Analysis of ciliary import

Methods in Enzymology

Volumn 524, Issue , 2013, Pages 75-89

  Dishinger, John F ^a   Kee, H Lynn ^a   Verhey, Kristen J ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Cilia; Ciliary import; FRAP; Microinjection; Nuclear import

Indexed keywords

DEXTRAN; RECOMBINANT PROTEIN;

ARTICLE; CELLULAR PARAMETERS; CILIARY IMPORT; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GENETIC TRANSFECTION; HUMAN; MAMMAL CELL; MICROINJECTION; MOLECULAR MECHANICS; MOLECULAR PROBE; NONHUMAN; PERMEABILITY; PLATING MEDIUM; PRIORITY JOURNAL;

EID: 84875263116     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/B978-0-12-397945-2.00005-6     Document Type: Chapter

References (34)

1. S.A. Adam, R.S. Marr, and L. Gerace Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors The Journal of Cell Biology 111 1990 807 816
2. N.F. Berbari, J.S. Lewis, G.A. Bishop, C.C. Askwith, and K. Mykytyn Bardet-Biedl syndrome proteins are required for the localization of G-protein-coupled receptors to primary cilia Proceedings of the National Academy of Sciences of the United States of America 105 2008 4242 4246
3. C. Boehlke, M. Bashkurov, A. Buescher, T. Krick, A.K. John, and R. Nitschke Differential role of rab proteins in ciliary trafficking: Rab23 regulates smoothened levels Journal of Cell Science 123 2010 1460 1467
4. I. Brailov, M. Bancila, M.J. Brisorgueil, M.C. Miquel, M. Hamon, and D. Verge Localization of 5-HT(6) receptors at the plasma membrane of neuronal cilia in the rat brain Brain Research 872 2000 271 275
5. P.D. Calvert, W.E. Schiesser, and E.N. Pugh Jr. Diffusion of a soluble protein, photoactivatable GFP, through a sensory cilium The Journal of General Physiology 135 2010 173 196
6. V. Cantagrel, J.L. Silhavy, S.L. Bielas, D. Swistun, S.E. Marsh, and J.Y. Bertrand Mutations in the cilia gene Arl13b lead to the classical form of Joubert syndrome The American Journal of Human Genetics 83 2008 170 179
7. T. Caspary, C.E. Larkins, and K.V. Anderson The graded response to sonic hedgehog depends on cilia architecture Developmental Cell 12 2007 767 778
8. S. Cevik, Y. Hori, O.I. Kaplan, K. Kida, T. Toivenon, and C. Foley-Fisher Joubert Syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in Caenorhabditis elegans The Journal of Cell Biology 188 2010 953 969
9. B. Chih, P. Liu, Y. Chinn, C. Chalouni, L.G. Komuves, and P.E. Hass A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain Nature Cell Biology 14 2012 61 72
10. B. Craige, C.C. Tsao, D.R. Diener, Y. Hou, K.F. Lechtreck, and J.L. Rosenbaum Cep290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content The Journal of Cell Biology 190 2010 927 940
11. J.F. Dishinger, H.L. Kee, P.M. Jenkins, S. Fan, T.W. Hurd, and J.W. Hammond Ciliary entry of the kinesin-2 motor Kif17 is regulated by importin-beta2 and RanGTP Nature Cell Biology 12 2010 703 710
12. S. Fan, V. Fogg, Q. Wang, X.W. Chen, C.J. Liu, and B. Margolis A novel Crumbs3 isoform regulates cell division and ciliogenesis via importin beta interactions The Journal of Cell Biology 178 2007 387 398
13. S.S. Francis, J. Sfakianos, B. Lo, and I. Mellman A hierarchy of signals regulates entry of membrane proteins into the ciliary membrane domain in epithelial cells The Journal of Cell Biology 193 2011 219 233
14. F.R. Garcia-Gonzalo, K.C. Corbit, M.S. Sirerol-Piquer, G. Ramaswami, E.A. Otto, and T.R. Noriega A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition Nature Genetics 43 2011 776 784
15. M. Handel, S. Schulz, A. Stanarius, M. Schreff, M. Erdtmann-Vourliotis, and H. Schmidt Selective targeting of somatostatin receptor 3 to neuronal cilia Neuroscience 89 1999 909 926
16. L. Hao, M. Thein, I. Brust-Mascher, G. Civelekoglu-Scholey, Y. Lu, and S. Acar Intraflagellar transport delivers tubulin isotypes to sensory cilium middle and distal segments Nature Cell Biology 13 2011 790 798
17. Y. Hori, T. Kobayashi, Y. Kikko, K. Kontani, and T. Katada Domain architecture of the atypical Arf-family GTPase Arl13b involved in cilia formation Biochemical and Biophysical Research Communications 373 2008 119 124
18. Q. Hu, L. Milenkovic, H. Jin, M.P. Scott, M.V. Nachury, and E.T. Spiliotis A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution Science 329 2010 436 439
19. T.W. Hurd, S. Fan, and B.L. Margolis Localization of retinitis pigmentosa 2 to cilia is regulated by importin beta2 Journal of Cell Science 124 2011 718 726
20. T.W. Hurd, W. Zhou, P. Jenkins, C.J. Liu, A. Swaroop, and H. Khanna The retinitis pigmentosa protein RP2 interacts with polycystin 2 and regulates cilia-mediated vertebrate development Human Molecular Genetics 19 2010 4330 4344
21. H. Ishikawa, and W.F. Marshall Ciliogenesis: Building the cell's antenna Nature Reviews. Molecular Cell Biology 12 2011 222 234
22. P.M. Jenkins, T.W. Hurd, L. Zhang, D.P. McEwen, R.L. Brown, and B. Margolis Ciliary targeting of olfactory CNG channels requires the CNGbeta1b subunit and the kinesin-2 motor protein, Kif17 Current Biology 16 2006 1211 1216
23. H.L. Kee, J.F. Dishinger, T.L. Blasius, C.J. Liu, B. Margolis, and K.J. Verhey A size-exclusion permeability barrier and nucleoporins characterize a ciliary pore complex that regulates transport into cilia Nature Cell Biology 14 2012 431 437
24. I. Lang, M. Scholz, and R. Peters Molecular mobility and nucleocytoplasmic flux in hepatoma cells The Journal of Cell Biology 102 1986 1183 1190
25. C.E. Larkins, G.D. Aviles, M.P. East, R.A. Kahn, and T. Caspary Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins Molecular Biology of the Cell 22 2011 4694 4703
26. A. Molla-Herman, R. Ghossoub, T. Blisnick, A. Meunier, C. Serres, and F. Silbermann The ciliary pocket: An endocytic membrane domain at the base of primary and motile cilia Journal of Cell Science 123 2010 1785 1795
27. M.S. Moore, and E.D. Schwoebel Nuclear import in digitonin-permeabilized cells Current Protocols in Cell Biology 2001 Chapter 11, Unit 11.7
28. J.R. Murrell, and D.D. Hunter An olfactory sensory neuron line, Odora, properly targets olfactory proteins and responds to odorants The Journal of Neuroscience 19 1999 8260 8270
29. M.V. Nachury, E.S. Seeley, and H. Jin Trafficking to the ciliary membrane: How to get across the periciliary diffusion barrier? Annual Review of Cell and Developmental Biology 26 2010 59 87
30. P.L. Paine Nucleocytoplasmic movement of fluorescent tracers microinjected into living salivary gland cells The Journal of Cell Biology 66 1975 652 657
31. G.H. Patterson Highlights of the optical highlighter fluorescent proteins Journal of Microscopy 243 2011 1 7
32. L. Sang, J.J. Miller, K.C. Corbit, R.H. Giles, M.J. Brauer, and E.A. Otto Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways Cell 145 2011 513 528
33. D. Takao, and S. Kamimura Geometry-specific heterogeneity of the apparent diffusion rate of materials inside sperm cells Biophysical Journal 98 2010 1582 1588
34. C.L. Williams, C. Li, K. Kida, P.N. Inglis, S. Mohan, and L. Semenec MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis The Journal of Cell Biology 192 2011 1023 1041