The pro-atherogenic effects of macrophages are reduced upon formation of a complex between C-reactive protein and lysophosphatidylcholine

Journal of Inflammation (United Kingdom)

Volumn 9, Issue , 2012, Pages

  Chang, Mi Kyung ^a,c   Hartvigsen, Karsten ^a   Ryu, Jewon ^b   Kim, Yuna ^b   Han, Ki Hoon ^b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b University of Ulsan College of Medicine   (South Korea)

^c Samsung Boramae Omni Tower   (South Korea)

Author keywords

C reactive protein; Foam cells; Lysophosphatidylcholine; Macrophages

Indexed keywords

ABC TRANSPORTER A1; C REACTIVE PROTEIN; CALCIUM; CD36 ANTIGEN; CELL PROTEIN; FC RECEPTOR IIA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYSOPHOSPHATIDYLCHOLINE; OXIDIZED LOW DENSITY LIPOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN PPRE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANTIBODY LABELING; ARTICLE; ATHEROGENESIS; CHEMOLUMINESCENCE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOASSAY; INHIBITION KINETICS; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; MACROPHAGE MIGRATION; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; TRANSCRIPTION INITIATION; UPREGULATION;

EID: 84868222848     PISSN: None     EISSN: 14769255     Source Type: Journal    
DOI: 10.1186/1476-9255-9-42     Document Type: Article

References (38)

1. Inflammation and atherosclerosis. Libby P, Ridker PM, Maseri A, Circulation 2002 105 1135 1143 10.1161/hc0902.104353 11877368 (Pubitemid 34212626)
2. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. Ridker PM, Hennekens CH, Buring JE, Rifai N, N Engl J Med 2000 342 836 843 10.1056/NEJM200003233421202 10733371 (Pubitemid 30165206)
3. The prognostic value of C-reactive protein and serum amyloid A protein in severe unstable angina. Liuzzo G, Biasucci LM, Gallimore JR, N Engl J Med 1994 331 417 424 10.1056/NEJM199408183310701 7880233 (Pubitemid 24247397)
4. C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance. Sun H, Koike T, Ichikawa T, Hatakeyama K, Shiomi M, Zhang B, Kitajima S, Morimoto M, Watanabe T, Asada Y, et al. Am J Pathol 2005 167 1139 1148 10.1016/S0002-9440(10)61202-3 16192648 (Pubitemid 41416264)
5. Sources of CRP in atherosclerotic lesions. Jialal I, Devaraj S, Singh U, Am J Pathol 2005 168 1054 1055
6. Binding and internalization of C-Reactive protein by Fcgamma receptors on human aortic endothelial cells mediates biological effects. Devaraj S, Du Clos TW, Jialal I, Arterio Throm Vasc Biol 2005 26 1359 1363 (Pubitemid 40923352)
7. Is C-reactive protein an innocent bystander or proatherogenic culprit? C-reactive protein promotes atherothrombosis. Verma S, Devaraj S, Jialal I, Circulation 2006 113 2135 2150 16671184
8. C-reactive protein binds to both oxidized LDL and apoptotic cells through recognition of a common ligand: phosphorylcholine of oxidized phospholipids. Chang MK, Binder CJ, Torzewski M, Witztum JL, Proc Natl Acad Sci USA 2002 99 13043 13048 10.1073/pnas.192399699 12244213
9. Chemistry and pathophysiology of oxidation of LDL. Esterbauer H, Ramos P, Rev Physiol Biochem Pharmacol 1996 127 31 64 10.1007/BFb0048264 8533011
10. Hydrolysis of phosphatidylcholine during LDL oxidation is mediated by platelet-activating factor acetylhydrolase. Steinbrecher UP, Pritchard PH, J Lipid Res 1989 30 305 315 2723538 (Pubitemid 19082060)
11. Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids. Steinbrecher UP, Parthasarathy S, Leake DS, Witztum JL, Steinberg D, Proc Natl Acad Sci USA 1984 81 3883 3887 10.1073/pnas.81.12.3883 6587396 (Pubitemid 14087823)
12. Lysophosphatidylcholine concentrations and metabolism in aortic intima plus inner media: effect of nutritionally induced atherosclerosis. Portman OW, Alexander M, J Lipid Res 1969 10 158 165 4238547
13. Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man. Yla-Herttuala S, Palinski W, Rosenfeld ME, Parthasarathy S, Carew TE, Butler S, Witztum JL, Steinberg D, J Clin Invest 1989 84 1086 1095 10.1172/JCI114271 2794046 (Pubitemid 19247577)
14. Lipoprotein-associated phospholipase A2 as a target of therapy. Macphee CH, Nelson JJ, Zalewski A, Curr Opin Lipidol 2005 16 442 446 10.1097/01.mol.0000174155.61307.5f 15990594
15. Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator-activated receptor gamma. Han KH, Chang MK, Boullier A, Green SR, Li A, Glass CK, Quehenberger O, J Clin Invest 2000 106 793 802 10.1172/JCI10052 10995790
16. C-reactive protein promotes monocyte chemoattractant protein-1-mediated chemotaxis through upregulating CC chemokine receptor 2 expression in human monocytes. Han KH, Hong KH, Park JH, Ko J, Kang DH, Choi KJ, Hong MK, Park SW, Park SJ, Circulation 2004 109 2566 2571 10.1161/01.CIR.0000131160.94926.6E 15136507 (Pubitemid 38720558)
17. Cyclopentenone prostaglandins induce endothelial cell apoptosis independent of the peroxisome proliferator-activatied receptor. Erl W, Weber C, Zernecke A, Neuzil J, Vosseler CA, Kim HJ, Weber PC, Eur J Immunol 2004 34 241 250 10.1002/eji.200324053 14971050 (Pubitemid 38111540)
18. Calcium ion binding regions in C-reactive protein: location and regulation of conformational changes. Mullenix MC, Mortensen RF, Mol Immunol 1994 31 615 622 10.1016/0161-5890(94)90169-4 8196672 (Pubitemid 24175029)
19. Mapping the binding areas of human C-reactive protein for phosphorylcholine and polycationic compounds. Lee RT, Takagahara I, Lee YC, J Biol Chem 2002 277 225 232 11684681
20. Analysis of binding sites in human C-reactive protein for Fc{gamma}RI, Fc{gamma}RIIA, and C1q by site-directed mutagenesis. Bang R, Marnell L, Mold C, Stein MP, Clos KT, Chivington-Buck C, Clos TW, J Biol Chem 2005 280 25095 25102 10.1074/jbc.M504782200 15878871 (Pubitemid 40934601)
21. Dissociation and subunit rearrangement of membrane-bound human C-reactive proteins. Wang H, Sui S, Biochem Biophys Res Commun 2001 288 75 79 10.1006/bbrc.2001.5733 11594754 (Pubitemid 32999727)
22. SHIP-2 inositol phosphatase is inducibly expressed in human monocytes and serves to regulate Fcgamma receptor-mediated signaling. Pengal RA, Ganesan LP, Fang H, Marsh CB, Anderson CL, Tridandapani S, J Biol Chem 2003 278 22657 22663 10.1074/jbc.M302907200 12690104 (Pubitemid 36830324)
23. FcepsilonRI- and Fcgamma receptor-mediated production of reactive oxygen species by mast cells is lipoxygenase- and cyclooxygenase-dependent and NADPH oxidase-independent. Swindle EJ, Coleman JW, DeLeo FR, Metcalfe DD, J Immunol 2007 179 7059 7071 17982097
24. Cholesterol efflux from macrophages and other cells. von Eckardstein A, Curr Opin Lipidol 1996 7 308 319 10.1097/00041433-199610000-00009 8937522 (Pubitemid 26372451)
25. Roles of ATP binding cassette transporters A1 and G1, scavenger receptor BI and membrane lipid domains in cholesterol export from macrophages. Jessup W, Gelissen IC, Gaus K, Kritharides L, Curr Opin Lipidol 2006 17 247 257 10.1097/01.mol.0000226116.35555.eb 16680029 (Pubitemid 43786058)
26. Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: evidence that oxidation-specific epitopes mediate macrophage recognition. Chang MK, Bergmark C, Laurila A, Horkko S, Han KH, Friedman P, Dennis EA, Witztum JL, Proc Natl Acad Sci USA 1999 96 6353 6358 10.1073/pnas.96.11.6353 10339591 (Pubitemid 29256669)
27. C-reactive protein-bound enzymatically modified low-density lipoprotein does not transform macrophages into foam cells. Singh SK, Suresh MV, Prayther DC, Moorman JP, Rusinol AE, Agrawal A, J Immunol 2008 180 4316 4322 18322245
28. C-reactive protein and annexin A5 bind to distinct sites of negatively charged phospholipids present in oxidized low-density lipoprotein. van Tits L, de Graaf J, Toenhake H, van Heerde W, Stalenhoef A, Arterio Throm Vasc Biol 2005 25 717 722 10.1161/01.ATV.0000157979.51673.2c (Pubitemid 40463859)
29. Human C-reactive protein promotes oxidized low density lipoprotein uptake and matrix metalloproteinase-9 release in Wistar rats. Singh U, Dasu MR, Yancey PG, Afify A, Devaraj S, Jialal I, J Lipid Res 2008 49 1015 1023 10.1194/jlr.M700535-JLR200 18245817
30. CD36 and macrophages in atherosclerosis. Collot-Teixeira S, Martin J, McDermott-Roe C, Poston R, McGregor JL, Cardiovasc Res 2007 75 468 477 10.1016/j.cardiores.2007.03.010 17442283 (Pubitemid 47080960)
31. Human C-reactive protein slows atherosclerosis development in a mouse model with human-like hypercholesterolemia. Kovacs A, Tornvall P, Nilsson R, Tegner J, Hamsten A, Bjorkegren J, Proc Natl Acad Sci USA 2007 104 13768 13773 10.1073/pnas.0706027104 17702862 (Pubitemid 350003395)
32. Increased expression and activity of MMP-9 in C-reactive protein- induced human THP-1 mononuclear cells is related to activation of nuclear factor kappa-B. Sheng F, Cheng L, Zeng Q, Gao W, J Huazhong Univ Sci Technolog Med Sci 2009 29 399 403 10.1007/s11596-009-0401-0 19662350
33. C-reactive protein promotes adhesion of monocytes to endothelial cells via NADPH oxidase-mediated oxidative stress. Huang X, Zhang J, Liu J, Sun L, Zhao H, Lu Y, Wang J, Li J, J Cell Biochem 2012 113 857 867 10.1002/jcb.23415 22020763
34. Lysophosphatidylcholine exhibits selective cytotoxicity, accompanied by ROS formation, in RAW 264.7 macrophages. Park CH, Kim MR, Han JM, Jeong TS, Sok DE, Lipids 2009 44 425 435 10.1007/s11745-009-3286-6 19252937
35. Possible protective role for C-reactive protein in atherogenesis. Bhakdi S, Torzewski M, Paprotka K, Schmitt S, Barsoom H, Suriyaphol P, Han S, Lackner KJ, Husmann M, Circulation 2004 109 1870 1876 10.1161/01.CIR.0000124228.08972.26 15037531 (Pubitemid 38509122)
36. C-reactive protein binds to apoptotic cells, protects the cells from assembly of the terminal complement components, and sustains an antiinflammatory innate immune response: implication for symmetric autoimmunity. Gershov D, Kim S, Brot N, Elkon KB, J Exp Med 2000 192 1353 1364 10.1084/jem.192.9.1353 11067883
37. Colocalisation of intraplaque C reactive protein, complement, oxidised low density lipoprotein, and macrophages in stable and unstable angina and acute myocardial infarction. Meuwissen M, van der Wal AC, Niessen HW, Koch KT, de Winter RJ, van der Loos C, Rittersman SZ, Chamuleau SA, Tijssen JG, Becker AE, et al. J Clin Pathol 2006 59 196 201 10.1136/jcp.2005.027235 16443738 (Pubitemid 43235587)
38. C-reactive protein frequently colocalizes with the terminal complement complex in the intima of early atherosclerotic lesions of human coronary arteries. Torzewski J, Torzewski M, Bowyer DE, Frohlich M, Koenig W, Waltenberger J, Fitzsimmons C, Hombach V, Arterioscler Thromb Vasc Biol 1998 18 1386 1392 10.1161/01.ATV.18.9.1386 9743226 (Pubitemid 28421875)