Towards squalamine mimics: Synthesis and antibacterial activities of head-to-tail dimeric sterol-polyamine conjugates

Chemistry and Biodiversity

Volumn 10, Issue 3, 2013, Pages 385-393

  Chen, Wen Hua ^a,b   Wennersten, Christine ^c   Moellering, Robert C ^c   Regen, Steven L ^b  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b LEHIGH UNIVERSITY   (United States)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Antibacterial activity; Polyamines; Squalamine; Sterol polyamine conjugates, dimeric

Indexed keywords

ANTIINFECTIVE AGENT; SPERMINE DERIVATIVE; SQUALAMINE;

ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HYDROPHILICITY; NONHUMAN; STRUCTURE ACTIVITY RELATION;

EID: 84875288771     PISSN: 16121872     EISSN: 16121880     Source Type: Journal    
DOI: 10.1002/cbdv.201100431     Document Type: Article

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