-
1
-
-
84858429240
-
Endogenous viruses: Insights into viral evolution and impact on host biology
-
Feschotte, C. & Gilbert, C. Endogenous viruses: insights into viral evolution and impact on host biology. Nat. Rev. Genet. 13, 283-296 (2012).
-
(2012)
Nat. Rev. Genet
, vol.13
, pp. 283-296
-
-
Feschotte, C.1
Gilbert, C.2
-
2
-
-
77954100084
-
Transposable elements have rewired the core regulatory network of human embryonic stem cells
-
Kunarso, G. et al. Transposable elements have rewired the core regulatory network of human embryonic stem cells. Nat. Genet. 42, 631-634 (2010).
-
(2010)
Nat. Genet
, vol.42
, pp. 631-634
-
-
Kunarso, G.1
-
3
-
-
80055010534
-
Transposon-mediated rewiring of gene regulatory networks contributed to the evolution of pregnancy in mammals
-
Lynch, V.J., Leclerc, R.D., May, G. & Wagner, G.P. Transposon-mediated rewiring of gene regulatory networks contributed to the evolution of pregnancy in mammals. Nat. Genet. 43, 1154-1159 (2011).
-
(2011)
Nat. Genet
, vol.43
, pp. 1154-1159
-
-
Lynch, V.J.1
Leclerc, R.D.2
May, G.3
Wagner, G.P.4
-
4
-
-
67349170854
-
Embryonic stem cells use ZFP809 to silence retroviral DNAs
-
Wolf, D. & Goff, S.P. Embryonic stem cells use ZFP809 to silence retroviral DNAs. Nature 458, 1201-1204 (2009).
-
(2009)
Nature
, vol.458
, pp. 1201-1204
-
-
Wolf, D.1
Goff, S.P.2
-
5
-
-
74549116659
-
KAP1 controls endogenous retroviruses in embryonic stem cells
-
Rowe, H.M. et al. KAP1 controls endogenous retroviruses in embryonic stem cells. Nature 463, 237-240 (2010).
-
(2010)
Nature
, vol.463
, pp. 237-240
-
-
Rowe, H.M.1
-
6
-
-
79951669703
-
Tripartite-motif proteins and innate immune regulation
-
McNab, F.W., Rajsbaum, R., Stoye, J.P. & O'Garra, A. Tripartite-motif proteins and innate immune regulation. Curr. Opin. Immunol. 23, 46-56 (2011).
-
(2011)
Curr. Opin. Immunol
, vol.23
, pp. 46-56
-
-
McNab, F.W.1
Rajsbaum, R.2
Stoye, J.P.3
O'Garra, A.4
-
7
-
-
27244444559
-
TRIM family proteins: Retroviral restriction and antiviral defence
-
Nisole, S., Stoye, J.P. & Saib, A. TRIM family proteins: retroviral restriction and antiviral defence. Nat. Rev. Microbiol. 3, 799-808 (2005).
-
(2005)
Nat. Rev. Microbiol
, vol.3
, pp. 799-808
-
-
Nisole, S.1
Stoye, J.P.2
Saib, A.3
-
8
-
-
80052289447
-
Regulation of innate immune signalling pathways by the tripartite motif (TRIM) family proteins
-
Kawai, T. & Akira, S. Regulation of innate immune signalling pathways by the tripartite motif (TRIM) family proteins. EMBO Mol. Med. 3, 513-527 (2011).
-
(2011)
EMBO Mol. Med
, vol.3
, pp. 513-527
-
-
Kawai, T.1
Akira, S.2
-
9
-
-
80052971797
-
The TIF1α-related TRIM cofactors couple chromatin modifications to transcriptional regulation, signaling and tumor suppression
-
Herquel, B., Ouararhni, K. & Davidson, I. The TIF1α-related TRIM cofactors couple chromatin modifications to transcriptional regulation, signaling and tumor suppression. Transcription 2, 231-236 (2011).
-
(2011)
Transcription
, vol.2
, pp. 231-236
-
-
Herquel, B.1
Ouararhni, K.2
Davidson, I.3
-
10
-
-
78650353481
-
TRIM24 links a non-canonical histone signature to breast cancer
-
Tsai, W.W. et al. TRIM24 links a non-canonical histone signature to breast cancer. Nature 468, 927-932 (2010).
-
(2010)
Nature
, vol.468
, pp. 927-932
-
-
Tsai, W.W.1
-
11
-
-
79959891289
-
Recruitment of TIF1γ to chromatin via Its PHD finger-bromodomain activates its ubiquitin ligase and transcriptional repressor activities
-
Agricola, E., Randall, R.A., Gaarenstroom, T., Dupont, S. & Hill, C.S. Recruitment of TIF1γ to chromatin via Its PHD finger-bromodomain activates its ubiquitin ligase and transcriptional repressor activities. Mol. Cell 43, 85-96 (2011).
-
(2011)
Mol. Cell
, vol.43
, pp. 85-96
-
-
Agricola, E.1
Randall, R.A.2
Gaarenstroom, T.3
Dupont, S.4
Hill, C.S.5
-
12
-
-
36549086517
-
Loss of Trim24 (Tif1α) gene function confers oncogenic activity to retinoic acid receptor alpha
-
Khetchoumian, K. et al. Loss of Trim24 (Tif1α) gene function confers oncogenic activity to retinoic acid receptor alpha. Nat. Genet. 39, 1500-1506 (2007).
-
(2007)
Nat. Genet
, vol.39
, pp. 1500-1506
-
-
Khetchoumian, K.1
-
13
-
-
57349132931
-
Trim24 (Tif1α): An essential 'brake' for retinoic acid-induced transcription to prevent liver cancer
-
Khetchoumian, K. et al. Trim24 (Tif1α): an essential 'brake' for retinoic acid-induced transcription to prevent liver cancer. Cell Cycle 7, 3647-3652 (2008).
-
(2008)
Cell Cycle
, vol.7
, pp. 3647-3652
-
-
Khetchoumian, K.1
-
14
-
-
79957738075
-
Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma
-
Herquel, B. et al. Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma. Proc. Natl. Acad. Sci. USA 108, 8212-8217 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 8212-8217
-
-
Herquel, B.1
-
15
-
-
0030960513
-
Structure and functional properties of mouse VL30 retrotransposons
-
French, N.S. & Norton, J.D. Structure and functional properties of mouse VL30 retrotransposons. Biochim. Biophys. Acta 1352, 33-47 (1997).
-
(1997)
Biochim. Biophys. Acta
, vol.1352
, pp. 33-47
-
-
French, N.S.1
Norton, J.D.2
-
16
-
-
0027979259
-
Inducible and cell type-specific expression of VL30 U3 subgroups correlate with their enhancer design
-
Nilsson, M. & Bohm, S. Inducible and cell type-specific expression of VL30 U3 subgroups correlate with their enhancer design. J. Virol. 68, 276-288 (1994).
-
(1994)
J. Virol
, vol.68
, pp. 276-288
-
-
Nilsson, M.1
Bohm, S.2
-
17
-
-
80053023388
-
Tripartite motif 24 (Trim24/Tif1α) tumor suppressor protein is a novel negative regulator of interferon (IFN)/signal transducers and activators of transcription (STAT) signaling pathway acting through retinoic acid receptor α (Rarα) inhibition
-
Tisserand, J. et al. Tripartite motif 24 (Trim24/Tif1α) tumor suppressor protein is a novel negative regulator of interferon (IFN)/signal transducers and activators of transcription (STAT) signaling pathway acting through retinoic acid receptor α (Rarα) inhibition. J. Biol. Chem. 286, 33369-33379 (2011).
-
(2011)
J. Biol. Chem
, vol.286
, pp. 33369-33379
-
-
Tisserand, J.1
-
18
-
-
49549122469
-
Linking retroelements to autoimmunity
-
Bhoj, V.G. & Chen, Z.J. Linking retroelements to autoimmunity. Cell 134, 569-571 (2008).
-
(2008)
Cell
, vol.134
, pp. 569-571
-
-
Bhoj, V.G.1
Chen, Z.J.2
-
19
-
-
49549100511
-
Trex1 prevents cell-intrinsic initiation of autoimmunity
-
Stetson, D.B., Ko, J.S., Heidmann, T. & Medzhitov, R. Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell 134, 587-598 (2008).
-
(2008)
Cell
, vol.134
, pp. 587-598
-
-
Stetson, D.B.1
Ko, J.S.2
Heidmann, T.3
Medzhitov, R.4
-
20
-
-
0028098771
-
Nuclear orphan receptor-binding retinoic acid response elements in keratinocytes
-
Islam, T.C. & Toftgard, R. Nuclear orphan receptor-binding retinoic acid response elements in keratinocytes. Biochem. Biophys. Res. Commun. 203, 545-552 (1994).
-
(1994)
Biochem. Biophys. Res. Commun
, vol.203
, pp. 545-552
-
-
Islam, T.C.1
Toftgard, R.2
-
21
-
-
84855695113
-
Transcription factor TEAD4 regulates expression of Myogenin and the unfolded protein response genes during C2C12 cell differentiation
-
Benhaddou, A. et al. Transcription factor TEAD4 regulates expression of Myogenin and the unfolded protein response genes during C2C12 cell differentiation. Cell Death Differ. 19, 220-231 (2012).
-
(2012)
Cell Death Differ
, vol.19
, pp. 220-231
-
-
Benhaddou, A.1
-
22
-
-
77952367798
-
Widespread transcription at neuronal activity-regulated enhancers
-
Kim, T.K. et al. Widespread transcription at neuronal activity-regulated enhancers. Nature 465, 182-187 (2010).
-
(2010)
Nature
, vol.465
, pp. 182-187
-
-
Kim, T.K.1
-
23
-
-
84862778066
-
Intragenic enhancers act as alternative promoters
-
Kowalczyk, M.S. et al. Intragenic enhancers act as alternative promoters. Mol. Cell 45, 447-458 (2012).
-
(2012)
Mol. Cell
, vol.45
, pp. 447-458
-
-
Kowalczyk, M.S.1
-
24
-
-
79961022267
-
Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters
-
Koch, F. et al. Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters. Nat. Struct. Mol. Biol. 18, 956-963 (2011).
-
(2011)
Nat. Struct. Mol. Biol
, vol.18
, pp. 956-963
-
-
Koch, F.1
-
25
-
-
79551655285
-
Functional and mechanistic diversity of distal transcription enhancers
-
Bulger, M. & Groudine, M. Functional and mechanistic diversity of distal transcription enhancers. Cell 144, 327-339 (2011).
-
(2011)
Cell
, vol.144
, pp. 327-339
-
-
Bulger, M.1
Groudine, M.2
-
26
-
-
0027460080
-
The long terminal repeat of VL30 retrotransposons contains sequences that determine retinoic acid-induced transcription in cultured keratinocytes
-
Islam, T.C., Bugge, T.H. & Bohm, S. The long terminal repeat of VL30 retrotransposons contains sequences that determine retinoic acid-induced transcription in cultured keratinocytes. J. Biol. Chem. 268, 3251-3259 (1993).
-
(1993)
J. Biol. Chem
, vol.268
, pp. 3251-3259
-
-
Islam, T.C.1
Bugge, T.H.2
Bohm, S.3
-
27
-
-
77952411179
-
Epigenetic regulation of a murine retrotransposon by a dual histone modification mark
-
Brunmeir, R. et al. Epigenetic regulation of a murine retrotransposon by a dual histone modification mark. PLoS Genet. 6, e1000927 (2010).
-
(2010)
PLoS Genet
, vol.6
-
-
Brunmeir, R.1
-
28
-
-
0033571206
-
Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family
-
Nielsen, A.L. et al. Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family. EMBO J. 18, 6385-6395 (1999).
-
(1999)
EMBO J
, vol.18
, pp. 6385-6395
-
-
Nielsen, A.L.1
-
29
-
-
77950400643
-
Aicardi-Goutieres syndrome and related phenotypes: Linking nucleic acid metabolism with autoimmunity
-
Crow, Y.J. & Rehwinkel, J. Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity. Hum. Mol. Genet. 18, R130-R136 (2009).
-
(2009)
Hum. Mol. Genet
, vol.18
-
-
Crow, Y.J.1
Rehwinkel, J.2
-
30
-
-
80054848955
-
TRIM proteins and cancer
-
Hatakeyama, S. TRIM proteins and cancer. Nat. Rev. Cancer 11, 792-804 (2011).
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 792-804
-
-
Hatakeyama, S.1
-
31
-
-
84856429876
-
Obesity, inflammation, and liver cancer
-
Sun, B. & Karin, M. Obesity, inflammation, and liver cancer. J. Hepatol. 56, 704-713 (2012).
-
(2012)
J. Hepatol
, vol.56
, pp. 704-713
-
-
Sun, B.1
Karin, M.2
-
32
-
-
84856394989
-
Chronic inflammation and hepatocellular carcinoma
-
Alison, M.R., Nicholson, L.J. & Lin, W.R. Chronic inflammation and hepatocellular carcinoma. Recent Results Cancer Res. 185, 135-148 (2011).
-
(2011)
Recent Results Cancer Res
, vol.185
, pp. 135-148
-
-
Alison, M.R.1
Nicholson, L.J.2
Lin, W.R.3
-
33
-
-
33746522835
-
Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutieres syndrome and mimic congenital viral brain infection
-
Crow, Y.J. et al. Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutieres syndrome and mimic congenital viral brain infection. Nat. Genet. 38, 910-916 (2006).
-
(2006)
Nat. Genet
, vol.38
, pp. 910-916
-
-
Crow, Y.J.1
-
34
-
-
33746581694
-
Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus
-
Crow, Y.J. et al. Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus. Nat. Genet. 38, 917-920 (2006).
-
(2006)
Nat. Genet
, vol.38
, pp. 917-920
-
-
Crow, Y.J.1
-
35
-
-
77957243921
-
Long noncoding RNAs with enhancer-like function in human cells
-
Ørom, U.A. et al. Long noncoding RNAs with enhancer-like function in human cells. Cell 143, 46-58 (2010).
-
(2010)
Cell
, vol.143
, pp. 46-58
-
-
Ørom, U.A.1
-
37
-
-
33746423865
-
Locus control region transcription plays an active role in long-range gene activation
-
Ho, Y., Elefant, F., Liebhaber, S.A. & Cooke, N.E. Locus control region transcription plays an active role in long-range gene activation. Mol. Cell 23, 365-375 (2006).
-
(2006)
Mol. Cell
, vol.23
, pp. 365-375
-
-
Ho, Y.1
Elefant, F.2
Liebhaber, S.A.3
Cooke, N.E.4
-
38
-
-
77952908743
-
A large fraction of extragenic RNA pol II transcription sites overlap enhancers
-
De Santa, F. et al. A large fraction of extragenic RNA pol II transcription sites overlap enhancers. PLoS Biol. 8, e1000384 (2010).
-
(2010)
PLoS Biol
, vol.8
-
-
De Santa, F.1
-
39
-
-
65449136284
-
TopHat: Discovering splice junctions with RNA-Seq
-
Trapnell, C., Pachter, L. & Salzberg, S.L. TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 25, 1105-1111 (2009).
-
(2009)
Bioinformatics
, vol.25
, pp. 1105-1111
-
-
Trapnell, C.1
Pachter, L.2
Salzberg, S.L.3
-
40
-
-
77952123055
-
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
-
Trapnell, C. et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat. Biotechnol. 28, 511-515 (2010).
-
(2010)
Nat. Biotechnol
, vol.28
, pp. 511-515
-
-
Trapnell, C.1
-
41
-
-
77958471357
-
Differential expression analysis for sequence count data
-
Anders, S. & Huber, W. Differential expression analysis for sequence count data. Genome Biol. 11, R106 (2010).
-
(2010)
Genome Biol
, vol.11
-
-
Anders, S.1
Huber, W.2
-
42
-
-
84857840693
-
Interconversion between active and inactive TATA-binding protein transcription complexes in the mouse genome
-
Choukrallah, M.A. et al. Interconversion between active and inactive TATA-binding protein transcription complexes in the mouse genome. Nucleic Acids Res. 40, 1446-1459 (2012).
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 1446-1459
-
-
Choukrallah, M.A.1
-
43
-
-
79953699973
-
SeqMINER: An integrated ChIP-seq data interpretation platform
-
Ye, T. et al. seqMINER: an integrated ChIP-seq data interpretation platform. Nucleic Acids Res. 39, e35 (2011).
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Ye, T.1
|