The anti-diabetic drug glibenclamide is an agonist of the transient receptor potential Ankyrin 1 (TRPA1) ion channel

European Journal of Pharmacology

Volumn 704, Issue 1-3, 2013, Pages 15-22

  Babes, Alexandru ^a,b   Fischer, Michael J M ^a   Filipovic, Milos ^a   Engel, Matthias A ^a   Flonta, Maria Luiza ^b   Reeh, Peter W ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF BUCHAREST   (Romania)

Author keywords

Diabetes; Dorsal root ganglion; Pain; Sulphonylurea; TRP channel

Indexed keywords

ALLYL ISOTHIOCYANATE; CALCIUM; GLIBENCLAMIDE; N (4 ISOPROPYLPHENYL) 2 (1,2,3,6 TETRAHYDRO 1,3 DIMETHYL 2,6 DIOXO 7H PURIN 7 YL)ACETAMIDE; PROTEIN INHIBITOR; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1 AGONIST; TRANSIENT RECEPTOR POTENTIAL CHANNEL AFFECTING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM TRANSPORT; CELL ACTIVATION; CELL FUNCTION; CELL SUBPOPULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG SENSITIVITY; EVOKED RESPONSE; GENETIC TRANSFECTION; HUMAN; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; SENSORY NERVE CELL;

ACETANILIDES; ANIMALS; CALCIUM; CALCIUM CHANNELS; CELLS, CULTURED; CYSTEINE; DIAZOXIDE; GANGLIA, SPINAL; GLYBURIDE; HEK293 CELLS; HUMANS; HYPOGLYCEMIC AGENTS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; PURINES; RECOMBINANT PROTEINS; SENSORY RECEPTOR CELLS; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

EID: 84874936255     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.02.018     Document Type: Article

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