CCL21 attenuates HSV-induced inflammation through up-regulation of CD8+ memory cells

Immunobiology

Volumn 218, Issue 4, 2013, Pages 579-590

  Choi, Bunsoon ^a   Lim, Hyun Chul ^a   Lee, Eun So ^a   Anower, A K M Mostafa ^a   Sohn, Seonghyang ^a,b  

^a Ajou University   (South Korea)

^b Brain Korea 21 Project for Medical Science   (South Korea)

Author keywords

Beh et's disease; CCL21; CCR7; CD8+ memory T cells; Herpes simplex virus induced inflammation; Mouse model

Indexed keywords

CD8 ANTIGEN; CHEMOKINE RECEPTOR CCR7; COMPLEMENTARY DNA; HEAT SHOCK PROTEIN 65; HERMES ANTIGEN; L SELECTIN; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; SECONDARY LYMPHOID TISSUE CHEMOKINE;

ADULT; ANIMAL CELL; ARTICLE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HERPES SIMPLEX VIRUS; HSV-INDUCED INFLAMMATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLAMMATION; LYMPHOCYTE HOMING; LYMPHOID TISSUE; MALE; MEMORY CELL; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYMPTOMATOLOGY; UPREGULATION;

ADULT; ANIMALS; BEHCET SYNDROME; CD8-POSITIVE T-LYMPHOCYTES; CERCOPITHECUS AETHIOPS; CHEMOKINE CCL21; DISEASE MODELS, ANIMAL; FEMALE; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HUMANS; IMMUNOLOGIC MEMORY; INFLAMMATION; MALE; MICE; MICE, INBRED ICR; MIDDLE AGED; RECEPTORS, CCR7; UP-REGULATION; VERO CELLS;

EID: 84875232670     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2012.07.003     Document Type: Article

References (48)

1. Bang D., Cho Y.H., Choi H.J. Detection of herpes simplex virus DNA by polymerase chain reaction in genital ulcer of patients with Behçet's disease. Proceedings of 7th International Conference on Behçet's Disease 1997, 74-76. Pub Adhoua, Tunis. M. Hamza (Ed.).
2. Behcet H. Ueber rezidivierende, apthöse, durch ein virus verusachte geschwüre am mund, am auge und an den genitalen. Dermatol. Wochenschr. 1937, 36:1152-1157.
3. Britschgi M.R., Favre S., Luther S.A. CCL21 is sufficient to mediate DC migration, maturation and function in the absence of CCL19. Eur. J. Immunol. 2010, 40:1266-1271.
4. Bruhl H., Mack M., Niedermeier M., Lochbaum D., Scholmerich J., Straub R.H. Functional expression of the chemokine receptor CCR7 on fibroblast-like synoviocytes. Rheumatology (Oxford) 2008, 47(12):1771-1774.
5. Campbell J.J., Butcher E.C. Chemokines in tissue-specific and microenvironment-specific lymphocyte homing. Curr. Opin. Immunol. 2000, 12:336-341.
6. Cyster J.G. Chemokines and cell migration in secondary lymphoid organs. Science 1999, 286:2098-2102.
7. Davalos-misslitz A.C., Rieckenberg J., Willenzon S. Generalized multi-organ autoimmunity in CCR7-deficient mice. Eur. J. Immunol. 1997, 37:613-622.
8. Dieu M.C., Vanbervliet B., Vicari A., Bridon J.M., Oldham E., Ait-Yahia S. Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites. J. Exp. Med. 1998, 188:373-386.
9. Direskeneli H., Ergun T., Yavuz S., Hamuryudan V., Eksioglu-Demiralp E. Thalidomide has both anti-inflammatory and regulatory effects in Behçet's disease. Clin. Rheumatol. 2008, 27:373-375.
10. Do J.E., Kwon S.Y., Park S., Lee E.S. Effects of vitamin D on expression of Toll-like receptors of monocytes from patients with Behçet's disease. Rheumatology (Oxford) 2008, 47(6):840-848.
11. Eo S.K., Kumaraguru U., Rouse B.T. Plasmid DNA encoding CCR7 ligands compensate for dysfunctional CD8+ T cell responses by effects on dendritic cells. J. Immunol. 2001, 167:3592-3599.
12. Farragher T.M., Plant D., Flynn E., Eyre S., Bunn D., Thomson W., Symmons D., Barton A. Association of a rheumatoid arthritis susceptibility variant at the CCL21 locus with premature mortality in inflammatory polyarthritis patients. Arthritis Care Res. (Hoboken) 2010, 62(5):676-682.
13. Förster R., Davalos-Misslitz A.C., Rot A. CCR7 and its ligands: balancing immunity and tolerance. Nat. Rev. Immunol. 2008, 8(5):362-371.
14. Förster R., Schubel A., Breitfeld D., Kremmer E., Renner-Muller I., Wolf E. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 1999, 99:23-33.
15. Goldrath A.W., Sivakumar P.V., Glaccum M., Kennedy M.K., Bevan M.J., Benoist C., Mathis D., Butz E.A. Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells. J. Exp. Med. 2002, 195:1515-1522.
16. Gunn M.D., Kyuwa S., Tam C., Kakiuchi T., Matsuzawa A., Williams L.T., Nakano H. Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J. Exp. Med. 1999, 189:451-460.
17. Hirata Y., Sugita T., Gyo K., Yanagihara N. Experimental vestibular neuritis induced by Herpes simplex virus. Acta. Otolaryngol. Suppl. 1993, 503:79-81.
18. Jalili A., Pashenkov M., Kriehuber E., Wagner C., Nakano H., Stingl G., Wagner S.N. Induction of targeted cell migration by cutaneous administration of a DNA vector encoding a biologically active chemokine CCL21. J. Invest. Dermatol. 2010, 130:1611-1623.
19. Jung Y.W., Rutishauser R.L., Joshi N.S., Haberman A.M., Kaech S.M. Differential localization of effector and memory CD8 T cell subsets in lymphoid organs during acute viral infection. J. Immunol. 2010, 185:5315-5325.
20. Katou F., Ohtani H., Nakayama T., Nagura H., Yoshie O., Motegi K. Differential expression of CCL19 by DC-Lamp+ mature dendritic cells in human lymph node versus chronically inflamed skin. J. Pathol. 2003, 199(1):98-106.
21. Lee E.S., Lee S., Bang D. Herpes simplex virus detection by polymerase chain reaction in intestinal ulcer of patients with Behçet's disease. Proceedings of 7th International Conference on Behçet's Disease 1997, 71-73. Pub Adhoua, Tunis. M. Hamza (Ed.).
22. Lee S., Bang D., Cho Y.H., Lee E.S., Sohn S. Polymerase chain reaction reveals herpes simplex virus DNA in saliva of patients with Behçet's disease. Arch. Dermatol. Res. 1996, 288:179-183.
23. Liu C., Ueno T., Kuse S., Saito F., Nitta T., Piali L., Nakano H., Kakiuchi T., Lipp M., Hollander G.A., Takahama Y. The role of CCL21 in recruitment of T-precursor cells to fetal thymi. Blood 2005, 105:31-39.
24. Luther S.A., Tang H.L., Hyman P.L., Farr A.G., Cyster J.G. Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse. Proc. Natl. Acad. Sci. U.S.A. 2000, 97:12694-12699.
25. Marsland B.J., Bättig P., Bauer M., Ruedl C., Lässing U., Beerli R.R., Dietmeier K., Ivanova L., Pfister T., Vogt L., Nakano H., Nembrini C., Saudan P., Kopf M., Bachmann M.F. CCL19 and CCL21 induce a potent proinflammatory differentiation program in licensed dendritic cells. Immunity 2005, 22(4):493-505.
26. Martín P., Gómez M., Lamana A., Matesanz Marín A., Cortés J.R., Ramírez-Huesca M., Barreiro O., López-Romero P., Gutiérrez-Vázquez C., de la Fuente H., Cruz-Adalia A., Sánchez-Madrid F. The leukocyte activation antigen CD69 limits allergic asthma and skin contact hypersensitivity. J. Allergy Clin. Immunol. 2010, 126(2):355-365.
27. Mullins D.W., Sheasley S.L., Ream R.M., Bullock T.N., Fu Y.X., Engelhard V.H. Route of immunization with peptide-pulsed dendritic cells controls the distribution of memory and effector T cells in lymphoid tissues and determines the pattern of regional tumor control. J. Exp. Med. 2003, 198(7):1023-1034.
28. Nakano H., Tamura T., Yoshimoto T., Yagita H., Miyasaka M., Butcher E.C., Nariuchi H., Kakiuchi T., Matsuzawa A. Genetic defect in T lymphocyte-specific homing into peripheral lymph nodes. Eur. J. Immunol. 1997, 27:215-221.
29. Pickens S.R., Chamberlain N.D., Volin M.V., Pope R.M., Talarico N.E., Mandelin A.M., Shahrara S. Role of the CCL21 and CCR7 pathway in rheumatoid arthritis angiogenesis. Arthritis Rheum. 2012 Mar 5, (Epub ahead of print). 10.1002/art.34452.
30. Prlic M., Lefrancois L., Jameson S.C. Multiple choices: regulation of memory CD8 T cell generation and homeostasis by interleukin (IL)-7 and IL-15. J. Exp. Med. 2002, 195:49-52.
31. Sallusto F., Lanzavecchia A. Understanding dendritic cell and T-lymphocyte traffic through the analysis of chemokine receptor expression. Immunol. Rev. 2000, 177:134-140.
32. Schluns K.S., Kieper W.C., Jameson S.C., Lefrancois L. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat. Immunol. 2000, 1:426-432.
33. Schluns K.S., Klonowski K.D., Lefrançois L. Transregulation of memory CD8 T-cell proliferation by IL-15Ralpha+ bone marrow-derived cells. Blood 2004, 1:988-994.
34. Shen C.H., Ge Q., Talay O., Eisen H.N., García-Sastre A., Chen J. Loss of IL-7R and IL-15R expression is associated with disappearance of memory T cells in respiratory tract following influenza infection. J. Immunol. 2008, 1:171-178.
35. Shimizu T., Ehrlich G.E., Inaba G., Hayashi K. Behcet disease (Behcet syndrome). Semin. Arthritis Rheum. 1979, 8:223-260.
36. Sohn S., Lee E.S., Kwon H.J., Lee S.I., Bang D., Lee S. Expression of Th2 cytokines decreases the development of and improves Behçet's disease-like symptoms induced by herpes simplex virus in mice. J. Infect. Dis. 2001, 183(8):1180-1186.
37. Sohn S., Bang D., Lee E.S., Kwon H.J., Lee S.I., Lee S. Experimental studies on the antiviral agent famciclovir in Behçet's disease symptoms in ICR mice. Br. J. Dermatol. 2001, 145:799-804.
38. Sohn S., Bang D., Lee S.I., Kim Y.A., Lee E.S., Ha J.Y., Kim J.H., Choi S.Y., Lee S. Combined treatment with colchicine and Herba Taraxaci (Tarazacum mongolicum Hand.-Mazz.) attenuates Behçet's disease-like symptoms in mice and influences the expressions of cytokines. Int. Immunopharmacol. 2003, 3:713-721.
39. Sohn S., Lee E.S., Bang D., Lee S. Behçet's disease-like symptoms induced by the Herpes simplex virus in ICR mice. Eur. J. Dermatol. 1998, 8:21-23.
40. Stachowiak A.N., Wang Y., Huang Y.C., Irvine D.J. Homeostatic lymphoid chemokines synergize with adhesion ligands to trigger T and B lymphocyte chemokinesis. J. Immunol. 2006, 177:2340-2348.
41. Stanford M., Whittall T., Bergmeier L.A., Lindblad M., Lundin S., Shinnick T., Mizushima Y., Holmgren J., Lehner T. Oral tolerization with peptide 336-351 linked to cholera toxin B subunit in preventing relapses of uveitis in Behçet's disease. Clin. Exp. Immunol. 2004, 137:201-208.
42. Takeuchi H., Fujimoto A., Tanaka M., Yamano T., Hsueh E., Hoon D.S. CCL21 chemokine regulates chemokine receptor CCR7 bearing malignant melanoma cells. Clin. Cancer Res. 2004, 10(7):2351-2358.
43. Ulker N., Lewis K.D., Hood L.E., Stroynowski I. Activated T cells transcribe an alternatively spliced mRNA encoding a soluble form of Qa-2 antigen. EMBO J. 1990, 9:3839-4387.
44. Vassileva G., Soto H., Zlotnik A., Nakano H., Kakiuchi T., Hedrick J.A., Lira S.A. The reduced expression of 6Ckine in the plt mouse results from the deletion of one of two 6Ckine genes. J. Exp. Med. 1999, 190:1183-1188.
45. Worbs T., Foerster R. A key role for CCR7 in establishing central and peripheral tolerance. Trends Immunol. 2007, 28:274-280.
46. Yamashita N., Tashimo H., Matsuo Y., Ishida H., Yoshiura K., Sato K., Yamashita N., Kakiuchi T., Ohta K. Role of CCL21 and CCL19 in allergic inflammation in the ovalbumin-specific murine asthmatic model. J. Allergy Clin. Immunol. 2006, 117(5):1040-1046.
47. Zlotnik A., Morales J., Hedrick J.A. Recent advances in chemokines and chemokine receptors. Crit. Rev. Immunol. 1999, 19:1-47.
48. Zlotnik A., Yoshie O. Chemokines: a new classification system and their role in immunity. Immunity 2000, 12:121-127.