In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype

Neuromuscular Disorders

Volumn 23, Issue 4, 2013, Pages 357-369

  Gineste, C ^a   De Winter, J M ^b   Kohl, C ^c   Witt, C C ^c   Giannesini, B ^a   Brohm, K ^c   Le Fur, Y ^a   Gretz, N ^c   Vilmen, C ^a   Pecchi, E ^a   Jubeau, M ^a   Cozzone, P J ^a   Stienen, G J M ^b,d   Granzier, H ^e   Labeit, S ^c   Ottenheijm, C A C ^b,e   Bendahan, D ^a   Gondin, J ^a  

^a University of Aix Marseille   (France)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d VU UNIVERSITY AMSTERDAM   (Netherlands)

^e UNIVERSITY OF ARIZONA   (United States)

Author keywords

31P MRS; Congenital myopathy; Gene expression; Muscle mechanics; Muscle weakness

Indexed keywords

ADENOSINE TRIPHOSPHATE; MICRORNA; NEBULIN;

ANATOMY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENERGY METABOLISM; GENE EXPRESSION; HETEROZYGOSITY; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; MALE; MICROARRAY ANALYSIS; MOUSE; MUSCLE CONTRACTION; MUSCLE FATIGUE; MUSCLE FUNCTION; MUSCLE STRENGTH; MUSCLE WEAKNESS; NEBULIN GENE; NEMALINE MYOPATHY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEOTIDE SEQUENCE; PHENOTYPE; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA ISOLATION; SKELETAL MUSCLE;

ANIMALS; DISEASE MODELS, ANIMAL; GENE EXPRESSION; HETEROZYGOTE; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; MICE, KNOCKOUT; MUSCLE PROTEINS; MUSCLE STRENGTH; MUSCLE WEAKNESS; MUSCLE, SKELETAL; MUTATION; MYOPATHIES, NEMALINE; PHENOTYPE; SEVERITY OF ILLNESS INDEX;

EID: 84874960353     PISSN: 09608966     EISSN: 18732364     Source Type: Journal    
DOI: 10.1016/j.nmd.2012.12.011     Document Type: Article

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