Deciphering of ADP-induced, phosphotyrosine-dependent signaling networks in human platelets by Src-homology 2 region (SH2)-profiling

Proteomics

Volumn 13, Issue 6, 2013, Pages 1016-1027

  Schweigel, Hardy ^a   Geiger, Jörg ^b   Beck, Florian ^c   Buhs, Sophia ^a   Gerull, Helwe ^a   Walter, Ulrich ^d   Sickmann, Albert ^c,e   Nollau, Peter ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c LEIBNIZ INSTITUT FÜR ANALYTISCHE WISSENSCHAFTEN ISAS E V   (Germany)

^d JOHANNES GUTENBERG UNIVERSITY   (Germany)

^e RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Biomedicine; Iloprost; P2Y1 and P2Y12 receptors; Prostacyclin; SH2 domain; Tyrosine phosphorylation

Indexed keywords

ADAPTOR PROTEIN; ADENOSINE DIPHOSPHATE; CELL ADHESION MOLECULE; CYCLIC AMP DEPENDENT PROTEIN KINASE; PHOSPHOTYROSINE; PROTEIN TYROSINE PHOSPHATASE SHP; PURINERGIC P2Y1 RECEPTOR; PURINERGIC P2Y12 RECEPTOR;

ARTICLE; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; INTRACELLULAR SIGNALING; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; THROMBOCYTE; THROMBOCYTE ACTIVATION;

ADENOSINE DIPHOSPHATE; ADENOSINE MONOPHOSPHATE; BLOOD PLATELETS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; HUMANS; ILOPROST; PHOSPHORYLATION; PHOSPHOTYROSINE; PLATELET ACTIVATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PURINERGIC P2Y RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC P2Y1; RECEPTORS, PURINERGIC P2Y12; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; TANDEM MASS SPECTROMETRY;

EID: 84874989675     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201200353     Document Type: Article

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