메뉴 건너뛰기




Volumn 170, Issue 6, 2003, Pages 3154-3161

Human NKT cells express granulysin and exhibit antimycobacterial activity

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; ANTIINFECTIVE AGENT; CD1D ANTIGEN; GAMMA INTERFERON; GLYCOLIPID; GRANULYSIN; PEPTIDE DERIVATIVE; RECEPTOR SUBTYPE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

EID: 0037443555     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.170.6.3154     Document Type: Article
Times cited : (160)

References (55)
  • 1
    • 0029081822 scopus 로고
    • The CD1 family: A third lineage of antigen presenting molecules
    • Porcelli, S. 1995. The CD1 family: a third lineage of antigen presenting molecules. Adv. Immunol. 59:1.
    • (1995) Adv. Immunol. , vol.59 , pp. 1
    • Porcelli, S.1
  • 4
    • 0025975845 scopus 로고
    • Isolation and expression of cDNA encoding the murine homologues of CD1
    • Balk, S. P., P. A. Bleicher, and C. Terhorst. 1991. Isolation and expression of cDNA encoding the murine homologues of CD1. J. Immunol. 146:768.
    • (1991) J. Immunol. , vol.146 , pp. 768
    • Balk, S.P.1    Bleicher, P.A.2    Terhorst, C.3
  • 5
    • 0027142839 scopus 로고
    • Tissue distribution of the non-polymorphic major histocompatibility complex class I-like molecule, CD1d
    • Canchis, P. W., A. K. Bhan, S. B. Landau, L. Yang, S. P. Balk, and R. S. Blumberg. 1993. Tissue distribution of the non-polymorphic major histocompatibility complex class I-like molecule, CD1d. Immunology 80:561.
    • (1993) Immunology , vol.80 , pp. 561
    • Canchis, P.W.1    Bhan, A.K.2    Landau, S.B.3    Yang, L.4    Balk, S.P.5    Blumberg, R.S.6
  • 10
    • 0031573710 scopus 로고    scopus 로고
    • TCR Vα24 and Vβ11 coexpression defines a human NK1 T cell analog containing a unique Th0 subpopulation
    • Prussin, C., and B. Foster. 1997. TCR Vα24 and Vβ11 coexpression defines a human NK1 T cell analog containing a unique Th0 subpopulation. J. Immunol. 159:5862.
    • (1997) J. Immunol. , vol.159 , pp. 5862
    • Prussin, C.1    Foster, B.2
  • 11
    • 0029121546 scopus 로고
    • Natural T cells Cells that co-express NKRP-1 and TCR
    • Bix, M., and R. M. Locksley. 1995. Natural T cells. Cells that co-express NKRP-1 and TCR. J. Immunol. 155:1020.
    • (1995) J. Immunol. , vol.155 , pp. 1020
    • Bix, M.1    Locksley, R.M.2
  • 13
    • 0032547823 scopus 로고    scopus 로고
    • CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells
    • Spada, F. M., Y. Koezuka, and S. A. Porcelli. 1998. CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells. J. Exp. Med. 188:1529.
    • (1998) J. Exp. Med. , vol.188 , pp. 1529
    • Spada, F.M.1    Koezuka, Y.2    Porcelli, S.A.3
  • 14
    • 0034133499 scopus 로고    scopus 로고
    • + natural killer T cells activated by α-galactosylceramide (KRN7000) have cytotoxic anti-tumour activity through mechanisms distinct from T cells and natural killer cells
    • + natural killer T cells activated by α-galactosylceramide (KRN7000) have cytotoxic anti-tumour activity through mechanisms distinct from T cells and natural killer cells. Immunology 99:229.
    • (2000) Immunology , vol.99 , pp. 229
    • Nicol, A.1    Nieda, M.2    Koezuka, Y.3    Porcelli, S.4    Suzuki, K.5    Tadokoro, K.6    Durrant, S.7    Juji, T.8
  • 15
    • 0035884974 scopus 로고    scopus 로고
    • Human NKT cells mediate antitumor cytotoxicity directly by recognizing target cell CD1d with bound ligand or indirectly by producing IL-2 to activate NK cells
    • Metelitsa, L. S., O. V. Naidenko, A. Kant, H. W. Wu, M. J. Loza, B. Perussia, M. Kronenberg, and R. C. Seeger. 2001. Human NKT cells mediate antitumor cytotoxicity directly by recognizing target cell CD1d with bound ligand or indirectly by producing IL-2 to activate NK cells. J. Immunol. 167:3114.
    • (2001) J. Immunol. , vol.167 , pp. 3114
    • Metelitsa, L.S.1    Naidenko, O.V.2    Kant, A.3    Wu, H.W.4    Loza, M.J.5    Perussia, B.6    Kronenberg, M.7    Seeger, R.C.8
  • 17
    • 0034327173 scopus 로고    scopus 로고
    • Cutting edge: CD1d deficiency impairs murine host defense against the spirochete, Borrelia burgdorferi
    • Kumar, H., A. Belperron, S. W. Barthold, and L. K. Bockenstedt. 2000. Cutting edge: CD1d deficiency impairs murine host defense against the spirochete, Borrelia burgdorferi. J. Immunol. 165:4797.
    • (2000) J. Immunol. , vol.165 , pp. 4797
    • Kumar, H.1    Belperron, A.2    Barthold, S.W.3    Bockenstedt, L.K.4
  • 21
    • 0035145423 scopus 로고    scopus 로고
    • Characterization of murine lung dendritic cells infected with Mycobacterium tuberculosis
    • Gonzalez-Juarrero, M., and I. M. Orme. 2001. Characterization of murine lung dendritic cells infected with Mycobacterium tuberculosis. Infect. Immun. 69:1127.
    • (2001) Infect. Immun. , vol.69 , pp. 1127
    • Gonzalez-Juarrero, M.1    Orme, I.M.2
  • 23
    • 0034669917 scopus 로고    scopus 로고
    • CTL-mediated killing of intracellular Mycobacterium tuberculosis is independent of target cell nuclear apoptosis
    • Thoma-Uszynski, S., S. Stenger, and R. L. Modlin. 2000. CTL-mediated killing of intracellular Mycobacterium tuberculosis is independent of target cell nuclear apoptosis. J. Immunol. 165:5773.
    • (2000) J. Immunol. , vol.165 , pp. 5773
    • Thoma-Uszynski, S.1    Stenger, S.2    Modlin, R.L.3
  • 24
    • 0034292330 scopus 로고    scopus 로고
    • CD1d on myeloid dendritic cells stimulates cytokine secretion from and cytolytic activity of Vα24JαQ T cells: A feedback mechanism for immune regulation
    • Yang, O. O., F. K. Racke, P. T. Nguyen, R. Gausling, M. E. Severino, H. F. Horton, M. C. Byrne, J. L. Strominger. and S. B. Wilson. 2000. CD1d on myeloid dendritic cells stimulates cytokine secretion from and cytolytic activity of Vα24JαQ T cells: a feedback mechanism for immune regulation. J. Immunol. 165:3756.
    • (2000) J. Immunol. , vol.165 , pp. 3756
    • Yang, O.O.1    Racke, F.K.2    Nguyen, P.T.3    Gausling, R.4    Severino, M.E.5    Horton, H.F.6    Byrne, M.C.7    Strominger, J.L.8    Wilson, S.B.9
  • 28
    • 0031569218 scopus 로고    scopus 로고
    • Processing, subcellular localization, and function of 519 (granulysin), a human late T cell activation molecule with homology to small, lytic, granule proteins
    • Pena, S. V., D. A. Hanson, B. A. Carr, T. J. Goralski, and A. M. Krensky. 1997. Processing, subcellular localization, and function of 519 (granulysin), a human late T cell activation molecule with homology to small, lytic, granule proteins. J. Immunol. 158:2680.
    • (1997) J. Immunol. , vol.158 , pp. 2680
    • Pena, S.V.1    Hanson, D.A.2    Carr, B.A.3    Goralski, T.J.4    Krensky, A.M.5
  • 29
    • 0021243251 scopus 로고
    • In situ identification of cells in human leprosy granulomas with monoclonal antibodies to interleukin 2 and its receptor
    • Modlin, R. L., F. M. Hofman, D. A. Horwitz, L. A. Husmann, S. Gillis, C. R. Taylor, and T. H. Rea. 1984. In situ identification of cells in human leprosy granulomas with monoclonal antibodies to interleukin 2 and its receptor. J. Immunol. 132:3085.
    • (1984) J. Immunol. , vol.132 , pp. 3085
    • Modlin, R.L.1    Hofman, F.M.2    Horwitz, D.A.3    Husmann, L.A.4    Gillis, S.5    Taylor, C.R.6    Rea, T.H.7
  • 30
    • 0023948482 scopus 로고
    • Immunohistology of tuberculous adenitis in symptomatic HIV infection
    • Shen, J. Y., P. F. Barnes, T. H. Rea, and P. R. Meyer. 1988. Immunohistology of tuberculous adenitis in symptomatic HIV infection. Clin. Exp. Immunol. 72:186.
    • (1988) Clin. Exp. Immunol. , vol.72 , pp. 186
    • Shen, J.Y.1    Barnes, P.F.2    Rea, T.H.3    Meyer, P.R.4
  • 31
    • 0034531244 scopus 로고    scopus 로고
    • Low expression level but potent antigen presenting function of CD1d on monocyte lineage cells
    • Spada, F. M., F. Borriello, M. Sugita, G. F. Watts, Y. Koezuka, and S. A. Porcelli. 2000. Low expression level but potent antigen presenting function of CD1d on monocyte lineage cells. Eur. J. Immunol. 30:3468.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 3468
    • Spada, F.M.1    Borriello, F.2    Sugita, M.3    Watts, G.F.4    Koezuka, Y.5    Porcelli, S.A.6
  • 32
    • 0032971371 scopus 로고    scopus 로고
    • The CD1 system: Antigen-presenting molecules for T cell recognition of lipids and glycolipids
    • Porcelli, S. A., and R. L. Modlin. 1999. The CD1 system: antigen-presenting molecules for T cell recognition of lipids and glycolipids. Annu. Rev. Immunol. 17:297.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 297
    • Porcelli, S.A.1    Modlin, R.L.2
  • 34
    • 0031127454 scopus 로고    scopus 로고
    • Granulysin, a new human cytolytic granule-associated protein with possible involvement in cell-mediated cytotoxicity
    • Pena, S. V., and A. M. Krensky. 1997. Granulysin, a new human cytolytic granule-associated protein with possible involvement in cell-mediated cytotoxicity. Semin. Immunol. 9:117.
    • (1997) Semin. Immunol. , vol.9 , pp. 117
    • Pena, S.V.1    Krensky, A.M.2
  • 38
    • 0019993875 scopus 로고
    • Human large granular lymphocytes and natural killing ultrastructural studies of strontium-induced degranulation
    • Neighbour, P. A., H. S. Huberman, and Y. Kress. 1982. Human large granular lymphocytes and natural killing ultrastructural studies of strontium-induced degranulation. Eur. J. Immunol. 12:588.
    • (1982) Eur. J. Immunol. , vol.12 , pp. 588
    • Neighbour, P.A.1    Huberman, H.S.2    Kress, Y.3
  • 39
    • 0034234609 scopus 로고    scopus 로고
    • + CTL from lungs of Mycobacterium tuberculosis-infected mice express perforin in vivo and lyse infected macrophages
    • + CTL from lungs of Mycobacterium tuberculosis-infected mice express perforin in vivo and lyse infected macrophages. J. Immunol. 165:353.
    • (2000) J. Immunol. , vol.165 , pp. 353
    • Serbina, N.V.1    Liu, C.C.2    Scanga, C.A.3    Flynn, J.L.4
  • 41
    • 0033870526 scopus 로고    scopus 로고
    • Comparison of the T cell patterns in leprous and cutaneous sarcoid granulomas: Presence of Vα24-invariant natural killer T cells in T-cell-reactive leprosy together with a highly biased T cell receptor Vα repertoire
    • Mempel, M., B. Flageul, F. Suarez, C. Ronet, L. Dubertret, P. Kourilsky, G. Gachelin, and P. Musette. 2000. Comparison of the T cell patterns in leprous and cutaneous sarcoid granulomas: presence of Vα24-invariant natural killer T cells in T-cell-reactive leprosy together with a highly biased T cell receptor Vα repertoire. Am. J. Patrol. 157:509.
    • (2000) Am. J. Patrol. , vol.157 , pp. 509
    • Mempel, M.1    Flageul, B.2    Suarez, F.3    Ronet, C.4    Dubertret, L.5    Kourilsky, P.6    Gachelin, G.7    Musette, P.8
  • 43
    • 0034746796 scopus 로고    scopus 로고
    • + natural killer T cells by α-galactosylceramide results in development of Th1 response and local host resistance in mice infected with Cryptococcus neoformans
    • + natural killer T cells by α-galactosylceramide results in development of Th1 response and local host resistance in mice infected with Cryptococcus neoformans. Infect. Immun. 69:213.
    • (2001) Infect. Immun. , vol.69 , pp. 213
    • Kawakami, K.1    Kinjo, Y.2    Yara, S.3    Koguchi, Y.4    Uezu, K.5    Nakayama, T.6    Taniguchi, M.7    Saito, A.8
  • 45
    • 0035424543 scopus 로고    scopus 로고
    • NK cells and NKT cells in innate defense against viral infections
    • Biron, C. A., and L. Brossay. 2001. NK cells and NKT cells in innate defense against viral infections. Curr. Opin. Immunol. 13:458.
    • (2001) Curr. Opin. Immunol. , vol.13 , pp. 458
    • Biron, C.A.1    Brossay, L.2
  • 46
    • 0036839648 scopus 로고    scopus 로고
    • Activation of NKT cells protects mice from tuberculosis
    • Chackerian, A., J. Alt, A. Perers, and S. M. Behar. 2002. Activation of NKT cells protects mice from tuberculosis. Infect. Immun. 70:6302.
    • (2002) Infect. Immun. , vol.70 , pp. 6302
    • Chackerian, A.1    Alt, J.2    Perers, A.3    Behar, S.M.4
  • 47
    • 0032194116 scopus 로고    scopus 로고
    • Down-regulation of CD1 on antigen-presenting cells by infection with Mycobacterium tuberculosis
    • Stenger, S., K. R. Niazi, and R. L. Modlin. 1998. Down-regulation of CD1 on antigen-presenting cells by infection with Mycobacterium tuberculosis. J. Immunol. 161:3582.
    • (1998) J. Immunol. , vol.161 , pp. 3582
    • Stenger, S.1    Niazi, K.R.2    Modlin, R.L.3
  • 49
    • 0027360333 scopus 로고
    • An essential role for interferon-γ in resistance to Mycobacterium tuberculosis infection
    • Flynn, J. L., J. Chan, K. J. Triebold, D. K. Dalton, T. A. Stewart, and B. R. Bloom. 1993. An essential role for interferon-γ in resistance to Mycobacterium tuberculosis infection. J. Exp. Med. 178:2249.
    • (1993) J. Exp. Med. , vol.178 , pp. 2249
    • Flynn, J.L.1    Chan, J.2    Triebold, K.J.3    Dalton, D.K.4    Stewart, T.A.5    Bloom, B.R.6
  • 50
    • 0035826721 scopus 로고    scopus 로고
    • Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-α/β
    • Manca, C., L. Tsenova, A. Bergtold, S. Freeman, M. Tovey, J. M. Musser, C. E. Barry III, V. H. Freedman, and G. Kaplan. 2001. Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-α/β. Proc. Natl. Acad. Sci. USA 98:5752.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 5752
    • Manca, C.1    Tsenova, L.2    Bergtold, A.3    Freeman, S.4    Tovey, M.5    Musser, J.M.6    Barry C.E. III7    Freedman, V.H.8    Kaplan, G.9
  • 52
    • 0023899617 scopus 로고
    • + T lymphocytes in intracellular microbial infections
    • + T lymphocytes in intracellular microbial infections. Immunol. Today 9:168.
    • (1988) Immunol. Today , vol.9 , pp. 168
    • Kaufmann, S.H.E.1
  • 54
    • 0036735859 scopus 로고    scopus 로고
    • Prolonged IFN-γ-producing NKT response induced with α-galactosylceramide-loaded DCs
    • Fujii, S., K. Shimizu, M. Kronenberg, and R. M. Steinman. 2002. Prolonged IFN-γ-producing NKT response induced with α-galactosylceramide-loaded DCs. Nat. Immunol, 3:867.
    • (2002) Nat. Immunol, , vol.3 , pp. 867
    • Fujii, S.1    Shimizu, K.2    Kronenberg, M.3    Steinman, R.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.