Antiangiogenic effects of P-coumaric acid in human endothelial cells

Phytotherapy Research

Volumn 27, Issue 3, 2013, Pages 317-323

  Kong, Chang Seok ^a,b   Jeong, Chul Ho ^c   Choi, Jae Sun ^a,b   Kim, Kil Jung ^a,b   Jeong, Joo Won ^a,b  

^a Kyung Hee University Hospital   (South Korea)

^b Kyung Hee University   (South Korea)

^c Keimyung University   (South Korea)

Author keywords

angiogenesis; antioxidant; cancer prevention; p coumaric acid

Indexed keywords

FIBROBLAST GROWTH FACTOR; HEMOGLOBIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PARA COUMARIC ACID; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; FIBROBLAST GROWTH FACTOR GENE; GENE; GENE EXPRESSION REGULATION; HEMOGLOBIN ANALYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; KIDNEY CARCINOMA; MALE; MOUSE; NONHUMAN; PHARMACOLOGICAL BLOCKING; RAT; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR GENE;

ADENOCARCINOMA; ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS; AORTA; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; COUMARIC ACIDS; DOWN-REGULATION; ENDOTHELIAL CELLS; FIBROBLAST GROWTH FACTOR 2; HUMANS; MALE; MICE; MICE, INBRED BALB C; NEOVASCULARIZATION, PATHOLOGIC; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

RATTUS;

EID: 84874940805     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4718     Document Type: Article

References (29)

1. Antosiewicz J, Ziolkowski W, Kar S, Powolny AA, Singh SV,. 2008. Role of reactive oxygen intermediates in cellular responses to dietary cancer chemopreventive agents. Planta Med 74 (13): 1570-1579.
2. Carmeliet P,. 2005. Angiogenesis in life, disease and medicine. Nature 438 (7070): 932-936. (Pubitemid 43093958)
3. Carmeliet P, Jain RK,. 2000. Angiogenesis in cancer and other diseases. Nature 407 (6801): 249-257.
4. Chiarugi P, Fiaschi T, Taddei ML, et al,. 2001. Two vicinal cysteines confer a peculiar redox regulation to low molecular weight protein tyrosine phosphatase in response to platelet-derived growth factor receptor stimulation. J Biol Chem 276 (36): 33478-33487.
5. Choi YH, Zhang L, Lee WH, Park KY,. 1998. Genistein-induced G2/M arrest is associated with the inhibition of cyclin B1 and the induction of p21 in human breast carcinoma cells. Int J Oncol 13 (2): 391-396. (Pubitemid 28329231)
6. Chung BH, Kim JD, Kim CK, et al,. 2008. Icariin stimulates angiogenesis by activating the MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways in human endothelial cells. Biochem Biophys Res Commun 376 (2): 404-408.
7. Dai J, Peng L, Fan K, et al,. 2009. Osteopontin induces angiogenesis through activation of PI3K/AKT and ERK1/2 in endothelial cells. Oncogene 28 (38): 3412-3422.
8. Ferguson LR, Zhu ST, Harris PJ,. 2005. Antioxidant and antigenotoxic effects of plant cell wall hydroxycinnamic acids in cultured HT-29 cells. Mol Nutr Food Res 49 (6): 585-593. (Pubitemid 40853704)
9. Ferrara N, Davis-Smyth T,. 1997. The biology of vascular endothelial growth factor. Endocr Rev 18 (1): 4-25. (Pubitemid 27076453)
10. Jackson JR, Seed MP, Kircher CH, Willoughby DA, Winkler JD,. 1997. The codependence of angiogenesis and chronic inflammation. FASEB J 11 (6): 457-465. (Pubitemid 27259987)
11. Kerbel R, Folkman J,. 2002. Clinical translation of angiogenesis inhibitors. Nat Rev Cancer 2 (10): 727-739. (Pubitemid 37328908)
12. Kim JH, Park SY, Kim HJ,. 2006. The Effect of Combination Therapy with Radiation and Selective Cyclooxygenase-1 Inhibitor on Xenografted Human Oral Cavity Squamous Cell Carcinoma in Nude Mice. Korean J Otolaryngol 49: 420-425.
13. Lamy S, Lachambre MP, Lord-Dufour S, Beliveau R,. 2010. Propranolol suppresses angiogenesis in vitro: inhibition of proliferation, migration, and differentiation of endothelial cells. Vascul Pharmacol 53 (5-6): 200-208.
14. Luczak K, Balcerczyk A, Soszynski M, Bartosz G,. 2004. Low concentration of oxidant and nitric oxide donors stimulate proliferation of human endothelial cells in vitro. Cell Biol Int 28 (6): 483-486. (Pubitemid 38833656)
15. Markowska AI, Liu FT, Panjwani N,. 2010. Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response. J Exp Med 207 (9): 1981-1993.
16. Matsukawa Y, Marui N, Sakai T, et al,. 1993. Genistein arrests cell cycle progression at G2-M. Cancer Res 53 (6): 1328-1331. (Pubitemid 23097111)
17. Middleton E Jr., Kandaswami C, Theoharides TC,. 2000. The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol Rev 52 (4): 673-751.
18. Milanini J, Vinals F, Pouyssegur J, Pages G,. 1998. p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts. J Biol Chem 273 (29): 18165-18172. (Pubitemid 28334735)
19. Park HJ, Kim SR, Bae SK, et al,. 2009. Neuromedin B induces angiogenesis via activation of ERK and Akt in endothelial cells. Exp Cell Res 315 (19): 3359-3369.
20. Rhee SG, Bae YS, Lee SR, Kwon J,. 2000. Hydrogen peroxide: a key messenger that modulates protein phosphorylation through cysteine oxidation. Sci STKE 2000 (53): pe1.
21. Romero I, Paez A, Ferruelo A, Lujan M, Berenguer A,. 2002. Polyphenols in red wine inhibit the proliferation and induce apoptosis of LNCaP cells. BJU Int 89 (9): 950-954. (Pubitemid 34535434)
22. Seo YK, Kim SJ, Boo YC, Baek JH, Lee SH, Koh JS,. 2010. Effects of p-coumaric acid on erythema and pigmentation of human skin exposed to ultraviolet radiation. Clin Exp Dermatol 36 (3): 260-266.
23. Shono T, Ono M, Izumi H, et al,. 1996. Involvement of the transcription factor NF-kappaB in tubular morphogenesis of human microvascular endothelial cells by oxidative stress. Mol Cell Biol 16 (8): 4231-4239. (Pubitemid 26251224)
24. Ushio-Fukai M, Alexander RW,. 2004. Reactive oxygen species as mediators of angiogenesis signaling: role of NAD(P)H oxidase. Mol Cell Biochem 264 (1-2): 85-97. (Pubitemid 39366107)
25. Vepa S, Scribner WM, Parinandi NL, English D, Garcia JG, Natarajan V,. 1999. Hydrogen peroxide stimulates tyrosine phosphorylation of focal adhesion kinase in vascular endothelial cells. Am J Physiol 277 (1 Pt 1): L150-158. (Pubitemid 29356762)
26. Wang YD, Hu Y, Zhang L, Sun CY,. 2008. Brain derived neurotrophic factor induces endothelial cells angiogenesis through AKT and ERK1/2 signal pathway. Zhongguo Shi Yan Xue Ye Xue Za Zhi 16 (1): 175-180.
27. Yasuda M, Ohzeki Y, Shimizu S, et al,. 1999. Stimulation of in vitro angiogenesis by hydrogen peroxide and the relation with ETS-1 in endothelial cells. Life Sci 64 (4): 249-258. (Pubitemid 29049308)
28. Yi EY, Park SY, Song HS, et al,. 2006. KR-31831, a new synthetic anti-ischemic agent, inhibits in vivo and in vitro angiogenesis. Exp Mol Med 38 (5): 502-508.
29. Zang LY, Cosma G, Gardner H, Shi X, Castranova V, Vallyathan V,. 2000. Effect of antioxidant protection by p-coumaric acid on low-density lipoprotein cholesterol oxidation. Am J Physiol Cell Physiol 279 (4): C954-960.