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Volumn 75, Issue 4, 2013, Pages 931-943

Current and emerging antiviral treatments for hepatitis C infection

Author keywords

Antiviral therapy; Direct acting antiviral; Hepatitis C virus; Polymerase inhibitors; Protease inhibitors

Indexed keywords

ALISPORIVIR; ANA 733; ANTIVIRUS AGENT; ASUNAPREVIR; BOCEPREVIR; CYCLOPHILIN INHIBITOR; DACLATASVIR; DANOPREVIR; ERYTHROPOIETIN; GI 5005; IMMUNOMODULATING AGENT; IMO 2125; INTERLEUKIN 28B; MACROGOL; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MERICITABINE; MICRORNA 122; MIRAVIRSEN; NITAZOXANIDE; NONSTRUCTURAL PROTEIN 2; NONSTRUCTURAL PROTEIN 5; PEGINTERFERON ALPHA2A; PEGINTERFERON ALPHA2B; RIBAVIRIN; SOFOSBUVIR; TARIBAVIRIN; TEGOBUVIR; TELAPREVIR; UNCLASSIFIED DRUG;

EID: 84875077230     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2012.04419.x     Document Type: Article
Times cited : (48)

References (90)
  • 1
    • 84856188637 scopus 로고    scopus 로고
    • A watershed moment in the treatment of hepatitis C
    • Chung RT. A watershed moment in the treatment of hepatitis C. N Engl J Med 2012; 366: 273-275.
    • (2012) N Engl J Med , vol.366 , pp. 273-275
    • Chung, R.T.1
  • 2
    • 33748114343 scopus 로고    scopus 로고
    • The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide
    • Perz JF, Armstrong GL, Farrington LA, Hutin YJ, Bell BP. The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide. J Hepatol 2006; 45: 529-538.
    • (2006) J Hepatol , vol.45 , pp. 529-538
    • Perz, J.F.1    Armstrong, G.L.2    Farrington, L.A.3    Hutin, Y.J.4    Bell, B.P.5
  • 3
    • 59149085501 scopus 로고    scopus 로고
    • The global burden of hepatitis C
    • Lavanchy D. The global burden of hepatitis C. Liver Int 2009; 29: 74-81.
    • (2009) Liver Int , vol.29 , pp. 74-81
    • Lavanchy, D.1
  • 4
    • 84857144025 scopus 로고    scopus 로고
    • The increasing burden of mortality from viral hepatitis in the United States between 1999 and 2007
    • Ly KN, Xing J, Klevens RM, Jiles RB, Ward JW, Holmberg SD. The increasing burden of mortality from viral hepatitis in the United States between 1999 and 2007. Ann Intern Med 2012; 156: 271-278.
    • (2012) Ann Intern Med , vol.156 , pp. 271-278
    • Ly, K.N.1    Xing, J.2    Klevens, R.M.3    Jiles, R.B.4    Ward, J.W.5    Holmberg, S.D.6
  • 5
    • 0036830454 scopus 로고    scopus 로고
    • Side effects of therapy of hepatitis C and their management
    • Fried MW. Side effects of therapy of hepatitis C and their management. Hepatology 2002; 36: S237-244.
    • (2002) Hepatology , vol.36
    • Fried, M.W.1
  • 7
    • 77957899129 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of peginterferon and ribavirin: implications for clinical efficacy in the treatment of chronic hepatitis C
    • Noureddin M, Ghany MG. Pharmacokinetics and pharmacodynamics of peginterferon and ribavirin: implications for clinical efficacy in the treatment of chronic hepatitis C. Gastroenterol Clin North Am 2010; 39: 649-658.
    • (2010) Gastroenterol Clin North Am , vol.39 , pp. 649-658
    • Noureddin, M.1    Ghany, M.G.2
  • 8
    • 58149295953 scopus 로고    scopus 로고
    • Ribavirin: current role in the optimal clinical management of chronic hepatitis C
    • Reddy KR, Nelson DR, Zeuzem S. Ribavirin: current role in the optimal clinical management of chronic hepatitis C. J Hepatol 2009; 50: 402-411.
    • (2009) J Hepatol , vol.50 , pp. 402-411
    • Reddy, K.R.1    Nelson, D.R.2    Zeuzem, S.3
  • 9
    • 79953741413 scopus 로고    scopus 로고
    • Sustained virologic response to antiviral therapy for chronic hepatitis C virus infection: a cure and so much more
    • Pearlman BL, Traub N. Sustained virologic response to antiviral therapy for chronic hepatitis C virus infection: a cure and so much more. Clin Infect Dis 2011; 52: 889-900.
    • (2011) Clin Infect Dis , vol.52 , pp. 889-900
    • Pearlman, B.L.1    Traub, N.2
  • 11
    • 84872278397 scopus 로고    scopus 로고
    • Acute hepatitis C infection: new approaches to surveillance, treatment and prevention. Curr Hepatitis Rep ; doi: 10.1007/s11901-012-0143-5. in press.
    • Doyle JS, Sacks-Davis R, Hellard ME. Acute hepatitis C infection: new approaches to surveillance, treatment and prevention. Curr Hepatitis Rep 2012; doi: 10.1007/s11901-012-0143-5. in press.
    • (2012)
    • Doyle, J.S.1    Sacks-Davis, R.2    Hellard, M.E.3
  • 14
    • 0036240477 scopus 로고    scopus 로고
    • Mechanism of action of ribavirin in the combination treatment of chronic HCV infection
    • Lau JY, Tam RC, Liang TJ, Hong Z. Mechanism of action of ribavirin in the combination treatment of chronic HCV infection. Hepatology 2002; 35: 1002-1009.
    • (2002) Hepatology , vol.35 , pp. 1002-1009
    • Lau, J.Y.1    Tam, R.C.2    Liang, T.J.3    Hong, Z.4
  • 16
    • 80052042080 scopus 로고    scopus 로고
    • IL28B polymorphism and genetic biomarkers of viral clearance in hepatitis C virus infection
    • Holmes JA, Sievert W, Thompson AJ. IL28B polymorphism and genetic biomarkers of viral clearance in hepatitis C virus infection. Biomark Med 2011; 5: 461-478.
    • (2011) Biomark Med , vol.5 , pp. 461-478
    • Holmes, J.A.1    Sievert, W.2    Thompson, A.J.3
  • 19
    • 79951545875 scopus 로고    scopus 로고
    • A review of the treatment of chronic hepatitis C virus infection in cirrhosis
    • Vezali E, Aghemo A, Colombo M. A review of the treatment of chronic hepatitis C virus infection in cirrhosis. Clin Ther 2010; 32: 2117-2138.
    • (2010) Clin Ther , vol.32 , pp. 2117-2138
    • Vezali, E.1    Aghemo, A.2    Colombo, M.3
  • 20
    • 50649112802 scopus 로고    scopus 로고
    • Treatment predictors of a sustained virologic response in hepatitis B and C
    • Kau A, Vermehren J, Sarrazin C. Treatment predictors of a sustained virologic response in hepatitis B and C. J Hepatol 2008; 49: 634-651.
    • (2008) J Hepatol , vol.49 , pp. 634-651
    • Kau, A.1    Vermehren, J.2    Sarrazin, C.3
  • 21
    • 79960453276 scopus 로고    scopus 로고
    • EASL Clinical Practice Guidelines: management of hepatitis C virus infection
    • European Association for the Study of the Liver
    • European Association for the Study of the Liver. EASL Clinical Practice Guidelines: management of hepatitis C virus infection. J Hepatol 2011; 55: 245-264.
    • (2011) J Hepatol , vol.55 , pp. 245-264
  • 22
    • 0037371144 scopus 로고    scopus 로고
    • Prediction of treatment outcome in patients with chronic hepatitis C: significance of baseline parameters and viral dynamics during therapy
    • Berg T, Sarrazin C, Herrmann E, Hinrichsen H, Gerlach T, Zachoval R, Wiedenmann B, Hopf U, Zeuzem S. Prediction of treatment outcome in patients with chronic hepatitis C: significance of baseline parameters and viral dynamics during therapy. Hepatology 2003; 37: 600-609.
    • (2003) Hepatology , vol.37 , pp. 600-609
    • Berg, T.1    Sarrazin, C.2    Herrmann, E.3    Hinrichsen, H.4    Gerlach, T.5    Zachoval, R.6    Wiedenmann, B.7    Hopf, U.8    Zeuzem, S.9
  • 23
    • 0041822106 scopus 로고    scopus 로고
    • Early virologic response to treatment with peginterferon alfa-2b plus ribavirin in patients with chronic hepatitis C
    • Davis GL, Wong JB, McHutchison JG, Manns MP, Harvey J, Albrecht J. Early virologic response to treatment with peginterferon alfa-2b plus ribavirin in patients with chronic hepatitis C. Hepatology 2003; 38: 645-652.
    • (2003) Hepatology , vol.38 , pp. 645-652
    • Davis, G.L.1    Wong, J.B.2    McHutchison, J.G.3    Manns, M.P.4    Harvey, J.5    Albrecht, J.6
  • 24
    • 69949167624 scopus 로고    scopus 로고
    • Retreatment with pegylated interferon plus ribavirin of chronic hepatitis C non-responders to interferon plus ribavirin: a meta-analysis
    • Camma C, Cabibbo G, Bronte F, Enea M, Licata A, Attanasio M, Andriulli A, Craxi A. Retreatment with pegylated interferon plus ribavirin of chronic hepatitis C non-responders to interferon plus ribavirin: a meta-analysis. J Hepatol 2009; 51: 675-681.
    • (2009) J Hepatol , vol.51 , pp. 675-681
    • Camma, C.1    Cabibbo, G.2    Bronte, F.3    Enea, M.4    Licata, A.5    Attanasio, M.6    Andriulli, A.7    Craxi, A.8
  • 28
    • 67651083226 scopus 로고    scopus 로고
    • Hepatitis C treatment for injection drug users: a review of the available evidence
    • Hellard M, Sacks-Davis R, Gold J. Hepatitis C treatment for injection drug users: a review of the available evidence. Clin Infect Dis 2009; 49: 561-573.
    • (2009) Clin Infect Dis , vol.49 , pp. 561-573
    • Hellard, M.1    Sacks-Davis, R.2    Gold, J.3
  • 30
    • 34247895578 scopus 로고    scopus 로고
    • The hepatitis C virus life cycle as a target for new antiviral therapies
    • Pawlotsky JM, Chevaliez S, McHutchison JG. The hepatitis C virus life cycle as a target for new antiviral therapies. Gastroenterology 2007; 132: 1979-1998.
    • (2007) Gastroenterology , vol.132 , pp. 1979-1998
    • Pawlotsky, J.M.1    Chevaliez, S.2    McHutchison, J.G.3
  • 31
    • 34249024924 scopus 로고    scopus 로고
    • Replication of hepatitis C virus. Nature reviews
    • Moradpour D, Penin F, Rice CM. Replication of hepatitis C virus. Nature reviews. Microbiology 2007; 5: 453-463.
    • (2007) Microbiology , vol.5 , pp. 453-463
    • Moradpour, D.1    Penin, F.2    Rice, C.M.3
  • 32
    • 80052361810 scopus 로고    scopus 로고
    • Emerging therapies in hepatitis C: dawn of the era of the direct-acting antivirals
    • Jazwinski AB, Muir AJ. Emerging therapies in hepatitis C: dawn of the era of the direct-acting antivirals. Gastroenterol Clin North Am 2011; 40: 481-494.
    • (2011) Gastroenterol Clin North Am , vol.40 , pp. 481-494
    • Jazwinski, A.B.1    Muir, A.J.2
  • 33
    • 77953416889 scopus 로고    scopus 로고
    • New direct-acting antivirals in the development for hepatitis C virus infection
    • Pockros PJ. New direct-acting antivirals in the development for hepatitis C virus infection. Therap Adv Gastroenterol 2010; 3: 191-202.
    • (2010) Therap Adv Gastroenterol , vol.3 , pp. 191-202
    • Pockros, P.J.1
  • 34
    • 84859067322 scopus 로고    scopus 로고
    • New therapies for chronic hepatitis C infection: a systematic review of evidence from clinical trials
    • Lee LY, Tong CY, Wong T, Wilkinson M. New therapies for chronic hepatitis C infection: a systematic review of evidence from clinical trials. Int J Clin Pract 2012; 66: 342-355.
    • (2012) Int J Clin Pract , vol.66 , pp. 342-355
    • Lee, L.Y.1    Tong, C.Y.2    Wong, T.3    Wilkinson, M.4
  • 36
    • 80052456662 scopus 로고    scopus 로고
    • Boceprevir: a protease inhibitor for the treatment of chronic hepatitis C
    • Foote BS, Spooner LM, Belliveau PP. Boceprevir: a protease inhibitor for the treatment of chronic hepatitis C. Ann Pharmacother 2011; 45: 1085-1093.
    • (2011) Ann Pharmacother , vol.45 , pp. 1085-1093
    • Foote, B.S.1    Spooner, L.M.2    Belliveau, P.P.3
  • 41
    • 84858167086 scopus 로고    scopus 로고
    • Efficacy of boceprevir in prior null responders to peginterferon/ribavirin: the PROVIDE Study
    • Vierling JM. Efficacy of boceprevir in prior null responders to peginterferon/ribavirin: the PROVIDE Study. Hepatology 2011; 54 (Suppl. 1): A931.
    • (2011) Hepatology , vol.54 , Issue.SUPPL. 1
    • Vierling, J.M.1
  • 46
    • 84875076369 scopus 로고    scopus 로고
    • Clinical pharmacology of boceprevir: metabolism, excretion and drug-drug interactions. Conference on Retroviruses and Opporunistic Infections, Boston.
    • Kasserra C, Hughes E, Treitel M, Gupta S, O'Mar E. Clinical pharmacology of boceprevir: metabolism, excretion and drug-drug interactions. Conference on Retroviruses and Opporunistic Infections, Boston. 2011.
    • (2011)
    • Kasserra, C.1    Hughes, E.2    Treitel, M.3    Gupta, S.4    O'Mar, E.5
  • 48
    • 84856906043 scopus 로고    scopus 로고
    • TMC435 in combination with peginterferon and ribavirin in treatment-naïve HCV genotype 1 patients: final analysis of the PILLAR phase IIb study
    • Fried MW. TMC435 in combination with peginterferon and ribavirin in treatment-naïve HCV genotype 1 patients: final analysis of the PILLAR phase IIb study. Hepatology 2011; 54 (Suppl. 1): LB5.
    • (2011) Hepatology , vol.54 , Issue.SUPPL. 1
    • Fried, M.W.1
  • 49
    • 84863676547 scopus 로고    scopus 로고
    • Safety and antiviral activity of MK-5172, a next generation HCV NS3/4A protease inhibitor with a broad HCV genotypic activity spectrum and potent activity against known resistance mutants, in genotype-1 and -3 HCV-infected patients
    • Petry AS, Fraser IP, Van Dyck K, Nachbar RB, De Lepeleire I, Robberechts M, Han L, Palcza J, Moiseez V, Kobalava ZD, Uhle M, Wagner F, O'Mara E, Wagner JA. Safety and antiviral activity of MK-5172, a next generation HCV NS3/4A protease inhibitor with a broad HCV genotypic activity spectrum and potent activity against known resistance mutants, in genotype-1 and -3 HCV-infected patients. Hepatology 2011; 54 (Suppl. 1): 1364A.
    • (2011) Hepatology , vol.54 , Issue.SUPPL. 1
    • Petry, A.S.1    Fraser, I.P.2    Van Dyck, K.3    Nachbar, R.B.4    De Lepeleire, I.5    Robberechts, M.6    Han, L.7    Palcza, J.8    Moiseez, V.9    Kobalava, Z.D.10    Uhle, M.11    Wagner, F.12    O'Mara, E.13    Wagner, J.A.14
  • 50
    • 79958830099 scopus 로고    scopus 로고
    • Hepatitis C virus resistance to protease inhibitors
    • Halfon P, Locarnini S. Hepatitis C virus resistance to protease inhibitors. J Hepatol 2011; 55: 192-206.
    • (2011) J Hepatol , vol.55 , pp. 192-206
    • Halfon, P.1    Locarnini, S.2
  • 51
    • 84855248040 scopus 로고    scopus 로고
    • Once daily PSI-7977 plus RBV: pegylated interferon-alfa not required for complete rapid viral response in treatment-naive patients with HCV GT2 or GT3
    • Gane EJ, Stedman CA, Hyland RH, Sorensen RD, Symonds WT, Hindes R, Berrey M. Once daily PSI-7977 plus RBV: pegylated interferon-alfa not required for complete rapid viral response in treatment-naive patients with HCV GT2 or GT3. Hepatology 2011; 54 (Suppl. 1): 377A.
    • (2011) Hepatology , vol.54 , Issue.SUPPL. 1
    • Gane, E.J.1    Stedman, C.A.2    Hyland, R.H.3    Sorensen, R.D.4    Symonds, W.T.5    Hindes, R.6    Berrey, M.7
  • 52
    • 84875084161 scopus 로고    scopus 로고
    • 100% Rapid Virologic Response for PSI-7977 + Ribavirin in Genotype 1 Null Responders (ELECTRON): early Viral Decline Similar to that Observed in Genotype 1 and Genotype 2/3 Treatment-naïve Patients Conference on Retroviruses and Opporunistic Infections, Seattle. :54LB.
    • Gane E, Stedman C, Anderson J, Hyland R, Hindes R, Symonds W, Berrey M. 100% Rapid Virologic Response for PSI-7977 + Ribavirin in Genotype 1 Null Responders (ELECTRON): early Viral Decline Similar to that Observed in Genotype 1 and Genotype 2/3 Treatment-naïve Patients Conference on Retroviruses and Opporunistic Infections, Seattle. 2012:54LB.
    • (2012)
    • Gane, E.1    Stedman, C.2    Anderson, J.3    Hyland, R.4    Hindes, R.5    Symonds, W.6    Berrey, M.7
  • 54
    • 79960453114 scopus 로고    scopus 로고
    • First SVR data with the nucleoside analogue polymerase inhibitor mericitabine (RG7128) combined with peginterferon/ribavirin in treatment naïve HCV G 1 and 4 patients: interim analysis from the JUMP-C trial
    • Pockros P, Jensen D, Tsai N. First SVR data with the nucleoside analogue polymerase inhibitor mericitabine (RG7128) combined with peginterferon/ribavirin in treatment naïve HCV G 1 and 4 patients: interim analysis from the JUMP-C trial. J Hepatol 2011; 54 (Suppl. 1): S538.
    • (2011) J Hepatol , vol.54 , Issue.SUPPL. 1
    • Pockros, P.1    Jensen, D.2    Tsai, N.3
  • 56
    • 72049107298 scopus 로고    scopus 로고
    • Safety, pharmacokinetics and antiviral effect of BI 207127, a novel HCV RNA polymerase inhibitor, after 5 days oral treatment in patients with chronic hepatitis C
    • Larrey D, Benhamou Y, Lohse AW, Trepo C, Moelleken C, Bronowicki J-P. Safety, pharmacokinetics and antiviral effect of BI 207127, a novel HCV RNA polymerase inhibitor, after 5 days oral treatment in patients with chronic hepatitis C. J Hepatol 2009; 50: S383.
    • (2009) J Hepatol , vol.50
    • Larrey, D.1    Benhamou, Y.2    Lohse, A.W.3    Trepo, C.4    Moelleken, C.5    Bronowicki, J.-P.6
  • 60
    • 84858415895 scopus 로고    scopus 로고
    • Prevalence of natural polymorphisms at the HCV NS5A gene associated with resistance to daclatasvir, an NS5A inhibitor
    • Plaza Z, Soriano V, Vispo E, Del Mar Gonzalez M, Barreiro P, Seclen E, Poveda E. Prevalence of natural polymorphisms at the HCV NS5A gene associated with resistance to daclatasvir, an NS5A inhibitor. Antivir Ther 2012; 17: 921-926.
    • (2012) Antivir Ther , vol.17 , pp. 921-926
    • Plaza, Z.1    Soriano, V.2    Vispo, E.3    Del Mar Gonzalez, M.4    Barreiro, P.5    Seclen, E.6    Poveda, E.7
  • 63
    • 34548758435 scopus 로고    scopus 로고
    • Telaprevir and pegylated interferon-alpha-2a inhibit wild-type and resistant genotype 1 hepatitis C virus replication in patients
    • Kieffer TL, Sarrazin C, Miller JS, Welker MW, Forestier N, Reesink HW, Kwong AD, Zeuzem S. Telaprevir and pegylated interferon-alpha-2a inhibit wild-type and resistant genotype 1 hepatitis C virus replication in patients. Hepatology 2007; 46: 631-639.
    • (2007) Hepatology , vol.46 , pp. 631-639
    • Kieffer, T.L.1    Sarrazin, C.2    Miller, J.S.3    Welker, M.W.4    Forestier, N.5    Reesink, H.W.6    Kwong, A.D.7    Zeuzem, S.8
  • 68
    • 84875077673 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo (PLB) controlled safety and antiviral proof of concept study of miravirsen (MIR), an oligonucleotide targeting MIR-122, in treatment naïve patients with genotype 1 (GT1) chronic HCV infection. 62th American Association for the Study of Liver Diseases, San Francisco.
    • Janssen HLA. A randomized, double-blind, placebo (PLB) controlled safety and antiviral proof of concept study of miravirsen (MIR), an oligonucleotide targeting MIR-122, in treatment naïve patients with genotype 1 (GT1) chronic HCV infection. 62th American Association for the Study of Liver Diseases, San Francisco. 2011.
    • (2011)
    • Janssen, H.L.A.1
  • 69
    • 77955146829 scopus 로고    scopus 로고
    • Treatment of chronic hepatitis C using a 4-week lead-in with nitazoxanide before peginterferon plus nitazoxanide
    • Rossignol JF, Elfert A, Keeffe EB. Treatment of chronic hepatitis C using a 4-week lead-in with nitazoxanide before peginterferon plus nitazoxanide. J Clin Gastroenterol 2010; 44: 504-509.
    • (2010) J Clin Gastroenterol , vol.44 , pp. 504-509
    • Rossignol, J.F.1    Elfert, A.2    Keeffe, E.B.3
  • 72
    • 82455184210 scopus 로고    scopus 로고
    • IMO-2125, a TLR9 agonist, induces immune responses which correlate with reductions in viral load in null responder HCV patients
    • Rodriguez-Torres M, Ghalib RH, Gordon SC, Lawitz E, Patel K, Pruitt R. IMO-2125, a TLR9 agonist, induces immune responses which correlate with reductions in viral load in null responder HCV patients. Hepatology 2010; 52 (4 Suppl.): 336A.
    • (2010) Hepatology , vol.52 , Issue.4 SUPPL.
    • Rodriguez-Torres, M.1    Ghalib, R.H.2    Gordon, S.C.3    Lawitz, E.4    Patel, K.5    Pruitt, R.6
  • 77
    • 70349229380 scopus 로고    scopus 로고
    • A phase III study of the safety and efficacy of viramidine versus ribavirin in treatment-naive patients with chronic hepatitis C: ViSER1 results
    • Benhamou Y, Afdhal NH, Nelson DR, Shiffman ML, Halliman DG, Heise J, Chun E, Pockros PJ. A phase III study of the safety and efficacy of viramidine versus ribavirin in treatment-naive patients with chronic hepatitis C: ViSER1 results. Hepatology 2009; 50: 717-726.
    • (2009) Hepatology , vol.50 , pp. 717-726
    • Benhamou, Y.1    Afdhal, N.H.2    Nelson, D.R.3    Shiffman, M.L.4    Halliman, D.G.5    Heise, J.6    Chun, E.7    Pockros, P.J.8
  • 78
    • 71149099686 scopus 로고    scopus 로고
    • Safety and efficacy of viramidine versus ribavirin in ViSER2: randomized, double-blind study in therapy-naive hepatitis C patients
    • Marcellin P, Gish RG, Gitlin N, Heise J, Halliman DG, Chun E, Rodriguez-Torres M. Safety and efficacy of viramidine versus ribavirin in ViSER2: randomized, double-blind study in therapy-naive hepatitis C patients. J Hepatol 2010; 52: 32-38.
    • (2010) J Hepatol , vol.52 , pp. 32-38
    • Marcellin, P.1    Gish, R.G.2    Gitlin, N.3    Heise, J.4    Halliman, D.G.5    Chun, E.6    Rodriguez-Torres, M.7
  • 79
    • 84857395452 scopus 로고    scopus 로고
    • Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders
    • Chayama K, Takahashi S, Toyota J, Karino Y, Ikeda K, Ishikawa H, Watanabe H, McPhee F, Hughes E, Kumada H. Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders. Hepatology 2012; 55: 742-748.
    • (2012) Hepatology , vol.55 , pp. 742-748
    • Chayama, K.1    Takahashi, S.2    Toyota, J.3    Karino, Y.4    Ikeda, K.5    Ishikawa, H.6    Watanabe, H.7    McPhee, F.8    Hughes, E.9    Kumada, H.10
  • 81
    • 52049088979 scopus 로고    scopus 로고
    • Current approaches to HCV infection in current and former injection drug users
    • Grebely J, deVlaming S, Duncan F, Viljoen M, Conway B. Current approaches to HCV infection in current and former injection drug users. J Addict Dis 2008; 27: 25-35.
    • (2008) J Addict Dis , vol.27 , pp. 25-35
    • Grebely, J.1    deVlaming, S.2    Duncan, F.3    Viljoen, M.4    Conway, B.5
  • 83
    • 79956066416 scopus 로고    scopus 로고
    • Can antiviral therapy for hepatitis C reduce the prevalence of HCV among injecting drug user populations? A modelling analysis of its prevention utility
    • Martin NK, Vickerman P, Foster GR, Hutchinson S, Goldberg D, Hickman M. Can antiviral therapy for hepatitis C reduce the prevalence of HCV among injecting drug user populations? A modelling analysis of its prevention utility. J Hepatol 2011; 54: 1137-1144.
    • (2011) J Hepatol , vol.54 , pp. 1137-1144
    • Martin, N.K.1    Vickerman, P.2    Foster, G.R.3    Hutchinson, S.4    Goldberg, D.5    Hickman, M.6
  • 84
    • 65449136656 scopus 로고    scopus 로고
    • Diagnosis, management, and treatment of hepatitis C: an update
    • Ghany MG, Strader DB, Thomas DL, Seeff LB. Diagnosis, management, and treatment of hepatitis C: an update. Hepatology 2009; 49: 1335-1374.
    • (2009) Hepatology , vol.49 , pp. 1335-1374
    • Ghany, M.G.1    Strader, D.B.2    Thomas, D.L.3    Seeff, L.B.4
  • 89
    • 84856897317 scopus 로고    scopus 로고
    • High sustained virological response (SVR) rate after danoprevir for only 14 days associated with PEG-interferon alfa-2a and ribavirin in treatment-naive chronic HCV genotype 1 patients
    • Larrey P, Carenco C, Guyader D, Boyer N, Benhamou Y, Daniélou H, Pageaux G-P, Rouzier R, Marcellin P. High sustained virological response (SVR) rate after danoprevir for only 14 days associated with PEG-interferon alfa-2a and ribavirin in treatment-naive chronic HCV genotype 1 patients. J Hepatol 2011; 54 (Suppl. 1): S481.
    • (2011) J Hepatol , vol.54 , Issue.SUPPL. 1
    • Larrey, P.1    Carenco, C.2    Guyader, D.3    Boyer, N.4    Benhamou, Y.5    Daniélou, H.6    Pageaux, G.-P.7    Rouzier, R.8    Marcellin, P.9


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