Kallikrein-binding protein inhibits LPS-induced TNF-α by upregulating SOCS3 expression

Journal of Cellular Biochemistry

Volumn 114, Issue 5, 2013, Pages 1020-1028

  Dai, Zhiyu ^a   Lu, Lei ^b   Yang, Zhonghan ^a   Mao, Yuling ^a   Lu, Juling ^a   Li, Cen ^a   Qi, Weiwei ^a   Chen, Yifei ^a   Yao, Yachao ^a   Li, Lei ^a   Chen, Shaobo ^a   Zhang, Yang ^c   Cai, Weibin ^a   Yang, Xia ^a,d   Gao, Guoquan ^a,d  

^a SUN YAT SEN UNIVERSITY   (China)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

^c GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^d SUN YAT SEN UNIVERSITY   (China)

Author keywords

anti inflammation; endotoxin; macrophage; SERPINA3K; TNF

Indexed keywords

BETA CATENIN; KALLIKREIN BINDING PROTEIN; LIPOPOLYSACCHARIDE; LUCIFERASE; SERINE PROTEINASE INHIBITOR; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; INFLAMMATION; MACROPHAGE; MALE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; SEPTIC SHOCK; SURVIVAL RATE; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BETA CATENIN; ENDOTOXINS; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; NF-KAPPA B; RATS; SERPINS; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; SURVIVAL ANALYSIS; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84875190816     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24441     Document Type: Article

References (34)

1. Alexander WS, Hilton DJ,. 2004. The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response. Annu Rev Immunol 22: 503-529.
2. Blackwell TS, Christman JW,. 1997. The role of nuclear factor-kappa B in cytokine gene regulation. Am J Respir Cell Mol Biol 17: 3-9.
3. Chai KX, Ma JX, Murray SR, Chao J, Chao L,. 1991. Molecular cloning and analysis of the rat kallikrein-binding protein gene. J Biol Chem 266: 16029-16036.
4. Chao J, Chai KX, Chen LM, Xiong W, Chao S, Woodley-Miller C, Wang LX, Lu HS, Chao L,. 1990. Tissue kallikrein-binding protein is a serpin. I. Purification, characterization, and distribution in normotensive and spontaneously hypertensive rats. J Biol Chem 265: 16394-16401.
5. Chen LM, Chao L, Chao J,. 1997. Beneficial effects of kallikrein-binding protein in transgenic mice during endotoxic shock. Life Sci 60: 1431-1435.
6. Denys A, Udalova IA, Smith C, Williams LM, Ciesielski CJ, Campbell J, Andrews C, Kwaitkowski D, Foxwell BM,. 2002. Evidence for a dual mechanism for IL-10 suppression of TNF-alpha production that does not involve inhibition of p38 mitogen-activated protein kinase or NF-kappa B in primary human macrophages. J Immunol 168: 4837-4845.
7. Duan Y, Liao AP, Kuppireddi S, Ye Z, Ciancio MJ, Sun J,. 2007. beta-Catenin activity negatively regulates bacteria-induced inflammation. Lab Invest 87: 613-624.
8. Falvo JV, Tsytsykova AV, Goldfeld AE,. 2010. Transcriptional control of the TNF gene. Curr Dir Autoimmun 11: 27-60.
9. Frobose H, Ronn SG, Heding PE, Mendoza H, Cohen P, Mandrup-Poulsen T, Billestrup N,. 2006. Suppressor of cytokine signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex. Mol Endocrinol 20: 1587-1596.
10. Fujimoto M, Naka T,. 2010. SOCS1, a negative regulator of cytokine signals and TLR responses, in human liver diseases. Gastroenterol Res Pract 2010: 470468.
11. Gao G, Shao C, Zhang SX, Dudley A, Fant J, Ma JX,. 2003. Kallikrein-binding protein inhibits retinal neovascularization and decreases vascular leakage. Diabetologia 46: 689-698.
12. Guha M, Mackman N,. 2001. LPS induction of gene expression in human monocytes. Cell Signal 13: 85-94.
13. Howard M, Muchamuel T, Andrade S, Menon S,. 1993. Interleukin 10 protects mice from lethal endotoxemia. J Exp Med 177: 1205-1208.
14. Jo D, Liu D, Yao S, Collins RD, Hawiger J,. 2005. Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis. Nat Med 11: 892-898.
15. Kim JS, Yeo S, Shin DG, Bae YS, Lee JJ, Chin BR, Lee CH, Baek SH,. 2010. Glycogen synthase kinase 3beta and beta-catenin pathway is involved in toll-like receptor 4-mediated NADPH oxidase 1 expression in macrophages. FEBS J 277: 2830-2837.
16. Kinjyo I, Hanada T, Inagaki-Ohara K, Mori H, Aki D, Ohishi M, Yoshida H, Kubo M, Yoshimura A,. 2002. SOCS1/JAB is a negative regulator of LPS-induced macrophage activation. Immunity 17: 583-591.
17. Lee H, Bae S, Choi BW, Yoon Y,. 2012. WNT/beta-catenin pathway is modulated in asthma patients and LPS-stimulated RAW264.7 macrophage cell line. Immunopharmacol Immunotoxicol 34: 56-65.
18. Liu X, Lin Z, Zhou T, Zong R, He H, Liu Z, Ma JX, Liu Z, Zhou Y,. 2011. Anti-angiogenic and anti-inflammatory effects of SERPINA3K on corneal injury. PLoS ONE 6: e16712.
19. Lu L, Yang Z, Zhu B, Fang S, Yang X, Cai W, Li C, Ma JX, Gao G,. 2007. Kallikrein-binding protein suppresses growth of hepatocellular carcinoma by anti-angiogenic activity. Cancer Lett 257: 97-106.
20. Moore KW, de Waal MR, Coffman RL, O'Garra A,. 2001. Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol 19: 683-765.
21. Nakagawa R, Naka T, Tsutsui H, Fujimoto M, Kimura A, Abe T, Seki E, Sato S, Takeuchi O, Takeda K, Akira S, Yamanishi K, Kawase I, Nakanishi K, Kishimoto T,. 2002. SOCS-1 participates in negative regulation of LPS responses. Immunity 17: 677-687.
22. Qasimi P, Ming-Lum A, Ghanipour A, Ong CJ, Cox ME, Ihle J, Cacalano N, Yoshimura A, Mui AL,. 2006. Divergent mechanisms utilized by SOCS3 to mediate interleukin-10 inhibition of tumor necrosis factor alpha and nitric oxide production by macrophages. J Biol Chem 281: 6316-6324.
23. Rothlin CV, Ghosh S, Zuniga EI, Oldstone MB, Lemke G,. 2007. TAM receptors are pleiotropic inhibitors of the innate immune response. Cell 131: 1124-1136.
24. Schaale K, Neumann J, Schneider D, Ehlers S, Reiling N,. 2011. Wnt signaling in macrophages: Augmenting and inhibiting mycobacteria-induced inflammatory responses. Eur J Cell Biol 90: 553-559.
25. Shebzukhov I, Kuprash DV,. 2011. Transcriptional regulation of TNF/LT locus in immune cells. Mol Biol (Mosk) 45: 56-67.
26. Swantek JL, Christerson L, Cobb MH,. 1999. Lipopolysaccharide-induced tumor necrosis factor-alpha promoter activity is inhibitor of nuclear factor-kappaB kinase-dependent. J Biol Chem 274: 11667-11671.
27. Tsytsykova AV, Falvo JV, Schmidt-Supprian M, Courtois G, Thanos D, Goldfeld AE,. 2007. Post-induction, stimulus-specific regulation of tumor necrosis factor mRNA expression. J Biol Chem 282: 11629-11638.
28. Wajant H, Pfizenmaier K, Scheurich P,. 2003. Tumor necrosis factor signaling. Cell Death Differ 10: 45-65.
29. Yoshimura A, Nishinakamura H, Matsumura Y, Hanada T,. 2005. Negative regulation of cytokine signaling and immune responses by SOCS proteins. Arthritis Res Ther 7: 100-110.
30. Yoshimura A, Naka T, Kubo M,. 2007. SOCS proteins, cytokine signalling and immune regulation. Nat Rev Immunol 7: 454-465.
31. Zhang B, Ma JX,. 2008. SERPINA3K prevents oxidative stress induced necrotic cell death by inhibiting calcium overload. PLoS ONE 3: e4077.
32. Zhang B, Hu Y, Ma JX,. 2009. Anti-inflammatory and antioxidant effects of SERPINA3K in the retina. Invest Ophthalmol Vis Sci 50: 3943-3952.
33. Zhang B, Abreu JG, Zhou K, Chen Y, Hu Y, Zhou T, He X, Ma JX,. 2010. Blocking the Wnt pathway, a unifying mechanism for an angiogenic inhibitor in the serine proteinase inhibitor family. Proc Natl Acad Sci USA 107: 6900-6905.
34. Zhu B, Lu L, Cai W, Yang X, Li C, Yang Z, Zhan W, Ma JX, Gao G,. 2007. Kallikrein-binding protein inhibits growth of gastric carcinoma by reducing vascular endothelial growth factor production and angiogenesis. Mol Cancer Ther 6: 3297-3306.