Advanced oxidation protein products induce cardiomyocyte death via Nox2/Rac1/superoxide-dependent TRAF3IP2/JNK signaling

Free Radical Biology and Medicine

Volumn 60, Issue , 2013, Pages 125-135

  Valente, Anthony J ^a   Yoshida, Tadashi ^b   Clark, Robert A ^a   Delafontaine, Patrice ^b   Siebenlist, Ulrich ^c   Chandrasekar, Bysani ^b,d  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

AOPPs; Cell death; Free radicals; Myocardial injury; Oxidative stress; TRAF3IP2

Indexed keywords

ADVANCED OXIDATION PROTEIN PRODUCT; ALBUMIN; CYTOCHROME C; HYDROGEN PEROXIDE; PROTEIN BAX; PROTEIN BCL XL; RAC1 PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; XANTHINE OXIDASE;

ALBUMIN BLOOD LEVEL; ANIMAL CELL; APOPTOSIS; ARTICLE; CARDIOVASCULAR RISK; CELL DEATH; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; HEART MUSCLE CELL; HEART MUSCLE INJURY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADVANCED OXIDATION PROTEIN PRODUCTS; ANIMALS; BLOOD PROTEINS; CELL DEATH; HALOGENATION; MAP KINASE KINASE 4; MEMBRANE GLYCOPROTEINS; MICE; MYOCYTES, CARDIAC; NADPH OXIDASE; NEUROPEPTIDES; OXIDANTS; OXIDATION-REDUCTION; OXIDATIVE STRESS; RAC1 GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; SUPEROXIDES;

EID: 84875067494     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.02.012     Document Type: Article

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