Characterization of selective Calcium-Release Activated Calcium channel blockers in mast cells and T-cells from human, rat, mouse and guinea-pig preparations

European Journal of Pharmacology

Volumn 704, Issue 1-3, 2013, Pages 49-57

  Rice, Louise V ^a   Bax, Heather J ^a   Russell, Linda J ^a   Barrett, Victoria J ^a   Walton, Sarah E ^a   Deakin, Angela M ^a   Thomson, Sally A ^a   Lucas, Fiona ^a   Solari, Roberto ^a   House, David ^a   Begg, Malcolm ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

GSK 5498A; GSK 7975A; ICRAC; Mast cell; Orai1; T cell

Indexed keywords

2,6 DIFLUORO N [1 [2 FLUORO 6 (TRIFLUOROMETHYL)BENZYL] 1H PYRAZOL 3 YL]BENZAMIDE; 2,6 DIFLUORO N [1 [4 HYDROXY 2 (TRIFLUOROMETHYL)BENZYL] 1H PYRAZOL 3 YL]BENZAMIDE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL; CYTOKINE; GSK 5498A; GSK 7975A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL ACTIVATION; CELL FUNCTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG INHIBITION; DRUG MECHANISM; DRUG SYNTHESIS; EMBRYO; FEMALE; GUINEA PIG; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCOMPETENT CELL; IN VITRO STUDY; MALE; MAST CELL; MEDIATOR RELEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; T LYMPHOCYTE;

ANIMALS; BENZAMIDES; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CELL LINE; CELLS, CULTURED; CYTOKINES; FEMALE; GUINEA PIGS; HUMANS; LEUKOCYTES, MONONUCLEAR; LUNG; MALE; MAST CELLS; MICE; MICE, INBRED BALB C; OVALBUMIN; PYRAZOLES; RATS; SPLEEN; T-LYMPHOCYTES; TRACHEA;

EID: 84874934753     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.02.022     Document Type: Article

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