Endothelialized microvasculature based on a biodegradable elastomer

Tissue Engineering

Volumn 11, Issue 1-2, 2005, Pages 302-309

  Fidkowski, Christina ^a   Kaazempur Mofrad, Mohammad R ^a,b   Borenstein, Jeffrey ^c   Vacanti, Joseph P ^b   Langer, Robert ^a,e   Wang, Yadong ^d  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c CHARLES STARK DRAPER LABORATORY   (United States)

^d GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^e Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADATION; BIOLOGICAL ORGANS; CELL CULTURE; CELLS; MICROELECTROMECHANICAL DEVICES; SILICON WAFERS; TISSUE;

BIODEGRADABLE ELASTOMERS; ENDOTHELIALIZED MICROVASCULATURE; POLY(GLYCEROL SEBACATE) (PGS); TISSUE-ENGINEERED ORGANS;

ELASTOMERS;

ELASTOMER; POLY(GLYCEROL SEBACATE); SILICON; UNCLASSIFIED DRUG;

ARTICLE; CAPILLARY; ENDOTHELIUM CELL; FLOW RATE; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TISSUE ENGINEERING;

BIOCOMPATIBLE MATERIALS; BIODEGRADATION, ENVIRONMENTAL; CELL ADHESION; CELL CULTURE TECHNIQUES; CELL LINE; CELL PROLIFERATION; ELASTOMERS; ENDOTHELIUM, VASCULAR; HUMANS; IMPLANTS, EXPERIMENTAL; MICROCIRCULATION; PERFUSION; SILICON; SURFACE PROPERTIES; TISSUE ENGINEERING; UMBILICAL VEINS;

EID: 17144431774     PISSN: 10763279     EISSN: None     Source Type: Journal    
DOI: 10.1089/ten.2005.11.302     Document Type: Article

References (16)

1. Langer, R.S., and Vacanti, J.P. Tissue engineering. Science 260, 920, 1993.
2. Vacanti, J.P., and Langer, R. Tissue engineering: The design and fabrication of living replacement devices for surgical reconstruction and transplantation. Lancet 354(Suppl. I), 32, 1999.
3. Langer, R., and Vacanti, J.P. Tissue engineering: The challenges ahead. Sci. Am. 280, 86, 1999.
4. Colton, C. Implantable biohybrid artificial organs. Cell Transplant. 4, 415, 1995.
5. Folkman, J., and Hochberg, M. Self-regulation of growth in three dimensions. J. Exp. Med. 138, 745, 1973.
6. Kaazempur-Mofrad, M.R., Weinberg, E.J., Borernstein, J.T., and Vacanti, J.P. Tissue engineering: Multi-scaled representation of tissue architecture and function. In: Deisboeck, T.S., Kresh, J.Y., and Kepler, K.B., eds. Complex Systems Science in Biomedicine. New York: Kluwer Academic-Plenum Publishers, 2004.
7. Wang, Y., Ameer, G.A., Sheppard, B.J., and Langer, R. A tough biodegradable elastomer. Nat. Biotechnol. 20, 602, 2002.
8. Borenstein, J.T., Terai, H., King, K.R., Weinburg, E.J., Kaazempur-Mofrad, M.R., and Vacanti, J.P. Microfabrication technology for vascularized tissue engineering. Biomed. Microdevices 4, 167, 2002.
9. Kaazempur-Mofrad, M.R., Vacanti, J.P., and Kamm, R.D. Computational modeling of blood flow and rheology in fractal microvascular networks. Comput. Fluid Solid Mech. 2, 864, 2001.
10. Griffith, L.G., Wu, B., Cima, M.J., Powers, M.J., Chaignaud, B., and Vacanti, J.P. In vitro organogenesis of liver tissue. Ann. N.Y. Acad. Sci. 831, 382, 1997.
11. Kim, S.S., Utsunomiya, H., Koski, J.A., Wu, B.M., Cima, M.J., Sohn, J., Mukai, K., Griffith, L.G., and Vacanti, J.P. Survival and function of hepatocytes on a novel three-dimensional synthetic polymer scaffold with an intrinsic network of channels. Ann. Surg. 228, 8, 1998.
12. Kaihara, S., Borenstein, J., Koka, R., Lalan, S., Ochoa, E.R., Ravens, M., Pien, H., Cunningham, B., and Vacanti, J.P. Silicon micromachining to tissue engineer branched vascular channels for liver fabrication. Tissue Eng. 6, 105, 2000.
13. McDonald, J.C., and Whitesides, G.M. Poly(dimethyl-siloxane) as a material for fabricating microfluidic devices. Acc. Chem. Res. 35, 491, 2002.
14. Ng, J.M.K., Stroock, A.D., and Whitesides, G.M. Components for integrated poly(dimethylsiloxane) microfluidic systems. Electrophoresis 23, 3461, 2002.
15. King, K.R., Terai, H., Wang, C.C., Vacanti, J.P., and Borenstein, J.T. Microfluidics for tissue engineering microvasculature: Endothelial cell culture. In: Proceedings of the Fifth International Conference on Miniaturized Chemical and Biochemical Analysis Systems, Monterey, CA, 2001, 247.
16. Wang, Y., Kim, Y., and Langer, RJ. In vivo degradation characteristics of poly(glycerol sebacate). Biomed. Mater. Res. 66A, 192, 2003.