1,2,3,4,6 Penta-O-galloyl-β-d-glucose, a bioactivity guided isolated compound from Mangifera indica inhibits 11β-HSD-1 and ameliorates high fat diet-induced diabetes in C57BL/6 mice

Phytomedicine

Volumn 20, Issue 5, 2013, Pages 417-426

  Mohan, C G ^a   Viswanatha, G L ^b   Savinay, G ^a   Rajendra, C E ^c   Halemani, Praveen D ^a  

^a Government College of Pharmacy   (India)

^b PES COLLEGE OF PHARMACY   (India)

^c Drug Control Department   (India)

Author keywords

1,2,3,4,6 Pentagalloyl glucose; 11 Hydroxy steroiddehydrogenase 1; Diabetes; Gallotannins; Mangifera indica; Stress

Indexed keywords

1,2,3,4,6 PENTA O GALLOYL BETA DEXTRO GLUCOSE; 11BETA HYDROXYSTEROID DEHYDROGENASE 1; ANTIDIABETIC AGENT; CARBENOXOLONE; CORTICOSTERONE; INSULIN; MANGIFERA INDICA EXTRACT; TANNIN; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DIABETES MELLITUS; DRUG ACTIVITY; DRUG SCREENING; ENZYME ACTIVITY; ENZYME INHIBITION; HYPERTRIGLYCERIDEMIA; IN VITRO STUDY; LIPID DIET; LIVER; MALE; MANGO; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PLANT LEAF; PRIORITY JOURNAL; SINGLE DRUG DOSE; SPECTROSCOPY; WEIGHT GAIN;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; ADIPOSE TISSUE, WHITE; ANIMALS; BODY WEIGHT; CARBENOXOLONE; CORTICOSTERONE; DIABETES MELLITUS, EXPERIMENTAL; DIET, HIGH-FAT; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; GLUCOSE TOLERANCE TEST; HYDROLYZABLE TANNINS; HYPOGLYCEMIC AGENTS; INSULIN; LIVER; MALE; MANGIFERA; MICE; MICE, INBRED C57BL; PHYTOTHERAPY; PLANT LEAVES;

MANGIFERA INDICA; MUS;

EID: 84875226475     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2012.12.020     Document Type: Article

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