Steroid treatment in Ataxia-Telangiectasia induces alterations of functional magnetic resonance imaging during prono-supination task

European Journal of Paediatric Neurology

Volumn 17, Issue 2, 2013, Pages 135-140

  Quarantelli, Mario ^a   Giardino, Giuliana ^b   Prinster, Anna ^a,c   Aloj, Giuseppina ^b   Carotenuto, Barbara ^d   Cirillo, Emilia ^b   Marsili, Angela ^b   Salvatore, Elena ^b   Del Giudice, Ennio ^b   Pignata, Claudio ^b  

^a CNR   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c IRCCS SDN   (Italy)

^d Department of Biomorphological and Functional Sciences ^*  (Italy)

Author keywords

Ataxia Teleangiectasia; Betamethasone; fMRI

Indexed keywords

BETAMETHASONE;

ADOLESCENT; ARTICLE; ATAXIA TELANGIECTASIA; BODY POSTURE; CASE REPORT; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HAND; HUMAN; MALE; MOTOR CORTEX; MOTOR PERFORMANCE; MULTIPLE CYCLE TREATMENT; NUCLEAR MAGNETIC RESONANCE SCANNER; PILOT STUDY; PRIORITY JOURNAL; RATING SCALE; REST; SCALE FOR THE ASSESSMENT AND RATING OF ATAXIA; SCHOOL CHILD; VALIDATION PROCESS; VOXEL BASED MORPHOMETRY;

ADOLESCENT; ATAXIA TELANGIECTASIA; BETAMETHASONE; CHILD; FEMALE; GLUCOCORTICOIDS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MOTOR CORTEX; PILOT PROJECTS; POSTURE; PSYCHOMOTOR PERFORMANCE;

EID: 84875370751     PISSN: 10903798     EISSN: 15322130     Source Type: Journal    
DOI: 10.1016/j.ejpn.2012.06.002     Document Type: Article

References (38)

1. K. Savitsky, A. Bar-Shira, and S. Gilad A single ataxia telangiectasia gene with a product similar to PI-3 kinase Science 268 1995 1749 1753
2. K. Savitsky, S. Sfez, and D.A. Tagle The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species Hum Mol Genet 4 1995 2025 2032
3. S. Biton, A. Barzilai, and Y. Shiloh The neurological phenotype of ataxia-telangiectasia: solving a persistent puzzle DNA Repair 7 2008 1028 1038
4. H.H. Chun, and R.A. Gatti Ataxia-telangiectasia, an evolving phenotype DNA Repair 3 2004 1187 1196
5. R.A. Gatti, S. Becker-Catania, and H.H. Chun The pathogenesis of ataxia-telangiectasia. Learning from a Rosetta Stone Clin Rev Allergy Immunol 20 2001 87 108
6. T.O. Crawford, R.L. Skolasky, R. Fernandez, K.J. Rosquist, and H.M. Lederman Survival probability in ataxia telangiectasia Arch Dis Child 91 2006 610 611
7. M.F. Lavin, N. Gueven, S. Bottle, and R.A. Gatti Current and potential therapeutic strategies for the treatment of ataxia-telangiectasia Br Med Bull 81-82 2007 129 147
8. S. Buoni, R. Zanolli, L. Sorrentino, and A. Fois Betamethasone and improvement of neurological symptoms in ataxia-telangiectasia Arch Neurol 63 2006 1479 1482
9. T. Broccoletti, E. Del Giudice, and S. Amorosi Steroid-induced improvement of neurological signs in ataxia-telangiectasia patients Eur J Neurol 15 2008 223 228
10. T. Broccoletti, E. Del Giudice, and E. Cirillo Efficacy of very-low-dose betamethasone on neurological symptoms in ataxia-telangiectasia Eur J Neurol 18 2011 564 570
11. I. Russo, C. Cosentino, and E. Del Giudice In ataxia-teleangiectasia betamethasone response is inversely correlated to cerebellar atrophy and directly to antioxidative capacity Eur J Neurol 16 2009 755 759
12. N.A. Datson, M.C. Morsink, O.C. Meijer, and E.R. de Kloet Central corticosteroid actions: search for gene targets Eur J Pharmacol 583 2008 272 289
13. T. Schmitz-Hubsch, S. Tezenas du Montcel, and L. Baliko Scale for the assessment and rating of ataxia Neurology 66 2006 1717 1720
14. Y. Yang, and K. Herrup Loss of neuronal cell cycle control in ataxia-telangiectasia: a unified disease mechanism J Neurosci 25 2005 2522 2529
15. S. Katyal, and P.J. McKinnon DNA strand breaks, neurodegeneration and aging in the brain Mech Ageing Dev 129 2008 483 491
16. M. Habek, V.V. Brinar, M. Rados, I. Zadro, and K. Zarkovic Brain MRI abnormalities in ataxia telangiectasia Neurologist 14 2008 192 195
17. M. Kieslich, F. Hoche, and J. Reichenbach Extracerebellar MRI-lesions in ataxia telangiectasia go along with deficiency of the GH/IGF-1 axis, markedly reduced body weight, high ataxia scores and advanced age Cerebellum 9 2010 190 197
18. A. Poretti, N.I. Wolfa, and E. Boltshauser Differential diagnosis of cerebellar atrophy in childhood Eur J Paediatr Neurol 12 2008 155 167
19. F. Tavani, R.A. Zimmerman, and G.T. Berry Ataxia-telangiectasia: the pattern of cerebellar atrophy on MRI Neuroradiology 45 2003 315 319
20. L. Farina, C. Uggetti, and A. Ottolini Ataxia-telangiectasia: MR and CT findings J Comput Assist Tomogr 18 1994 724 727
21. F. Sardanelli, R.C. Parodi, and C. Ottonello Cranial MRI in ataxia-telangiectasia Neuroradiology 37 1995 77 82
22. P.N. Jayakumar, S. Desai, and P.K. Pal Functional correlates of incoordination in patients with spinocerebellar ataxia 1: a preliminary fMRI study J Clin Neurosci 15 2008 269 277
23. M.H. Parks, V.L. Morgan, and D.R. Pickens Brain fMRI activation associated with self-paced finger tapping in chronic alcohol-dependent patients Alcohol Clin Exp Res 27 2003 704 711
24. M.J. Henckens, G.A. van Wingen, M. Joëls, and G. Fernández Time-dependent corticosteroid modulation of prefrontal working memory processing PNAS 108 2011 5801 5806
25. Y. Komatsuzaki, G. Murakami, and T. Tsurugizawa Rapid spinogenesis of pyramidal neurons induced by activation of glucocorticoid receptors in adult male rat hippocampus Biochem Biophys Res Commun 335 2005 1002 1007
26. B.S. McEwen Plasticity of the hippocampus: adaptation to chronic stress and allostatic load Ann N Y Acad Sci 933 2001 265 277
27. B.S. McEwen Stress and the aging hippocampus Front Neuroendocrinol 20 1999 49 70
28. C. Liston, and W.B. Gan Glucocorticoids are critical regulators of dendritic spine development and plasticity in vivo PNAS 108 2011 16074 16079
29. B. Fritsch, J. Reis, and K. Martinowich Direct current stimulation promotes BDNF-dependent synaptic plasticity: potential implications for motor learning Neuron 66 2010 198 204
30. E.J. Huang, and L.F. Reichardt Trk receptors: roles in neuronal signal transduction Annu Rev Biochem 72 2003 609 642
31. E. Toscano, R. della Casa, and S. Mardy Multisystem involvement in congenital insensitivity to pain with anhidrosis (CIPA), a nerve growth factor receptor (Trk A)-related disorder Neuropediatrics 31 2000 39 41
32. F. Jeanneteau, M.J. Garabedian, and M.V. Chao Activation of Trk neurotrophin receptors by glucocorticoids provides a neuroprotective effect PNAS 105 2008 4862 4867
33. E.M. Prager, and L.R. Johnson Stress at the synapse: signal transduction mechanisms of adrenal steroids at neuronal membranes Sci Signal 2 2009 re5
34. H. Parfenova, R.A. Neff, and J.S. Alonso Cerebral vascular endothelial heme oxygenase: expression, localization, and activation by glutamate Am J Physiol Cell Physiol 281 2001 1954 1963
35. C. Kotsarini, P.D. Griffiths, I.D. Wilkinson, and N. Hoggard A systematic review of the literature on the effects of dexamethasone on the brain from in vivo human-based studies: implications for physiological brain imaging of patients with intracranial tumors Neurosurgery 67 2010 1799 1815
36. E.R. Cohen, K. Ugurbil, and S.G. Kim Effect of basal conditions on the magnitude and dynamics of the blood oxygenation level-dependent fMRI response J Cereb Blood Flow Metab 22 2002 1042 1053
37. L.J. Kemna, and S. Posse Effect of respiratory CO(2) changes on the temporal dynamics of the hemodynamic response in functional MR imaging Neuroimage 14 2001 642 649
38. N.Y. Oei, B.M. Elzinga, and O.T. Wolf Glucocorticoids decrease hippocampal and prefrontal activation during declarative memory retrieval in young men Brain Imaging Behav 1 2007 31 41