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Volumn 24, Issue 12, 2010, Pages 1027-1040

Aspirin and antiplatelet agent resistance: Implications for prevention of secondary stroke

Author keywords

Antiplatelets, therapeutic use; Aspirin, therapeutic use; Clopidogrel, therapeutic use; Dipyridamole, therapeutic use; Prasugrel, therapeutic use; Stroke

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; CLOPIDOGREL; DIPYRIDAMOLE; PRASUGREL; THROMBOXANE B2;

EID: 78649338758     PISSN: 11727047     EISSN: 11791934     Source Type: Journal    
DOI: 10.2165/11539160-0000000000-00000     Document Type: Review
Times cited : (20)

References (86)
  • 1
    • 4644289299 scopus 로고    scopus 로고
    • Platelet-active drugs: The relationships among dose, effectiveness, and side effects
    • The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy Sep
    • Patrono C, Coller B, FitzGerald GA, et al. Platelet-active drugs: the relationships among dose, effectiveness, and side effects. The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 2004 Sep; 126 (3 Suppl.): 234S-64S
    • (2004) Chest , vol.126 , Issue.3 SUPPL.
    • Patrono, C.1    Coller, B.2    Fitzgerald, G.A.3
  • 2
    • 44449107747 scopus 로고    scopus 로고
    • Update to the AHA/ASA recommendations for the prevention of stroke in patients with stroke and transient ischemic attack
    • May
    • Adams RJ, Albers G, Alberts MJ, et al. Update to the AHA/ASA recommendations for the prevention of stroke in patients with stroke and transient ischemic attack. Stroke 2008 May; 39: 1-6
    • (2008) Stroke , vol.39 , pp. 1-6
    • Adams, R.J.1    Albers, G.2    Alberts, M.J.3
  • 3
    • 0037065502 scopus 로고    scopus 로고
    • Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients
    • Antithrombotic Trialists' Collaboration Jan
    • Antithrombotic Trialists' Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 2002 Jan; 324: 71-86
    • (2002) BMJ , vol.324 , pp. 71-86
  • 4
    • 5444220166 scopus 로고    scopus 로고
    • Oral antiplatelet therapy in cerebrovas- cular disease, coronary artery disease, and peripheral arterial disease
    • Oct
    • Tran H, Anand SS. Oral antiplatelet therapy in cerebrovas- cular disease, coronary artery disease, and peripheral arterial disease. JAMA 2004 Oct; 292: 1867-74
    • (2004) JAMA , vol.292 , pp. 1867-74
    • Tran, H.1    Anand, S.S.2
  • 5
    • 34547760330 scopus 로고    scopus 로고
    • A com- parison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery disease
    • Jul
    • Lordkipanidze M, Pharand C, Schampaert E, et al. A com- parison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery disease. Eur Heart J 2007 Jul; 28: 1702-8
    • (2007) Eur Heart J , vol.28 , pp. 1702-8
    • Lordkipanidze, M.1    Pharand, C.2    Schampaert, E.3
  • 6
    • 3042537320 scopus 로고    scopus 로고
    • The antithrom- botic profile of aspirin: Aspirin resistance or simply failure?
    • Jan [online]. Available from URL Accessed 2010 Sep 13
    • Altman R, Luciardi HL, Muntaner J, et al. The antithrom- botic profile of aspirin: aspirin resistance or simply failure? Thromb J 2004 Jan; 2: 1 [online]. Available from URL: http://www.thrombosisjournal.com/content/2/1/1 [Accessed 2010 Sep 13]
    • (2004) Thromb J , vol.2 , Issue.1
    • Altman, R.1    Luciardi, H.L.2    Muntaner, J.3
  • 7
    • 0000073434 scopus 로고    scopus 로고
    • Internal analgesic, antipyretic, and antirheumatic drug products for over-the-counter human use: Final rule for professional labeling of aspirin, buffered aspirin, and aspirin in combination with antacid drug products
    • U.S. Food and Drug Administration
    • U.S. Food and Drug Administration. Internal analgesic, antipyretic, and antirheumatic drug products for over-the-counter human use: final rule for professional labeling of aspirin, buffered aspirin, and aspirin in combination with antacid drug products. Fed Regist 1998; 63: 56802-19
    • (1998) Fed Regist , vol.63 , pp. 56802-19
  • 8
    • 4644261801 scopus 로고    scopus 로고
    • Antithrombotic and thrombolytic therapy for ischemic stroke: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    • Sep
    • Albers GW, Amarenco P, Easton JD, et al. Antithrombotic and thrombolytic therapy for ischemic stroke: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 2004 Sep; 126 (3 Suppl.): 483S-512S
    • (2004) Chest , vol.126 , Issue.3 SUPPL.
    • Albers, G.W.1    Amarenco, P.2    Easton, J.D.3
  • 9
    • 0026072561 scopus 로고
    • A comparison of two doses of aspirin (30mg vs. 283mg a day) in patients after a transient ischemic attack or minor ischemic stroke
    • Dutch TIA Trial Study Group Oct
    • Dutch TIA Trial Study Group. A comparison of two doses of aspirin (30mg vs. 283mg a day) in patients after a transient ischemic attack or minor ischemic stroke. N Engl J Med 1991 Oct; 325: 1261-6
    • (1991) N Engl J Med , vol.325 , pp. 1261-6
  • 10
    • 34248352504 scopus 로고    scopus 로고
    • Aspirin dose for the prevention of cardiovascular disease: A systematic review
    • May
    • Campbell CL, Smyth S, Montalescot G, et al. Aspirin dose for the prevention of cardiovascular disease: a systematic review. JAMA 2007 May; 297: 2018-24
    • (2007) JAMA , vol.297 , pp. 2018-24
    • Campbell, C.L.1    Smyth, S.2    Montalescot, G.3
  • 11
    • 3242770664 scopus 로고    scopus 로고
    • Aspirin and clopidogrel compared with clopido-grel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): Randomised, double-blind, placebo-controlled trial
    • MATCH In- vestigators Jul
    • Diener HC, Bogousslavsky J, Brass LM, et al., MATCH In- vestigators. Aspirin and clopidogrel compared with clopido-grel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial. Lancet 2004 Jul; 364: 331-7
    • (2004) Lancet , vol.364 , pp. 331-7
    • Diener, H.C.1    Bogousslavsky, J.2    Brass, L.M.3
  • 12
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators Aug
    • Yusuf S, Zhao F, Mehta SR, et al., Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001 Aug; 345: 494-502
    • (2001) N Engl J Med , vol.345 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3
  • 13
    • 33645861080 scopus 로고    scopus 로고
    • Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events
    • CHARISMA Investi- gators Apr
    • Bhatt DL, Fox KA, Hacke W, et al., CHARISMA Investi- gators. Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N Engl J Med 2006 Apr; 354: 1706-17
    • (2006) N Engl J Med , vol.354 , pp. 1706-17
    • Bhatt, D.L.1    Fox, K.A.2    Hacke, W.3
  • 14
    • 43949140550 scopus 로고    scopus 로고
    • Response to pharmacodynamic interaction between aspirin and ibu-profen: A plausible mechanism of aspirin resistance
    • Jun
    • Patrignani P, Renda G, Tacconelli S, et al. Response to pharmacodynamic interaction between aspirin and ibu-profen: a plausible mechanism of aspirin resistance. Clin Pharmacol Ther 2008 Jun; 83: 812-3
    • (2008) Clin Pharmacol Ther , vol.83 , pp. 812-3
    • Patrignani, P.1    Renda, G.2    Tacconelli, S.3
  • 15
    • 34250164286 scopus 로고    scopus 로고
    • Aspirin esterase activity: Evidence for skewed distribution in healthy volunteers
    • Jul
    • Adebayo GI, Williams J, Healy S. Aspirin esterase activity: evidence for skewed distribution in healthy volunteers. Eur J Intern Med 2007 Jul; 18: 299-303
    • (2007) Eur J Intern Med , vol.18 , pp. 299-303
    • Adebayo, G.I.1    Williams, J.2    Healy, S.3
  • 16
    • 33644614033 scopus 로고    scopus 로고
    • Increased blood plasma hydrolysis of acetylsalicylic acid in type 2 diabetic patients: A role of plasma esterases
    • Feb
    • Gresner P, Doln?k M, Waczul?kova I, et al. Increased blood plasma hydrolysis of acetylsalicylic acid in type 2 diabetic patients: a role of plasma esterases. Biochim Biophys Acta 2006 Feb; 1760: 207-15
    • (2006) Biochim Biophys Acta , vol.1760 , pp. 207-15
    • Gresner, P.1    Dolnk, M.2    Waczulkova, I.3
  • 17
    • 64649091484 scopus 로고    scopus 로고
    • Aspirin noncompliance is the major cause of "aspirin resistance" in patients undergoing coronary stenting
    • May
    • Cuisset T, Frere C, Quilici J, et al. Aspirin noncompliance is the major cause of "aspirin resistance" in patients undergoing coronary stenting. Am Heart J 2009 May; 157 (5): 889-93
    • (2009) Am Heart J , vol.157 , Issue.5 , pp. 889-93
    • Cuisset, T.1    Frere, C.2    Quilici, J.3
  • 18
    • 0037261957 scopus 로고    scopus 로고
    • Adherence to secondary stroke prevention strategies: Results from the German Stroke Data Bank
    • German Stroke Data Bank
    • Hamann GF, Weimar C, Glahn J, et al., German Stroke Data Bank. Adherence to secondary stroke prevention strategies: results from the German Stroke Data Bank. Cerebrovasc Dis 2003; 15 (4): 282-8
    • (2003) Cerebrovasc Dis , vol.15 , Issue.4 , pp. 282-8
    • Hamann, G.F.1    Weimar, C.2    Glahn, J.3
  • 20
    • 0035924765 scopus 로고    scopus 로고
    • Cyclooxy- genase inhibitors and the antiplatelet effects of aspirin
    • Dec 20
    • Catella-Lawson F, Reilly MP, Kapoor SC, et al. Cyclooxy- genase inhibitors and the antiplatelet effects of aspirin. N Engl J Med 2001 Dec 20; 345 (25): 1809-17
    • (2001) N Engl J Med , vol.345 , Issue.25 , pp. 1809-17
    • Catella-Lawson, F.1    Reilly, M.P.2    Kapoor, S.C.3
  • 21
    • 33747168513 scopus 로고    scopus 로고
    • Effect of enteric coating on antiplatelet activity of low-dose aspirin in healthy volunteers
    • Aug
    • Cox D, Maree AO, Dooley M, et al. Effect of enteric coating on antiplatelet activity of low-dose aspirin in healthy volunteers. Stroke 2006 Aug; 37 (8): 2153-8
    • (2006) Stroke , vol.37 , Issue.8 , pp. 2153-8
    • Cox, D.1    Maree, A.O.2    Dooley, M.3
  • 22
    • 33646098899 scopus 로고    scopus 로고
    • Lack of effect of enteric coating on aspirin-induced inhibition of platelet aggregation in healthy volunteers
    • May
    • Karha J, Rajagopal V, Kottke-Marchant K, et al. Lack of effect of enteric coating on aspirin-induced inhibition of platelet aggregation in healthy volunteers. Am Heart J 2006 May; 151: 976.e7-e11
    • (2006) Am Heart J , vol.151
    • Karha, J.1    Rajagopal, V.2    Kottke-Marchant, K.3
  • 23
    • 34247574729 scopus 로고    scopus 로고
    • Reticulated platelets and uninhibited COX-1 and COX-2 decrease the antiplatelet effects of aspirin
    • Mar
    • Guthikonda S, Lev EI, Patel R, et al. Reticulated platelets and uninhibited COX-1 and COX-2 decrease the antiplatelet effects of aspirin. J Thromb Haemost 2007 Mar; 5: 490-6
    • (2007) J Thromb Haemost , vol.5 , pp. 490-6
    • Guthikonda, S.1    Lev, E.I.2    Patel, R.3
  • 24
    • 1442299043 scopus 로고    scopus 로고
    • Aspirin resistance
    • Feb
    • Hankey GJ, Eikelboom JW. Aspirin resistance. BMJ 2004 Feb; 328: 477-9
    • (2004) BMJ , vol.328 , pp. 477-9
    • Hankey, G.J.1    Eikelboom, J.W.2
  • 25
    • 34247897084 scopus 로고    scopus 로고
    • Relationship between en- dothelial dysfunction, oxidant stress and aspirin resistance in patients with stable coronary heart disease
    • Jun
    • Cheng G, Shan J, Xu G, et al. Relationship between en- dothelial dysfunction, oxidant stress and aspirin resistance in patients with stable coronary heart disease. J Clin Pharm Ther 2007 Jun; 32: 287-92
    • (2007) J Clin Pharm Ther , vol.32 , pp. 287-92
    • Cheng, G.1    Shan, J.2    Xu, G.3
  • 26
    • 47249143688 scopus 로고    scopus 로고
    • Pharmacogenetics of aspi- rin resistance: A comprehensive systematic review
    • Aug
    • Goodman T, Ferro A, Sharma P. Pharmacogenetics of aspi- rin resistance: a comprehensive systematic review. Br J Clin Pharmacol 2008 Aug; 66: 222-32
    • (2008) Br J Clin Pharmacol , vol.66 , pp. 222-32
    • Goodman, T.1    Ferro, A.2    Sharma, P.3
  • 27
    • 0036183757 scopus 로고    scopus 로고
    • Towards a defini- tion of aspirin resistance: A typological approach
    • Feb
    • Weber AA, Przytulski B, Schanz A, et al. Towards a defini- tion of aspirin resistance: a typological approach. Platelets 2002 Feb; 13: 37-40
    • (2002) Platelets , vol.13 , pp. 37-40
    • Weber, A.A.1    Przytulski, B.2    Schanz, A.3
  • 28
    • 34347404722 scopus 로고    scopus 로고
    • Variable platelet response to aspirin in patients with ischemic stroke
    • Hohlfeld T, Weber AA, Junghans U, et al. Variable platelet response to aspirin in patients with ischemic stroke. Cere-brovasc Dis 2007; 24: 43-50
    • (2007) Cere-brovasc Dis , vol.24 , pp. 43-50
    • Hohlfeld, T.1    Weber, A.A.2    Junghans, U.3
  • 29
    • 0037046196 scopus 로고    scopus 로고
    • Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events
    • Apr
    • Eikelboom JW, Hirsh J, Weitz JI, et al. Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events. Circulation 2002 Apr; 105: 1650-5
    • (2002) Circulation , vol.105 , pp. 1650-5
    • Eikelboom, J.W.1    Hirsh, J.2    Weitz, J.I.3
  • 30
    • 43049115692 scopus 로고    scopus 로고
    • No case of COX-1- related aspirin resistance found in 289 patients with symptoms of stable CHD remitted for coronary angiography
    • Meen O, Brosstad F, Khiabani H, et al. No case of COX-1- related aspirin resistance found in 289 patients with symptoms of stable CHD remitted for coronary angiography. Scand J Clin Lab Invest 2008; 68: 185-91
    • (2008) Scand J Clin Lab Invest , vol.68 , pp. 185-91
    • Meen, O.1    Brosstad, F.2    Khiabani, H.3
  • 31
    • 33846235920 scopus 로고    scopus 로고
    • Prevalence of persistent platelet reactivity despite use of aspirin: A systematic review
    • Feb
    • Hovens MM, Snoep JD, Eikenboom JC, et al. Prevalence of persistent platelet reactivity despite use of aspirin: a systematic review. Am Heart J 2007 Feb; 153: 175-81
    • (2007) Am Heart J , vol.153 , pp. 175-81
    • Hovens, M.M.1    Snoep, J.D.2    Eikenboom, J.C.3
  • 32
    • 34248530551 scopus 로고    scopus 로고
    • Aspirin resistance in patients with stable coronary artery disease with and without a history of myocardial infarction
    • May
    • Dorsch MP, Lee JS, Lynch DR, et al. Aspirin resistance in patients with stable coronary artery disease with and without a history of myocardial infarction. Ann Pharmacother 2007 May; 41: 737-41
    • (2007) Ann Pharmacother , vol.41 , pp. 737-41
    • Dorsch, M.P.1    Lee, J.S.2    Lynch, D.R.3
  • 33
    • 0037454168 scopus 로고    scopus 로고
    • A prospec- tive, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease
    • Mar
    • Gum PA, Kottke-Marchant K, Welsh PA, et al. A prospec- tive, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease. J Am Coll Cardiol 2003 Mar; 41: 961-5
    • (2003) J Am Coll Cardiol , vol.41 , pp. 961-5
    • Gum, P.A.1    Kottke-Marchant, K.2    Welsh, P.A.3
  • 34
    • 34548759180 scopus 로고    scopus 로고
    • Dual antiplatelet agent failure: A new syndrome or clinical nonentity?
    • Oct
    • Barnes GD, Li J, Kline-Rogers E, et al. Dual antiplatelet agent failure: a new syndrome or clinical nonentity? Am Heart J 2007 Oct; 154: 732-5
    • (2007) Am Heart J , vol.154 , pp. 732-5
    • Barnes, G.D.1    Li, J.2    Kline-Rogers, E.3
  • 35
    • 0037276966 scopus 로고    scopus 로고
    • Aspirin non- responder status in patients with recurrent cerebral ische-mic attacks
    • Jan
    • Grundmann K, Jaschonek K, Kleine B, et al. Aspirin non- responder status in patients with recurrent cerebral ische-mic attacks. J Neurol 2003 Jan; 250: 63-6
    • (2003) J Neurol , vol.250 , pp. 63-6
    • Grundmann, K.1    Jaschonek, K.2    Kleine, B.3
  • 36
    • 21444446653 scopus 로고    scopus 로고
    • Aspirin resistance: An evaluation of current evidence and measurement methods
    • Jul
    • Martin CP, Talbert RL. Aspirin resistance: an evaluation of current evidence and measurement methods. Pharmaco-therapy 2005 Jul; 25: 942-53
    • (2005) Pharmaco-therapy , vol.25 , pp. 942-53
    • Martin, C.P.1    Talbert, R.L.2
  • 37
    • 24944474901 scopus 로고    scopus 로고
    • Aspirin resistance: Position paper of the Working Group on Aspirin Resistance
    • on be- half of the Platelet Physiology Subcommittee of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis
    • Michelson AD, Cattaneo M, Eikelboom JW, et al., on be- half of the Platelet Physiology Subcommittee of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Aspirin resistance: position paper of the Working Group on Aspirin Resistance. J Thromb Haemost 2005; 3: 1309-11
    • (2005) J Thromb Haemost , vol.3 , pp. 1309-11
    • Michelson, A.D.1    Cattaneo, M.2    Eikelboom, J.W.3
  • 38
    • 34347340649 scopus 로고    scopus 로고
    • Evaluation of dose-related effects of aspirin on platelet function: Results from the Aspirin-Induced Platelet Effect (ASPECT) study
    • Jun
    • Gurbel PA, Bliden KP, DiChiara J, et al. Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study. Circulation 2007 Jun; 115: 3156-64
    • (2007) Circulation , vol.115 , pp. 3156-64
    • Gurbel, P.A.1    Bliden, K.P.2    Dichiara, J.3
  • 39
    • 33845372276 scopus 로고    scopus 로고
    • Antiplatelet drug resistance and drug- drug interactions: Role of cytochrome P450 3A4
    • Dec
    • Lau WC, Gurbel PA. Antiplatelet drug resistance and drug- drug interactions: role of cytochrome P450 3A4. Pharm Res 2006 Dec; 23: 2691-708
    • (2006) Pharm Res , vol.23 , pp. 2691-708
    • Lau, W.C.1    Gurbel, P.A.2
  • 40
    • 34147211305 scopus 로고    scopus 로고
    • Determination of aspirin responsiveness by use of whole blood platelet ag-gregometry
    • Apr
    • Ivandic BT, Giannitsis E, Schlick P, et al. Determination of aspirin responsiveness by use of whole blood platelet ag-gregometry. Clin Chem 2007 Apr; 53: 614-9
    • (2007) Clin Chem , vol.53 , pp. 614-9
    • Ivandic, B.T.1    Giannitsis, E.2    Schlick, P.3
  • 41
    • 33847229876 scopus 로고    scopus 로고
    • Prevalence of aspirin resistance in patients with an evolving acute myo-cardial infarction
    • Poulsen TS, Jørgensen B, Korsholm L, et al. Prevalence of aspirin resistance in patients with an evolving acute myo-cardial infarction. Thromb Res 2007; 119: 555-62
    • (2007) Thromb Res , vol.119 , pp. 555-62
    • Poulsen, T.S.1    Jørgensen, B.2    Korsholm, L.3
  • 42
    • 34247203122 scopus 로고    scopus 로고
    • The effect of acetylsalicylic acid resistance on prognosis of patients who have developed acute coronary syndrome during acetyl-salicylic acid therapy
    • Mar
    • Hobikoglu GF, Norgaz T, Aksu H, et al. The effect of acetylsalicylic acid resistance on prognosis of patients who have developed acute coronary syndrome during acetyl-salicylic acid therapy. Can J Cardiol 2007 Mar; 23: 201-6
    • (2007) Can J Cardiol , vol.23 , pp. 201-6
    • Hobikoglu, G.F.1    Norgaz, T.2    Aksu, H.3
  • 43
    • 84989198039 scopus 로고    scopus 로고
    • Determination of indivi- dual response to aspirin therapy using the Accumetrics Ultegra RPFA-ASA system
    • Jun
    • Coleman JL, Wang JC, Simon DI. Determination of indivi- dual response to aspirin therapy using the Accumetrics Ultegra RPFA-ASA system. Point of Care 2004 Jun; 3: 77-82
    • (2004) Point of Care , vol.3 , pp. 77-82
    • Coleman, J.L.1    Wang, J.C.2    Simon, D.I.3
  • 44
    • 34250816849 scopus 로고    scopus 로고
    • Aspirin resistance and adverse clinical events in patients with coronary artery disease
    • Jul
    • Chen WH, Cheng X, Lee PY, et al. Aspirin resistance and adverse clinical events in patients with coronary artery disease. Am J Med 2007 Jul; 120: 631-5
    • (2007) Am J Med , vol.120 , pp. 631-5
    • Chen, W.H.1    Cheng, X.2    Lee, P.Y.3
  • 45
    • 38149124125 scopus 로고    scopus 로고
    • Can aspirin resistance be clinically predicted in stroke patients?
    • Feb
    • Seok JI, Joo IS, Yoon JH, et al. Can aspirin resistance be clinically predicted in stroke patients? Clin Neurol Neuro-surg 2008 Feb; 110: 110-6
    • (2008) Clin Neurol Neuro-surg , vol.110 , pp. 110-6
    • Seok, J.I.1    Joo, I.S.2    Yoon, J.H.3
  • 46
    • 18244392669 scopus 로고    scopus 로고
    • Screening for aspirin responsiveness after transient ischemic attack and stroke: Comparison of 2 point-of-care platelet function tests with optical aggregometry
    • May
    • Harrison P, Segal H, Blasbery K, et al. Screening for aspirin responsiveness after transient ischemic attack and stroke: comparison of 2 point-of-care platelet function tests with optical aggregometry. Stroke 2005 May; 36: 1001-5
    • (2005) Stroke , vol.36 , pp. 1001-5
    • Harrison, P.1    Segal, H.2    Blasbery, K.3
  • 47
    • 37749053508 scopus 로고    scopus 로고
    • Screening for aspirin resistance in stable coronary artery patients by three different tests
    • Chakroun T, Addad F, Abderazek F, et al. Screening for aspirin resistance in stable coronary artery patients by three different tests. Thromb Res 2007; 121: 413-8
    • (2007) Thromb Res , vol.121 , pp. 413-8
    • Chakroun, T.1    Addad, F.2    Abderazek, F.3
  • 48
    • 34548331542 scopus 로고    scopus 로고
    • Platelet function measured by VerifyNow® identifies generalized high platelet reactivity in aspirin treated patients
    • Sep
    • Dichiara J, Bliden KP, Tantry US, et al. Platelet function measured by VerifyNow® identifies generalized high platelet reactivity in aspirin treated patients. Platelets 2007 Sep; 18: 414-23
    • (2007) Platelets , vol.18 , pp. 414-23
    • Dichiara, J.1    Bliden, K.P.2    Tantry, U.S.3
  • 49
    • 13244274961 scopus 로고    scopus 로고
    • Platelet activation in type 2 diabetes mellitus
    • Aug
    • Ferroni P, Basili S, Falco A, et al. Platelet activation in type 2 diabetes mellitus. J Thromb Haemost 2004 Aug; 2: 1282-91
    • (2004) J Thromb Haemost , vol.2 , pp. 1282-91
    • Ferroni, P.1    Basili, S.2    Falco, A.3
  • 50
    • 23644433510 scopus 로고    scopus 로고
    • Plate- let function profiles in patients with type 2 diabetes and coronary artery disease on combined aspirin and clopido-grel treatment
    • Aug
    • Angiolillo DJ, Fernandez-Ortiz A, Bernardo E, et al. Plate- let function profiles in patients with type 2 diabetes and coronary artery disease on combined aspirin and clopido-grel treatment. Diabetes 2005 Aug; 54: 2430-5
    • (2005) Diabetes , vol.54 , pp. 2430-5
    • Angiolillo, D.J.1    Fernandez-Ortiz, A.2    Bernardo, E.3
  • 51
    • 35649016721 scopus 로고    scopus 로고
    • Aspirin-induced platelet inhibition in patients undergoing cardiac surgery
    • Nov
    • Zimmermann N, Kurt M, Winter J, et al. Aspirin-induced platelet inhibition in patients undergoing cardiac surgery. Platelets 2007 Nov; 18: 528-34
    • (2007) Platelets , vol.18 , pp. 528-34
    • Zimmermann, N.1    Kurt, M.2    Winter, J.3
  • 52
    • 34247554956 scopus 로고    scopus 로고
    • Platelet aggregation and aspirin non-responsiveness increase when an acute coronary syndrome is complicated by an infection
    • Mar
    • Modica A, Karlsson F, Mooe T. Platelet aggregation and aspirin non-responsiveness increase when an acute coronary syndrome is complicated by an infection. J Thromb Haemost 2007 Mar; 5: 507-11
    • (2007) J Thromb Haemost , vol.5 , pp. 507-11
    • Modica, A.1    Karlsson, F.2    Mooe, T.3
  • 53
    • 10444235983 scopus 로고    scopus 로고
    • Clopidogrel resistance: A new chapter in a fast-moving story
    • Jun
    • WiviottSD, Antman EM. Clopidogrel resistance: a new chapter in a fast-moving story. Circulation 2004 Jun; 109: 3064-7
    • (2004) Circulation , vol.109 , pp. 3064-7
    • Wiviotts, D.1    Antman, E.M.2
  • 55
    • 38449103046 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 loss-of-function polymorphism, but not CYP3A4 IVS10+12G/A and P2Y12 T744C polymorphisms, is associated with response variability to dual antiplatelet treatment in high-risk vascular patients
    • Dec
    • Giusti B, Gori AM, Marcucci R, et al. Cytochrome P450 2C19 loss-of-function polymorphism, but not CYP3A4 IVS10+12G/A and P2Y12 T744C polymorphisms, is associated with response variability to dual antiplatelet treatment in high-risk vascular patients. Pharmacogenet Genomics 2007 Dec; 17: 1057-64
    • (2007) Pharmacogenet Genomics , vol.17 , pp. 1057-64
    • Giusti, B.1    Gori, A.M.2    Marcucci, R.3
  • 56
    • 45249088224 scopus 로고    scopus 로고
    • The effect of CYP2C19 polymorphism on the pharmacokinetics and pharmacodynamics of clopidogrel: A possible mechanism for clopidogrel resistance
    • Aug
    • Kim KA, Park PW, Hong SJ, et al. The effect of CYP2C19 polymorphism on the pharmacokinetics and pharmacodynamics of clopidogrel: a possible mechanism for clopidogrel resistance. Clin Pharmacol Ther 2008 Aug; 84: 236-42
    • (2008) Clin Pharmacol Ther , vol.84 , pp. 236-42
    • Kim, K.A.1    Park, P.W.2    Hong, S.J.3
  • 57
    • 33749339075 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects
    • Oct
    • Hulot JS, Bura A, Villard E, et al. Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects. Blood 2006 Oct; 108: 2244-7
    • (2006) Blood , vol.108 , pp. 2244-7
    • Hulot, J.S.1    Bura, A.2    Villard, E.3
  • 58
    • 33746792912 scopus 로고    scopus 로고
    • Contri- bution of gene sequence variations of the hepatic cytochrome P450 3A4 enzyme to variability in individual responsiveness to clopidogrel
    • Aug
    • Angiolillo DJ, Fernandez-Ortiz A, Bernardo E, et al. Contri- bution of gene sequence variations of the hepatic cytochrome P450 3A4 enzyme to variability in individual responsiveness to clopidogrel. Arterioscler Thromb Vasc Biol 2006 Aug; 26: 1895-900
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1895-900
    • Angiolillo, D.J.1    Fernandez-Ortiz, A.2    Bernardo, E.3
  • 59
    • 58749094444 scopus 로고    scopus 로고
    • Cytochrome p-450 polymorphisms and response to clopidogrel
    • Jan
    • Mega JL, Close SL, Wiviott SD, et al. Cytochrome p-450 polymorphisms and response to clopidogrel. N Engl J Med 2009 Jan; 360: 354-62
    • (2009) N Engl J Med , vol.360 , pp. 354-62
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 60
    • 58749090547 scopus 로고    scopus 로고
    • French Registry of Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI) Investigators. Genetic determinants of response to clopidogrel and cardiovascular events
    • Jan
    • Simon T, Verstuyft C, Mary-Krause M, et al., French Registry of Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI) Investigators. Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med 2009 Jan; 360: 363-75
    • (2009) N Engl J Med , vol.360 , pp. 363-75
    • Simon, T.1    Verstuyft, C.2    Mary-Krause, M.3
  • 61
    • 38349065084 scopus 로고    scopus 로고
    • Influence of ome- prazole on the antiplatelet action of clopidogrel associated with aspirin: The randomized, double-blind OCLA (Ome-prazole CLopidogrel Aspirin) study
    • Jan
    • Gilard M, Arnaud B, Cornily JC, et al. Influence of ome- prazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (Ome-prazole CLopidogrel Aspirin) study. J Am Coll Cardiol 2008 Jan; 51: 256-60
    • (2008) J Am Coll Cardiol , vol.51 , pp. 256-60
    • Gilard, M.1    Arnaud, B.2    Cornily, J.C.3
  • 62
    • 40749094082 scopus 로고    scopus 로고
    • Effects of the proton pump inhibitor lansoprazole on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel
    • Apr
    • Small DS, Farid NA, Payne CD, et al. Effects of the proton pump inhibitor lansoprazole on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel. J Clin Pharmacol 2008 Apr; 48: 475-84
    • (2008) J Clin Pharmacol , vol.48 , pp. 475-84
    • Small, D.S.1    Farid, N.A.2    Payne, C.D.3
  • 63
    • 73449104954 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration [online]. Available from URL Accessed 2010 Sep 6
    • U.S. Food and Drug Administration. Clopidogrel (mar- keted as Plavix) and omeprazole (marketed as Prilosec): drug interaction [online]. Available from URL: http:// www.fda.gov/Safety/MedWatch/SafetyInformation/Safety AlertsforHumanMedicalProducts/ucm190848.htm [Accessed 2010 Sep 6]
    • Clopidogrel (Mar- Keted As Plavix) and Omeprazole (Marketed As Prilosec): Drug Interaction
  • 64
    • 67649372663 scopus 로고    scopus 로고
    • Assessment, mechanisms, and clinical implication of variability in platelet response to aspirin and clopidogrel therapy
    • Ben-Dor I, Kleiman NS, Lev E. Assessment, mechanisms, and clinical implication of variability in platelet response to aspirin and clopidogrel therapy. Am J Cardiol 2009; 104: 227-33
    • (2009) Am J Cardiol , vol.104 , pp. 227-33
    • Ben-Dor, I.1    Kleiman, N.S.2    Lev, E.3
  • 65
    • 39649097856 scopus 로고    scopus 로고
    • Prevalence and 2 risk factors for aspirin and clopidogrel resistance in cerebrovascular stenting
    • Feb
    • Prabhakaran S, Wells KR, Lee VH, et al. Prevalence and 2 risk factors for aspirin and clopidogrel resistance in cerebrovascular stenting. AJNR Am J Neuroradiol 2008 Feb; 29: 281-5
    • (2008) AJNR Am J Neuroradiol , vol.29 , pp. 281-5
    • Prabhakaran, S.1    Wells, K.R.2    Lee, V.H.3
  • 66
    • 35549008493 scopus 로고    scopus 로고
    • Platelet function monitoring in patients with coronary artery disease
    • Gurbel PA, Becker RC, Mann KG, et al. Platelet function monitoring in patients with coronary artery disease. J Am Coll Cardiol 2007; 50: 1822-34
    • (2007) J Am Coll Cardiol , vol.50 , pp. 1822-34
    • Gurbel, P.A.1    Becker, R.C.2    Mann, K.G.3
  • 67
    • 0038649988 scopus 로고    scopus 로고
    • Clopidogrel for coronary stenting: Response variability, drug resistance, and the effect of pretreatment platelet reactivity
    • Jun
    • Gurbel PA, Bliden KP, Hiatt BL, et al. Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity. Circulation 2003 Jun; 107: 2908-13
    • (2003) Circulation , vol.107 , pp. 2908-13
    • Gurbel, P.A.1    Bliden, K.P.2    Hiatt, B.L.3
  • 68
    • 8344221349 scopus 로고    scopus 로고
    • Clopidogrel re- sistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction
    • Jun
    • Matetzky S, Shenkman B, Guetta V, et al. Clopidogrel re- sistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction. Circulation 2004 Jun; 109: 3171-5
    • (2004) Circulation , vol.109 , pp. 3171-5
    • Matetzky, S.1    Shenkman, B.2    Guetta, V.3
  • 69
    • 78649345381 scopus 로고    scopus 로고
    • Platelet monitoring of clopidogrel response using VASP phosphorylation index decreases rate of major adverse cardiovascular events in patients with clopidogrel resistance: A multicenter randomized prospective study
    • Mar 29; Chicago (IL)
    • Bonello L. Platelet monitoring of clopidogrel response using VASP phosphorylation index decreases rate of major adverse cardiovascular events in patients with clopidogrel resistance: a multicenter randomized prospective study. American College of Cardiology Scientific Sessions/i2 Summit-SCAI Annual Meeting; 2008 Mar 29; Chicago (IL).
    • (2008) American College of Cardiology Scientific Sessions/i2 Summit-SCAI Annual Meeting
    • Bonello, L.1
  • 70
    • 78649365402 scopus 로고    scopus 로고
    • [online]. Available from URL Accessed 2010 Sep 6
    • Late breaking clinical trials I [online]. Available from URL: http://www.the heart.org/article/850995.do [Accessed 2010 Sep 6]
    • Late Breaking Clinical Trials i
  • 71
    • 68949183521 scopus 로고    scopus 로고
    • Effect of prasugrel versus clopidogrel on outcomes among patients with acute coronary syndrome undergoing percutaneous coronary intervention without stent implantation: A TRial to assess Improvement in Therapeutic Outcomes by optimizing platelet inhibitioN with prasugrel (TRI-TON)-Thrombolysis in Myocardial Infarction (TIMI) 38 substudy
    • TIMI Study Group Sep
    • Pride YB, Wiviott SD, Buros JL, et al., TIMI Study Group. Effect of prasugrel versus clopidogrel on outcomes among patients with acute coronary syndrome undergoing percutaneous coronary intervention without stent implantation: a TRial to assess Improvement in Therapeutic Outcomes by optimizing platelet inhibitioN with prasugrel (TRI-TON)-Thrombolysis in Myocardial Infarction (TIMI) 38 substudy. Am Heart J 2009 Sep; 158 (3): e21-6
    • (2009) Am Heart J , vol.158 , Issue.3
    • Pride, Y.B.1    Wiviott, S.D.2    Buros, J.L.3
  • 72
    • 56849130022 scopus 로고    scopus 로고
    • Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo
    • Dec 9
    • Erlinge D, Varenhorst C, Braun OO, et al. Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo. J Am Coll Cardiol 2008 Dec 9; 52 (24): 1968-77
    • (2008) J Am Coll Cardiol , vol.52 , Issue.24 , pp. 1968-77
    • Erlinge, D.1    Varenhorst, C.2    Braun, O.O.3
  • 73
    • 0035845683 scopus 로고    scopus 로고
    • Near-field amplification of antithrombotic ef- fects of dipyridamole through vessel wall cells
    • Eisert WG. Near-field amplification of antithrombotic ef- fects of dipyridamole through vessel wall cells. Neurology 2001; 57 (5 Suppl. 2): S20-3
    • (2001) Neurology , vol.57 , Issue.5 SUPPL. 2
    • Eisert, W.G.1
  • 74
    • 78649338651 scopus 로고    scopus 로고
    • The significance of optimised for- mulation for dipyridamole in stroke risk reduction
    • Derendorf H, Estes K. The significance of optimised for- mulation for dipyridamole in stroke risk reduction. Eur Neurol Dis 2007; (2): 21-3
    • (2007) Eur Neurol Dis , Issue.2 , pp. 21-3
    • Derendorf, H.1    Estes, K.2
  • 75
    • 30944446787 scopus 로고    scopus 로고
    • Dipyridamole de- creases protease-activated receptor and annexin-v binding on platelets of post stroke patients with aspirin non-responsiveness
    • Serebruany V, Malinin A, Ziai W, et al. Dipyridamole de- creases protease-activated receptor and annexin-v binding on platelets of post stroke patients with aspirin non-responsiveness. Cerebrovasc Dis 2006; 21: 98-105
    • (2006) Cerebrovasc Dis , vol.21 , pp. 98-105
    • Serebruany, V.1    Malinin, A.2    Ziai, W.3
  • 76
    • 0037335810 scopus 로고    scopus 로고
    • Dipyridamole enhances NO/cGMP-mediated vasodilator-stimulated phosphoprotein phosphorylation and signaling in human platelets: In vitro and in vivo/ex vivo studies
    • Mar
    • Aktas B, Utz A, Hoenig-Liedl P, et al. Dipyridamole enhances NO/cGMP-mediated vasodilator-stimulated phosphoprotein phosphorylation and signaling in human platelets: in vitro and in vivo/ex vivo studies. Stroke 2003 Mar; 34: 764-9
    • (2003) Stroke , vol.34 , pp. 764-9
    • Aktas, B.1    Utz, A.2    Hoenig-Liedl, P.3
  • 77
    • 58049213577 scopus 로고    scopus 로고
    • Flow cyto- metric assessment of vasodilator-stimulated phosphopro-tein: Prognostic value of recurrent cardiovascular events after acute coronary syndromes
    • Nov-Dec
    • Cayla G, Macia JC, Rabesandratana H, et al. Flow cyto- metric assessment of vasodilator-stimulated phosphopro-tein: prognostic value of recurrent cardiovascular events after acute coronary syndromes. Arch Cardiovasc Dis 2008 Nov-Dec; 101: 743-51
    • (2008) Arch Cardiovasc Dis , vol.101 , pp. 743-51
    • Cayla, G.1    MacIa, J.C.2    Rabesandratana, H.3
  • 78
    • 33646596912 scopus 로고    scopus 로고
    • Aspirin plus dipyridamole versus aspirin alone after cerebral is-chaemia of arterial origin (ESPRIT): Randomised controlled trial
    • May
    • ESPRIT Study Group, Halkes PH, van Gijn J, et al. Aspirin plus dipyridamole versus aspirin alone after cerebral is-chaemia of arterial origin (ESPRIT): randomised controlled trial. Lancet 2006 May; 367: 1665-73
    • (2006) Lancet , vol.367 , pp. 1665-73
    • Study Group, E.1    Halkes, P.H.2    Van Gijn, J.3
  • 79
    • 0035028314 scopus 로고    scopus 로고
    • Cardiac safety in the European Stroke Prevention Study 2 (ESPS2)
    • Apr
    • Diener HC, Darius H, Bertrand-Hardy JM, et al. Cardiac safety in the European Stroke Prevention Study 2 (ESPS2). Int J Clin Pract 2001 Apr; 55: 162-3
    • (2001) Int J Clin Pract , vol.55 , pp. 162-3
    • Diener, H.C.1    Darius, H.2    Bertrand-Hardy, J.M.3
  • 80
    • 34848847773 scopus 로고    scopus 로고
    • Clinical implications of aspirin resis- tance
    • Sep
    • Patel D, Moonis M. Clinical implications of aspirin resis- tance. Expert Rev Cardiovasc Ther 2007 Sep; 5: 969-75
    • (2007) Expert Rev Cardiovasc Ther , vol.5 , pp. 969-75
    • Patel, D.1    Moonis, M.2
  • 81
    • 45949108549 scopus 로고    scopus 로고
    • Antithrombotic and thrombolytic therapy: American College of Chest Physicians evidence-based clinical practice guidelines (8th edition)
    • American College of Chest Physicians Jun
    • Hirsh J, Guyatt G, Albers GW, et al., American College of Chest Physicians. Antithrombotic and thrombolytic therapy: American College of Chest Physicians evidence-based clinical practice guidelines (8th edition). Chest 2008 Jun; 133 (6 Suppl.): 110S-2S
    • (2008) Chest , vol.133 , Issue.6 SUPPL.
    • Hirsh, J.1    Guyatt, G.2    Albers, G.W.3
  • 82
    • 33846413188 scopus 로고    scopus 로고
    • Increased basal platelet activity, plasma adiponectin levels, and diabetes mellitus are associated with poor platelet responsiveness to in vitro effect of aspirin
    • Takahashi S, Ushida M, Komine R, et al. Increased basal platelet activity, plasma adiponectin levels, and diabetes mellitus are associated with poor platelet responsiveness to in vitro effect of aspirin. Thromb Res 2007; 119: 517-24
    • (2007) Thromb Res , vol.119 , pp. 517-24
    • Takahashi, S.1    Ushida, M.2    Komine, R.3
  • 83
    • 33747088257 scopus 로고    scopus 로고
    • Residual arachidonic acid-induced platelet activation via an adeno-sine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: A 700-patient study of aspirin resistance
    • Jun
    • Frelinger 3rd AL, Furman MI, Linden MD, et al. Residual arachidonic acid-induced platelet activation via an adeno-sine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance. Circulation 2006 Jun; 113: 2888-96
    • (2006) Circulation , vol.113 , pp. 2888-96
    • Frelinger Iii, A.L.1    Furman, M.I.2    Linden, M.D.3
  • 84
    • 34447538155 scopus 로고    scopus 로고
    • The additive anti- platelet action of clopidogrel in patients with coronary artery disease treated with aspirin
    • Jul
    • Dropinski J, Jakiela B, Sanak M, et al. The additive anti- platelet action of clopidogrel in patients with coronary artery disease treated with aspirin. Thromb Haemost 2007 Jul; 98: 201-9
    • (2007) Thromb Haemost , vol.98 , pp. 201-9
    • Dropinski, J.1    Jakiela, B.2    Sanak, M.3
  • 85
    • 60649084742 scopus 로고    scopus 로고
    • Effect of high dose statin therapy on platelet function; Statins reduce aspirin-resistant platelet aggregation in patients with coronary heart disease
    • Jan
    • Tirnaksiz E, Pamukcu B, Oflaz H, et al. Effect of high dose statin therapy on platelet function; statins reduce aspirin-resistant platelet aggregation in patients with coronary heart disease. J Thromb Thrombolysis 2009 Jan; 27: 2724-8
    • (2009) J Thromb Thrombolysis , vol.27 , pp. 2724-8
    • Tirnaksiz, E.1    Pamukcu, B.2    Oflaz, H.3
  • 86
    • 74649085430 scopus 로고    scopus 로고
    • Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (PLATO): A randomised double-blind study
    • PLATelet in- hibition and patient Outcomes Investigators Jan 23
    • Cannon CP, Harrington RA, James S, et al., PLATelet in- hibition and patient Outcomes Investigators. Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (PLATO): a randomised double-blind study. Lancet 2010 Jan 23; 375 (9711): 283-93
    • (2010) Lancet , vol.375 , Issue.9711 , pp. 283-93
    • Cannon, C.P.1    Harrington, R.A.2    James, S.3


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