Cytoprotective effect of epigallocatechin-3-gallate against deoxynivalenol-induced toxicity through anti-oxidative and anti-inflammatory mechanisms in HT-29 cells

Food and Chemical Toxicology

Volumn 56, Issue , 2013, Pages 110-118

  Kalaiselvi, Palaniswamy ^a   Rajashree, Krishnaswamy ^b   Bharathi Priya, Lohanathan ^a   Padma, Viswanadha Vijaya ^a  

^a BHARATHIAR UNIVERSITY   (India)

^b KUMARAGURU COLLEGE OF TECHNOLOGY   (India)

Author keywords

Antioxidant; Apoptosis; EGCG; Inflammation; Mycotoxin; Oxidative stress

Indexed keywords

CASPASE 3; CYCLOOXYGENASE 2; EPIGALLOCATECHIN GALLATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; POLYPHENOL; VOMITOXIN;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL STRAIN HT29; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME REGULATION; GASTROINTESTINAL TRACT; HUMAN; HUMAN CELL; INFLAMMATION; INTESTINE CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR MECHANICS; OXIDATIVE STRESS; PROTEIN EXPRESSION; STOMACH PROTECTION; TEA; UPREGULATION;

ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; APOPTOSIS; CASPASE 3; CATECHIN; CYCLOOXYGENASE 2; CYTOPROTECTION; FUSARIUM; HT29 CELLS; HUMANS; NF-KAPPA B; OXIDATIVE STRESS; POLYPHENOLS; TEA; TRICHOTHECENES; UP-REGULATION;

EID: 84875274773     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.01.042     Document Type: Article

References (46)

1. Aebi H. Catalase. Methods of Enzymatic Analysis 1974, 673-684. Academic Press, New York. H.U. Bergmeyer (Ed.).
2. Agarwal B.B., Takada Y., Shishodia S., Gutierrez A.M., Oomen O.V., Ichikawa H., Baba Y., Kumar A. Nuclear transcription factor NF-κB: role in biology and medicine. Indian J. Exp. Biol. 2004, 42:341-353.
3. Azcona-Olivara J.I., Ouyang Y., Murtha J., Chu F.S., Pestka J.J. Induction of cytokine mRNAs in mice after oral exposure to the trichothecene vomitoxin (deoxynivalenol): relationship to toxin distribution and protein synthesis inhibition. Toxicol. Appl. Pharmacol. 1995, 133:109-120.
4. Azcona-Olivara J.I., Ouyang Y.L., Warner R.L., Linz J.E., Pestka J.J. Effects of vomitoxin (deoxynivalenol) and cycloheximide on IL-2, 4, 5 and 6 secretion and mRNA levels in murine CD4+ cells. Food Chem. Toxicol. 1995, 33:433-441.
5. Bensassi F., Golli-Bennour E.E., Abid-Essefi S., Bouaziz C., Hajlaouib M.R., Bacha H. Pathway of deoxynivalenol-induced apoptosis in human colon carcinoma cells. Toxicology 2009, 264:104-109.
6. Bensassi F., Gallerne C., Sharaf El Dein O., Lemaire C., Hajlaoui M.R., Bacha H. Involvement of mitochondria-mediated apoptosis in deoxynivalenol cytotoxicity. Food Chem. Toxicol. 2012, 50:1680-1689.
7. Braicu C., Berindan-Neagoe I., Tudoran O., Balacescu O., Rugina D., Gherman C., Socaciu C., Irimie Al. In vitro evaluation of the chemoprotective action of flavan-3-ols against deoxynivalenol related toxicity. Arch. Zootech. 2009, 12:45-55.
8. Chen C., Shen G., Hebbar V., Hu R., Owuor E.D., Kong A.N. Epigallocatechin-3-gallate-induced stress signals in HT-29 human colon adenocarcinoma cells. Carcinogenesis 2003, 24:1369-1378.
9. Dragomir G., Huculeci R., Munteanu C., Ceapa C., Bodea L., Dinischiotu A. The effect of deoxynivalenol on hepatic cell line HepG2. Biotech. Anim. Husb. 2007, 23:583-588.
10. Grove J.F. Non-macrocyclic trichothecenes. Part 2. Prog. Chem. Org. Nat. Prod. 2000, 69:1-70.
11. Habig W.H., Pabst M.J., Jakoby W.B. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 1974, 249:7130-7139.
12. Heinecke L.F., Grzanna M.W., Au A.Y., Mochal C.A., Rashmir-Raven A., Frondoza C.G. Inhibition of cyclooxygenase-2 expression and prostaglandin E2 production in chondrocytes by avocado soybean unsaponifiables and epigallocatechin gallate. Osteoarthritis Cartilage 2010, 18:220-227.
13. Hissin P., Hilf R. A fluorometric method for determination of oxidised and reduced glutathione in tissues. Anal. Biochem. 1976, 74:214-226.
14. Ho H.Y., Wei T.T., Cheng M.L., Chiu D.T. Green tea polyphenol epigallocatechin-3-gallate protects cells against peroxynitrite-induced cytotoxicity: modulatory effect of cellular G6PD Status. J. Agric. Food Chem. 2006, 54:1638-1645.
15. Ishida I., Kohda C., Yanagawa Y., Miyaoka H., Shimamura T. Epigallocatechin gallate suppresses expression of receptor activator of NF-kB ligand (RANKL) in Staphylococcus aureus infection in osteoblast-like NRG cells. J. Med. Microbiol. 2007, 56:1042-1046.
16. Jia S.J., Jiang D.J., Hu C.P., Zhang X.H., Deng H.W., Li Y.J. Lysophosphatidylcholine -induced elevation of asymmetric dimethylarginine level by the NADPH oxidase pathway in endothelial cells. Vasc. Pharmacol. 2006, 44:143-148.
17. 2 in NF-κB activation. Free Radic. Biol. Med. 2008, 45:885-896.
18. Krishnaswamy R., Devaraj S.N., Padma V.V. Lutein protects HT-29 cells against deoxynivalenol-induced oxidative stress and apoptosis: prevention of NF-κB nuclear localization and down regulation of NF-κB and cyclo-oxygenase-2 expression. Free Radic. Biol. Med. 2010, 49:50-60.
19. Levine R.L., Garland D., Oliver C.N., Amici A., Climent I., Lenz A.G., Ahn B.W., Shaltiel S., Stadtman E.R. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol. 1990, 186:464-478.
20. Marasas W.F. Incidence of Fusarium species and the mycotoxins, deoxynivalenol and zearalenone, in corn produced in esophageal cancer areas in Transkei. J. Agric. Food Chem. 1979, 27:1108-1112.
21. Marchetti P., Hirsch T., Zamzami N., Castedo M., Decaudin D., Susin S.A., Masse B., Kroemer G. Mitochondrial permeability transition triggers lymphocyte apoptosis. J Immunol. 1996, 157:4830-4836.
22. Marklund S., Marklund G. Involvement of the superoxide anion radical in the autooxidation of pyrogallol and a convenient assay of superoxide dismutase. Eur. J. Biochem. 1974, 47:469-474.
23. Meiyanto E., Agustina D., Supardjan A.M., Da'i M. PVG-O induces apoptosis on T47D breast cancer cell line through caspase-3 activation. Jumal Kedokteran Yarsi 2007, 15:75-79.
24. Moon Y., Pestka J.J. Vomitoxin-induced cyclooxygenase-2 gene expression in macrophages mediated by activation of ERK and p38 but not JNK mitogen activated protein kinases. Toxicol. Sci. 2002, 69:373-382.
25. Moon Y., Pestka J.J. Cyclooxygenase-2 mediates interleukin-6 upregulation by vomitoxin (deoxynivalenol) in vitro and in vivo. Toxicol. Appl. Pharmacol. 2003, 187:80-88.
26. Mossman T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65:55-63.
27. Nasri T., Bosch R.R., Voorde S., Fink-Gremmels J. Deferential induction of apoptosis by type A and B trichothecenes in Jurkat T-lymphocytes. Toxicol. In Vitro 2006, 20:832-840.
28. Nieland A.A. Lactic acid dehydrogenase of heart muscle. Methods in Enzymology 1955, 394. Academic Press, New York.
29. Papp E., Nardai G., Söti C., Csermely P. Molecular chaperones, stress proteins and redox homeostasis. BioFactors 2003, 17:249-257.
30. Pestka J.J., Zhou H.R., Moon Y., Chung Y.J. Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: unraveling a paradox. Toxicol. Lett. 2004, 153:61-73.
31. Peters A.K., Van Londen K., Bergman A., Bohonowych J., Denison M.S., Van Den Berg M., Sanderson J.T. Effects of polybrominated diphenyl ethers on basal and TCDD-induced ethoxyresorufin activity and cytochrome P450-1A1 expression in MCF-7, HepG2, and H4IIE cells. Toxicol. Sci. 2004, 82:488-496.
32. Romeo L., Intrieri M., D'Agata V., Mangano N.G., Oriani G., Ontario M.L., Scapagnini G. The major green tea polyphenol, (-)-epigallocatechin-3- gallate, induces heme oxygenase in rat neurons and acts as an effective neuroprotective agent against oxidative stress. J. Am. Coll. Nutr. 2009, 28:492-499.
33. Rostom A., Dubé C., Lewin G., Tsertsvadze A., Barrowman N., Code C., Sampson M., Moher D. Nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors for primary prevention of colorectal cancer: a systematic review prepared for the US preventive services task force. Ann. Intern. Med. 2007, 146:376-389.
34. Rotruck J.T., Pope A.L., Ganther H.E., Swanson A.B., Hafeman D.G., Hoekstra W.G. Selenium: biochemical role as a component of glutathione peroxidase. Science 1973, 179:588-590.
35. Rotter B.A., Prelusky D.B., Pestka J.J. Toxicology of deoxynivalenol (vomitoxin) (invited review). J. Toxicol. Environ. Health 1996, 48:1-34.
36. Russo M., Spagnuolo C., Tedesco I., Russo G.L. Phytochemicals in cancer prevention and therapy: truth or dare?. Toxins 2010, 2:517-551.
37. Singh T., Katiyar S.K. Green tea catechins reduce invasive potential of human melanoma cells by targeting COX-2, PGE2 receptors and epithelial-to-mesenchymal transition. PLoS ONE 2011, 6:e25224.
38. Sobrova P., Adam V., Vasatkova A., Beklova M., Zeman L., Kizek R. Deoxynivalenol and its toxicity. Interdiscip. Toxicol. 2010, 3:94-99.
39. Stuehr D.J., Marletta M.A. Induction of nitrite/nitrate synthesis in murine macrophages by BCG infection, lymphokines, or interferon-gamma. J. Immunol. 1987, 139:518-525.
40. Sugiyama K., Kinoshita M., Kamata Y., Minai Y., Sugita-Konishi Y. (-)-Epigallocatechingallate suppresses the cytotoxicity induced by trichothecene mycotoxins in mouse cultural macrophages. Mycotoxin Res. 2011, 27:281-285.
41. Surh Y.J., Na H.K. NF-κB and Nrf2 as prime molecular targets for chemoprevention and cytoprotection with anti-inflammatory and antioxidant phytochemicals. Genes Nutr. 2008, 2:313-317.
42. Towbin H., Staehelin T., Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. 1979, 76:4350-4354.
43. Xu Q., Yang C.H., Liu Q., Jin X.F., Xu X.T., Tong J.L., Xiao S.D., Ran Z.H. Chemopreventive effect of epigallocatechin-3-gallate (EGCG) and folic acid on the N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced gastrointestinal cancer in rat model. J. Dig. Dis. 2011, 12:181-187.
44. Yao K., Ye P., Zhang L., Tan J., Tang X., Zhang Y. Epigallocatechin gallate protects against oxidative stress-induced mitochondria-dependent apoptosis in human lens epithelial cells. Mol. Vis. 2008, 14:217-223.
45. Zhou H.R., Lau A.S., Pestka J.J. Role of double-stranded RNA-activated protein kinase R (PKR) in deoxynivalenol-induced ribotoxic stress response. Toxicol. Sci. 2003, 74:335-344.
46. Zhou H.R., Islam Z., Pestka J.J. Induction of competing apoptotic and survival signaling pathways in the macrophage by the ribotoxic trichothecene deoxynivalenol. Toxicol. Sci. 2005, 87:113-122.