Molecular mechanism of anti-inflammatory activity of Pluchea indica leaves in macrophages RAW 264.7 and its action in animal models ofinflammation

Journal of Ethnopharmacology

Volumn 146, Issue 2, 2013, Pages 495-504

  Buapool, Doungnapa ^a   Mongkol, Nadtaya ^b   Chantimal, Jirapa ^a   Roytrakul, Sittiruk ^c   Srisook, Ekaruth ^a   Srisook, Kloakwan ^a  

^a BURAPHA UNIVERSITY   (Thailand)

^b Mahidol University ^*  (Thailand)

^c NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY   (Thailand)

Author keywords

Anti inflammatory; Asteraceae; Carrageenan; Inducible nitric oxide synthase; Nitric oxide; PGE2; Pluchea indica

Indexed keywords

ACETIC ACID ETHYL ESTER; ANTIINFLAMMATORY AGENT; CARRAGEENAN; DICLOFENAC; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; NITRITE; PHENYLBUTAZONE; PLANT EXTRACT; PLUCHEA INDICA EXTRACT; PROSTAGLANDIN E2; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTERACEAE; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EAR EDEMA; ENZYME PHOSPHORYLATION; GENE EXPRESSION; IN VIVO STUDY; INFLAMMATION; MACROPHAGE; MALE; NONHUMAN; PAW EDEMA; PLANT LEAF; PLUCHEA INDICA; PROMOTER REGION; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ALKYNES; ANIMALS; ANTI-INFLAMMATORY AGENTS; ASTERACEAE; CARRAGEENAN; CELL LINE; CELL SURVIVAL; DINOPROSTONE; DISEASE MODELS, ANIMAL; EDEMA; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

ANIMALIA; ASTERACEAE; PLUCHEA INDICA; RATTUS;

EID: 84875208836     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.01.014     Document Type: Article

References (48)

1. W.K. Alderton, C.E. Cooper, and R.G. Knowles Nitric oxide synthases: structure, function and inhibition Biochemical Journal 357 2001 593 615 (Pubitemid 32735142)
2. R. Biswas, P.K. Dutta, B. Achari, D. Bandyopadhyay, M. Mishra, K.C. Pramanik, and T.K. Chatterjee Isolation of pure compound R/J/3 from Pluchea indica (L.) Less. and its anti-amoebic activities against Entamoeba histolytica Phytomedicine 143 2007 534 537 (Pubitemid 47068949)
3. R. Brattsand, A. Thalen, K. Roempke, L. Kallstrom, and E. Gruvstad Influence of 16α, 17α-acetal substitution and steroid nucleus fluorination on the topical to systemic activity ratio of glucocorticoids Journal of Steroid Biochemistry 16 1982 779 786 (Pubitemid 13228092)
4. A.B. Carter, K.L. Knudtson, M.M. Monick, and G.W. Hunninghake The p38 mitogen activated protein kinase is required for NF-κB-dependent gene expression. The role of TATA-binding protein (TBP). Journal of Biological Chemistry 274 1999 30858 30863
5. D. Chaturvedi Sesquiterpene lactones: structural diversity and their biological activities V.K. Tiwari, Opportunity, Challenge and Scope of Natural Products in Medicinal Chemistry 2011 Research Signpost Kerala 313 334
6. A.K. Chakravarty, and S. Mukhopadhyay New thiophene derivatives from Pluchea indica Indian Journal of Chemistry 33 1994 978 980
7. B.C. Chen, Y.H. Chen, and W.W. Lin Involvement of p38 mitogen-activated protein kinase in lipopolysaccharide-induced iNOS and COX-2 expression in J774 macrophage Immunology 97 1999 124 129
8. X. Cheng, Q. Zeng, J. Ren, J. Qin, S. Zhang, Y. Shen, J. Zhu, F. Zhang, R. Chang, Y. Zhu, W. Zhang, and H. Jin Sesquiterpene lactones from Inula falconeri, a plant endemic to the Himalayas, as potential anti-inflammatory agents European Journal of Medicinal Chemistry 46 2011 5408 5415
9. M.S. Cheon, T. Yoon, D.Y. Lee, G. Choi, B.C. Moon, A.Y. Lee, B.K. Choo, and H.K. Kim Chrysanthemum indicum Linne extract inhibits the inflammatory response by suppressing NF-κB and MAPKs activation in lipopolysaccharide- induced RAW 264.7 macrophage Journal of Ethnopharmacology 122 2009 473 477
10. M.E. Choi, and K.J. Hwang Screening of Indonesian medicinal plants for inhibitor activity on nitric oxide production of RAW 264.7 cells and antioxidant activity Fitoterapia 76 2005 194 203
11. M.A. Dorheim, W.R. Tracey, J.S. Pollock, and P. Grammas Nitric oxide synthase activity is elevated in brain microvessels in Alzheimer's disease Biochemical and Biophysical Research Communication 205 1994 659 665 (Pubitemid 24381677)
12. V. Garcia-Mediavilla, I. Crespo, P.S. Collado, A. Esteller, S.S. Campos, M.J. Tunon, and J.G. Gallego The anti-inflammatory flavones quercetin and kaempferol cause inhibition of indicible nitric oxide synthase, cyclooxygenase-2 and reactive C-protein, and down-regulation of the nuclear factor kappaB pathway in Chang Liver cells European Journal of Pharmacology 557 2007 221 229 (Pubitemid 46186282)
13. T.J. Guzik, R. Korbut, and T. Adamek-Guzik Nitric oxide and superoxide in inflammation and immune regulation Journal of Physiology and Pharmacology 54 2003 469 487 (Pubitemid 38029745)
14. J.W. Hartley, L.H. Evans, K.Y. Green, Z. Naghashfar, A.R. Macias, P.M. Zerfas, and J.M. Ward Expression of infectious murine leukemia viruses by RAW264.7 cells, a potential complication for studies with a widely used mouse macrophage cell line Retrovirology 5 2008 1 6
15. Y.C. Hseu, F.Y. Wu, J.J. Wu, J.Y. Chen, W.H. Chang, F.J. Lu, Y.C. Lai, and H.L. Yang Anti-inflammatory potential of Antrodia camphorata through inhibition of iNOS, COX-2 and cytokines via the NF-κB pathway International Immunology 5 2005 1914 1925
16. D.A. Israf, T.A. Khaizurin, A. Syahida, N.H. Lajis, and S. Khozirah Cardamonin inhibits COX and iNOS expression via inhibition of p65NF-κB nuclear translocation and I-κB phosphorylation in RAW264.7 macrophage cells Molecular Immunology 44 2007 673 679 (Pubitemid 44415023)
17. S.H. Kim, J. Kim, and R.P. Sharma Inhibition of p38 and ERK MAP kinases blocks endotoxin-induced nitric oxide production and differentially modulates cytokine expression Pharmacological Research 49 2004 433 439 (Pubitemid 38283863)
18. S.H. Kim, and T.Y. Shin Anti-inflammatory effect of leaves of Eriobotrya japonica correlating with attenuation of p38 MAPK, ERK, and NF-κB activation in mast cells Toxicology In Vitro 23 2009 1215 1219
19. Y.H. Kim, J.Y. Han, J.H. Sung, M.S. Sung, Y.M. Choi, H.S. Jeong, and J.S. Lee Anti-inflammatory activity of Chrysanthemum zawadskii var. latilobum leaf extract through haem oxygenase-1 induction Journal of Functional Foods 4 2012 474 479
20. V. Kumar, A.K. Abbas, N. Fausto, and R.N. Mitchell Robbins Basic Pathology eight ed. 2007 Elsevier Saunders, United States of America
21. K.A. Latham, K.B. Whittington, R. Zhou, Z. Qian, and E.F. Rosloniec Ex vivo characterization of the autoimmune T cell response in the HLA-DR1 mouse model of collagen-induced arthritis reveals long-term activation of type II collagen-specific cells and their presence in arthritic joints Journal of Immunology 174 2005 3978 3985 (Pubitemid 40395972)
22. M.Y. Lee, J.A. Lee, C.S. Seo, H. Ha, H. Lee, J.K. Son, and H.K. Shin Anti-inflammatory activity of Angelica dahurica ethanolic extract on RAW24.7 cells via upregulation of heme oxygenase-1 Food and Chemical Toxicology 49 2011 1047 1055
23. H.Y. Lin, S.H. Juan, S.C. Shen, F.L. Hsu, and Y.C. Chen Inhibition of lipopolysaccharide-induced nitric oxide production by flavonoids in RAW264.7 macrophages involves heme oxygenase-1 Biochemical Pharmacology 66 2003 1821 1832
24. Lowenstein, C.J., Alley, E.W., Raval, P., Snowman, A.M., Snyder, S.H., Russell, S.W., Murphy, W.J., 1993. Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide. Proceedings of the National Academy of Sciences of the United States of America. 90, 9730-9734. (Pubitemid 23315860)
25. W. Mequanint, E. Makonnen, and K. Urga In vivo anti-inflammatory activities of leaf extracts of Ocimum lamiifolium in mice model Journal of Ethnopharmacology 134 2011 32 36
26. C.J. Morris Carrageenan-induced paw edema in the rat and mouse Method in Molecular Biology 225 2003 115 121
27. S. Mukhopadhyay, A.G. Cordell, N. Ruangrungsi, S. Rodkird, P. Tantivatana, and P.J. Hylands Traditional medicanal plants of Thailand. IV. 3-(2′,3′-Diacetoxy-2′-methyl butyryl)-cuauhtehmone from Pluchea indica Journal of Natural Products 46 1983 671 674 (Pubitemid 14214941)
28. H. Nakano, M. Shindo, S. Sakon, S. Nishinaka, M. Mihara, H. Yagita, and K. Okumura Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-κB inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1 Proceedings of the National Academy of Sciences of the United States of America 95 1998 3537 3542
29. A.R. Noridayu, H.F. Hii, A. Faridah, S. Khozirah, and N. Lajis Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less. International Food Research Journal 18 2011 925 929
30. Office of Mangrove Resources Conservation Department of Marine and Coastal Resources, Ministry of Natural Resources and Environment 2009 Plants in the Mangrove forest of Thailand. Printing House of the Agricultural Co-operative Federation of Thailand Limited Nonthaburi, (in Thai)
31. T. Ohtsuki, E. Yokosawa, T. Koyano, S. Preeprame, T. Kowithayakorn, S. Sakai, T. Toida, and M. Ishibashi Quinic acid esters from Pluchea indica with collagenase, MMP-2 and MMP-9 inhibitory activities Phytotherapy Research 22 2008 264 266 (Pubitemid 351363251)
32. A. Panthong, W. Supraditaporn, D. Kanjanapothi, T. Taesotikul, and V. Reutrakul Analgesic, anti- inflammatory and venotonic effects of Cissus quadrangularis Linn Journal of Ethnopharmacology 110 2007 264 270 (Pubitemid 46283661)
33. A.H. Roslida, A.K. Erazuliana, and A. Zuraini Anti-inflammatory and antinociceptive activities of the ethanolic extract of Pluchea indica (L)Less leaf Pharmacologyonline 2 2008 349 360
34. C. Sae-Wong, P. Tansakul, and S. Tewtrakul Anti-inflammatory mechanism of Kaempferia parviflora in murine macrophage cell (RAW264.7) and in experimental animals Journal of Ethnopharmacology 124 2009 576 580
35. D. Salvemini, Z.Q. Wang, P.S. Wyatt, D.M. Bourdon, M.H. Marino, P.T. Manning, and M.G. Currie Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation British Journal of Pharmacology 118 1996 829 838 (Pubitemid 26261251)
36. M.A.M. Shukri, C. Alan, and A.R.S. Noorzuraini Polyphenols and antioxidant activities of selected traditional vegetables Journal of Tropical Agriculture and Food Science 39 2011 1 15
37. T. Sen, A.K. Dhara, S. Bhattacharjee, S. Pal, and A.K. Chaudhuri Antioxidant activity of the methanol fraction of Pluchea indica root extract Phytotherapy Research 16 2002 331 335 (Pubitemid 34700270)
38. T. Sen, T.K. Ghosh, and A.K. Nag Chaudhuri Studies on the mechanism of anti-inflammatory and anti-ulcer activity of Pluchea indica-probable involvement of 5-lipoxygenase pathway Life Sciences 52 1993 737 743
39. K. Srisook, D. Buapool, R. Boonbai, P. Simmasut, Y. Charoensuk, and E. Srisook Antioxidant and anti-inflammatory activities of hot water extract from Pluchea indica Less herbal tea Journal of Medicinal Plants Research 6 2012 4077 4081
40. K. Srisook, and Y.N. Cha Superinduction of heme oxygenase-1 in macrophages stimulated with lipopolysaccharide by prior depletion of glutathione decreases iNOS expression and NO production Nitric Oxide: Biology and Chemistry 12 2005 70 79 (Pubitemid 40312448)
41. K. Srisook, M. Palachot, N. Mongkol, E. Srisook, and S. Sarapusit Anti-inflammatory effect of ethyl acetate extract from Cissus quadrangularis Linn may be involved with induction of heme oxygenase-1 and suppression of NF-κB activation Journal of Ethnopharmacology 133 2011 1008 1014
42. T. Uchiyama, T. Miyase, A. Ueno, and K. Usmanghani Terpenic glycosides from Pluchea indica Phytochemistry 28 1989 3369 3372
43. Y. Uchiyama, T. Miyase, A. Ueno, and K. Usmanghani Terpene and lignan glycosides from Pluchea indica Phytochemistry 30 1991 655 657
44. D.A. Valério, T.M. Cunha, N.S. Arakawa, H.P. Lemos, F.B. Da Costa, C.A. Parada, S.H. Ferreira, F.Q. Cunha, and W.A. Verri Jr. Anti-inflammatory and analgesic effects of the sesquiterpene lactone budlein A in mice: inhibition of cytokine production-dependent mechanism European Journal Pharmacology 562 2007 155 163 (Pubitemid 46466751)
45. C.A. Winter, E.A. Risley, and G.W. Nuss Carrageenin-induced edema in hind paw of the rat as an assay for anti-inflammatory drug Proceedings of the Society for Experimental Biology and Medicine 111 1962 544 547
46. C.E. Wright, D.D. Rees, and S. Moncada Protective and pathological roles of nitric oxide in endotoxin shock Cardiovascular Research 26 1992 48 57
47. Q.X. Wu, Y.P. Shi, and Z.J. Jia Eudesmane sesquiterpenoids from the Asteraceae family Natural Product Reports 23 2006 699 734
48. H. Yang, D.W. Young, F. Gusovsky, and J.C. Chow Cellular events mediated by lipopolysaccharide-stimulated toll-like receptor 4 Journal of Biological Chemistry 27 2000 20861 20866