, Ketelhuth DF, Strodthoff D, Wurm M, Hansson EM, Nicoletti A, Paulsson-Berne G, Hansson GK. Inhibition of T cell response to native low-density lipoprotein reduces atherosclerosis. J Exp Med. 2010;207:1081-1093.
-
(2010)
J Exp Med
, vol.207
, pp. 1081-1093
-
-
Hermansson, A.1
Ketelhuth, D.F.2
Strodthoff, D.3
Wurm, M.4
Hansson, E.M.5
Nicoletti, A.6
Paulsson-Berne, G.7
Hansson, G.K.8
-
6
-
-
79955535643
-
Macrophages in the pathogenesis of atherosclerosis
-
Moore KJ, Tabas I. Macrophages in the pathogenesis of atherosclerosis. Cell. 2011;145:341-355.
-
(2011)
Cell
, vol.145
, pp. 341-355
-
-
Moore, K.J.1
Tabas, I.2
-
7
-
-
34748914299
-
Evolving functions of endothelial cells in inflammation
-
Pober JS, Sessa WC. Evolving functions of endothelial cells in inflammation. Nat Rev Immunol. 2007;7:803-815.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 803-815
-
-
Pober, J.S.1
Sessa, W.C.2
-
8
-
-
66149102423
-
Mechanisms of endothelial dysfunction, injury, and death
-
Pober JS, Min W, Bradley JR. Mechanisms of endothelial dysfunction, injury, and death. Annu Rev Pathol. 2009;4:71-95.
-
(2009)
Annu Rev Pathol
, vol.4
, pp. 71-95
-
-
Pober, J.S.1
Min, W.2
Bradley, J.R.3
-
9
-
-
0041743148
-
AIP1 mediates TNFalpha-induced ASK1 activation by facilitating dissociation of ASK1 from its inhibitor 14-3-3
-
Zhang R, He X, Liu W, Lu M, Hsieh JT, Min W. AIP1 mediates TNFalpha-induced ASK1 activation by facilitating dissociation of ASK1 from its inhibitor 14-3-3. J Clin Invest. 2003;111:1933-1943.
-
(2003)
J Clin Invest
, vol.111
, pp. 1933-1943
-
-
Zhang, R.1
He, X.2
Liu, W.3
Lu, M.4
Hsieh, J.T.5
Min, W.6
-
10
-
-
7244253045
-
-
AIP1/ DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation
-
Zhang H, Zhang R, Luo Y, D'Alessio A, Pober JS, Min W. AIP1/ DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation. J Biol Chem. 2004;279:44955-44965.
-
(2004)
J Biol Chem
, vol.279
, pp. 44955-44965
-
-
Zhang, H.1
Zhang, R.2
Luo, Y.3
D'alessio, A.4
Pober, J.S.5
Min, W.6
-
11
-
-
34447531013
-
RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation
-
Zhang H, Zhang R, Zhang H, Lin Y, Li J, Pober JS, Min W. RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation. J Biol Chem. 2007;282:14788-14796.
-
(2007)
J Biol Chem
, vol.282
, pp. 14788-14796
-
-
Zhang, H.1
Zhang, R.2
Zhang, H.3
Lin, Y.4
Li, J.5
Pober, J.S.6
Min, W.7
-
12
-
-
57449115615
-
AIP1 functions as an endogenous inhibitor of VEGFR2-mediated signaling and inflammatory angiogenesis in mice
-
Zhang H, He Y, Dai S, Xu Z, Luo Y, Wan T, Luo D, Jones D, Tang S, Chen H, Sessa WC, Min W. AIP1 functions as an endogenous inhibitor of VEGFR2-mediated signaling and inflammatory angiogenesis in mice. J Clin Invest. 2008;118:3904-3916.
-
(2008)
J Clin Invest
, vol.118
, pp. 3904-3916
-
-
Zhang, H.1
He, Y.2
Dai, S.3
Xu, Z.4
Luo, Y.5
Wan, T.6
Luo, D.7
Jones, D.8
Tang, S.9
Chen, H.10
Sessa, W.C.11
Min, W.12
-
13
-
-
77950505908
-
1 functions as Arf6-GAP to negatively regulate TLR4 signaling
-
AIP
-
Wan T, Liu T, Zhang H, Tang S, Min W. AIP1 functions as Arf6-GAP to negatively regulate TLR4 signaling. J Biol Chem. 2010;285:3750-3757.
-
(2010)
J Biol Chem
, vol.285
, pp. 3750-3757
-
-
Wan, T.1
Liu, T.2
Zhang, H.3
Tang, S.4
Min, W.5
-
14
-
-
80051781373
-
Aip1 prevents graft arteriosclerosis by inhibiting ifn-?-dependent smooth muscle cell proliferation and intimal expansion
-
Yu L, Qin L, Zhang H, He Y, Chen H, Pober J, Tellides G, Min W. Aip1 prevents graft arteriosclerosis by inhibiting ifn-?-dependent smooth muscle cell proliferation and intimal expansion. Cir Res. 2011;109:418-427
-
(2011)
Cir Res
, vol.109
, pp. 418-427
-
-
Yu, L.1
Qin, L.2
Zhang, H.3
He, Y.4
Chen, H.5
Pober, J.6
Tellides, G.7
Min, W.8
-
15
-
-
77249104533
-
Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis
-
Xie D, Gore C, Liu J, Pong RC, Mason R, Hao G, Long M, Kabbani W, Yu L, Zhang H, Chen H, Sun X, Boothman DA, Min W, Hsieh JT. Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis. Proc Natl Acad Sci USA. 2010;107:2485-2490.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2485-2490
-
-
Xie, D.1
Gore, C.2
Liu, J.3
Pong, R.C.4
Mason, R.5
Hao, G.6
Long, M.7
Kabbani, W.8
Yu, L.9
Zhang, H.10
Chen, H.11
Sun, X.12
Boothman, D.A.13
Min, W.14
Hsieh, J.T.15
-
16
-
-
84947899513
-
Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm
-
Gretarsdottir S, Baas AF, Thorleifsson G, et al. Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm. Nat Genet. 2010;42:692-697.
-
(2010)
Nat Genet
, vol.42
, pp. 692-697
-
-
Gretarsdottir, S.1
Baas, A.F.2
Thorleifsson, G.3
-
17
-
-
0035718119
-
Mechanism of endothelial dysfunction in apolipoprotein E-deficient mice
-
d'Uscio LV, Baker TA, Mantilla CB, Smith L, Weiler D, Sieck GC, Katusic ZS. Mechanism of endothelial dysfunction in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol. 2001;21:1017-1022.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1017-1022
-
-
D'uscio, L.V.1
Baker, T.A.2
Mantilla, C.B.3
Smith, L.4
Weiler, D.5
Sieck, G.C.6
Katusic, Z.S.7
-
18
-
-
0027242030
-
Hypercholesterolemia increases endothelial superoxide anion production
-
Ohara Y, Peterson TE, Harrison DG. Hypercholesterolemia increases endothelial superoxide anion production. J Clin Invest. 1993;91:2546-2551.
-
(1993)
J Clin Invest
, vol.91
, pp. 2546-2551
-
-
Ohara, Y.1
Peterson, T.E.2
Harrison, D.G.3
-
19
-
-
0031018510
-
Tetrahydrobiopterin restores endothelial function in hypercholesterolemia
-
Stroes E, Kastelein J, Cosentino F, Erkelens W, Wever R, Koomans H, Lüscher T, Rabelink T. Tetrahydrobiopterin restores endothelial function in hypercholesterolemia. J Clin Invest. 1997;99:41-46.
-
(1997)
J Clin Invest
, vol.99
, pp. 41-46
-
-
Stroes, E.1
Kastelein, J.2
Cosentino, F.3
Erkelens, W.4
Wever, R.5
Koomans, H.6
Lüscher, T.7
Rabelink, T.8
-
20
-
-
0027958084
-
ApoEdeficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree
-
Nakashima Y, Plump AS, Raines EW, Breslow JL, Ross R. ApoEdeficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler Thromb. 1994;14:133-140.
-
(1994)
Arterioscler Thromb
, vol.14
, pp. 133-140
-
-
Nakashima, Y.1
Plump, A.S.2
Raines, E.W.3
Breslow, J.L.4
Ross, R.5
-
21
-
-
0027976942
-
Atherosclerosis in mice lacking apo E. Evaluation of lesional development and progression
-
Reddick RL, Zhang SH, Maeda N. Atherosclerosis in mice lacking apo E. Evaluation of lesional development and progression. Arterioscler Thromb. 1994;14:141-147.
-
(1994)
Arterioscler Thromb
, vol.14
, pp. 141-147
-
-
Reddick, R.L.1
Zhang, S.H.2
Maeda, N.3
-
22
-
-
0033535945
-
Myocardial infarction mediated by endothelin receptor signaling in hypercholesterolemic mice
-
Caligiuri G, Levy B, Pernow J, Thorén P, Hansson GK. Myocardial infarction mediated by endothelin receptor signaling in hypercholesterolemic mice. Proc Natl Acad Sci USA. 1999;96:6920-6924.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 6920-6924
-
-
Caligiuri, G.1
Levy, B.2
Pernow, J.3
Thorén, P.4
Hansson, G.K.5
-
23
-
-
0037155049
-
Loss of SR-BI expression leads to the early onset of occlusive atherosclerotic coronary artery disease, spontaneous myocardial infarctions, severe cardiac dysfunction, and premature death in apolipoprotein E-deficient mice
-
Braun A, Trigatti BL, Post MJ, Sato K, Simons M, Edelberg JM, Rosenberg RD, Schrenzel M, Krieger M. Loss of SR-BI expression leads to the early onset of occlusive atherosclerotic coronary artery disease, spontaneous myocardial infarctions, severe cardiac dysfunction, and premature death in apolipoprotein E-deficient mice. Circ Res. 2002;90:270-276.
-
(2002)
Circ Res
, vol.90
, pp. 270-276
-
-
Braun, A.1
Trigatti, B.L.2
Post, M.J.3
Sato, K.4
Simons, M.5
Edelberg, J.M.6
Rosenberg, R.D.7
Schrenzel, M.8
Krieger, M.9
-
24
-
-
36448943901
-
Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease
-
Fernández-Hernando C, Ackah E, Yu J, Suárez Y, Murata T, Iwakiri Y, Prendergast J, Miao RQ, Birnbaum MJ, Sessa WC. Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease. Cell Metab. 2007;6:446-457.
-
(2007)
Cell Metab
, vol.6
, pp. 446-457
-
-
Fernández-Hernando, C.1
Ackah, E.2
Yu, J.3
Suárez, Y.4
Murata, T.5
Iwakiri, Y.6
Prendergast, J.7
Miao, R.Q.8
Birnbaum, M.J.9
Sessa, W.C.10
-
25
-
-
2442591844
-
Macrophage-targeted overexpression of urokinase causes accelerated atherosclerosis, coronary artery occlusions, and premature death
-
Cozen AE, Moriwaki H, Kremen M, DeYoung MB, Dichek HL, Slezicki KI, Young SG, Véniant M, Dichek DA. Macrophage-targeted overexpression of urokinase causes accelerated atherosclerosis, coronary artery occlusions, and premature death. Circulation. 2004;109:2129-2135.
-
(2004)
Circulation
, vol.109
, pp. 2129-2135
-
-
Cozen, A.E.1
Moriwaki, H.2
Kremen, M.3
Deyoung, M.B.4
Dichek, H.L.5
Slezicki, K.I.6
Young, S.G.7
Véniant, M.8
Dichek, D.A.9
-
26
-
-
80053141377
-
Highlights of 10 years of immunology in Nature Reviews Immunology
-
Medzhitov R, Shevach EM, Trinchieri G, Mellor AL, Munn DH, Gordon S, Libby P, Hansson GK, Shortman K, Dong C, Gabrilovich D, Gabryšová L, Howes A, O'Garra A. Highlights of 10 years of immunology in Nature Reviews Immunology. Nat Rev Immunol. 2011;11:693-702.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 693-702
-
-
Medzhitov, R.1
Shevach, E.M.2
Trinchieri, G.3
Mellor, A.L.4
Munn, D.H.5
Gordon, S.6
Libby, P.7
Hansson, G.K.8
Shortman, K.9
Dong, C.10
Gabrilovich, D.11
Gabryšová, L.12
Howes, A.13
O'garra, A.14
-
27
-
-
0028142568
-
CAMP and tumor necrosis factor competitively regulate transcriptional activation through and nuclear factor binding to the cAMP-responsive element/activating transcription factor element of the endothelial leukocyte adhesion molecule-1 (E-selectin) promoter
-
De Luca LG, Johnson DR, Whitley MZ, Collins T, Pober JS. cAMP and tumor necrosis factor competitively regulate transcriptional activation through and nuclear factor binding to the cAMP-responsive element/activating transcription factor element of the endothelial leukocyte adhesion molecule-1 (E-selectin) promoter. J Biol Chem. 1994;269:19193-19196.
-
(1994)
J Biol Chem
, vol.269
, pp. 19193-19196
-
-
De Luca, L.G.1
Johnson, D.R.2
Whitley, M.Z.3
Collins, T.4
Pober, J.S.5
-
28
-
-
0031252641
-
TNF initiates E-selectin transcription in human endothelial cells through parallel TRAF-NF-kappa B and TRAF-RAC/ CDC42-JNK-c-Jun/ATF2 pathways
-
Min W, Pober JS. TNF initiates E-selectin transcription in human endothelial cells through parallel TRAF-NF-kappa B and TRAF-RAC/ CDC42-JNK-c-Jun/ATF2 pathways. J Immunol. 1997;159:3508-3518.
-
(1997)
J Immunol
, vol.159
, pp. 3508-3518
-
-
Min, W.1
Pober, J.S.2
-
29
-
-
0034746311
-
NF-kappaB: Pivotal mediator or innocent bystander in atherogenesis?
-
Collins T, Cybulsky MI. NF-kappaB: pivotal mediator or innocent bystander in atherogenesis? J Clin Invest. 2001;107:255-264.
-
(2001)
J Clin Invest
, vol.107
, pp. 255-264
-
-
Collins, T.1
Cybulsky, M.I.2
-
30
-
-
78650878363
-
Nf-kappab, inflammation, and metabolic disease
-
Baker RG, Hayden MS, Ghosh S. Nf-kappab, inflammation, and metabolic disease. Cell Metab. 2011;13:11-22
-
(2011)
Cell Metab
, vol.13
, pp. 11-22
-
-
Baker, R.G.1
Hayden, M.S.2
Ghosh, S.3
-
31
-
-
77953506250
-
SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis
-
Yu L, Ji W, Zhang H, Renda MJ, He Y, Lin S, Cheng EC, Chen H, Krause DS, Min W. SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis. J Exp Med. 2010;207:1183-1195.
-
(2010)
J Exp Med
, vol.207
, pp. 1183-1195
-
-
Yu, L.1
Ji, W.2
Zhang, H.3
Renda, M.J.4
He, Y.5
Lin, S.6
Cheng, E.C.7
Chen, H.8
Krause, D.S.9
Min, W.10
-
32
-
-
33748292990
-
Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis
-
He Y, Luo Y, Tang S, et al. Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis. J Clin Invest. 2006;116:2344-2355.
-
(2006)
J Clin Invest
, vol.116
, pp. 2344-2355
-
-
He, Y.1
Luo, Y.2
Tang, S.3
-
33
-
-
34247895799
-
Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions
-
Zhang H, Luo Y, Zhang W, He Y, Dai S, Zhang R, Huang Y, Bernatchez P, Giordano FJ, Shadel G, Sessa WC, Min W. Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions. Am J Pathol. 2007;170:1108-1120.
-
(2007)
Am J Pathol
, vol.170
, pp. 1108-1120
-
-
Zhang, H.1
Luo, Y.2
Zhang, W.3
He, Y.4
Dai, S.5
Zhang, R.6
Huang, Y.7
Bernatchez, P.8
Giordano, F.J.9
Shadel, G.10
Sessa, W.C.11
Min, W.12
-
34
-
-
79751485813
-
Mechanisms of leukocyte transendothelial migration
-
Muller WA. Mechanisms of leukocyte transendothelial migration. Annu Rev Pathol. 2011;6:323-344.
-
(2011)
Annu Rev Pathol
, vol.6
, pp. 323-344
-
-
Muller, W.A.1
-
35
-
-
20144385204
-
Toll-like receptor 4-dependent and-independent cytokine secretion induced by minimally oxidized low-density lipoprotein in macrophages
-
Miller YI, Viriyakosol S, Worrall DS, Boullier A, Butler S, Witztum JL. Toll-like receptor 4-dependent and-independent cytokine secretion induced by minimally oxidized low-density lipoprotein in macrophages. Arterioscler Thromb Vasc Biol. 2005;25:1213-1219.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 1213-1219
-
-
Miller, Y.I.1
Viriyakosol, S.2
Worrall, D.S.3
Boullier, A.4
Butler, S.5
Witztum, J.L.6
-
36
-
-
0030941113
-
An endothelial receptor for oxidized low-density lipoprotein
-
Sawamura T, Kume N, Aoyama T, Moriwaki H, Hoshikawa H, Aiba Y, Tanaka T, Miwa S, Katsura Y, Kita T, Masaki T. An endothelial receptor for oxidized low-density lipoprotein. Nature. 1997;386: 73-77.
-
(1997)
Nature
, vol.386
, pp. 73-77
-
-
Sawamura, T.1
Kume, N.2
Aoyama, T.3
Moriwaki, H.4
Hoshikawa, H.5
Aiba, Y.6
Tanaka, T.7
Miwa, S.8
Katsura, Y.9
Kita, T.10
Masaki, T.11
-
37
-
-
0032421731
-
Oxidized low-density lipoprotein increases the production of intracellular reactive oxygen species in endothelial cells: Inhibitory effect of lacidipine
-
Cominacini L, Garbin U, Pasini AF, Davoli A, Campagnola M, Pastorino AM, Gaviraghi G, Lo Cascio V. Oxidized low-density lipoprotein increases the production of intracellular reactive oxygen species in endothelial cells: inhibitory effect of lacidipine. J Hypertens. 1998;16:1913-1919.
-
(1998)
J Hypertens
, vol.16
, pp. 1913-1919
-
-
Cominacini, L.1
Garbin, U.2
Pasini, A.F.3
Davoli, A.4
Campagnola, M.5
Pastorino, A.M.6
Gaviraghi, G.7
Lo Cascio, V.8
-
38
-
-
0034724687
-
Oxidized low density lipoprotein (ox-LDL) binding to ox-LDL receptor-1 in endothelial cells induces the activation of NF-kappaB through an increased production of intracellular reactive oxygen species
-
Cominacini L, Pasini AF, Garbin U, Davoli A, Tosetti ML, Campagnola M, Rigoni A, Pastorino AM, Lo Cascio V, Sawamura T. Oxidized low density lipoprotein (ox-LDL) binding to ox-LDL receptor-1 in endothelial cells induces the activation of NF-kappaB through an increased production of intracellular reactive oxygen species. J Biol Chem. 2000;275:12633-12638.
-
(2000)
J Biol Chem
, vol.275
, pp. 12633-12638
-
-
Cominacini, L.1
Pasini, A.F.2
Garbin, U.3
Davoli, A.4
Tosetti, M.L.5
Campagnola, M.6
Rigoni, A.7
Pastorino, A.M.8
Lo Cascio, V.9
Sawamura, T.10
-
39
-
-
84855432213
-
Physiological effects of oxidized phospholipids and their cellular signaling mechanisms in inflammation
-
Greig FH, Kennedy S, Spickett CM. Physiological effects of oxidized phospholipids and their cellular signaling mechanisms in inflammation. Free Radic Biol Med. 2012;52:266-280.
-
(2012)
Free Radic Biol Med.
, vol.52
, pp. 266-280
-
-
Greig, F.H.1
Kennedy, S.2
Spickett, C.M.3
-
40
-
-
38749118269
-
The lectin-like oxidized low-density-lipoprotein receptor: A pro-inflammatory factor in vascular disease
-
Dunn S, Vohra RS, Murphy JE, Homer-Vanniasinkam S, Walker JH, Ponnambalam S. The lectin-like oxidized low-density-lipoprotein receptor: a pro-inflammatory factor in vascular disease. Biochem J. 2008;409:349-355.
-
(2008)
Biochem J
, vol.409
, pp. 349-355
-
-
Dunn, S.1
Vohra, R.S.2
Murphy, J.E.3
Homer-Vanniasinkam, S.4
Walker, J.H.5
Ponnambalam, S.6
-
41
-
-
4644310560
-
Role of oxidative modifications in atherosclerosis
-
Stocker R, Keaney JF Jr. Role of oxidative modifications in atherosclerosis. Physiol Rev. 2004;84:1381-1478.
-
(2004)
Physiol Rev
, vol.84
, pp. 1381-1478
-
-
Stocker, R.1
Keaney Jr., J.F.2
|