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Volumn 32, Issue SUPPL. 1, 2012, Pages 113-119

Future treatment of patients with HCV cirrhosis

Author keywords

Boceprevir; Cirrhosis; Decompensated cirrhosis; eRVR; Genotype 1; HCV; RVR; SVR; Telaprevir

Indexed keywords

BOCEPREVIR; PEGINTERFERON; RIBAVIRIN; TELAPREVIR;

EID: 84855221079     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2011.02702.x     Document Type: Review
Times cited : (24)

References (37)
  • 1
    • 77952704228 scopus 로고    scopus 로고
    • Sustained virologic response prevents the development of esophageal varices in compensated, Child-Pugh class A hepatitis C virus-induced cirrhosis. A 12-year prospective follow-up study
    • Bruno S, Crosignani A, Facciotto C, et al. Sustained virologic response prevents the development of esophageal varices in compensated, Child-Pugh class A hepatitis C virus-induced cirrhosis. A 12-year prospective follow-up study. Hepatology 2010; 51: 2069-76.
    • (2010) Hepatology , vol.51 , pp. 2069-2076
    • Bruno, S.1    Crosignani, A.2    Facciotto, C.3
  • 2
    • 84856208416 scopus 로고    scopus 로고
    • Pegylated interferon-a2a plus ribavirin for chronic hepatitis C in a real-life setting: the Hepatys French cohort (2003-2007)
    • 103851/IMP1935.
    • Bourliere M, Ouzan D, Rosenheim M, et al. Pegylated interferon-a2a plus ribavirin for chronic hepatitis C in a real-life setting: the Hepatys French cohort (2003-2007). Antivir Ther 2011; 103851/IMP1935.
    • (2011) Antivir Ther
    • Bourliere, M.1    Ouzan, D.2    Rosenheim, M.3
  • 3
    • 79951545875 scopus 로고    scopus 로고
    • A review of the treatment of chronic hepatitis C virus infection in cirrhosis
    • Vezali E, Aghemo A, Colombo M. A review of the treatment of chronic hepatitis C virus infection in cirrhosis. Clin Ther 2010; 32: 2117-38.
    • (2010) Clin Ther , vol.32 , pp. 2117-2138
    • Vezali, E.1    Aghemo, A.2    Colombo, M.3
  • 4
    • 0030744373 scopus 로고    scopus 로고
    • Effectiveness of interferon alfa on incidence of hepatocellular carcinoma and decompensation in cirrhosis type C. European Concerted Action on Viral Hepatitis (EUROHEP)
    • Fattovich G, Giustina G, Degos F, et al. Effectiveness of interferon alfa on incidence of hepatocellular carcinoma and decompensation in cirrhosis type C. European Concerted Action on Viral Hepatitis (EUROHEP). J Hepatol 1997; 27: 201-5.
    • (1997) J Hepatol , vol.27 , pp. 201-205
    • Fattovich, G.1    Giustina, G.2    Degos, F.3
  • 5
    • 0032997086 scopus 로고    scopus 로고
    • Treatment of hepatitis C virus-related cirrhosis: a randomized, controlled trial of interferon alfa-2b versus no treatment
    • Valla DC, Chevallier M, Marcellin P, et al. Treatment of hepatitis C virus-related cirrhosis: a randomized, controlled trial of interferon alfa-2b versus no treatment. Hepatology 1999; 29: 1870-5.
    • (1999) Hepatology , vol.29 , pp. 1870-1875
    • Valla, D.C.1    Chevallier, M.2    Marcellin, P.3
  • 6
    • 0034619980 scopus 로고    scopus 로고
    • Peginterferon alfa-2a in patients with chronic hepatitis C and cirrhosis
    • Heathcote EJ, Shiffman ML, Cooksley WG, et al. Peginterferon alfa-2a in patients with chronic hepatitis C and cirrhosis. N Engl J Med 2000; 343: 1673-80.
    • (2000) N Engl J Med , vol.343 , pp. 1673-1680
    • Heathcote, E.J.1    Shiffman, M.L.2    Cooksley, W.G.3
  • 7
    • 33750078958 scopus 로고    scopus 로고
    • HCV-related advanced fibrosis/cirrhosis: randomized controlled trial of pegylated interferon alpha-2a and ribavirin
    • Helbling B, Jochum W, Stamenic I, et al. HCV-related advanced fibrosis/cirrhosis: randomized controlled trial of pegylated interferon alpha-2a and ribavirin. J Viral Hepat 2006; 13: 762-9.
    • (2006) J Viral Hepat , vol.13 , pp. 762-769
    • Helbling, B.1    Jochum, W.2    Stamenic, I.3
  • 8
    • 33751009135 scopus 로고    scopus 로고
    • Peginterferon alpha-2b plus ribavirin for treatment of chronic hepatitis C with severe fibrosis: a multicentre randomized controlled trial comparing two doses of peginterferon alpha-2b
    • Abergel A, Hezode C, Leroy V, et al. Peginterferon alpha-2b plus ribavirin for treatment of chronic hepatitis C with severe fibrosis: a multicentre randomized controlled trial comparing two doses of peginterferon alpha-2b. J Viral Hepat 2006; 13: 811-20.
    • (2006) J Viral Hepat , vol.13 , pp. 811-820
    • Abergel, A.1    Hezode, C.2    Leroy, V.3
  • 9
    • 34548227085 scopus 로고    scopus 로고
    • Peg-interferon alone or combined with ribavirin in HCV cirrhosis with portal hypertension: a randomized controlled trial
    • Di Marco V, Almasio PL, Ferraro D, et al. Peg-interferon alone or combined with ribavirin in HCV cirrhosis with portal hypertension: a randomized controlled trial. J Hepatol 2007; 47: 484-91.
    • (2007) J Hepatol , vol.47 , pp. 484-491
    • Di Marco, V.1    Almasio, P.L.2    Ferraro, D.3
  • 10
    • 49949115600 scopus 로고    scopus 로고
    • Pegylated interferon-alpha2b plus ribavirin: an efficacious and well-tolerated treatment regimen for patients with hepatitis C virus related histologically proven cirrhosis
    • Roffi L, Colloredo G, Pioltelli P, et al. Pegylated interferon-alpha2b plus ribavirin: an efficacious and well-tolerated treatment regimen for patients with hepatitis C virus related histologically proven cirrhosis. Antivir Ther 2008; 13: 663-73.
    • (2008) Antivir Ther , vol.13 , pp. 663-673
    • Roffi, L.1    Colloredo, G.2    Pioltelli, P.3
  • 11
    • 70449417617 scopus 로고    scopus 로고
    • Predictive value of on-treatment response during full-dose antiviral therapy of patients with hepatitis C virus cirrhosis and portal hypertension
    • Giannini EG, Basso M, Savarino V, Picciotto A. Predictive value of on-treatment response during full-dose antiviral therapy of patients with hepatitis C virus cirrhosis and portal hypertension. J Intern Med 2009; 266: 537-46.
    • (2009) J Intern Med , vol.266 , pp. 537-546
    • Giannini, E.G.1    Basso, M.2    Savarino, V.3    Picciotto, A.4
  • 12
    • 68549136610 scopus 로고    scopus 로고
    • The pattern of pegylated interferon-alpha2b and ribavirin treatment failure in cirrhotic patients depends on hepatitis C virus genotype
    • Aghemo A, Rumi MG, Monico S, et al. The pattern of pegylated interferon-alpha2b and ribavirin treatment failure in cirrhotic patients depends on hepatitis C virus genotype. Antivir Ther 2009; 14: 577-84.
    • (2009) Antivir Ther , vol.14 , pp. 577-584
    • Aghemo, A.1    Rumi, M.G.2    Monico, S.3
  • 13
    • 72249083270 scopus 로고    scopus 로고
    • Randomized study of peginterferon-alpha2a plus ribavirin vs peginterferon-alpha2b plus ribavirin in chronic hepatitis C
    • Rumi MG, Aghemo A, Prati GM, et al. Randomized study of peginterferon-alpha2a plus ribavirin vs peginterferon-alpha2b plus ribavirin in chronic hepatitis C. Gastroenterology 2010; 138: 108-15.
    • (2010) Gastroenterology , vol.138 , pp. 108-115
    • Rumi, M.G.1    Aghemo, A.2    Prati, G.M.3
  • 14
    • 77956268664 scopus 로고    scopus 로고
    • Low virological response and high relapse rates in hepatitis C genotype 1 patients with advanced fibrosis despite adequate therapeutic dosing
    • Cheng WS, Roberts SK, McCaughan G, et al. Low virological response and high relapse rates in hepatitis C genotype 1 patients with advanced fibrosis despite adequate therapeutic dosing. J Hepatol 2010; 53: 616-23.
    • (2010) J Hepatol , vol.53 , pp. 616-623
    • Cheng, W.S.1    Roberts, S.K.2    McCaughan, G.3
  • 15
    • 75449106958 scopus 로고    scopus 로고
    • Efficacy and safety of peginterferon alfa-2a (40KD) plus ribavirin in hepatitis C patients with advanced fibrosis and cirrhosis
    • Bruno S, Shiffman ML, Roberts SK, et al. Efficacy and safety of peginterferon alfa-2a (40KD) plus ribavirin in hepatitis C patients with advanced fibrosis and cirrhosis. Hepatology 2010; 51: 388-97.
    • (2010) Hepatology , vol.51 , pp. 388-397
    • Bruno, S.1    Shiffman, M.L.2    Roberts, S.K.3
  • 16
    • 1542378867 scopus 로고    scopus 로고
    • Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose
    • Hadziyannis SJ, Sette H Jr, Morgan TR, et al. Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose. Ann Intern Med 2004; 140: 346-55.
    • (2004) Ann Intern Med , vol.140 , pp. 346-355
    • Hadziyannis, S.J.1    Sette Jr., H.2    Morgan, T.R.3
  • 17
    • 19944428400 scopus 로고    scopus 로고
    • Antiviral therapy for cirrhotic hepatitis C: association with reduced hepatocellular carcinoma development and improved survival
    • Shiratori Y, Ito Y, Yokosuka O, et al. Antiviral therapy for cirrhotic hepatitis C: association with reduced hepatocellular carcinoma development and improved survival. Ann Intern Med 2005; 142: 105-14.
    • (2005) Ann Intern Med , vol.142 , pp. 105-114
    • Shiratori, Y.1    Ito, Y.2    Yokosuka, O.3
  • 18
    • 33745838657 scopus 로고    scopus 로고
    • Long-term effect of interferon alpha-2b plus ribavirin therapy on incidence of hepatocellular carcinoma in patients with hepatitis C virus-related cirrhosis
    • Hung CH, Lee CM, Lu SN, et al. Long-term effect of interferon alpha-2b plus ribavirin therapy on incidence of hepatocellular carcinoma in patients with hepatitis C virus-related cirrhosis. J Viral Hepat 2006; 13: 409-14.
    • (2006) J Viral Hepat , vol.13 , pp. 409-414
    • Hung, C.H.1    Lee, C.M.2    Lu, S.N.3
  • 19
    • 38449091418 scopus 로고    scopus 로고
    • Sustained virologic response and clinical outcomes in patients with chronic hepatitis C and advanced fibrosis
    • Veldt BJ, Heathcote EJ, Wedemeyer H, et al. Sustained virologic response and clinical outcomes in patients with chronic hepatitis C and advanced fibrosis. Ann Intern Med 2007; 147: 677-84.
    • (2007) Ann Intern Med , vol.147 , pp. 677-684
    • Veldt, B.J.1    Heathcote, E.J.2    Wedemeyer, H.3
  • 20
    • 34247570948 scopus 로고    scopus 로고
    • Development of hepatocellular carcinoma in patients with chronic hepatitis C who had a sustained virological response to interferon therapy: a multicenter, retrospective cohort study of 1124 patients
    • Kobayashi S, Takeda T, Enomoto M, et al. Development of hepatocellular carcinoma in patients with chronic hepatitis C who had a sustained virological response to interferon therapy: a multicenter, retrospective cohort study of 1124 patients. Liver Int 2007; 27: 186-91.
    • (2007) Liver Int , vol.27 , pp. 186-191
    • Kobayashi, S.1    Takeda, T.2    Enomoto, M.3
  • 21
    • 84855240590 scopus 로고    scopus 로고
    • Hyporesponsiveness to pegifnalpha2b plus ribavirin in patients with hepatitis C-related advanced fibrosis
    • E-pub ahead of print.
    • Prati GM, Aghemo A, Rumi MG, et al. Hyporesponsiveness to pegifnalpha2b plus ribavirin in patients with hepatitis C-related advanced fibrosis. J Hepatol 2011; E-pub ahead of print.
    • (2011) J Hepatol
    • Prati, G.M.1    Aghemo, A.2    Rumi, M.G.3
  • 22
    • 68249154875 scopus 로고    scopus 로고
    • Peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection
    • McHutchison JG, Lawitz EJ, Shiffman ML, et al. Peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection. N Engl J Med 2009; 361: 580-93.
    • (2009) N Engl J Med , vol.361 , pp. 580-593
    • McHutchison, J.G.1    Lawitz, E.J.2    Shiffman, M.L.3
  • 23
    • 0031041924 scopus 로고    scopus 로고
    • Morbidity and mortality in compensated cirrhosis type C: a retrospective follow-up study of 384 patients
    • Fattovich G, Giustina G, Degos F, et al. Morbidity and mortality in compensated cirrhosis type C: a retrospective follow-up study of 384 patients. Gastroenterology 1997; 112: 463-72.
    • (1997) Gastroenterology , vol.112 , pp. 463-472
    • Fattovich, G.1    Giustina, G.2    Degos, F.3
  • 24
    • 10744234013 scopus 로고    scopus 로고
    • Antiviral therapy of patients with decompensated cirrhosis to prevent recurrence of hepatitis C after liver transplantation
    • Forns X, Garcia-Retortillo M, Serrano T, et al. Antiviral therapy of patients with decompensated cirrhosis to prevent recurrence of hepatitis C after liver transplantation. J Hepatol 2003; 39: 389-96.
    • (2003) J Hepatol , vol.39 , pp. 389-396
    • Forns, X.1    Garcia-Retortillo, M.2    Serrano, T.3
  • 25
    • 33845647232 scopus 로고    scopus 로고
    • Peginterferon alfa-2b and ribavirin in patients with hepatitis C virus and decompensated cirrhosis: a controlled study
    • Iacobellis A, Siciliano M, Perri F, et al. Peginterferon alfa-2b and ribavirin in patients with hepatitis C virus and decompensated cirrhosis: a controlled study. J Hepatol 2007; 46: 206-12.
    • (2007) J Hepatol , vol.46 , pp. 206-212
    • Iacobellis, A.1    Siciliano, M.2    Perri, F.3
  • 26
    • 48049111621 scopus 로고    scopus 로고
    • Treatment of chronic hepatitis C virus infection with pegylated interferon and ribavirin in cirrhotic patients awaiting liver transplantation
    • Annicchiarico BE, Siciliano M, Avolio AW, et al. Treatment of chronic hepatitis C virus infection with pegylated interferon and ribavirin in cirrhotic patients awaiting liver transplantation. Transplant Proc 2008; 40: 1918-20.
    • (2008) Transplant Proc , vol.40 , pp. 1918-1920
    • Annicchiarico, B.E.1    Siciliano, M.2    Avolio, A.W.3
  • 27
    • 79955060448 scopus 로고    scopus 로고
    • PHOENIX: a randomized controlled trial of peginterferon alfa-2a plus ribavirin as a prophylactic treatment after liver transplantation for hepatitis C virus
    • Bzowej N, Nelson DR, Terrault NA, et al. PHOENIX: a randomized controlled trial of peginterferon alfa-2a plus ribavirin as a prophylactic treatment after liver transplantation for hepatitis C virus. Liver Transpl 2011; 17: 528-38.
    • (2011) Liver Transpl , vol.17 , pp. 528-538
    • Bzowej, N.1    Nelson, D.R.2    Terrault, N.A.3
  • 28
    • 67649880240 scopus 로고    scopus 로고
    • Sustained virological responses following standard anti-viral therapy in decompensated HCV-infected cirrhotic patients
    • Iacobellis A, Siciliano M, Annicchiarico BE, et al. Sustained virological responses following standard anti-viral therapy in decompensated HCV-infected cirrhotic patients. Aliment Pharmacol Ther 2009; 30: 146-53.
    • (2009) Aliment Pharmacol Ther , vol.30 , pp. 146-153
    • Iacobellis, A.1    Siciliano, M.2    Annicchiarico, B.E.3
  • 29
    • 42949108594 scopus 로고    scopus 로고
    • Safety, tolerability, and efficacy of pegylated-interferon alfa-2a plus ribavirin in HCV-related decompensated cirrhotics
    • Tekin F, Gunsar F, Karasu Z, Akarca U, Ersoz G. Safety, tolerability, and efficacy of pegylated-interferon alfa-2a plus ribavirin in HCV-related decompensated cirrhotics. Aliment Pharmacol Ther 2008; 27: 1081-5.
    • (2008) Aliment Pharmacol Ther , vol.27 , pp. 1081-1085
    • Tekin, F.1    Gunsar, F.2    Karasu, Z.3    Akarca, U.4    Ersoz, G.5
  • 30
    • 61749085030 scopus 로고    scopus 로고
    • Antiviral therapy increases the risk of bacterial infections in HCV-infected cirrhotic patients awaiting liver transplantation: A retrospective study
    • Carrion JA, Martinez-Bauer E, Crespo G, et al. Antiviral therapy increases the risk of bacterial infections in HCV-infected cirrhotic patients awaiting liver transplantation: A retrospective study. J Hepatol 2009; 50: 719-28.
    • (2009) J Hepatol , vol.50 , pp. 719-728
    • Carrion, J.A.1    Martinez-Bauer, E.2    Crespo, G.3
  • 31
    • 79953173221 scopus 로고    scopus 로고
    • Boceprevir for untreated chronic HCV genotype 1 infection
    • Poordad F, McCone J Jr, Bacon BR, et al. Boceprevir for untreated chronic HCV genotype 1 infection. N Engl J Med 2011; 364: 1195-206.
    • (2011) N Engl J Med , vol.364 , pp. 1195-1206
    • Poordad, F.1    McCone Jr., J.2    Bacon, B.R.3
  • 32
    • 79959438789 scopus 로고    scopus 로고
    • Telaprevir for previously untreated chronic hepatitis C virus infection
    • Jacobson IM, McHutchison JG, Dusheiko G, et al. Telaprevir for previously untreated chronic hepatitis C virus infection. N Engl J Med 2011; 364: 2405-16.
    • (2011) N Engl J Med , vol.364 , pp. 2405-2416
    • Jacobson, I.M.1    McHutchison, J.G.2    Dusheiko, G.3
  • 33
    • 79953176289 scopus 로고    scopus 로고
    • Boceprevir for previously treated chronic HCV genotype 1 infection
    • Bacon BR, Gordon SC, Lawitz E, et al. Boceprevir for previously treated chronic HCV genotype 1 infection. N Engl J Med 2011; 364: 1207-17.
    • (2011) N Engl J Med , vol.364 , pp. 1207-1217
    • Bacon, B.R.1    Gordon, S.C.2    Lawitz, E.3
  • 34
    • 79959381354 scopus 로고    scopus 로고
    • Telaprevir for retreatment of HCV infection
    • Zeuzem S, Andreone P, Pol S, et al. Telaprevir for retreatment of HCV infection. N Engl J Med 2011; 364: 2417-28.
    • (2011) N Engl J Med , vol.364 , pp. 2417-2428
    • Zeuzem, S.1    Andreone, P.2    Pol, S.3
  • 35
    • 80053541770 scopus 로고    scopus 로고
    • Boceprevir in addition to standard of care enhanced SVR in hepatitis C virus genotype-1 with advanced fibrosis/cirrhosis: subgroup analysis of SPRINT-2 and RESPOND-2 studies
    • abstract
    • Bruno S, Vierling J, Esteban R, et al. Boceprevir in addition to standard of care enhanced SVR in hepatitis C virus genotype-1 with advanced fibrosis/cirrhosis: subgroup analysis of SPRINT-2 and RESPOND-2 studies. J Hepatol 2011; 54: S4 (abstract).
    • (2011) J Hepatol , vol.54
    • Bruno, S.1    Vierling, J.2    Esteban, R.3
  • 36
    • 80052826527 scopus 로고    scopus 로고
    • Response-guided telaprevir combination treatment for hepatitis C virus infection
    • Sherman KE, Flamm SL, Afdhal NH, et al. Response-guided telaprevir combination treatment for hepatitis C virus infection. N Engl J Med 2011; 365: 1014-24.
    • (2011) N Engl J Med , vol.365 , pp. 1014-1024
    • Sherman, K.E.1    Flamm, S.L.2    Afdhal, N.H.3
  • 37
    • 84855218717 scopus 로고    scopus 로고
    • Efficacy and safety of telaprevir-based regimen in cirrhotic patients with HCV genotype-1 and prior peginterferon/ribavirin treatment failure: subanalysis of the REALIZE phase III study
    • abstract
    • Pol S, Roberts SK, Andreone P, et al. Efficacy and safety of telaprevir-based regimen in cirrhotic patients with HCV genotype-1 and prior peginterferon/ribavirin treatment failure: subanalysis of the REALIZE phase III study. Hepatology 2011; 54 suppl: 374A. (abstract).
    • (2011) Hepatology , vol.54 , Issue.SUPPL.
    • Pol, S.1    Roberts, S.K.2    Andreone, P.3


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