Molecular mechanism of oxidation-induced TDP-43 RRM1 aggregation and loss of function

FEBS Letters

Volumn 587, Issue 6, 2013, Pages 575-582

  Chang, Chung Ke ^a   Chiang, Ming Hui ^a   Toh, Elsie Khai Woon ^a   Chang, Chi Fon ^b   Huang, Tai Huang ^a,b,c  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b GENOMICS RESEARCH CENTER   (Taiwan)

^c NATIONAL TAIWAN NORMAL UNIVERSITY   (Taiwan)

Author keywords

Neurodegenerative disease; Oxidation; Protein misfolding; RNA recognition motif; RRM1; TDP 43

Indexed keywords

BINDING PROTEIN; CYSTEINE; NUCLEIC ACID; RNA RECOGNITION MOTIF 1 PROTEIN; TAR DNA BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; MOLECULAR BIOLOGY; OXIDATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DEFECT; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION;

AMINO ACID SEQUENCE; CONSERVED SEQUENCE; CYSTEINE; DNA-BINDING PROTEINS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEURODEGENERATIVE DISEASES; OXIDATION-REDUCTION; PROTEIN DENATURATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 84875228800     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.01.038     Document Type: Article

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