Betamethasone and improvement of neurological symptoms in ataxia-telangiectasia

Archives of Neurology

Volumn 63, Issue 10, 2006, Pages 1479-1482

  Buoni, Sabrina ^a   Zannolli, Raffaella ^a   Sorrentino, Livio ^b   Fois, Alberto ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b Pediatrics O U   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETAMETHASONE; METHYLPREDNISOLONE;

ARTICLE; ASTHMA; ATAXIA TELANGIECTASIA; CASE REPORT; CORTICOSTEROID THERAPY; DRUG SAFETY; HUMAN; INCREASED APPETITE; LONG TERM CARE; MALE; MOON FACE; NEUROLOGIC DISEASE; PRESCHOOL CHILD; PRIORITY JOURNAL; SIDE EFFECT; TREATMENT OUTCOME; WEIGHT GAIN;

ATAXIA; ATAXIA TELANGIECTASIA; BETAMETHASONE; CELL CYCLE PROTEINS; CEREBELLUM; CHILD, PRESCHOOL; CONJUNCTIVA; DNA-BINDING PROTEINS; DRUG ADMINISTRATION SCHEDULE; DRUG THERAPY, COMBINATION; GAIT DISORDERS, NEUROLOGIC; GLUCOCORTICOIDS; HUMANS; MALE; METHYLPREDNISOLONE; PROTEIN-SERINE-THREONINE KINASES; RECOVERY OF FUNCTION; TREATMENT OUTCOME; TUMOR SUPPRESSOR PROTEINS;

EID: 33749593471     PISSN: 00039942     EISSN: 15383687     Source Type: Journal    
DOI: 10.1001/archneur.63.10.1479     Document Type: Article

References (8)

1. McKinnon PJ. ATM and ataxia telangiectasia. EMBO Rep. 2004;5:772-776.
2. Lee Y, McKinnon PJ. ATM dependent apoptosis in the nervous system. Apoptosis. 2000;5:523-529.
3. Espinos-Armero C, Gonzalez-Cabo P, Palau-Martinez F. Autosomal recessive cerebellar ataxias: their classification, genetic features and pathophysiology. Rev Neurol. 2005;41:409-422.
4. Schimmer BP, Parker KL. Adrenocorticotropic hormone: adrenocortical steroid and their synthetic analogs: inhibitors of the synthesis and actions of adrenocortical hormones. In: Hardman JG, Limbird LE, Gilman AG, eds. Goodman and Gilman's the Pharmacological Basis of Therapeutics. 10th ed. New York, NY: McGraw-Hill Co; 2001:1649-1677.
5. Chrousos GP. The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. N Engl J Med. 1995;332:1351-1362.
6. Mitchell CD, Richards SM, Kinsey SE, Lilleyman J, Vora A, Eden TO; Medical Research Council Childhood Leukaemia Working Party. Benefit of dexamethasone compared with prednisolone for childhood acute lymphoblastic leukaemia: results of the UK Medical Research Council ALL97 randomized trial. Br J Haematol. 2005;129:734-745.
7. Poupard M. Ataxia-telangiectasia. In: Euro-Ataxia: European Federation of Hereditary Ataxia [newsletter 24]. 2003:7-9.
8. Uz T, Dwivedi Y, Qeli A, Peters-Golden M, Pandey G, Manev H. Glucocorticoid receptors are required for up-regulation of neuronal 5-lipoxygenase (5LOX) expression by dexamethasone. FASEB J. 2001;15:1792-1794.