CD1d protein structure determines species-selective antigenicity of isoglobotrihexosylceramide (iGb3) to invariant NKT cells

European Journal of Immunology

Volumn 43, Issue 3, 2013, Pages 815-825

  Sanderson, Joseph P ^a   Brennan, Patrick J ^b   Mansour, Salah ^a   Matulis, Gediminas ^c   Patel, Onisha ^d   Lissin, Nikolai ^e   Godfrey, Dale I ^f   Kawahara, Kazuyoshi ^g   Zähringer, Ulrich ^h   Rossjohn, Jamie ^d   Brenner, Michael B ^b   Gadola, Stephan D ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c UNIVERSITY OF BERN   (Switzerland)

^d MONASH UNIVERSITY   (Australia)

^e Immunocore Limited   (United Kingdom)

^f UNIVERSITY OF MELBOURNE   (Australia)

^g KANTO GAKUIN UNIVERSITY   (Japan)

^h RESEARCH CENTER BORSTEL   (Germany)

Author keywords

Antigen presentation; CD1d; INKT; Isogloboside 3; Species differences

Indexed keywords

ANTIGEN; GLYCINE; ISOGLOBOTRIHEXOSYLCERAMIDE; PROTEIN; PROTEIN CD1D; TRYPTOPHAN; UNCLASSIFIED DRUG;

ALPHA HELIX; ANIMAL CELL; ANTIGENICITY; ARTICLE; CONTROLLED STUDY; CYTOLOGY; HUMAN; HUMAN CELL; MOUSE; MUTATION; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; SPECIES DIFFERENCE;

AMINO ACIDS; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, CD1D; GLOBOSIDES; HUMANS; LYMPHOCYTE ACTIVATION; MICE; MODELS, MOLECULAR; NATURAL KILLER T-CELLS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECEPTORS, ANTIGEN, T-CELL; SPECIES SPECIFICITY; TRIHEXOSYLCERAMIDES;

EID: 84874969940     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201242952     Document Type: Article

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