Antiplatelet therapy and the outcome of subjects with intracranial injury: The Italian SIMEU study

Critical Care

Volumn 17, Issue 2, 2013, Pages

  Fabbri, Andrea ^a   Servadei, Franco ^b   Marchesini, Giulio ^c   Bronzoni, Carolina ^b   Montesi, Danilo ^c   Arietta, Luca ^c  

^a MORGAGNI PIERANTONI HOSPITAL   (Italy)

^b UNIVERSITY HOSPITAL OF PARMA   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; LOW MOLECULAR WEIGHT HEPARIN; TICLOPIDINE; WARFARIN; ANTITHROMBOCYTIC AGENT;

ADULT; AGE; AGED; ANTICOAGULANT THERAPY; ARTICLE; BRAIN CONTUSION; BRAIN HEMORRHAGE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; EMERGENCY CARE; FEMALE; GLASGOW OUTCOME SCALE; HEAD INJURY; HUMAN; ITALY; MAJOR CLINICAL STUDY; MALE; NEUROIMAGING; PREDICTION; PRIORITY JOURNAL; TREATMENT DURATION; TREATMENT OUTCOME; CLINICAL TRIAL; CRANIOCEREBRAL TRAUMA; FOLLOW UP; MIDDLE AGED; MULTICENTER STUDY; TRENDS; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; CRANIOCEREBRAL TRAUMA; FEMALE; FOLLOW-UP STUDIES; GLASGOW OUTCOME SCALE; HUMANS; ITALY; MALE; MIDDLE AGED; PLATELET AGGREGATION INHIBITORS; TREATMENT OUTCOME;

EID: 84875202520     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc12575     Document Type: Article

References (42)

1. Fabbri A, Servadei F, Marchesini G, Stein SC, Vandelli A. Observational approach to subjects with mild-to-moderate head injury and initial non-neurosurgical lesions. J Neurol Neurosurg Psychiatry 2008, 79:1180-1185. 10.1136/jnnp.2007.135178, 18356255.
2. Fabbri A, Servadei F, Marchesini G, Stein SC, Vandelli A. Early predictors of unfavourable outcome in subjects with moderate head injury in the emergency department. J Neurol Neurosurg Psychiatry 2008, 79:567-573. 10.1136/jnnp.2007.120162, 17766433.
3. Chang EF, Meeker M, Holland MC. Acute traumatic intraparenchymal hemorrhage: risk factors for progression in the early post-injury period. Neurosurgery 2006, 58:647-656. discussion 647-656, 10.1227/01.NEU.0000197101.68538.E6, 16575328.
4. Chieregato A, Fainardi E, Morselli-Labate AM, Antonelli V, Compagnone C, Targa L, Kraus J, Servadei F. Factors associated with neurological outcome and lesion progression in traumatic subarachnoid hemorrhage patients. Neurosurgery 2005, 56:671-680. discussion 671-680, 10.1227/01.NEU.0000156200.76331.7A, 15792505.
5. Smith SC, Blair SN, Bonow RO, Brass LM, Cerqueira MD, Dracup K, Fuster V, Gotto A, Grundy SM, Miller NH, Jacobs A, Jones D, Krauss RM, Mosca L, Ockene I, Pasternak RC, Pearson T, Pfeffer MA, Starke RD, Taubert KA. AHA/ACC Scientific Statement: AHA/ACC guidelines for preventing heart attack and death in patients with atherosclerotic cardiovascular disease: 2001 update: a statement for healthcare professionals from the American Heart Association and the American College of Cardiology. Circulation 2001, 104:1577-1579. 10.1161/hc3801.097475, 11571256.
6. Patrono C, Bachmann F, Baigent C, Bode C, De Caterina R, Charbonnier B, Fitzgerald D, Hirsh J, Husted S, Kvasnicka J, Montalescot G, García Rodríguez LA, Verheugt F, Vermylen J, Wallentin L, Priori SG, Alonso Garcia MA, Blanc JJ, Budaj A, Cowie M, Dean V, Deckers J, Fernández Burgos E, Lekakis J, Lindahl B, Mazzotta G, Morais J, Oto A, Smiseth OA, Morais J, Deckers J, et al. Expert consensus document on the use of antiplatelet agents. The task force on the use of antiplatelet agents in patients with atherosclerotic cardiovascular disease of the European society of cardiology. Eur Heart J 2004, 25:166-181. 10.1016/j.ehj.2003.10.013, 14720534.
7. Giannoudis PV, Harwood PJ, Court-Brown C, Pape HC. Severe and multiple trauma in older patients: incidence and mortality. Injury 2009, 40:362-367. 10.1016/j.injury.2008.10.016, 19217104.
8. O'Donnell MJ, Xavier D, Liu L, Zhang H, Chin SL, Rao-Melacini P, Rangarajan S, Islam S, Pais P, McQueen MJ, Mondo C, Damasceno A, Lopez-Jaramillo P, Hankey GJ, Dans AL, Yusoff K, Truelsen T, Diener HC, Sacco RL, Ryglewicz D, Czlonkowska A, Weimar C, Wang X, Yusuf S, INTERSTROKE investigators Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study. Lancet 2012, 376:112-123. INTERSTROKE investigators.
9. Martini SR, Flaherty ML, Brown WM, Haverbusch M, Comeau ME, Sauerbeck LR, Kissela BM, Deka R, Kleindorfer DO, Moomaw CJ, Broderick JP, Langefeld CD, Woo D. Risk factors for intracerebral hemorrhage differ according to hemorrhage location. Neurology 2012, 79:2275-2282. 10.1212/WNL.0b013e318276896f, 23175721.
10. Marshall LF, Marshall SB, Klauber MR, Van Berkum Clark M. A new classification of head injury based on computerized tomography. J Neurosurg 1991, 75:S14-S20.
11. Servadei F, Murray GD, Teasdale GM, Dearden M, Iannotti F, Lapierre F, Maas AJ, Karimi A, Ohman J, Persson L, Stocchetti N, Trojanowski T, Unterberg A. Traumatic subarachnoid hemorrhage: demographic and clinical study of 750 patients from the European brain injury consortium survey of head injuries. Neurosurgery 2002, 50:261-267. discussion 267-269.
12. Fabbri A, Servadei F, Marchesini G, Morselli-Labate AM, Dente M, Iervese T, Spada M, Vandelli A. Prospective validation of a proposal for diagnosis and management of patients attending the emergency department for mild head injury. J Neurol Neurosurg Psychiatry 2004, 75:410-416. 10.1136/jnnp.2003.016113, 1738984, 14966157.
13. Stiell IG, Wells GA, Vandemheen K, Clement C, Lesiuk H, Laupacis A, McKnight RD, Verbeek R, Brison R, Cass D, Eisenhauer ME, Greenberg G, Worthington J. The Canadian CT Head Rule for patients with minor head injury. Lancet 2001, 357:1391-1396. 10.1016/S0140-6736(00)04561-X, 11356436.
14. Pang-Ning Tan MS, Vipin K. Introduction to Data Mining. Pearson Education, Upper Saddle River Publisher, NJ (US). 2006, 1-769.
15. Kurland D, Hong C, Aarabi B, Gerzanich V, Simard JM. Hemorrhagic progression of a contusion after traumatic brain injury: a review. J Neurotrauma 2012, 29:19-31. 10.1089/neu.2011.2122, 3253310, 21988198.
16. Smith JS, Chang EF, Rosenthal G, Meeker M, von Koch C, Manley GT, Holland MC. The role of early follow-up computed tomography imaging in the management of traumatic brain injury patients with intracranial hemorrhage. J Trauma 2007, 63:75-82. 10.1097/01.ta.0000245991.42871.87, 17622872.
17. Hukkelhoven CW, Steyerberg EW, Habbema JD, Farace E, Marmarou A, Murray GD, Marshall LF, Maas AI. Predicting outcome after traumatic brain injury: development and validation of a prognostic score based on admission characteristics. J Neurotrauma 2005, 22:1025-1039. 10.1089/neu.2005.22.1025, 16238481.
18. Maas AI, Steyerberg EW, Butcher I, Dammers R, Lu J, Marmarou A, Mushkudiani NA, McHugh GS, Murray GD. Prognostic value of computerized tomography scan characteristics in traumatic brain injury: results from the IMPACT study. J Neurotrauma 2007, 24:303-314. 10.1089/neu.2006.0033, 17375995.
19. Steyerberg EW, Mushkudiani N, Perel P, Butcher I, Lu J, McHugh GS, Murray GD, Marmarou A, Roberts I, Habbema JD, Maas AI. Predicting outcome after traumatic brain injury: development and international validation of prognostic scores based on admission characteristics. PLoS Med 2008, 5:e165. discussion e165, 10.1371/journal.pmed.0050165, 2494563, 18684008.
20. Servadei F, Murray GD, Penny K, Teasdale GM, Dearden M, Iannotti F, Lapierre F, Maas AJ, Karimi A, Ohman J, Persson L, Stocchetti N, Trojanowski T, Unterberg A. The value of the "worst" computed tomographic scan in clinical studies of moderate and severe head injury. European Brain Injury Consortium. Neurosurgery 2000, 46:70-75. discussion 75-77.
21. Alahmadi H, Vachhrajani S, Cusimano MD. The natural history of brain contusion: an analysis of radiological and clinical progression. J Neurosurg 2010, 112:1139-1145. 10.3171/2009.5.JNS081369, 19575576.
22. Oertel M, Kelly DF, McArthur D, Boscardin WJ, Glenn TC, Lee JH, Gravori T, Obukhov D, McBride DQ, Martin NA. Progressive hemorrhage after head trauma: predictors and consequences of the evolving injury. J Neurosurg 2002, 96:109-116. 10.3171/jns.2002.96.1.0109, 11794591.
23. Stein SC, Spettell C, Young G, Ross SE. Delayed and progressive brain injury in closed-head trauma: radiological demonstration. Neurosurgery 1993, 32:25-30. discussion 30-21, 10.1227/00006123-199301000-00004, 8421553.
24. Narayan RK, Maas AI, Servadei F, Skolnick BE, Tillinger MN, Marshall LF. Progression of traumatic intracerebral hemorrhage: a prospective observational study. J Neurotrauma 2008, 25:629-639. 10.1089/neu.2007.0385, 18491950.
25. Flint AC, Manley GT, Gean AD, Hemphill JC, Rosenthal G. Post-operative expansion of hemorrhagic contusions after unilateral decompressive hemicraniectomy in severe traumatic brain injury. J Neurotrauma 2008, 25:503-512. 10.1089/neu.2007.0442, 18346002.
26. Yadav YR, Basoor A, Jain G, Nelson A. Expanding traumatic intracerebral contusion/hematoma. Neurol India 2006, 54:377-381. 10.4103/0028-3886.28109, 17114846.
27. Hamm CW, Bassand JP, Agewall S, Bax J, Boersma E, Bueno H, Caso P, Dudek D, Gielen S, Huber K, Ohman M, Petrie MC, Sonntag F, Uva MS, Storey RF, Wijns W, Zahger D, , Bax JJ, Auricchio A, Baumgartner H, Ceconi C, Dean V, Deaton C, Fagard R, Funck-Brentano C, Hasdai D, Hoes A, Knuuti J, Kolh P, et al. ESC Committee for Practice Guidelines ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: the task force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J 2011, 32:2999-3054. ESC Committee for Practice Guidelines.
28. Wijns W, Kolh P, Danchin N, Di Mario C, Falk V, Folliguet T, Garg S, Huber K, James S, Knuuti J, Lopez-Sendon J, Marco J, Menicanti L, Ostojic M, Piepoli MF, Pirlet C, Pomar JL, Reifart N, Ribichini FL, Schalij MJ, Sergeant P, Serruys PW, Silber S, Sousa Uva M, Taggart D. Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS); European Association for Percutaneous Cardiovascular Interventions (EAPCI) Guidelines on myocardial revascularization. Eur Heart J 2010, 31:2501-2555. Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS); European Association for Percutaneous Cardiovascular Interventions (EAPCI).
29. De Rosa M, Marchesini G. Osservatorio ARNO diabete. Analisi di 10 anni di prescrizioni. Collana Rapporti ARNO 2007, XI:1-47. Bologna: CINECA, Consorzio interuniversitario.
30. Osservatorio Nazionale sull'impiego dei medicinali L'uso dei Farmaci in Italia. 2008, 36. In Roma: ISS-AIFA, Osservatorio Nazionale sull'impiego dei medicinali.
31. Beynon C, Hertle DN, Unterberg AW, Sakowitz OW. Clinical review: traumatic brain injury in patients receiving antiplatelet medication. Crit Care 2012, 16:228.
32. Batchelor JS, Grayson A. A meta-analysis to determine the effect of anticoagulation on mortality in patients with blunt head trauma. Br J Neurosurg 2012, 26:525-530. 10.3109/02688697.2011.650736, 22324438.
33. Spektor S, Agus S, Merkin V, Constantini S. Low-dose aspirin prophylaxis and risk of intracranial hemorrhage in patients older than 60 years of age with mild or moderate head injury: a prospective study. J Neurosurg 2003, 99:661-665. 10.3171/jns.2003.99.4.0661, 14567600.
34. Fabbri A, Servadei F, Marchesini G, Stein SC, Vandelli A. Predicting intracranial lesions by antiplatelet agents in subjects with mild head injury. J Neurol Neurosurg Psychiatry 81:1275-1279.
35. Ivascu FA, Howells GA, Junn FS, Bair HA, Bendick PJ, Janczyk RJ. Predictors of mortality in trauma patients with intracranial hemorrhage on preinjury aspirin or clopidogrel. J Trauma 2008, 65:785-788. 10.1097/TA.0b013e3181848caa, 18849791.
36. Patel HC, Bouamra O, Woodford M, King AT, Yates DW, Lecky FE. Trends in head injury outcome from 1989 to 2003 and the effect of neurosurgical care: an observational study. Lancet 2005, 366:1538-1544. 10.1016/S0140-6736(05)67626-X, 16257340.
37. Servadei F, Antonelli V, Mastrilli A, Cultrera F, Giuffrida M, Staffa G. Integration of image transmission into a protocol for head injury management: a preliminary report. Br J Neurosurg 2002, 16:36-42. 10.1080/02688690120114255, 11926463.
38. Visca A, Faccani G, Massaro F, Bosio D, Ducati A, Cogoni M, Kraus J, Servadei F. Clinical and neuroimaging features of severely brain-injured patients treated in a neurosurgical unit compared with patients treated in peripheral non-neurosurgical hospitals. Br J Neurosurg 2006, 20:82-86. 10.1080/02688690600682416, 16753622.
39. Donze J, Clair C, Hug B, Rodondi N, Waeber G, Cornuz J, Aujesky D. Risk of falls and major bleeds in patients on oral anticoagulation therapy. Am J Med 2012, 125:773-778. 10.1016/j.amjmed.2012.01.033, 22840664.
40. Gasparyan AY, Watson T, Lip GY. The role of aspirin in cardiovascular prevention: implications of aspirin resistance. J Am Coll Cardiol 2008, 51:1829-1843. 10.1016/j.jacc.2007.11.080, 18466797.
41. Greer DM. Aspirin and antiplatelet agent resistance: implications for prevention of secondary stroke. CNS Drugs 2010, 24:1027-1040. 10.2165/11539160-0000000000-00000, 20932071.
42. Bachelani AM, Bautz JT, Sperry JL, Corcos A, Zenati M, Billiar TR, Peitzman AB, Marshall GT. Assessment of platelet transfusion for reversal of aspirin after traumatic brain injury. Surgery 2011, 150:836-843. 10.1016/j.surg.2011.07.059, 22000198.