Fluoxetine augments ventilatory CO2 sensitivity in Brown Norway but not Sprague Dawley rats

Respiratory Physiology and Neurobiology

Volumn 186, Issue 2, 2013, Pages 221-228

  Hodges, Matthew R ^a   Echert, Ashley E ^a   Puissant, Madeleine M ^a   Mouradian, Gary C ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

CO2 chemoreception; Control of breathing; SSRI

Indexed keywords

AMINE; CARBON DIOXIDE; FLUOXETINE;

AMBIENT AIR; ANIMAL EXPERIMENT; ARTICLE; BRAIN LEVEL; BROWN NORWAY RAT; CARBON DIOXIDE BREATHING; CHEMORECEPTOR; CONTROLLED STUDY; DRUG EFFECT; ELECTROCHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERCAPNIA; MALE; NONHUMAN; PLETHYSMOGRAPHY; PRIORITY JOURNAL; RAT; SPRAGUE DAWLEY RAT; TIDAL VOLUME;

ANIMALS; CARBON DIOXIDE; FLUOXETINE; HYPERCAPNIA; MALE; PULMONARY VENTILATION; RATS; RATS, INBRED BN; RATS, SPRAGUE-DAWLEY; RESPIRATORY MECHANICS; SEROTONIN; SEROTONIN UPTAKE INHIBITORS;

EID: 84875340882     PISSN: 15699048     EISSN: 18781519     Source Type: Journal    
DOI: 10.1016/j.resp.2013.02.020     Document Type: Article

References (32)

1. Annerbrink K., Olsson M., Hedner J., Eriksson E. Acute and chronic treatment with serotonin reuptake inhibitors exert opposite effects on respiration in rats: possible implications for panic disorder. Journal of Psychopharmacology 2010, 24:1793-1801.
2. Baker-Herman T.L., Bavis R.W., Dahlberg J.M., Mitchell A.Z., Wilkerson J.E., Golder F.J., Macfarlane P.M., Watters J.J., Behan M., Mitchell G.S. Differential expression of respiratory long-term facilitation among inbred rat strains. Respiratory Physiology and Neurobiology 2010, 170:260-267.
3. Blain G.M., Smith C.A., Henderson K.S., Dempsey J.A. Peripheral chemoreceptors determine the respiratory sensitivity of central chemoreceptors to CO(2). Journal of Physiology 2010, 588:2455-2471.
4. Blier P., de Montigny C., Chaput Y. Modifications of the serotonin system by antidepressant treatments: implications for the therapeutic response in major depression. Journal of Clinical Psychopharmacology 1987, 7:24S-35S.
5. Brenes J.C., Fornaguera J. The effect of chronic fluoxetine on social isolation-induced changes on sucrose consumption, immobility behavior, and on serotonin and dopamine function in hippocampus and ventral striatum. Behavioural Brain Research 2009, 198:199-205.
6. Cowley A.W., Stoll M., Greene A.S., Kaldunski M.L., Roman R.J., Tonellato P.J., Schork N.J., Dumas P., Jacob H.J. Genetically defined risk of salt sensitivity in an intercross of Brown Norway and Dahl S rats. Physiological Genomics 2000, 2:107-115.
7. Dias M.B., Li A., Nattie E. Focal CO2 dialysis in raphe obscurus does not stimulate ventilation but enhances the response to focal CO2 dialysis in the retrotrapezoid nucleus. Journal of Applied Physiology 2008, 105:83-90.
8. Drorbaugh J.E., Fenn W.O. A barometric method for measuring ventilation in newborn infants. Pediatrics 1955, 16:81-87.
9. Forster H.V., Martino P., Hodges M.R., Krause K., Bonis J., Davis S., Pan L.G. The carotid chemoreceptors are a major determinant of ventilatory CO2 sensitivity and of PaCO2 during eupneic breathing. Advances in Experimental Medicine and Biology 2007, 605:322-326.
10. Hodges M.R., Richerson G.B. Interaction between defects in ventilatory and thermoregulatory control in mice lacking 5-HT neurons. Respiratory Physiology and Neurobiology 2008, 164:350-357.
11. Hodges M.R., Richerson G.B. Medullary serotonin neurons and their roles in central respiratory chemoreception. Respiratory Physiology and Neurobiology 2010, 173:256-263.
12. Hodges M.R., Richerson G.B. The role of medullary serotonin (5-HT) neurons in respiratory control: contributions to eupneic ventilation, CO2 chemoreception, and thermoregulation. Journal of Applied Physiology 2010, 108:1425-1432.
13. Hodges M.R., Forster H.V., Papanek P.E., Dwinell M.R., Hogan G.E. Ventilatory phenotypes among four strains of adult rats. Journal of Applied Physiology 2002, 93:974-983.
14. Hodges M.R., Tattersall G., Harris M.B., McEvoy S., Richerson D., Deneris E.S., Johnson R.L., Chen Z.F., Richerson G.B. Defects in breathing and thermoregulation in mice with near-complete absence of central serotonin neurons. Journal of Neuroscience 2008, 28:2495-2505.
15. Hodges M.R., Best S., Richerson G.B. Altered ventilatory and thermoregulatory control in male and female adult Pet-1 null mice. Respiratory Physiology and Neurobiology 2011, 177:133-140.
16. Hodges M.R., Mouradian G.C., Miller J., Muere C., Forster H.V. Altered brainstem neuromodulators relevant to central chemoreceptor function in Brown Norway (BN) rats. FASEB Journal 2012, 26:894-895.
17. Jans L.A., Korte-Bouws G.A., Korte S.M., Blokland A. The effects of acute tryptophan depletion on affective behaviour and cognition in Brown Norway and Sprague Dawley rats. Journal of Psychopharmacology 2010, 24:605-614.
18. Kinkead R., Dupenloup L., Valois N., Gulemetova R. Stress-induced attenuation of the hypercapnic ventilatory response in awake rats. Journal of Applied Physiology 2001, 90:1729-1735.
19. Le Poul E., Boni C., Hanoun N., Laporte A.M., Laaris N., Chauveau J., Hamon M., Lanfumey L. Differential adaptation of brain 5-HT1A and 5-HT1B receptors and 5-HT transporter in rats treated chronically with fluoxetine. Neuropharmacology 2000, 39:110-122.
20. Lowry C.A., Hale M.W., Burke K.A., Renner K.J., Moore F.L. Fluoxetine potentiates the effects of corticotropin-releasing factor on locomotor activity and serotonergic systems in the roughskin newt, Taricha granulosa. Hormones and Behavior 2009, 56:177-184.
21. Mouradian G.C., Forster H.V., Hodges M.R. Acute and chronic effects of carotid body denervation (CBD) on ventilation and chemoreflexes in three rat strains. Journal of Physiology 2012, 590:3335-3347.
22. Mulkey D.K., Rosin D.L., West G., Takakura A.C., Moreira T.S., Bayliss D.A., Guyenet P.G. Serotonergic neurons activate chemosensitive retrotrapezoid nucleus neurons by a pH-independent mechanism. Journal of Neuroscience 2007, 27:14128-14138.
23. Olsson M., Annerbrink K., Bengtsson F., Hedner J., Eriksson E. Paroxetine influences respiration in rats: implications for the treatment of panic disorder. European Neuropsychopharmacology 2004, 14:29-37.
24. Peng Y.J., Yuan G., Jacono F.J., Kumar G.K., Prabhakar N.R. 5-HT evokes sensory long-term facilitation of rodent carotid body via activation of NADPH oxidase. Journal of Physiology 2006, 576:289-295.
25. Richerson G.B. Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis. Nature Reviews Neuroscience 2004, 5:449-461.
26. Sahin G., Guner I., Yelmen N., Yaman O., Mengi M., Simsek G., Sipahi S. Alterations of central hypercapnic respiratory response induced by acute central administration of serotonin re-uptake inhibitor, fluoxetine. Chinese Journal of Physiology 2011, 54:356-366.
27. Serretti A., Mandelli L. Antidepressants and body weight: a comprehensive review and meta-analysis. Journal of Clinical Psychiatry 2010, 71:1259-1272.
28. Strohl K.P., Thomas A.J., St J.P., Schlenker E.H., Koletsky R.J., Schork N.J. Ventilation and metabolism among rat strains. Journal of Applied Physiology 1997, 82:317-323.
29. Taylor N.C., Li A., Green A., Kinney H.C., Nattie E.E. Chronic fluoxetine microdialysis into the medullary raphe nuclei of the rat, but not systemic administration, increases the ventilatory response to CO2. Journal of Applied Physiology 2004, 97:1763-1773.
30. Thaler K.J., Morgan L.C., Van Noord M., Gaynes B.N., Hansen R.A., Lux L.J., Krebs E.E., Lohr K.N., Gartlehner G. Comparative effectiveness of second-generation antidepressants for accompanying anxiety, insomnia, and pain in depressed patients: a systematic review. Depression and Anxiety 2012, 29:495-505.
31. Voituron N., Shvarev Y., Menuet C., Bevengut M., Fasano C., Vigneault E., El Mestikawy S., Hilaire G. Fluoxetine treatment abolishes the in vitro respiratory response to acidosis in neonatal mice. PLoS ONE 2010, 5:e13644.
32. Yokoyama, T., Misuzu, Y.Y., Yamamoto, Y., in press. Immunohistochemical localization of tryptophan hydroxylase and serotonin transporter in the carotid body of the rat. Histochem. Cell. Biol.