Vasoconstriction induced by G1, a G-protein-coupled oestrogen receptor1 (GPER-1) agonist, in the isolated perfused rat kidney

European Journal of Pharmacology

Volumn 702, Issue 1-3, 2013, Pages 71-78

  Kurt, Akif Hakan ^b   Buyukafsar, Kansu ^a  

^a MERSIN UNIVERSITY   (Turkey)

^b KAHRAMANMARAS SUTCU IMAM UNIVERSITY   (Turkey)

Author keywords

EGF; GPER 1; NR3A1; NR3A2; Oestrogen; Renal circulation; Rho kinase

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; ESTRADIOL; ESTROGEN RECEPTOR; FULVESTRANT; G PROTEIN COUPLED RECEPTOR; GENISTEIN; GF109203X; NIFEDIPINE; PHENYLEPHRINE; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; RHO KINASE; SAPONIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; KIDNEY; KIDNEY CORTEX; KIDNEY MEDULLA; MALE; NONHUMAN; PERFUSION PRESSURE; PRIORITY JOURNAL; RAT; RENAL ARTERY; VASOCONSTRICTION; VASODILATATION; WESTERN BLOTTING;

ANIMALS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CYCLOPENTANES; ESTRADIOL; ESTROGEN ANTAGONISTS; ESTROGENS; KIDNEY; MALE; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; QUINOLINES; RATS; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED; VASOCONSTRICTION;

EID: 84875264155     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.01.020     Document Type: Article

References (43)

1. C.G. Bologa, C.M. Revankar, S.M. Young, B.S. Edwards, J.B. Arterburn, A.S. Kiselyov, M.A. Parker, S.E. Tkachenko, N.P. Savchuck, L.A. Sklar, T.I. Oprea, and E.R. Prossnitz Virtual and biochemical screening converge on a selective agonist for GPR30 Nat. Chem. Biol. 2 2006 207 212
2. P.A. Bourassa, P.M. Milos, B.J. Gaynor, J.L. Breslow, and R.J. Aiello Estrogen reduces atherosclerotic lesion development in apolipoprotein E-deficient mice Proc. Natl. Acad. Sci. USA 93 1996 10022 10027
3. B.R.S. Broughton, A.A. Miller, and C.G. Sobey Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries Am. J. Physiol. Heart Circ. Physiol. 298 2010 H1055 H1061
4. K. Büyükafşar, O. Arikan, M. Ark, A. Seçilmiş, I. Un, and E. Şingirik Rho-kinase expression and its contribution to the control of perfusion pressure in the isolated rat mesenteric vascular bed Eur. J. Pharmacol. 485 2004 263 268
5. C. Carmeci, D.A. Thompson, H.Z. Ring, U. Francke, and R.J. Weigel Identification of a gene (GPR30) with homology to the G-protein-coupled receptor superfamily associated with estrogen receptor expression in breast cancer Genomics 45 1997 607 617
6. M.K. Dennis, R. Burai, C. Ramesh, W.K. Petrie, S.N. Alcon, T.K. Nayak, C.G. Bologa, A. Leitao, E. Brailoiu, E. Deliu, N.J. Dun, L.A. Sklar, H.J. Hathaway, J.B. Arterburn, T.I. Oprea, and E.R. Prossnitz In vivo effects of a GPR30 antagonist Nat. Biol. Chem. 5 2009 421 427
7. S.P. Duckles, and V.M. Miller Hormonal modulation of endothelial NO production Pflugers Arch. 459 2010 841 851
8. E.J. Filardo, J.A. Quinn, K.I. Bland, and A.R. Frackelton Estrogen-induced activation of Erk-1 and Erk-2 regulates the protein-coupled receptor homolog GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF Mol. Endocrinol. 14 2000 1649 1660
9. E.J. Filardo, and P. Thomas GPR30: a seven-transmembrane-spanning estrogen receptor that triggers EGF release Trends Endocrinol. Metab. 16 2005 362 367
10. J. Frasor, D.H. Barnett, J.M. Danes, R. Hess, A.F. Parlow, and B.S. Katzenellenbogen Response-specific and ligand dose-dependent modulation of estrogen receptor (ER) alpha activity by ERbeta in the uterus Endocrinology 144 2003 3159 3166
11. G.I. Gorodeski, T. Yang, M.N. Levy, J. Goldfarb, and W.H. Utian Effects of estrogen in vivo on coronary vascular resistance in perfused rabbit hearts Am. J. Physiol. 269 1995 R1333 R1338
12. K. Grandien, A. Berkenstam., and J.A. Gustafsson The estrogen receptor gene, promoter organization and expression Int. J. Biochem. Cell Biol. 29 1997 1343 1369
13. E. Haas, I. Bhattacharya, E. Brailoiu, M. Damjanović, G.C. Brailoiu, X. Gao, L. Mueller-Guerre, N.A. Marjon, A. Gut, R. Minotti, M.R. Meyer, K. Amann, E. Ammann, A. Perez-Dominguez, M. Genoni, D.J. Clegg, N.J. Dun, T.C. Resta, E.R. Prossnitz, and M. Barton Regulatory role of G protein-coupled estrogen receptor for vascular function and obesity Circ. Res. 104 2009 288 291
14. E. Haas, M.R. Meyer, U. Schurr, I. Bhattacharya, R. Minotti, H.H. Nguyen, A. Heigl, M. Lachat, M. Genoni, and M. Barton Differential effects of 17beta-estradiol on function and expression of estrogen receptor alpha, estrogen receptor beta, and GPR30 in arteries and veins of patients with atherosclerosis Hypertension 49 2007 1358 1363
15. G.G. Hazell, S.T. Yao, J.A. Roper, E.R. Prossnitz, A.M. O'Carroll, and S.J. Lolait Localisation of GPR30, a novel G protein-coupled oestrogen receptor, suggests multiple functions in rodent brain and peripheral tissues J. Endocrinol. 202 2009 223 236
16. R.A. Hees Estrogen in the adult male reproductive tract: a review Reprod. Biol. Endocrinol. 1 2003 52
17. M.D. Iafrati, R.H. Karas, M. Aronovitz, S. Kim, T.R. Sullivan Jr., D.B. Lubhan, T.F. O'Donnell Jr., K.S. Korach, and M.E. Mendelsohn Estrogen inhibits the vascular injury response in estrogen receptorβ-deficient mice Nat. Med. 3 1997 545 548
18. R.H. Karas, H. Schulten, G. Pare, M.J. Aronovitz, C. Ohlsson, J.A. Gustafsson, and M.E. Mendelsohn Effects of estrogen on the vascular injury response in estrogen receptor alpha, beta (double) knockout mice Circ. Res. 14 2001 534 539
19. S.H. Lindsey, K.A. Carver, E.R. Prossnitz, and M.C. Chappell Vasodilation in response to the GPR30 agonist G-1 is not different from estradiol in the mRen2.Lewis female rat J. Cardiovasc. Pharmacol. 57 2011 598 603
20. S.H. Lindsey, J.A. Cohen, K.B. Brosnihan, P.E. Gallagher, and M.C. Chappell Chronic treatment with the G protein-coupled receptor 30 agonist G-1 decreases blood pressure in ovariectomized mRen2.Lewis rats Endocrinology 150 2009 3753 3758
21. R.R. Magness, C.R. Parker Jr., and C.R. Rosenfeld Systemic and uterine response to chronic infusion of estradiol-17 beta Am. J. Physiol. 265 1993 E690 E698
22. U.E. Martensson, S.A. Salehi, S. Windahl, M.F. Gomez, K. Sward, J. Daszkiewicz-Nilsson, A. Wendt, N. Andersson, P. Hellstrand, P.O. Grände, C. Owman, C.J. Rosen, M.L. Adamo, I. Lundquist, P. Rorsman, B.O. Nilsson, C. Ohlsson, B. Olde, and L.M. Leeb-Lundberg Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice Endocrinology 150 2009 687 698
23. M.R. Meyer, O. Baretella, E.R. Prossnitz, and M. Barton Dilation of epicardial coronary arteries by the G protein-coupled estrogen receptor agonists G-1 and ICI 182,780 Pharmacology 86 2010 58 64
24. M.R. Meyer, E. Haas, and M. Barton Gender differences of cardiovascular disease: new perspectives for estrogen receptor signaling Hypertension 47 2006 1019 1026
25. M.R. Meyer, E.R. Prossnitz, and M. Barton The G protein-coupled estrogen receptor GPER/GPR30 as a regulator of cardiovascular function Vasc. Pharmacol. 55 2011 17 25
26. B.O. Nilsson, B. Olde, and L.M. Leeb-Lundber G protein-coupled oestrogen receptor 1 (GPER)/GPR30: a new player in cardiovascular and metabolic oestrogenic signalling Br. J. Pharmacol. 163 2011 1131 1139
27. G. Pare, A. Krust, R.H. Karas, S. Dupont, M. Aronovitz, P. Chambon, and M.E. Mendelsohn Estrogen receptor-alpha mediates the protective effects of estrogen against vascular injury Circ. Res. 90 2002 1087 1092
28. B. Ponnuchamy, and R.A. Khalil Cellular mediators of renal vascular dysfunction in hypertension Am. J. Physiol. Regul. Integr. Comp. Physiol. 296 2009 R1001 R1018
29. E.R. Prossnitz, L.A. Sklar, T.I. Oprea, and J.B. Arterburn GPR30: a novel therapeutic target in estrogen-related disease Trends Pharmacol. Sci. 29 2008 116 123
30. E.R. Prossnitz, and M. Maggiolini Mechanisms of estrogen signaling and gene expression via GPR30 Mol. Cell. Endocrinol. 308 2009 32 38
31. J.A. Quinn, C.T. Grabere, A.R. Frackelton Jr., M. Kim, J.E. Schwarzbauer, and E.J. Filardo Coordinate regulation of estrogen-mediated fibronectin matrix assembly and epidermal growth factor receptor transactivation by the G protein-coupled receptor, GPR30 Mol. Endocrinol. 23 2009 1052 1064
32. O.M. Reslan, and R.A. Khalil Vascular effects of estrogenic menopausal hormone therapy Rev. Rec. Cli. Trials 7 2012 47 70
33. C.M. Revankar, D.F. Cimino, L.A. Sklar, J.B. Arterburn, and E.R. Prossnitz A transmembrane intracellular estrogen receptor mediates rapid cell signaling Science 307 2005 1625 1630
34. E. Rodriguez, R. Lopez, A. Paez, F. Masso, and L.F. Montano 17Beta-estradiol inhibits the adhesion of leukocytes in TNF-alpha stimulated human endothelial cells by blocking IL-8 and MCP-1 secretion, but not its transcription Life Sci. 71 2002 2181 2193
35. C. Sanden, S. Broselid, L. Cornmark, K. Andersson, J. Daszkiewicz-Nilsson, U.E. Martensson, B. Olde, and L.M. Leeb-Lundberg G protein-coupled estrogen receptor 1/G protein-coupled receptor 30 localizes in the plasma membrane and traffics intracellularly on cytokeratin intermediate filaments Mol. Pharmacol. 79 2011 400 410
36. K. Satoh, Y. Fukumoto, and H. Shimokawa Rho-kinase: important new therapeutic target in cardiovascular diseases Am. J. Physiol. Heart Circ. Physiol. 301 2011 H287 H296
37. T. Simoncini, C. Scorticati, P. Mannella, A. Fadiel, M.S. Giretti, X.D. Fu, C. Baldacci, S. Garibaldi, A. Caruso, L. Fornari, F. Naftolin, and A.R. Genazzani Estrogen receptor alpha interacts with Galpha13 to drive actin remodeling and endothelial cell migration via the RhoA/Rho kinase/moesin pathway Mol. Endocrinol. 20 2006 1761 1771
38. E.M. Tsai, S.C. Wang, J.N. Lee, and M.C. Hung Akt activation by estrogen receptor-negative breast cancer cells Cancer Res. 61 2001 8390 9392
39. G. Vacca, A. Battaglia, E. Grossini, D.A. Mary, C. Molinari, and N. Surico 17β-Oestradiol on regional blood flow in anaesthetized pigs J. Physiol. 514 1999 875 884
40. A. Vivacqua, D. Bonofiglio, L. Albanito, A. Madeo, V. Rago, A. Carpino, A.M. Musti, D. Picard, S. Andò, and M. Maggiolini 17Beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30 Mol. Pharmacol. 70 2006 1414 1423
41. C. Wang, B. Dehghani, I.J. Magrisso, E.A. Rick, E. Bonhomme, D.B. Cody, L.A. Elenich, S. Subramanian, S.J. Murphy, M.J. Kelly, J.S. Rosenbaum, A.A. Vandenbark, and H. Offner GPR30 contributes to estrogen-induced thymic atrophy Mol. Endocrinol. 22 2008 636 648
42. C.P. Weiner, I. Lizasoain, S.A. Baylis, R.G. Knowles, I.G. Charles, and S. Moncada Induction of calcium-dependent nitric oxide synthases by sex hormones Proc. Natl. Acad. Sci. USA 91 1994 5212 5216
43. R.E. White Estrogen and vascular function Vasc. Pharmacol. 38 2002 73 80