Granulysin expression and the interplay of granulysin and perforin at the maternal-fetal interface

Journal of Reproductive Immunology

Volumn 97, Issue 2, 2013, Pages 186-196

  Veljkovic Vujaklija, Danijela ^a,b   Dominovic, Marin ^a   Gulic, Tamara ^a   Mahmutefendic, Hana ^a   Haller, Herman ^b   Saito, Shigeru ^c   Rukavina, Daniel ^a  

^a UNIVERSITY OF RIJEKA   (Croatia)

^b KBC RIJEKA   (Croatia)

^c UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Decidual lymphocytes; Granulysin; Natural killer (NK) cells; Perforin; Pregnancy

Indexed keywords

FAS LIGAND; GRANULYSIN; HLA C ANTIGEN; HLA G ANTIGEN; PERFORIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ADULT; ARTICLE; CONTROLLED STUDY; CYTOPLASM; DECIDUA; DENDRITIC CELL; FEMALE; FIRST TRIMESTER PREGNANCY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOCYTE; MACROPHAGE; MONONUCLEAR CELL; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; T LYMPHOCYTE;

ADULT; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; APOPTOSIS; CELL LINE; DECIDUA; FEMALE; HUMANS; KILLER CELLS, NATURAL; PERFORIN; PLACENTA; PREGNANCY; RNA, MESSENGER; YOUNG ADULT;

EID: 84875238073     PISSN: 01650378     EISSN: 18727603     Source Type: Journal    
DOI: 10.1016/j.jri.2012.11.003     Document Type: Article

References (35)

1. Anderson D.H., Sawaya M.R., Cascio D., Ernst W., Modlin R., Krensky A.M., et al. Granulysin crystal structure and a structure-derived lytic mechanism. J. Mol. Biol. 2003, 325(2):355-365.
2. Barman H., Walch M., Latinovic-Golic S., Dumrese C., Dolder M., Groscurth P., et al. Cholesterol in negatively charged lipid bilayers modulates the effect of the antimicrobial protein granulysin. J. Membr. Biol. 2006, 212:29-39.
3. Bolte S., Cordelières F.P. A guided tour into subcellular colocalization analysis in light microscopy. J. Microsc. 2006, 224(Pt 3):213-232.
4. Cacev T., Radosevic S., Krizanac S., Kapitanovic S. Influence of interleukin-8 and interleukin-10 on sporadic colon cancer development and progression. Carcinogenesis 2008, 29(8):1572-1580.
5. Clayberger C., Finn M.W., Wang T., Saini R., Wilson C., Barr V.A., et al. 15kDa granulysin causes differentiation of monocytes to dendritic cells but lacks cytotoxic activity. J. Immunol. 2012, 188(12):6119-6126.
6. Crncic T.B., Laskarin G., Frankovic K.J., Tokmadzic V.S., Strbo N., Bedenicki I., et al. Early pregnancy decidual lymphocytes beside perforin use Fas ligand (FasL) mediated cytotoxicity. J. Reprod. Immunol. 2007, 73(2):108-117.
7. Gansert J.L., Kiessler V., Engele M., Wittke F., Rollinghoff M., Krensky A.M., et al. Human NKT cells express granulysin and exhibit antimicrobial activity. J. Immunol. 2003, 170(6):3154-3161.
8. Hata A., Zerboni L., Sommer M., Kaspar A.A., Clayberger C., Krensky A.M., et al. Granulysin blocks replication of varicella-zoster virus and triggers apoptosis of infected cells. Viral Immunol. 2001, 14:125-133.
9. Kopcow H.D., Allan D.S., Chen X., Rybalov B., Andzelm M.M., Ge B., et al. Human decidual NK cells form immature activating synapses and are not cytotoxic. Proc. Natl. Acad. Sci. U.S.A. 2005, 102(43):15563-15568.
10. Lanier L.L. NK cell recognition. Annu. Rev. Immunol. 2005, 23:225-274.
11. Laskarin G., Redzovic A., Rubesa Z., Mantovani A., Allavena P., Haller H., et al. Decidual natural killer cell tuning by autologous dendritic cells. Am. J. Reprod. Immunol. 2008, 59:433-445.
12. Laskarin G., Redzovic A., Vukelic P., Veljkovic D., Gulic T., Haller H., et al. Phenotype of NK cells and cytotoxic/apoptotic mediators expression in ectopic pregnancy. Am. J. Reprod. Immunol. 2010, 65(5):347-358.
13. Le Bouteiller P., Rodriguez A.M., Mallet V., Girr M., Giullaudeux T., Lenfant F. Placental expression of HLA class I genes. Am. J. Reprod. Immunol. 1996, 35:216-225.
14. Lowin B., Peitsch M.C., Tschopp J. Perforin and granzymes: crucial effector molecules in cytolytic T lymphocyte and natural killer cells-mediated cytotoxicity. Curr. Top. Microbiol. Immunol. 1995, 198:1-24.
15. Mahmutefendic H., Blagojevic G., Ilic Tomas M., Kucic N., Lucin P. Segregation of open major histocompatibility class I conformers at the plasma membrane and during endosomal trafficking reveals conformation-based sorting in the endosomal system. Int. J. Biochem. Cell. Biol. 2011, 43(4):504-515.
16. Manning W.C., O'Farell S., Goralski T.J., Krensky A.M. Genomic structure and alternative splicing of 519, a gene expressed late after T cell activation. J. Immunol. 1992, 148(12):4036-4042.
17. Marchal-Bras-Goncalves R., Rouas-Freiss N., Connan F., Choppin J., Dausset J., Carosella E.D., et al. A soluble HLA-G protein that inhibits natural killer cell-mediated cytotoxicity. Transplant. Proc. 2001, 33(3):2355-2359.
18. McMaster M.T., Librach C.L., Zhou Y., Lim K.H., Janatpour M.J., DeMars R., et al. Human placental HLA-G expression is restricted to differentiated cytotrophoblasts. J. Immunol. 1995, 154:3771-3778.
19. Molvarec A., Shiozaki A., Ito M., Taldi G., Stenczer B., Szarka A., et al. Increased prevalence of peripheral blood granulysin-producing cytotoxic T lymphocytes in preeclampsia. J. Reprod. Immunol. 2011, 91:56-63.
20. Nakashima A., Shiozaki A., Myojo S., Ito M., Tatematstu M., Sakai M., et al. Granulysin produced by uterine natural killer cells induces apoptosis of extravillous trophoblast in spontaneous abortion. Am. J. Pathol. 2008, 173(3):653-664.
21. Obata-Onai A., Hashimoto S., Onai N., Kurachi M., Nagai S., Shizuno K., et al. Comprehensive gene expression analysis of human NK cells and CD8+ T lymphocytes. Int. Immunol. 2002, 14:1085-1098.
22. Ogawa K., Takamori Y., Suzuki K., Nagasawa M., Takano S., Kashara Y., et al. Granulysin in human serum as a marker of cell-mediated immunity. Eur. J. Immunol. 2003, 33:1925-1933.
23. Okada S., Li Q., Whitin J.C., Clayberger C., Krensky A.M. Intracellular mediators of granulysin-induced cell death. J. Immunol. 2003, 171:2556-2562.
24. Pena S.V., Hanson D.A., Carr B.A., Goralski T.J., Krensky A.M. Processing, subcellular localization and function of 519 (granulysin), a human late T cell activation molecule with homology to small, lytic. granule proteins. J. Immunol. 1997, 158(6):2680-2688.
25. Pena S.V., Krensky A.M. Granulysin, a new human cytolytic granule-associated protein with possible involvement in cell-mediated cytotoxicity. Semin. Immunol. 1997, 9:117-125.
26. Rabot M., Tabiasco J., Polgar B., Aguere-Girr M., Barrebi A., Bensussan A., et al. HLA class I/NK cell receptor interaction in early human decidua basalis: possible functional consequences. Chem. Immunol. Allergy 2005, 89:72-83.
27. Saini R.V., Wilson C., Finn M.W., Wang T., Krensky A.M., Clayberger C. Granulysin delivered by cytotoxic cells damages endoplasmic reticulum and activates caspase-7 in target cells. J. Immunol. 2011, 186:3497-3504.
28. Santoni A., Carlino C., Stabile H., Gismondi A. Mechanisms underlying recruitment and accumulation of decidual NK cells in uterus during pregnancy. Am. J. Reprod. Immunol. 2008, 59(5):417-424. (Review).
29. Stenger S., Hanson D.A., Teitelbaum R., Dewan P., Niazi K.R., Froelich C.J., et al. An antimicrobial activity of cytolytic T cells mediated by granulysin. Science 1998, 282:121-125.
30. Strbo N., Laskarin G., Bogovic Crncic T., Juretic Frankovic K., Bedenicki I., Sotosek Tokmadzic V., et al. Short term cytolytic mediators' expression in decidual lymphocytes is enhanced by interleukin-15. Am. J. Reprod. Immunol. 2006, 55:217-225.
31. Tabiasco J., Rabot M., Aguerre-Girr M., El Costa H., Berrebi A., Parant O., et al. Human decidual NK cells: unique phenotype and functional properties - a review. Placenta 2006, 27(9-10):1034-1035.
32. Tewary P., Yang D., de la Rosa G., Li Y., Finn M.W., Krensky A.M., et al. Granulysin activates antigen-presenting cells through TLR4 and acts as immune alarmin. Blood 2010, 116(18):3465-3474.
33. Veljkovic Vujaklija D., Gulic T., Sucic S., Nagata K., Ogawa K., Laskarin G., et al. First trimester pregnancy decidual natural killer cells contain and spontaneously release high quantities of granulysin. Am. J. Reprod. Immunol. 2011, 66(5):363-372.
34. Veljkovic Vujaklija D., Sucic S., Gulic T., Dominovic M., Rukavina D. Cell death mechanisms at the maternal-fetal interface; insights into the role of granulysin. Clin. Dev. Immunol. 2012, 2012:180272.
35. Winn V.D., Haimov-Kochman R., Paquet A.C., Yang Y.G., Madhusudhan M.S., Gormley M., et al. Gene expression profiling of the human maternal-fetal interface reveals dramatic changes between midgestation and term. Endocrinology 2007, 148:1059-1079.