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Volumn 6, Issue , 2013, Pages 183-188

Expression of protein tyrosine kinase 6 (PTK6) in nonsmall cell lung cancer and their clinical and prognostic significance

Author keywords

Nonsmall cell lung cancer; Prognosis; PTK6; Target; Tyrosine kinase

Indexed keywords

MESSENGER RNA; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE 6; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 84875016802     PISSN: 11786930     EISSN: None     Source Type: Journal    
DOI: 10.2147/OTT.S41283     Document Type: Article
Times cited : (22)

References (31)
  • 1
    • 79952224794 scopus 로고    scopus 로고
    • People's Republic of China wrestles with lung cancer
    • Wen C, Dehnel T. People's Republic of China wrestles with lung cancer. Lancet Oncol. 2011;12(1):15.
    • (2011) Lancet Oncol , vol.12 , Issue.1 , pp. 15
    • Wen, C.1    Dehnel, T.2
  • 2
    • 27544479318 scopus 로고    scopus 로고
    • Role of tyrosine kinase inhibitors in cancer therapy
    • Arora A, Scholar EM. Role of tyrosine kinase inhibitors in cancer therapy. J Pharmacol Exp Ther. 2005;315(3):971-979.
    • (2005) J Pharmacol Exp Ther , vol.315 , Issue.3 , pp. 971-979
    • Arora, A.1    Scholar, E.M.2
  • 3
    • 17844390172 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small-cell lung cancer: Current knowledge and future directions
    • Pao W, Miller VA. Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small-cell lung cancer: current knowledge and future directions. J Clin Oncol. 2005;23(11):2556-2568.
    • (2005) J Clin Oncol , vol.23 , Issue.11 , pp. 2556-2568
    • Pao, W.1    Miller, V.A.2
  • 4
    • 1842791537 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic properties of EGFR inhibitors under clinical investigation
    • Thomas SM, Grandis JR. Pharmacokinetic and pharmacodynamic properties of EGFR inhibitors under clinical investigation. Cancer Treat Rev. 2004;30(3):255-268.
    • (2004) Cancer Treat Rev , vol.30 , Issue.3 , pp. 255-268
    • Thomas, S.M.1    Grandis, J.R.2
  • 5
    • 33847246805 scopus 로고    scopus 로고
    • Oncomine 3.0: Genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles
    • Rhodes DR, Kalyana-Sundaram S, Mahavisno V, et al. Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles. Neoplasia. 2007;9(2):166-180.
    • (2007) Neoplasia , vol.9 , Issue.2 , pp. 166-180
    • Rhodes, D.R.1    Kalyana-Sundaram, S.2    Mahavisno, V.3
  • 6
    • 0036718369 scopus 로고    scopus 로고
    • Reactive stroma in human prostate cancer: Induction of myofibroblast phenotype and extracellular matrix remodeling
    • Tuxhorn JA, Ayala GE, Smith MJ, Smith VC, Dang TD, Rowley DR. Reactive stroma in human prostate cancer: induction of myofibroblast phenotype and extracellular matrix remodeling. Clin Cancer Res. 2002;8(9):2912-2923.
    • (2002) Clin Cancer Res , vol.8 , Issue.9 , pp. 2912-2923
    • Tuxhorn, J.A.1    Ayala, G.E.2    Smith, M.J.3    Smith, V.C.4    Dang, T.D.5    Rowley, D.R.6
  • 7
    • 33847701326 scopus 로고    scopus 로고
    • Expression and mutation analysis of the discoidin domain receptors 1 and 2in non-small cell lung carcinoma
    • Ford CE, Lau SK, Zhu CQ, Andersson T, Tsao MS, Vogel WF. Expression and mutation analysis of the discoidin domain receptors 1 and 2in non-small cell lung carcinoma. Br J Cancer. 2007;96(5):808-814.
    • (2007) Br J Cancer , vol.96 , Issue.5 , pp. 808-814
    • Ford, C.E.1    Lau, S.K.2    Zhu, C.Q.3    Andersson, T.4    Tsao, M.S.5    Vogel, W.F.6
  • 8
    • 77954357667 scopus 로고    scopus 로고
    • Discoidin domain receptor 1 is associated with poor prognosis of non-small cell lung carcinomas
    • Yang SH, Baek HA, Lee HJ, et al. Discoidin domain receptor 1 is associated with poor prognosis of non-small cell lung carcinomas. Oncol Rep. 2010;24(2):311-319.
    • (2010) Oncol Rep , vol.24 , Issue.2 , pp. 311-319
    • Yang, S.H.1    Baek, H.A.2    Lee, H.J.3
  • 9
    • 80052341805 scopus 로고    scopus 로고
    • Detection of Brk expression in non-small cell lung cancer: Clinicopathological relevance
    • Fan C, Zhao Y, Liu D, Zhang X, Wang E. Detection of Brk expression in non-small cell lung cancer: clinicopathological relevance. Tumour Biol. 2011;32(5):873-880.
    • (2011) Tumour Biol , vol.32 , Issue.5 , pp. 873-880
    • Fan, C.1    Zhao, Y.2    Liu, D.3    Zhang, X.4    Wang, E.5
  • 10
    • 0028237509 scopus 로고
    • Cloning and characterisation of cDNAs encoding a novel non-receptor tyrosine kinase, brk, expressed in human breast tumours
    • Mitchell PJ, Barker KT, Martindale JE, et al. Cloning and characterisation of cDNAs encoding a novel non-receptor tyrosine kinase, brk, expressed in human breast tumours. Oncogene. 1994;9(8):2383-2390.
    • (1994) Oncogene , vol.9 , Issue.8 , pp. 2383-2390
    • Mitchell, P.J.1    Barker, K.T.2    Martindale, J.E.3
  • 11
    • 0027385426 scopus 로고
    • A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes
    • Lee ST, Strunk KM, Spritz RA. A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes. Oncogene. 1993;8(12):3403-3410.
    • (1993) Oncogene , vol.8 , Issue.12 , pp. 3403-3410
    • Lee, S.T.1    Strunk, K.M.2    Spritz, R.A.3
  • 12
    • 0030827253 scopus 로고    scopus 로고
    • BRK tyrosine kinase expression in a high proportion of human breast carcinomas
    • Barker KT, Jackson LE, Crompton MR. BRK tyrosine kinase expression in a high proportion of human breast carcinomas. Oncogene. 1997;15(7):799-805.
    • (1997) Oncogene , vol.15 , Issue.7 , pp. 799-805
    • Barker, K.T.1    Jackson, L.E.2    Crompton, M.R.3
  • 13
    • 0032789582 scopus 로고    scopus 로고
    • BRK/Sik expression in the gastrointestinal tract and in colon tumors
    • Llor X, Serfas MS, Bie W, et al. BRK/Sik expression in the gastrointestinal tract and in colon tumors. Clin Cancer Res. 1999;5(7):1767-1777.
    • (1999) Clin Cancer Res , vol.5 , Issue.7 , pp. 1767-1777
    • Llor, X.1    Serfas, M.S.2    Bie, W.3
  • 14
    • 1542358939 scopus 로고    scopus 로고
    • The Brk protein tyrosine kinase as a therapeutic target in cancer: Opportunities and challenges
    • Harvey AJ, Crompton MR. The Brk protein tyrosine kinase as a therapeutic target in cancer: opportunities and challenges. Anticancer Drugs. 2004;15(2):107-111.
    • (2004) Anticancer Drugs , vol.15 , Issue.2 , pp. 107-111
    • Harvey, A.J.1    Crompton, M.R.2
  • 15
    • 0042786007 scopus 로고    scopus 로고
    • Use of RNA interference to validate Brk as a novel therapeutic target in breast cancer: Brk promotes breast carcinoma cell proliferation
    • Harvey AJ, Crompton MR. Use of RNA interference to validate Brk as a novel therapeutic target in breast cancer: Brk promotes breast carcinoma cell proliferation. Oncogene. 2003;22(32):5006-5010.
    • (2003) Oncogene , vol.22 , Issue.32 , pp. 5006-5010
    • Harvey, A.J.1    Crompton, M.R.2
  • 16
    • 50549095021 scopus 로고    scopus 로고
    • Brk is coamplified with ErbB2 to promote proliferation in breast cancer
    • Xiang B, Chatti K, Qiu H, et al. Brk is coamplified with ErbB2 to promote proliferation in breast cancer. Proc Natl Acad Sci U S A. 2008;105(34):12463-12468.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.34 , pp. 12463-12468
    • Xiang, B.1    Chatti, K.2    Qiu, H.3
  • 17
    • 0034676337 scopus 로고    scopus 로고
    • Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylation
    • Kamalati T, Jolin HE, Fry MJ, Crompton MR. Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylation. Oncogene. 2000;19(48):5471-5476.
    • (2000) Oncogene , vol.19 , Issue.48 , pp. 5471-5476
    • Kamalati, T.1    Jolin, H.E.2    Fry, M.J.3    Crompton, M.R.4
  • 18
    • 53049087852 scopus 로고    scopus 로고
    • Prognostic value of protein tyrosine kinase 6 (PTK6) for long-term survival of breast cancer patients
    • Aubele M, Walch AK, Ludyga N, et al. Prognostic value of protein tyrosine kinase 6 (PTK6) for long-term survival of breast cancer patients. Br J Cancer. 2008;99(7):1089-1095.
    • (2008) Br J Cancer , vol.99 , Issue.7 , pp. 1089-1095
    • Aubele, M.1    Walch, A.K.2    Ludyga, N.3
  • 19
    • 10044284340 scopus 로고    scopus 로고
    • Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin
    • Chen HY, Shen CH, Tsai YT, Lin FC, Huang YP, Chen RH. Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin. Mol Cell Biol. 2004;24(24):10558-10572.
    • (2004) Mol Cell Biol , vol.24 , Issue.24 , pp. 10558-10572
    • Chen, H.Y.1    Shen, C.H.2    Tsai, Y.T.3    Lin, F.C.4    Huang, Y.P.5    Chen, R.H.6
  • 20
    • 65549108638 scopus 로고    scopus 로고
    • STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation
    • Ikeda O, Miyasaka Y, Sekine Y, et al. STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation. Biochem Biophys Res Commun. 2009;384(1):71-75.
    • (2009) Biochem Biophys Res Commun , vol.384 , Issue.1 , pp. 71-75
    • Ikeda, O.1    Miyasaka, Y.2    Sekine, Y.3
  • 21
    • 24644462342 scopus 로고    scopus 로고
    • Interaction between Brk kinase and insulin receptor substrate-4
    • Qiu H, Zappacosta F, Su W, Annan RS, Miller WT. Interaction between Brk kinase and insulin receptor substrate-4. Oncogene. 2005;24(36):5656-5664.
    • (2005) Oncogene , vol.24 , Issue.36 , pp. 5656-5664
    • Qiu, H.1    Zappacosta, F.2    Su, W.3    Annan, R.S.4    Miller, W.T.5
  • 22
    • 80052584394 scopus 로고    scopus 로고
    • Discovery of novel imidazo[1,2-a]pyrazin-8-amines as Brk/PTK6 inhibitors
    • Zeng H, Belanger DB, Curran PJ, et al. Discovery of novel imidazo[1,2-a]pyrazin-8-amines as Brk/PTK6 inhibitors. Bioorg Med Chem Lett. 2011;21(19):5870-5875.
    • (2011) Bioorg Med Chem Lett , vol.21 , Issue.19 , pp. 5870-5875
    • Zeng, H.1    Belanger, D.B.2    Curran, P.J.3
  • 23
    • 18544365698 scopus 로고    scopus 로고
    • Gene-expression profiles predict survival of patients with lung adenocarcinoma
    • Beer DG, Kardia SL, Huang CC, et al. Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med. 2002;8(8):816-824.
    • (2002) Nat Med , vol.8 , Issue.8 , pp. 816-824
    • Beer, D.G.1    Kardia, S.L.2    Huang, C.C.3
  • 24
    • 0037447191 scopus 로고    scopus 로고
    • Transcriptional gene expression profiling of small cell lung cancer cells
    • Pedersen N, Mortensen S, Sørensen SB, et al. Transcriptional gene expression profiling of small cell lung cancer cells. Cancer Res. 2003;63(8):1943-1953.
    • (2003) Cancer Res , vol.63 , Issue.8 , pp. 1943-1953
    • Pedersen, N.1    Mortensen, S.2    Sørensen, S.B.3
  • 25
    • 0035923583 scopus 로고    scopus 로고
    • Diversity of gene expression in adenocarcinoma of the lung
    • Garber ME, Troyanskaya OG, Schluens K, et al. Diversity of gene expression in adenocarcinoma of the lung. Proc Natl Acad Sci U S A. 2001;98(24):13784-13789.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.24 , pp. 13784-13789
    • Garber, M.E.1    Troyanskaya, O.G.2    Schluens, K.3
  • 26
    • 77956418156 scopus 로고    scopus 로고
    • Gene expression-based classification of non-small cell lung carcinomas and survival prediction
    • Hou J, Aerts J, den Hamer B, et al. Gene expression-based classification of non-small cell lung carcinomas and survival prediction. PLoS One. 2010;5(4):e10312.
    • (2010) PLoS One , vol.5 , Issue.4
    • Hou, J.1    Aerts, J.2    den Hamer, B.3
  • 27
    • 45749140422 scopus 로고    scopus 로고
    • Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival
    • Landi MT, Dracheva T, Rotunno M, et al. Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival. PLoS One. 2008;3(2):e1651.
    • (2008) PLoS One , vol.3 , Issue.2
    • Landi, M.T.1    Dracheva, T.2    Rotunno, M.3
  • 28
    • 28244499333 scopus 로고    scopus 로고
    • Analysis of orthologous gene expression between human pulmonary adenocarcinoma and a carcinogen-induced murine model
    • Stearman RS, Dwyer-Nield L, Zerbe L, et al. Analysis of orthologous gene expression between human pulmonary adenocarcinoma and a carcinogen-induced murine model. Am J Pathol. 2005;167(6):1763-1775.
    • (2005) Am J Pathol , vol.167 , Issue.6 , pp. 1763-1775
    • Stearman, R.S.1    Dwyer-Nield, L.2    Zerbe, L.3
  • 29
    • 34347209095 scopus 로고    scopus 로고
    • Selection of DDX5 as a novel internal control for Q-RT-PCR from microarray data using a block bootstrap re-sampling scheme
    • Su LJ, Chang CW, Wu YC, et al. Selection of DDX5 as a novel internal control for Q-RT-PCR from microarray data using a block bootstrap re-sampling scheme. BMC Genomics. 2007;8:140.
    • (2007) BMC Genomics , vol.8 , pp. 140
    • Su, L.J.1    Chang, C.W.2    Wu, Y.C.3
  • 30
    • 28444448000 scopus 로고    scopus 로고
    • Interactome-transcriptome analysis reveals the high centrality of genes differentially expressed in lung cancer tissues
    • Wachi S, Yoneda K, Wu R. Interactome-transcriptome analysis reveals the high centrality of genes differentially expressed in lung cancer tissues. Bioinformatics. 2005;21(23):4205-4208.
    • (2005) Bioinformatics , vol.21 , Issue.23 , pp. 4205-4208
    • Wachi, S.1    Yoneda, K.2    Wu, R.3
  • 31
    • 10744226708 scopus 로고    scopus 로고
    • A training-testing approach to the molecular classification of resected non-small cell lung cancer
    • Yamagata N, Shyr Y, Yanagisawa K, et al. A training-testing approach to the molecular classification of resected non-small cell lung cancer. Clin Cancer Res. 2003;9(13):4695-4704.
    • (2003) Clin Cancer Res , vol.9 , Issue.13 , pp. 4695-4704
    • Yamagata, N.1    Shyr, Y.2    Yanagisawa, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.