Involvement of Src and the actin cytoskeleton in the antitumorigenic action of adenosine dialdehyde

Biochemical Pharmacology

Volumn 85, Issue 8, 2013, Pages 1042-1056

  Kim, Ji Hye ^a   Lee, Yong Gyu ^b   Yoo, Seungwan ^a   Oh, Jueun ^a   Jeong, Deok ^a   Song, Woo Keun ^c   Yoo, Byong Chul ^d   Rhee, Man Hee ^e   Park, Jongsun ^f   Cha, Sang Hoon ^b   Hong, Sungyoul ^a   Cho, Jae Youl ^a  

^a Sungkyunkwan University   (South Korea)

^b Kangwon National University   (South Korea)

^c Gwangju Institute of Science and Technology (GIST)   (South Korea)

^d National Cancer Institute   (South Korea)

^e Kyungpook National University   (South Korea)

^f Chungnam National University   (South Korea)

Author keywords

Actin cytoskeleton; Adenosine dialdehyde; S adenosylhomocysteine hydrolase; Src; Transmethylation; Tumorigenic response

Indexed keywords

3 DEAZAADENOSINE; ADENOSINE DIALDEHYDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P85; PROTEIN TYROSINE KINASE; S ADENOSYLHOMOCYSTEINE; SMALL INTERFERING RNA;

ACTIN FILAMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CARCINOGENESIS; CELL DIFFERENTIATION; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVITY; GLIOMA CELL; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAIN; UPREGULATION;

ACTIN CYTOSKELETON; ADENOSINE; ADENOSYLHOMOCYSTEINASE; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; HUMANS; METHYLATION; PHOSPHORYLATION; RATS; S-ADENOSYLHOMOCYSTEINE; SRC-FAMILY KINASES;

EID: 84875223635     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.01.012     Document Type: Article

References (62)

1. W.K. Paik, and S. Kim Protein methylation: chemical, enzymological, and biological significance Adv Enzymol Relat Areas Mol Biol 42 1975 227 286
2. S. Clarke Protein methylation Curr Opin Cell Biol 5 1993 977 983
3. C.D. Krause, Z.H. Yang, Y.S. Kim, J.H. Lee, J.R. Cook, and S. Pestka Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential Pharmacol Ther 113 2007 50 87
4. C. Balch, J.S. Montgomery, H.I. Paik, S. Kim, S. Kim, T.H. Huang, and K.P. Nephew New anti-cancer strategies: epigenetic therapies and biomarkers Front Biosci 10 2005 1897 1931
5. W.K. Paik, S. Nochumson, and S. Kim Enzymatic modification of nuclear proteins during neoplastic growth Adv Exp Med Biol 92 1977 205 232
6. S. Clarke Aging as war between chemical and biochemical processes: protein methylation and the recognition of age-damaged proteins for repair Ageing Res Rev 2 2003 263 285
7. S. Hong, J. Heo, S. Lee, S. Heo, S.S. Kim, Y.D. Lee, M. Kwon, and S. Hong Methyltransferase-inhibition interferes with neuronal differentiation of P19 embryonal carcinoma cells Biochem Biophys Res Commun 377 2008 935 940
8. B.A. Johnson, J. Najbauer, and D.W. Aswad Accumulation of substrates for protein l-isoaspartyl methyltransferase in adenosine dialdehyde-treated PC12 cells J Biol Chem 268 1993 6174 6181
9. C. Schwerk, and K. Schulze-Osthoff Methyltransferase inhibition induces p53-dependent apoptosis and a novel form of cell death Oncogene 24 2005 7002 7011
10. R.A. Klinghoffer, C. Sachsenmaier, J.A. Cooper, and P. Soriano Src family kinases are required for integrin but not PDGFR signal transduction Embo J 18 1999 2459 2471
11. C. Tsatsanis, and D.A. Spandidos The role of oncogenic kinases in human cancer (Review) Int J Mol Med 5 2000 583 590
12. E. Ingley Src family kinases: regulation of their activities, levels and identification of new pathways Biochim Biophys Acta 1784 2008 56 65
13. K. Fizazi The role of Src in prostate cancer Ann Oncol 18 2007 1765 1773
14. C.M. Silva Role of STATs as downstream signal transducers in Src family kinase-mediated tumorigenesis Oncogene 23 2004 8017 8023
15. D.L. Wheeler, M. Iida, and E.F. Dunn The role of Src in solid tumors Oncologist 14 2009 667 678
16. S. Li Src-family kinases in the development and therapy of Philadelphia chromosome-positive chronic myeloid leukemia and acute lymphoblastic leukemia Leuk Lymphoma 49 2008 19 26
17. Y.P. Chong, K.K. Ia, T.D. Mulhern, and H.C. Cheng Endogenous and synthetic inhibitors of the Src-family protein tyrosine kinases Biochim Biophys Acta 1754 2005 210 220
18. F. Hayakawa, and T. Naoe SFK-STAT pathway: an alternative and important way to malignancies Ann N Y Acad Sci 1086 2006 213 222
19. T. Nyman, H. Schuler, E. Korenbaum, C.E. Schutt, R. Karlsson, and U. Lindberg The role of MeH73 in actin polymerization and ATP hydrolysis J Mol Biol 317 2002 577 589
20. X. Yao, S. Grade, W. Wriggers, and P.A. Rubenstein His(73), often methylated, is an important structural determinant for actin. A mutagenic analysis of HIS(73) of yeast actin J. Biol. Chem. 274 1999 37443 37449
21. P. Aspenstrom Roles of F-BAR/PCH proteins in the regulation of membrane dynamics and actin reorganization Int Rev Cell Mol Biol 272 2009 1 31
22. S.E. Byeon, Y.S. Yi, J. Oh, B.C. Yoo, S. Hong, and J.Y. Cho The role of SRC kinase in macrophage-mediated inflammatory responses Mediat Inflamm 2012 2012 512926
23. P. Aspenstrom Formin-binding proteins: modulators of formin-dependent actin polymerization Biochim Biophys Acta 1803 2010 174 182
24. K.J. Yang, S. Shin, L. Piao, E. Shin, Y. Li, K.A. Park, H.S. Byun, M. Won, J. Hong, G.R. Kweon, G.M. Hur, J.H. Seok, T. Chun, D.P. Brazil, B.A. Hemmings, and J. Park Regulation of 3-phosphoinositide-dependent protein kinase-1 (PDK1) by Src involves tyrosine phosphorylation of PDK1 and Src homology 2 domain binding J Biol Chem 283 2008 1480 1491
25. M.R. Lee, B.S. Yun, L. Liu, D.L. Zhang, Z. Wang, C.L. Wang, L.J. Gu, C.Y. Wang, E.K. Mo, and C.K. Sung Effect of black ginseng on memory improvement in the amnesic mice induced by scopolamine J Ginseng Res 34 2010 51 58
26. C.O. Jeon, S.W. Kang, S.B. Park, K.T. Lim, K.W. Hwang, and H.Y. Min T cell stimulatory effects of korean red ginseng through modulation of myeloid-derived suppressor cells J Ginseng Res 35 2011 462 470
27. L. Zhao, G. Xu, J. Zhou, H. Xing, S. Wang, M. Wu, Y.P. Lu, and D. Ma The effect of RhoA on human umbilical vein endothelial cell migration and angiogenesis in vitro Oncol Rep 15 2006 1147 1152
28. J.W. Park, J.C. Lee, S. Ann, D.W. Seo, W.S. Choi, Y.H. Yoo, S.K. Park, J.Y. Choi, S.H. Um, S.H. Ahn, and J.W. Han A fermented ginseng extract, BST204 inhibits proliferation and motility of human colon cancer cells Biomol Ther 19 2011 211 217
29. S.H. Kim, S. Ahn, J.W. Han, H.W. Lee, H.Y. Lee, Y.W. Lee, M.R. Kim, K.W. Kim, W.B. Kim, and S. Hong Apicidin is a histone deacetylase inhibitor with anti-invasive and anti-angiogenic potentials Biochem Biophys Res Commun 315 2004 964 970
30. M.S. Koh, J.S. Hwang, and A. Moon Lycopene inhibits proliferation invasion and migration of human breast cancer cells Biomol Ther 18 2010 92 98
31. H.D. Yuan, S.J. Kim, H.Y. Quan, B. Huang, and S.H. Chung Ginseng leaf extract prevents high fat diet-induced hyperglycemia and hyperlipidemia through AMPK activation J Ginseng Res 34 2010 369 375
32. M.R. Lee, B.S. Yun, O.H. In, and C.K. Sung Comparative study of Korean white, red, and black ginseng extract on cholinesterase inhibitory activity and cholinergic function J Ginseng Res 35 2011 421 428
33. J.Y. Kim, Y.G. Lee, M.Y. Kim, S.E. Byeon, M.H. Rhee, J. Park, D.R. Katz, B.M. Chain, and J.Y. Cho Src-mediated regulation of inflammatory responses by actin polymerization Biochem Pharmacol 79 2010 431 443
34. H. Yang, S.E. Lee, S.I. Jeong, C.S. Park, Y.H. Jin, and Y.S. Park Up-regulation of heme oxygenase-1 by Korean red ginseng water extract as a cytoprotective effect in human endothelial cells J Ginseng Res 35 2011 352 359
35. M.K. Shim, and Y.J. Lee Estrogen receptor is activated by Korean red ginseng in vitro but not in vivo J Ginseng Res 36 2012 169 175
36. O. Dworak, L. Keilholz, and A. Hoffmann Pathological features of rectal cancer after preoperative radiochemotherapy Int J Colorectal Dis 12 1997 19 23
37. H. Do Kim, S.E. Ha, J.R. Kang, and J.K. Park Effect of Korean red ginseng extract on cell death responses in peroxynitrite-treated keratinocytes J Ginseng Res 34 2010 205 211
38. E.H. Kim, M.J. Lee, I.H. Kim, S. Pyo, K.T. Choi, and D.K. Rhee Anti-apoptotic effects of red ginseng on oxidative stress induced by hydrogen peroxide in SK-N-SH Cells J Ginseng Res 34 2010 138 144
39. K.C. Song, T.S. Chang, H. Lee, J. Kim, J.H. Park, and G.S. Hwang Processed panax ginseng. Sun ginseng increases type I collagen by regulating MMP-1 and TIMP-1 expression in human dermal fibroblasts J Ginseng Res 36 2012 61 67
40. A. Dasgupta, K.J. Jung, S.J. Jeong, and J.N. Brady Inhibition of methyltransferases results in induction of g2/m checkpoint and programmed cell death in human T-lymphotropic virus type 1-transformed cells J Virol 82 2008 49 59
41. B. Bostrom, H.P. Hogenkamp, and B.L. Mirkin Inhibitory effect of adenosine dialdehyde on in situ murine neuroblastoma growth Cancer Res 48 1988 5933 5936
42. B. Bauvois New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: outside-in signaling and relationship to tumor progression Biochim Biophys Acta 1825 2012 29 36
43. H.C. Cheng, T.M. Johnson, R.D. Mills, Y.P. Chong, K.C. Chan, and J.G. Culvenor Allosteric networks governing regulation and catalysis of Src-family protein tyrosine kinases: implications for disease-associated kinases Clin Exp Pharmacol Physiol 37 2010 93 101
44. M.J. Smolinska, T.H. Page, A.M. Urbaniak, B.E. Mutch, and N.J. Horwood Hck tyrosine kinase regulates TLR4-induced TNF and IL-6 production via AP-1 J Immunol 187 2011 6043 6051
45. J. Ryu, J. Song, J. Heo, Y. Jung, S.J. Lee, S. Hong, and J.Y. Cho Cross-regulation between protein L-isoaspartyl O-methyltransferase and ERK in epithelial mesenchymal transition of MDA-MB-231 cells Acta Pharmacol Sin 32 2011 1165 1172
46. C.M. Park, M.J. Park, H.J. Kwak, H.C. Lee, M.S. Kim, S.H. Lee, I.C. Park, C.H. Rhee, and S.I. Hong Ionizing radiation enhances matrix metalloproteinase-2 secretion and invasion of glioma cells through Src/epidermal growth factor receptor-mediated p38/Akt and phosphatidylinositol 3-kinase/Akt signaling pathways Cancer Res 66 2006 8511 8519
47. M.R. Bubb, A.M. Senderowicz, E.A. Sausville, K.L. Duncan, E.D. Korn, and Jasplakinolide A cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin J Biol Chem 269 1994 14869 14871
48. R.M. Pascale, M.M. Simile, M.R. De Miglio, and F. Feo Chemoprevention of hepatocarcinogenesis: S-adenosyl-l-methionine Alcohol 27 2002 193 198
49. D. Stautz, A. Sanjay, M.T. Hansen, R. Albrechtsen, U.M. Wewer, and M. Kveiborg ADAM12 localizes with c-Src to actin-rich structures at the cell periphery and regulates Src kinase activity Exp Cell Res 316 2010 55 67
50. J.M. Bujnicki, S.T. Prigge, D. Caridha, and P.K. Chiang Structure, evolution, and inhibitor interaction of S-adenosyl-l-homocysteine hydrolase from Plasmodium falciparum Proteins 52 2003 624 632
51. R.L. Bartel, and R.T. Borchardt Effects of adenosine dialdehyde on S-adenosylhomocysteine hydrolase and S-adenosylmethionine-dependent transmethylations in mouse L929 cells Mol Pharmacol 25 1984 418 424
52. R.S. Finn Targeting Src in breast cancer Ann Oncol: Off J Eur Soc Med Oncol/ESMO 19 2008 1379 1386
53. S. Hiscox, and R.I. Nicholson Src inhibitors in breast cancer therapy Expert Opin Ther Targets 12 2008 757 767
54. J. Xu, M. Millard, X. Ren, O.T. Cox, and A. Erdreich-Epstein c-Abl mediates endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 and by disruption of actin Blood 115 2010 2709 2718
55. Y. Tajika, T. Matsuzaki, T. Suzuki, A. Ablimit, T. Aoki, H. Hagiwara, M. Kuwahara, S. Sasaki, and K. Takata Differential regulation of AQP2 trafficking in endosomes by microtubules and actin filaments Histochem Cell Biol 124 2005 1 12
56. C.E. Turner Paxillin interactions J Cell Sci 23 2000 4139 4140 113 Pt
57. A. Stenzinger, D. Schreiner, P. Koch, H.W. Hofer, and M. Wimmer Cell and molecular biology of the novel protein tyrosine-phosphatase-interacting protein 51 Int Rev Cell Mol Biol 275 2009 183 246
58. T. Matozaki, Y. Murata, M. Mori, T. Kotani, H. Okazawa, and H. Ohnishi Expression, localization, and biological function of the R3 subtype of receptor-type protein tyrosine phosphatases in mammals Cell Signal 22 2010 1811 1817
59. T. Baba, N. Fusaki, N. Shinya, A. Iwamatsu, and N. Hozumi Actin tyrosine dephosphorylation by the Src homology 1-containing protein tyrosine phosphatase is essential for actin depolymerization after membrane IgM cross-linking J Immunol 170 2003 3762 3768
60. C. Vijayasarathy, and B.S. Rao Partial purification and characterisation of S-adenosylmethionine:protein-histidine N-methyltransferase from rabbit skeletal muscle Biochim Biophys Acta 923 1987 156 165
61. K.J. Webb, C.I. Zurita-Lopez, Q. Al-Hadid, A. Laganowsky, B.D. Young, R.S. Lipson, P. Souda, K.F. Faull, J.P. Whitelegge, and S.G. Clarke A novel 3-methylhistidine modification of yeast ribosomal protein Rpl3 is dependent upon the YIL110W methyltransferase J Biol Chem 285 2010 37598 37606
62. L.N. Puls, M. Eadens, and W. Messersmith Current status of SRC inhibitors in solid tumor malignancies Oncologist 16 2011 566 578