An olfactory sensory neuron line, odora, properly targets olfactory proteins and responds to odorants

Journal of Neuroscience

Volumn 19, Issue 19, 1999, Pages 8260-8270

  Murrell, Julie R ^a   Hunter, Dale D ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Conditional immortalization; Globose basal cell; Odorant signal transduction; Olfactory epithelium; Olfactory receptor protein; Olfactory sensory neuron

Indexed keywords

CALCIUM; CYCLIC NUCLEOTIDE; DOPAMINE; RECEPTOR PROTEIN; VOLATILE AGENT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL IMMORTALIZATION; CELL LINE; IMMUNOHISTOCHEMISTRY; MEMBRANE CHANNEL; NEWBORN; NONHUMAN; ODOR; OLFACTORY EPITHELIUM; OLFACTORY RECEPTOR; PRIORITY JOURNAL; PROTEIN TARGETING; RAT; SIGNAL TRANSDUCTION;

EID: 0033215992     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-19-08260.1999     Document Type: Article

References (59)

1. Barber PC, Lindsay RM (1982) Schwann cells of the olfactory nerves contain glial fibrillary acidic protein and resemble astrocytes. Neuroscience 7:3077-3090.
2. Bönigk W, Bradley J, Müller F, Sesti F, Boekhoff I, Ronnett GV, Kaupp UB, Frings S (1999) The native rat olfactory cyclic nucleotide-gated channel is composed of three distinct subunits. J Neurosci 19:5332-5347.
3. Bozza TC, Kauer JS (1998) Odorant response properties of convergent olfactory receptor neurons. J Neurosci 18:4560-4569.
4. Bradley J, Li J, Davidson N, Lester HA, Zinn K (1994) Heteromeric olfactory cyclic nucleotide-gated channels: a subunit that confers increased sensitivity to cAMP. Proc Natl Acad Sci USA 91:8890-8894.
5. Brunet LJ, Gold GH, Ngai J (1996) General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel. Neuron 17:681-693.
6. Brustle O, McKay RD (1996) Neuronal progenitors as tools for cell replacement in the nervous system. Curr Opin Neurobiol 6:688-695.
7. Buck L, Axel R (1991) A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell 65:175-187.
8. Caggiano ME, Kauer JS, Hunter DD (1994) Globose basal cells are neuronal progenitors in the olfactory epithelium: a lineage analysis using a replication-incompetent retrovirus. Neuron 13:339-352.
9. Calof AL, Chikaraishi DM (1989) Analysis of neurogenesis in a mammalian neuroepithelium: proliferation and differentiation of an olfactory neuron precursor in vitro. Neuron 3:115-127.
10. Calof AL, Mumm JS, Rim PC, Shou J (1998) The neuronal stem cell of the olfactory epithelium. J Neurobiol 36:190-205.
11. Cepko CL, Roberts BE, Mulligan RC (1984) Construction and applications of a highly transmissible murine retrovirus shuttle vector. Cell 37:1053-1062.
12. Coronas V, Feron F, Hen R, Sicard G, Jourdan F, Moyse E (1997a) In vitro induction of apoptosis or differentiation by dopamine in an immortalized olfactory neuronal cell line. J Neurochem 69:1870-1881.
13. Coronas V, Srivastava LK, Liang JJ, Jourdan F, Moyse E (1997b) Identification and localization of dopamine receptor subtypes in rat olfactory mucosa and bulb: a combined in situ hybridization and ligand binding radioautographic approach. J Chem Neuroanat 12:243-257.
14. Costanzo RM, Morrison EE (1989) Three-dimensional scanning electron microscopic study of the normal hamster olfactory epithelium. J Neurocytol 18:381-391.
15. Crews L, Hunter DD (1994) Neurogenesis in the olfactory epithelium. Perspect Dev Neurobiol 2:151-161.
16. Dhallan RS, Yau KW, Schrader KA, Reed RR (1990) Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons. Nature 347:184-187.
17. Duchamp-Viret P, Chaput MA, Duchamp A (1999) Odor response properties of rat olfactory receptor neurons. Science 284:2171-2174.
18. Farbman AI (1990) Olfactory neurogenesis: genetic or environmental controls? Trends Neurosci 13:362-365.
19. Fawcett JW, Geller HM (1998) Regeneration in the CNS: optimism mounts. Trends Neurosci 21:179-180.
20. Goldstein BJ, Schwob JE (1996) Analysis of the globose basal cell compartment in rat olfactory epithelium using GBC-1, a new monoclonal antibody against globose basal cells. J Neurosci 16:4005-4016.
21. Goldstein BJ, Wolozin BL, Schwob JE (1997) FGF2 suppresses neuronogenesis of a cell line derived from rat olfactory epithelium. J Neurobiol 33:411-428.
22. Graziadei PPC, Metcalf JF (1971) Autoradiographic and ultrastructural observations on the frog's olfactory mucosa. Z Zellforsch 116:305-318.
23. Graziadei PPC, Monti Graziadei GA (1979) Neurogenesis and neuron regeneration in the olfactory system of mammals. I. Morphological aspects of differentiation and structural organization of the olfactory sensory neurons. J Neurocytol 8:1-18.
24. Huard JM, Youngentob SL, Goldstein BJ, Luskin MB, Schwob JE (1998) Adult olfactory epithelium contains multipotent progenitors that give rise to neurons and non-neural cells. J Comp Neurol 400:469-486.
25. Hunter DD, Murphy MD, Olsson CV, Brunken WJ (1992) S-laminin expression in adult and developing retinae: a potential cue for photoreceptor morphogenesis. Neuron 8:399-413.
26. Jat PS, Cepko CL, Mulligan RC, Sharp PA (1986) Recombinant retroviruses encoding simian virus 40 large T antigen and polyomavirus large and middle T antigens. Mol Cell Biol 6:1204-1217.
27. Jat PS, Sharp PA (1989) Cell lines established by a temperature-sensitive simian virus 40 large-T-antigen gene are growth restricted at the non-permissive temperature. Mol Cell Biol 9:1672-1681.
28. Jones DT, Reed RR (1989) Golf: an olfactory neuron specific G protein involved in odorant signal transduction. Science 244:790-795.
29. Jones DT, Masters SB, Bourne HR, Reed RR (1990) Biochemical characterization of three stimulatory GTP-binding proteins. The large and small forms of Gs and the olfactory-specific G-protein, Golf. J Biol Chem 265:2671-2676.
30. Juilfs DM, Fulle HJ, Zhao AZ, Houslay MD, Garbers DL, Beavo JA (1997) A subset of olfactory neurons that selectively express cGMP-stimulated phosphodiesterase (PDE2) and guanylyl cyclase-D define a unique olfactory signal transduction pathway. Proc Natl Acad Sci USA 94:3388-3395.
31. Kauer JS (1991) Contributions of topography and parallel processing to odor coding in the vertebrate olfactory pathway. Trends Neurosci 14:79-85.
32. Kingston PA, Zufall F, Barnstable CJ (1996) Rat hippocampal neurons express genes for both rod retinal and olfactory cyclic nucleotide-gated channels: novel targets for cAMP/cGMP function. Proc Natl Acad Sci USA 93:10440-10445.
33. Krautwurst D, Yau KW, Reed RR (1998) Identification of ligands for olfactory receptors by functional expression of a receptor library. Cell 95:917-926.
34. Kuhn HG, Winkler J, Kempermann G, Thal LJ, Gage FH (1997) Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain. J Neurosci 17:5820-5829.
35. Libby RT, Hunter DD, Brunken WJ (1996) Developmental expression of laminin β2 in rat retina: further support for a role in rod morphogenesis. Invest Ophthalmol Vis Sci 37:1651-1661.
36. Liman ER, Buck LB (1994) A second subunit of the olfactory cyclic nucleotide-gated channel confers high sensitivity to cAMP. Neuron 13:611-621.
37. Mahanthappa NK, Schwarting GA (1993) Peptide growth factor control of olfactory neurogenesis and neuron survival in vitro: roles of EGF and TGF-βs. Neuron 10:293-305.
38. Malnic B, Hirono J, Sato T, Buck LB (1999) Combinatorial receptor codes for odors. Cell 96:713-723.
39. Mania-Farnell BL, Farbman AI, Bruch RC (1993) Bromocriptine, a dopamine D2 receptor agonist, inhibits adenylyl cyclase activity in rat olfactory epithelium. Neuroscience 57:173-180.
40. Margolis FL (1972) A brain protein unique to the olfactory bulb. Proc Natl Acad Sci USA 69:1221-1224.
41. McClintock TS, Landers TM, Gimelbrant AA, Fuller LZ, Jackson BA, Jayawickreme CK, Lerner MR (1997) Functional expression of olfactory-adrenergic receptor chimeras and intracellular retention of heterologously expressed olfactory receptors. Brain Res Mol Brain Res 48:270-278.
42. Moulton DG (1974) Dynamics of cell populations in the olfactory epithelium. Ann NY Acad Sci 237:52-61.
43. Nekrasova E, Sosinskaya A, Natochin M, Lancet D, Gat U (1996) Overexpression, solubilization and purification of rat and human olfactory receptors. Eur J Biochem 238:28-37.
44. Nickell WT, Norman AB, Wyatt LM, Shipley MT (1991) Olfactory bulb DA receptors may be located on terminals of the olfactory nerve. NeuroReport 2:9-12.
45. Pixley SK (1992) CNS glial cells support in vitro survival, division, and differentiation of dissociated olfactory neuronal progenitor cells. Neuron 8:1191-1204.
46. Raming K, Krieger J, Strotmann J, Boekhoff I, Kubick S, Baumstark C, Breer H (1993) Cloning and expression of odorant receptors. Nature 361:353-356.
47. Sautter A, Zong X, Hofmann F, Biel M (1998) An isoform of the rod photoreceptor cyclic nucleotide-gated channel β subunit expressed in olfactory neurons. Proc Natl Acad Sci USA 95:4696-4701.
48. Schild D (1988) Principles of odor coding and a neural network for odor discrimination. Biophys J 54:1001-1011.
49. Schild D, Restrepo D (1998) Transduction mechanisms in vertebrate olfactory receptor cells. Physiol Rev 78:429-466.
50. Schwartz Levey M, Chikaraishi DM, Kauer JS (1991) Characterization of potential precursor populations in the mouse olfactory epithelium using immunocytochemistry and autoradiography. J Neurosci 11:3556-3564.
51. Schwob JE, Huard JM, Luskin MB, Youngentob SL (1994) Retroviral lineage studies of the rat olfactory epithelium. Chem Senses 19:671-682.
52. Southern PJ, Berg P (1982) Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter. J Mol Appl Genet 1:327-341.
53. Talamo BR, Rudel R, Kosik KS, Lee VM, Neff S, Adelman L, Kauer JS (1989) Pathological changes in olfactory neurons in patients with Alzheimer's disease. Nature 337:736-739.
54. Touhara K, Sengoku S, Inaki K, Tsuboi A, Hirono J, Sato T, Sakano H, Haga T (1999) Functional identification and reconstitution of an odorant receptor in single olfactory neurons. Proc Natl Acad Sci USA 96:4040-4045.
55. Tsai RY, Reed RR (1997) Cloning and functional characterization of Roaz, a zinc finger protein that interacts with O/E-1 to regulate gene expression: implications for olfactory neuronal development. J Neurosci 17:4159-4169.
56. Vargas G, Lucero MT (1999) Dopamine modulates inwardly rectifying hyperpolarization-activated current (Ih) in cultured rat olfactory receptor neurons. J Neurophysiol 81:149-158.
57. Wang SS, Tsai RYL, Reed RR (1997) The characterization of the Olf-1/EBF-like HLH transcription factor family: implications in olfactory gene regulation and neuronal development. J Neurosci 17:4149-4158.
58. Weiss S, Reynolds BA, Vescovi AL, Morshead C, Craig CG, van der Kooy D (1996) Is there a neural stem cell in the mammalian forebrain? Trends Neurosci 19:387-393.
59. Zhao H, Ivic L, Otaki JM, Hashimoto M, Mikoshiba K, Firestein S (1998) Functional expression of a mammalian odorant receptor. Science 279:237-242.