A sensitive LC-MS/MS method for the simultaneous determination of amoxicillin and ambroxol in human plasma with segmental monitoring

Biomedical Chromatography

Volumn 27, Issue 4, 2013, Pages 520-526

  Dong, Xin ^a   Ding, Li ^a   Cao, Xiaomei ^b   Jiang, Liyuan ^a   Zhong, Shuisheng ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b NANJING GENERAL HOSPITAL OF NANJING MILITARY COMMAND   (China)

Author keywords

Ambroxol; Amoxicillin; HPLC MS MS; Pharmacokinetics; Segmental monitoring

Indexed keywords

PLASMA (HUMAN); WATER INJECTION;

AMBROXOL; AMIDASE; AMOXICILLIN; HPLC-MS-MS; HUMAN PLASMAS; LC-MS-MS; MULTIPLE REACTION MONITORING; PLASMA SAMPLES; SEGMENTAL MONITORING; SIMULTANEOUS DETERMINATIONS;

PHARMACOKINETICS;

ACETIC ACID; AMBROXOL; AMOXICILLIN; BISOPROLOL;

ANALYTIC METHOD; AREA UNDER THE CURVE; ARTICLE; CHINESE; CONTROLLED STUDY; DILUTION; DISTRIBUTION VOLUME; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DEGRADATION; DRUG DETERMINATION; DRUG HALF LIFE; DRUG ISOLATION; DRUG MONITORING; DRUG STABILITY; DRUG STORAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; LIMIT OF QUANTITATION; MAXIMUM PLASMA CONCENTRATION; MEASUREMENT ACCURACY; MULTIPLE REACTION MONITORING; NORMAL HUMAN; ROOM TEMPERATURE; SENSITIVITY AND SPECIFICITY; STORAGE TEMPERATURE; TABLET; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION;

EID: 84874944439     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.2824     Document Type: Article

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