Rapid method for the quantification of amoxicillin and its major metabolites in pig tissues by liquid chromatography-tandem mass spectrometry with emphasis on stability issues

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 861, Issue 1, 2008, Pages 108-116

  Reyns, Tim ^a   Cherlet, Marc ^a   De Baere, Siegrid ^a   De Backer, Patrick ^a   Croubels, Siska ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Amoxicillin; Amoxicillin diketopiperazine 2 ,5 dione; Amoxicilloic acid; Liquid chromatography electrospray ionization tandem mass spectrometry; Pig tissues; Stability

Indexed keywords

AMOXICILLOIC ACID (AMA); POTASSIUM DIHYDROGEN; TANDEM MASS SPECTROMETRY;

ELECTROSPRAY IONIZATION; FORMIC ACID; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; SOLVENTS; TISSUE;

METABOLITES;

ACETONITRILE; AMOXICILLIN; AMOXICILLIN DIKETOPIPERAZINE 2',5' DIONE; AMOXICILLIN PLUS CLAVULANIC ACID; AMOXICILLOIC ACID; BUFFER; DRUG METABOLITE; FORMIC ACID; POTASSIUM DIHYDROGEN PHOSPHATE; SOLVENT; TISSUE EXTRACT; UNCLASSIFIED DRUG; WATER;

ACCURACY; ACIDITY; ADIPOSE TISSUE; ALKALINITY; ANIMAL TISSUE; ARTICLE; DRUG LIVER LEVEL; DRUG MUSCLE LEVEL; DRUG TISSUE LEVEL; EVALUATION; KIDNEY; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MASS SPECTROMETER; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ASSAY; TANDEM MASS SPECTROMETRY; ULTRAFILTRATION;

AMOXICILLIN; ANIMALS; CHROMATOGRAPHY, LIQUID; MOLECULAR STRUCTURE; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SWINE; TANDEM MASS SPECTROMETRY;

SUIDAE;

EID: 37349095607     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.11.007     Document Type: Article

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