The action of selective CRAC channel blockers is affected by the Orai pore geometry

Cell Calcium

Volumn 53, Issue 2, 2013, Pages 139-151

  Derler, Isabella ^a   Schindl, Rainer ^a   Fritsch, Reinhard ^a   Heftberger, Peter ^a   Riedl, Maria Christine ^a   Begg, Malcolm ^b   House, David ^b   Romanin, Christoph ^a  

^a JOHANNES KEPLER UNIVERSITY LINZ   (Austria)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Calcium release activated calcium (CRAC) channel; GSK 7975A; Orai1; Orai3; Stromal interaction molecule 1 (STIM1)

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 2; GSK 5503A; GSK 7975A; STROMAL INTERACTION MOLECULE 1; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CALCIUM TRANSPORT; DRUG MECHANISM; DRUG STRUCTURE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; IC 50; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 84873522561     PISSN: 01434160     EISSN: 15321991     Source Type: Journal    
DOI: 10.1016/j.ceca.2012.11.005     Document Type: Article

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