Structural, kinetic and chemical mechanism of isocitrate dehydrogenase-1 from mycobacterium tuberculosis

Biochemistry

Volumn 52, Issue 10, 2013, Pages 1765-1775

  Quartararo, Christine E ^a   Hazra, Saugata ^a   Hadi, Timin ^a   Blanchard, John S ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL INFECTIONS; ISOCITRATE DEHYDROGENASE; KINETIC ISOTOPE EFFECTS; MYCOBACTERIUM TUBERCULOSIS; RATE-LIMITING STEPS; SOLVENT KINETIC ISOTOPE EFFECTS; STRUCTURAL INFORMATION; STRUCTURAL STUDIES;

CARRIER MOBILITY; ESCHERICHIA COLI; ISOTOPES; TUBES (COMPONENTS); X RAY CRYSTALLOGRAPHY;

KINETICS;

2 HYDROXYGLUTARIC ACID; BACTERIAL ENZYME; HOMODIMER; ISOCITRATE DEHYDROGENASE 1; ISOTOPE; MANGANESE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SOLVENT;

ARTICLE; CONTROLLED STUDY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME PURIFICATION; ENZYME STRUCTURE; ENZYME SUBUNIT; GLIOBLASTOMA; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; X RAY CRYSTALLOGRAPHY;

BACTERIAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; HUMANS; HYDROGEN-ION CONCENTRATION; ISOCITRATE DEHYDROGENASE; KINETICS; LIGANDS; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; PROTEIN STRUCTURE, QUATERNARY; STATIC ELECTRICITY; STRUCTURAL HOMOLOGY, PROTEIN;

EID: 84874984795     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi400037w     Document Type: Article

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