Cypermethrin induced damage in genomic DNA and histopathological changes in brain and haematotoxicity in rats: The protective effect of sesame oil

Brain Research Bulletin

Volumn 92, Issue , 2013, Pages 76-83

  Hussien, Hend M ^a   Abdou, Heba M ^a   Yousef, Mokhtar I ^b  

^a Alexandria University Faculty Of Science   (Egypt)

^b ALEXANDRIA UNIVERSITY   (Egypt)

Author keywords

Brain; Cypermethrin; Genomic DNA; Histology; Lipid peroxidation; Rats; Sesame oil

Indexed keywords

ACETYLCHOLINESTERASE; ALBUMIN; AMINE OXIDASE (FLAVIN CONTAINING); CHOLESTEROL; CIPERMETHRIN; GENOMIC DNA; GLUTATHIONE; NEUROPROTECTIVE AGENT; PROTEIN; SESAME SEED OIL; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRAIN PROTECTION; BRAIN TOXICITY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DNA DAMAGE; DNA FRAGMENTATION; ENZYME ACTIVITY; FEMALE; HISTOPATHOLOGY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CONTENT; RAT; TREATMENT DURATION; TREATMENT RESPONSE; TRIACYLGLYCEROL BLOOD LEVEL;

ACETYLCHOLINESTERASE; ANIMALS; BLOOD CELL COUNT; BODY WEIGHT; BRAIN; BRAIN INJURIES; DISEASE MODELS, ANIMAL; DNA DAMAGE; FEMALE; GENOMICS; GLUTATHIONE; GLUTATHIONE PEROXIDASE; INSECTICIDES; LIPID PEROXIDATION; MONOAMINE OXIDASE; NEUROPROTECTIVE AGENTS; ORGAN SIZE; PYRETHRINS; RATS; RATS, WISTAR; SESAME OIL; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 84875237469     PISSN: 03619230     EISSN: 18732747     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2011.10.020     Document Type: Article

References (59)

1. Adham K.G., Khairalla A., Abu-Shabana M., Addel-Mguid N., Abd El-Mmoneim A. Environmental stress in Lake Maryut and physiological response of Tilapia zilli Gerv. J. Environ. Sci. Health 1997, A32:2585-2598.
2. Assayed M.E., Khalaf A.A., Salem H.A. Protective effects of garlic extract and vitamin C against in vivo cypermethrin-induced cytogenetic damage in rat bone-marrow. Mutat. Res. 2010, 702:1-7.
3. Bagchi D., Bagchi M., Hassoun E.A., Stohs S.J. In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate deidrogenase leakage by selected pesticides. Toxicology 1995, 104:129-140.
4. Barger A.M. The complete blood cell count: a powerful diagnostic tool. Vet. Clin. Small Anim. 2003, 33:1207-1222.
5. Barzilai A., Yamamoto K.I. DNA damage responses to oxidative stress. DNA Repair 2004, 3:1109-1115.
6. Beutler E., Duron O., Kelly B.M. An improved method for the detection of blood glutathione. J. Lab. Clin. Med. 1963, 61:882-888.
7. Bolognesi C. Genotoxicity of pesticides: a review of human biomonitoring studies. Mutat. Res. 2003, 543:251-272.
8. Chiu D.T.Y., Stults F.H., Tappel A.L. Purification and properties of rat lung soluble glutathione peroxidase. Biochim. Biophys. Acta 1976, 445:558-566.
9. Cui Y., Guo J., Xu B., Chen Z. Potential of chlorpyrifos and cypermethrin forming DNA adducts. Mutat. Res. 2006, 604:36-41.
10. El-Hossary G.G., Mansour S.M., Mohamed A.S. Neurotoxic effects of chlorpyrifos and the possible protective role of antioxidant supplements: an experimental study. J. Appl. Sci. Res. 2009, 5:1218-1222.
11. Ellman G.L., Courtney K.D., Anders V.J.R., Featherstone R.M. A new rapid colorimetric determination of acetylcholinesterase activity. Biochem. Pharmacol. 1961, 7:88-95.
12. Esterbauer H., Cheeseman K.H. Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Methods Enzymol. 1990, 186:407-421.
13. Fowler J., Volkow N., Wang G., Pappas N., Lagon J., Mac-Gregor R., Alexoff D. Neuropharmacological action of cigarette smoke: brain monoamine oxidase B (MAO B) inhibition. J. Add. Dis. 1998, 17:23-34.
14. Gabbianelli R., Falcioni G., Nasuti C., Cantalamessa F. Cypermethrin-induced plasma membrane perturbation on erythrocytes from rats: reduction of fl{ligature}uidity in the hydrophobic core and in glutathione peroxidase activity. Toxicology 2002, 175:91-101.
15. Gabbianelli R., Nasuti C., Falcioni G., Cantalamessa F. Lyphocyte DNA damage in rats exposed to pyrethroids effect of supplementation with vitamins E and C. Toxicology 2004, 203:17-26.
16. Giray B., Gurbay A., Hincal F. Cypermethrin-induced oxidative stress in rat brain and liver is prevented by Vitamin E or allopurinol. Toxicol. Lett. 2001, 118:139-146.
17. Glass R. Chronic and long-term effects of pesticides use in agriculture: current knowledge and limits. Toxicol. Lett. 2008, 180:S21.
18. Habig W.H., Pabst M.J., Jakoby W.B. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 1974, 249:7130-7139.
19. Hsu D.Z., Liu M.Y. Effects of sesame oil on oxidative stress after the onset of sepsis in rats. Shock 2004, 22:582-585.
20. Hsu D.Z., Chen K.T., Chien S.P., Ya-Hui Li Y.H., Bu-Miin Huang B.M., Yin-Ching Chuang Y.C., Liu M.Y. Sesame oil attenuates acute iron-induced lipid peroxidation associated hepatic damage in mice. Shock 2006, 26:625-630.
21. Hughes B.J., Forsell J.H., Sleight S.D., Kuo C., Shull L.R. Assessment of pentachlorophenol toxicity in newborn calves: clinicopathology and tissue resdues. J. Anim. Sci. 1985, 61:1587-1603.
22. Institoris L., Undeger U., Siroki O., Nehez M., Desi I. Comparison of detection sensitivity of immuno- and genotoxicological effects of subacute cypermethrin and permethrin exposure in rats. Toxicology 1999, 137:47-55.
23. Jayaratnam J., Maroni M. Organophosphorus compounds. Toxicology 1994, 91:15-27.
24. Jin Y., Zheng S., Pu Y., Shu L., Sun L., Liu W., Fu Z. Cypermethrin has the potential to induce hepatic oxidative stress, DNA damage and apoptosis in adult zebrafish (Danio rerio). Chemosphere 2011, 82:398-404.
25. Kakko I., Toimela T., Tahti H. The synaptosomal membrane bound ATPase as a target for the neurotoxic effects of pyrethroids, permethrin and cypermethrin. Chemosphere 2003, 51:475-480.
26. Kale M., Rathore N., John S., Bhatnagar D. Lipid peroxidative damage on pyrethroid exposure and lterations in antioxidant status in rat erythrocytes: a possible involvement of reactive oxygen species. Toxicol. Lett. 1999, 105:197-205.
27. Khan S.M., Sobti R.C., Kataria L. Pesticide-induced alteration in mice hepato-oxidative status and protective effects of black tea extract. Clin. Chim. Acta 2005, 358:131-138.
28. Khan A., Faridi H.A.M., Ali M., Khan M.Z., Siddique M., Hussain I. Effects of cypermethrin on some clinicohemato-biochemical and pathological parameters in male dwarf goats (Capra hircus). Exp. Toxicol. Pathol. 2009, 61:151-160.
29. Khillare Y.K., Wagh S.B. Acute toxicity of pesticides in the freshwater fish Barbus stigma: histopathology of the stomach. Uttar Pradesh J. Zool. 1988, 8:176-179.
30. Latuszynska J., Luty S., Raszewski G., Przebirowska D., Tokarska-Rodak M. Neurotoxic effect of dermally applied chlorpyrifos and cypermethrin. Revesibility of changes. Ann. Agric. Environ. Med. 2003, 10:197-201.
31. Lillie R.D. Histopathological technique and practical histochemistry 1965, The Blakistar Division of Mc Grow-Hill Book Co, New York, Toronto, London. 3rd ed.
32. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin Phenol Reagent. J. Biol. Chem. 1951, 193:269-275.
33. Mandal A., Chakraborty S., Lahiri P. Hematological changes produced by lindane (-HCH) in six species of birds. Toxicology 1996, 40:103-111.
34. Miller S.A., Dykes D.D., Polesky H.F. A Simple salting out procedure for extracting DNA from human nucleated cells. Nucl. Acids Res. 1988, 16:1215.
35. Misra H.P., Fridovich I. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J. Biol. Chem. 1972, 247:3170-3175.
36. Patel S., Bajpayee M., Pandey A.K., Parmar D., Dhawan A. In vitro induction of cytotoxicity and DNA strand breaks in CHO cells exposed to cypermethrin, pendimethalin and dichlorvos. Toxicol. In Vitro 2007, 21:1409-1418.
37. Pi J., Zhang Q., Fu J.G., Woods C.G., Hou Y., Corkey B.E., Collins S., Andersen M.E. ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function. Toxicol. Appl. Pharmacol. 2010, 244:77-83.
38. Rahman M.F., Siddiqui M.K.J., Mahboob M., Mustafa M. Hematological and hepatotoxic effects of isoprocarb in chicken. J. Appl. Toxicol. 1990, 10:187-192.
39. Rivarola V.A., Balegno H.F. Effect of 2,4-dichlorophenxyacetic acid on polyamine synthesis in Chinese hamster ovary cells. Toxicol. Lett. 1991, 56:151-157.
40. Sandler M., Reveley M., Glover V. Human platelets monoamine oxidase activity in health and disease: a review. J. Clin. Pathol. 1981, 34:292-302.
41. Sankar P., Telang A.G., Manimaran A. Curcumin protects against cypermethrin-induced genotoxicity in rats. Environ. Toxicol. Pharmacol. 2010, 30:289-291.
42. SAS (Statistical Analysis System) SAS User's Guide: Statistics, Version 5 1986, SAS Inst., Inc., Cary, NC, USA.
43. Saxena P., Saxena A.K. Cypermethrin induced biochemical alterations in the blood of albino rats. Jordan J. Biol. Sci. 2010, 3:111-114.
44. Saxena P.N., Chauhan L.K.S., Gupta S.K. Cytogenetic effects of formulation of cypermethrin in root meristem cells of Allium sativum: spectroscopic basis of chromosome damage. Toxicology 2005, 216:244-252.
45. Sayim F., Yavasoglu N.ü.K., Uyanikgil Y. Neurotoxic effects of cypermethrin in wister rats: a haematological, biochemical and histopathological study. J. Health Sci. 2005, 51:300-307.
46. Shakoori A.R., Aziz F., Alam J., Ali S.S. Toxic effects of talastar, a new synthetic pyrethroid, on blood and liver of rabbit. Pakistan J. Zool. 1990, 23:289-300.
47. P. Sankar, A.G. Telang, A. Manimaran, Protective effect of curcumin on cypermethrin-induced oxidative stress in Wistar rats, Exp. Toxicol. Pathol., in press. doi:10.1016/j.etp.2010.11.003.
48. Sood R. Medical Laboratory Technology Method and Interpretations 2006, Jaypee Brothers Medical Publishers (P) Ltd., New Delhi, 723 pp. 5th ed.
49. Steel R.G.D., Torrie J.H. Principle and Procedure of Statistics. A Biometrical Approach 1981, Mc Gvaus-Hill Book Company, New York, USA. 2nd ed.
50. Suja K.P., Jayalekshmy A., Arumughan C. Free radical scavenging behavior of antioxidant compounds of sesame (Sesamum indicum L.) in DPPH system. J. Agric. Food Chem. 2004, 52:912-915.
51. Suman G., Naravaneni R., Jamil K. In vitro cytogenetic studies of cypermethrin on human lymphocytes. Indian J. Exp. Biol. 2005, 44:233-239.
52. Undeger U., Basaran N. Effects of pesticides on human peripheral lymphocytes in vitro: induction of DNA damage. Arch. Toxicol. 2005, 79:169-176.
53. Wang W.N., Zhou J., Wang P., Tian T.T., Zheng Y., Liu Y., Mai W.J., Wang A.L. Oxidative stress, DNA damage and antioxidant enzyme gene expression in the Pacific white shrimp, Litopenaeus vannamei when exposed to acute pH stress. Comp. Biochem. Physiol. Toxicol. Pharmacol. 2009, 150:428-435.
54. Woo S., Yum S., Kim D.W., Park H.S. Transcripts level responses in a marine medaka (Oryzias javanicus) exposed to organophosphorus pesticide. Comp. Biochem. Phys. Toxicol. Pharmacol. 2009, 149:427-432.
55. Xu J.B., Yuan X.F., Lang P.Z. Determination of catalase activity and catalase inhibition by ultraviolet spectrophotometry. Chin. Environ. Chem. 1997, 16:73-76.
56. Yousef M.I., El-Demerdash F.M., Al-Salhen K.S. Protective role of isoflavones against the toxic effect of cypermethrin on semen quality and testosterone levels of rabbits. J. Environ. Sci. Health 2003, B38:463-478.
57. Yousef M.I., El-Demerdash F.M., Kamel K.I., Al-Salhen K.S. Changes in some hematological and biochemical indices of rabbits induced by isoflavones and cypermethrin. Toxicology 2003, 189:223-234.
58. Yousef M.I., Salem M.H., Ibrahim H.Z., Helmi S., Seehy M.A., Bertheussen K. Toxic effect of carbofuran and glyphosate on semen characteristics in rabbits. J. Environ. Sci. Health 1995, B30:513-534.
59. Zatta P., Nicosia V., Zambenedetti P. Evaluation of MAO activities on murine neuroblastoma cells upon acute or chronic treatment with aluminum(III) or tacrine. Neurochem. Int. 1998, 32:273-279.