Interleukin-6 modulates oxidative stress produced during the development of cisplatin nephrotoxicity

Life Sciences

Volumn 92, Issue 12, 2013, Pages 694-700

  Mitazaki, Satoru ^a   Hashimoto, Midori ^a   Matsuhashi, Yui ^a   Honma, Shigeyoshi ^a   Suto, Miwako ^b   Kato, Naho ^b   Nakagawasai, Osamu ^c   Tan No, Koichi ^c   Hiraiwa, Kouichi ^b   Yoshida, Makoto ^a   Abe, Sumiko ^a  

^a TAKASAKI UNIVERSITY OF HEALTH AND WELFARE   (Japan)

^b FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^c TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Cisplatin; Dimethylthiourea; HO 1; Hydroxyl radical; IL 6; Nrf2

Indexed keywords

CISPLATIN; DIMETHYLTHIOUREA; HEME OXYGENASE 1; INTERLEUKIN 6; PROTEIN BAX; PROTEIN BCL XL; PROTEIN C FOS; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; GENE EXPRESSION; KIDNEY DYSFUNCTION; KIDNEY FUNCTION; KIDNEY PARENCHYMA; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RENAL PROTECTION; SURVIVAL RATE; UPREGULATION;

ACUTE KIDNEY INJURY; ANIMALS; ANTINEOPLASTIC AGENTS; CISPLATIN; FREE RADICAL SCAVENGERS; GENE EXPRESSION REGULATION; GENE KNOCKOUT TECHNIQUES; HEME OXYGENASE-1; INTERLEUKIN-6; KIDNEY; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; THIOUREA;

MUS;

EID: 84875218844     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2013.01.026     Document Type: Article

References (31)

1. B.B. Aggarwal, A.B. Kunnumakkara, K.B. Harikumar, S.R. Gupta, S.T. Tharakan, and C. Koca Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship? Ann N Y Acad Sci 1171 2009 59 76
2. R.S. Al-Lamki, W. Lu, S. Finlay, J.P. Twohig, E.C. Wang, and A.M. Tolkovsky DR3 signaling protects against cisplatin nephrotoxicity mediated by tumor necrosis factor Am J Pathol 180 2012 1454 1464
3. I. Arany, and R.L. Safirstein Cisplatin nephrotoxicity Semin Nephrol 23 2003 460 464
4. I. Arany, A. Faisal, J.S. Clark, T. Vera, R. Baliga, and Y. Nagamine p66SHC-mediated mitochondrial dysfunction in renal proximal tubule cells during oxidative injury Am J Physiol Renal Physiol 298 2010 F1214 F1221
5. R. Baliga, Z. Zhang, M. Baliga, N. Ueda, and S.V. Shah In vitro and in vivo evidence suggesting a role for iron in cisplatin-induced nephrotoxicity Kidney Int 53 1998 394 401
6. R. Baliga, N. Ueda, P.D. Walker, and S.V. Shah Oxidant mechanisms in toxic acute renal failure Drug Metab Rev 31 1999 971 997
7. S. Bolisetty, A.M. Traylor, J. Kim, R. Joseph, K. Ricart, and A. Landar Heme oxygenase-1 inhibits renal tubular macroautophagy in acute kidney injury J Am Soc Nephrol 21 2010 1702 1712
8. H.Y. Cho, A.E. Jedlicka, S.P. Reddy, T.W. Kensler, M. Yamamoto, and L.Y. Zhang Role of NRF2 in protection against hyperoxic lung injury in mice Am J Respir Cell Mol Biol 26 2002 175 182
9. S. Dhakshinamoorthy, D.J. Long 2nd, and A.K. Jaiswal Antioxidant regulation of genes encoding enzymes that detoxify xenobiotics and carcinogens Curr Top Cell Regul 36 2000 201 216
10. P. Duann, and E.A. Lianos GEC-targeted HO-1 expression reduces proteinuria in glomerular immune injury Am J Physiol Renal Physiol 297 2009 F629 F638
11. M.A. Fuertes, J. Castilla, C. Alonso, and J.M. Perez Cisplatin biochemical mechanism of action: from cytotoxicity to induction of cell death through interconnections between apoptotic and necrotic pathways Curr Med Chem 10 2003 257 266
12. C. Gabay Interleukin-6 and chronic inflammation Arthritis Res Ther 8 Suppl. 2 2006 S3
13. A.K. Jaiswal Nrf2 signaling in coordinated activation of antioxidant gene expression Free Radic Biol Med 36 2004 1199 1207
14. M. Jiang, Q. Wei, N. Pabla, G. Dong, C.Y. Wang, and T. Yang Effects of hydroxyl radical scavenging on cisplatin-induced p53 activation, tubular cell apoptosis and nephrotoxicity Biochem Pharmacol 73 2007 1499 1510
15. C. Klein, T. Wustefeld, U. Assmus, T. Roskams, S. Rose-John, and M. Muller The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury J Clin Invest 115 2005 860 869
16. K. Kobayashi, J. Kuroda, N. Shibata, T. Hasegawa, Y. Seko, and M. Satoh Induction of metallothionein by manganese is completely dependent on interleukin-6 production J Pharmacol Exp Ther 320 2007 721 727
17. T. Koyama, S. Kume, D. Koya, S. Araki, K. Isshiki, and M. Chin-Kanasaki SIRT3 attenuates palmitate-induced ROS production and inflammation in proximal tubular cells Free Radic Biol Med 51 2011 1258 1267
18. J. Liu, M.L. Cheng, Q. Yang, K.R. Shan, J. Shen, and Y. Zhou Blood metallothionein transcript as a biomarker for metal sensitivity: low blood metallothionein transcripts in arsenicosis patients from Guizhou, China Environ Health Perspect 115 2007 1101 1106
19. S. Mitazaki, N. Kato, M. Suto, K. Hiraiwa, and S. Abe Interleukin-6 deficiency accelerates cisplatin-induced acute renal failure but not systemic injury Toxicology 265 2009 115 121
20. S. Mitazaki, S. Honma, M. Suto, N. Kato, K. Hiraiwa, and M. Yoshida Interleukin-6 plays a protective role in development of cisplatin-induced acute renal failure through upregulation of anti-oxidative stress factors Life Sci 88 2011 1142 1148
21. W. Plum, D.F. Tschaharganeh, D.C. Kroy, E. Corsten, S. Erschfeld, and U. Dierssen Lack of glycoprotein 130/signal transducer and activator of transcription 3-mediated signaling in hepatocytes enhances chronic liver injury and fibrosis progression in a model of sclerosing cholangitis Am J Pathol 176 2010 2236 2246
22. N.A. Santos, C.S. Bezerra, N.M. Martins, C. Curti, M.L. Bianchi, and A.C. Santos Hydroxyl radical scavenger ameliorates cisplatin-induced nephrotoxicity by preventing oxidative stress, redox state unbalance, impairment of energetic metabolism and apoptosis in rat kidney mitochondria Cancer Chemother Pharmacol 61 2008 145 155
23. Z.H. Siddik Cisplatin: mode of cytotoxic action and molecular basis of resistance Oncogene 22 2003 7265 7279
24. T. Taguchi, A. Nazneen, M.R. Abid, and M.S. Razzaque Cisplatin-associated nephrotoxicity and pathological events Contrib Nephrol 148 2005 107 121
25. K. Tanabe, R. Matsushima-Nishiwaki, S. Yamaguchi, H. Iida, S. Dohi, and O. Kozawa Mechanisms of tumor necrosis factor-alpha-induced interleukin-6 synthesis in glioma cells J Neuroinflammation 7 2010 16
26. K. Tsuruya, T. Ninomiya, M. Tokumoto, M. Hirakawa, K. Masutani, and M. Taniguchi Direct involvement of the receptor-mediated apoptotic pathways in cisplatin-induced renal tubular cell death Kidney Int 63 2003 72 82
27. K. Tsuruya, M. Tokumoto, T. Ninomiya, M. Hirakawa, K. Masutani, and M. Taniguchi Antioxidant ameliorates cisplatin-induced renal tubular cell death through inhibition of death receptor-mediated pathways Am J Physiol Renal Physiol 285 2003 F208 F218
28. R. Venugopal, and A.K. Jaiswal Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes Oncogene 17 1998 3145 3156
29. A.B. Waxman, and N. Kolliputi IL-6 protects against hyperoxia-induced mitochondrial damage via Bcl-2-induced Bak interactions with mitofusins Am J Respir Cell Mol Biol 41 2009 385 396
30. C.J. Wruck, K. Streetz, G. Pavic, M.E. Gotz, M. Tohidnezhad, and L.O. Brandenburg Nrf2 induces interleukin-6 (IL-6) expression via an antioxidant response element within the IL-6 promoter J Biol Chem 286 2011 4493 4499
31. S.H. Wu, C. Lu, L. Dong, G.P. Zhou, Z.G. He, and Z.Q. Chen Lipoxin A4 inhibits TNF-alpha-induced production of interleukins and proliferation of rat mesangial cells Kidney Int 68 2005 35 46