Effect of clopidogrel administration to healthy volunteers on platelet phosphorylation events triggered by ADP

British Journal of Haematology

Volumn 120, Issue 4, 2003, Pages 633-642

  Contreres, Jean O ^a   Dupuy, Evelyne ^a   Job, Bernard ^b   Habib, Aïda ^a   Bryckaert, Marg̈ke ^a   Rosa, Jean P ^a   Simoneau, Guy ^c   Herbert, Jean M ^b   Savi, Pierre ^b   Levy Toledano, Sylviane ^a,c  

^a INSERM   (France)

^b SANOFI   (France)

^c HÔPITAL LARIBOISIÈRE   (France)

Author keywords

ADP receptors; Clopidogrel; Platelets; Serine threonine phosphorylation; Tyrosine phosphorylation

Indexed keywords

2 METHYLTHIOADENOSINE DIPHOSPHATE TRISODIUM; 3 [[4 [4 (AMINOIMINOMETHYL)PHENYL] 2 THIAZOLYL](1 CARBOXYMETHYL 4 PIPERIDINYL)AMINO]PROPIONIC ACID; ADENOSINE 3' PHOSPHATE 5' PHOSPHATE; ADENOSINE DERIVATIVE; CLOPIDOGREL; CORTACTIN; FIBRINOGEN RECEPTOR; MYOSIN LIGHT CHAIN; PHOSPHOLIPASE C; PLECKSTRIN; PURINE P2Y RECEPTOR; SODIUM DERIVATIVE; THROMBOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; CYTOSKELETON; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; HUMAN; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; THROMBOCYTE AGGREGATION; VOLUNTEER;

ADENOSINE DIPHOSPHATE; ADOLESCENT; ADULT; BENZYLAMINES; BLOOD PLATELETS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; MALE; MEMBRANE PROTEINS; PHOSPHORYLATION; PIPERIDINES; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; RECEPTORS, PURINERGIC P2; SERINE; SIGNAL TRANSDUCTION; THIAZOLES; THIONUCLEOTIDES; THREONINE; TICLOPIDINE; TYROSINE;

EID: 0037327798     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2003.04166.x     Document Type: Article

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