Isolation of Rare Tumor Cells from Blood Cells with Buoyant Immuno-Microbubbles

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Shi, Guixin ^a   Cui, Wenjin ^b   Benchimol, Michael ^c   Liu, Yu Tsueng ^a   Mattrey, Robert F ^a,b   Mukthavaram, Rajesh ^a   Kesari, Santosh ^a,d   Esener, Sadik C ^a,e   Simberg, Dmitri ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITHELIAL CELL ADHESION MOLECULE; FLUOROCARBON;

ANIMAL CELL; ARTICLE; BLOOD CELL; BUOYANT IMMUNO MICROBUBBLE; CANCER CELL CULTURE; CELL ADHESION; CELL ANALYSIS; CELL BINDING; CELL ENUMERATION; CELL FRACTIONATION; CELL ISOLATION; CELL SEPARATION; CELLULAR PARAMETERS; CIRCULATING TUMOR CELL; CONTROLLED STUDY; EMULSION; FEASIBILITY STUDY; FLOTATION; HUMAN; HUMAN CELL; IMMUNOMAGNETIC SEPARATION; MALE; METASTASIS; MICROBUBBLE; MOUSE; NONHUMAN; RARE TUMOR CELL;

ANTIBODIES, MONOCLONAL; ANTIGENS, NEOPLASM; BLOOD CELLS; CELL ADHESION MOLECULES; CELL LINE, TUMOR; HUMANS; IMMUNOMAGNETIC SEPARATION; MICROBUBBLES; MODELS, THEORETICAL; NEOPLASTIC CELLS, CIRCULATING; PROTEIN BINDING;

EID: 84874887322     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058017     Document Type: Article

References (39)

1. Fehm T, Sagalowsky A, Clifford E, Beitsch P, Saboorian H, et al. (2002) Cytogenetic evidence that circulating epithelial cells in patients with carcinoma are malignant. Clin Cancer Res 8: 2073-2084.
2. Steeg PS, (2006) Tumor metastasis: mechanistic insights and clinical challenges. Nat Med 12: 895-904.
3. Pantel K, Brakenhoff RH, (2004) Dissecting the metastatic cascade. Nat Rev Cancer 4: 448-456.
4. Hager G, Cacsire-Castillo Tong D, Schiebel I, Rezniczek GA, Watrowski R, et al. (2005) The use of a panel of monoclonal antibodies to enrich circulating breast cancer cells facilitates their detection. Gynecol Oncol 98: 211-216.
5. Krag DN, Ashikaga T, Moss TJ, Kusminsky RE, Feldman S, et al. (1999) Breast Cancer Cells in the Blood: A Pilot Study. Breast J 5: 354-358.
6. Marth C, Kisic J, Kaern J, Trope C, Fodstad O, (2002) Circulating tumor cells in the peripheral blood and bone marrow of patients with ovarian carcinoma do not predict prognosis. Cancer 94: 707-712.
7. Molnar B, Ladanyi A, Tanko L, Sreter L, Tulassay Z, (2001) Circulating tumor cell clusters in the peripheral blood of colorectal cancer patients. Clin Cancer Res 7: 4080-4085.
8. Tveito S, Maelandsmo GM, Hoifodt HK, Rasmussen H, Fodstad O, (2007) Specific isolation of disseminated cancer cells: a new method permitting sensitive detection of target molecules of diagnostic and therapeutic value. Clin Exp Metastasis 24: 317-327.
9. Rao CG, Chianese D, Doyle GV, Miller MC, Russell T, et al. (2005) Expression of epithelial cell adhesion molecule in carcinoma cells present in blood and primary and metastatic tumors. Int J Oncol 27: 49-57.
10. Cristofanilli M, Budd GT, Ellis MJ, Stopeck A, Matera J, et al. (2004) Circulating tumor cells, disease progression, and survival in metastatic breast cancer. N Engl J Med 351: 781-791.
11. Riethdorf S, Fritsche H, Muller V, Rau T, Schindlbeck C, et al. (2007) Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the CellSearch system. Clin Cancer Res 13: 920-928.
12. Kraeft SK, Ladanyi A, Galiger K, Herlitz A, Sher AC, et al. (2004) Reliable and sensitive identification of occult tumor cells using the improved rare event imaging system. Clin Cancer Res 10: 3020-3028.
13. Bauer KD, de la Torre-Bueno J, Diel IJ, Hawes D, Decker WJ, et al. (2000) Reliable and sensitive analysis of occult bone marrow metastases using automated cellular imaging. Clin Cancer Res 6: 3552-3559.
14. Krivacic RT, Ladanyi A, Curry DN, Hsieh HB, Kuhn P, et al. (2004) A rare-cell detector for cancer. Proc Natl Acad Sci U S A 101: 10501-10504.
15. Nagrath S, Sequist LV, Maheswaran S, Bell DW, Irimia D, et al. (2007) Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature 450: 1235-1239.
16. Khoja L, Backen A, Sloane R, Menasce L, Ryder D, et al. (2011) A pilot study to explore circulating tumour cells in pancreatic cancer as a novel biomarker. Br J Cancer.
17. Adams AA, Okagbare PI, Feng J, Hupert ML, Patterson D, et al. (2008) Highly efficient circulating tumor cell isolation from whole blood and label-free enumeration using polymer-based microfluidics with an integrated conductivity sensor. Journal of the American Chemical Society 130: 8633-8641.
18. Xu T, Lu B, Tai YC, Goldkorn A, (2010) A Cancer Detection Platform Which Measures Telomerase Activity from Live Circulating Tumor Cells Captured on a Microfilter. Cancer Research 70: 6420-6426.
19. Schutt EG, Klein DH, Mattrey RM, Riess JG, (2003) Injectable microbubbles as contrast agents for diagnostic ultrasound imaging: the key role of perfluorochemicals. Angew Chem Int Ed Engl 42: 3218-3235.
20. Von Bibra H, Voigt JU, Froman M, Bone D, Wranne B, et al. (1999) Interaction of Microbubbles with Ultrasound. Echocardiography 16: 733-741.
21. Simberg D, Mattrey R, (2009) Targeting of perfluorocarbon microbubbles to selective populations of circulating blood cells. J Drug Target 17: 392-398.
22. Sedlak J, Lindsay RH, (1968) Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Anal Biochem 25: 192-205.
23. Karmali PP, Chao Y, Park JH, Sailor MJ, Ruoslahti E, et al. (2012) Different effect of hydrogelation on antifouling and circulation properties of dextran-iron oxide nanoparticles. Mol Pharm 9: 539-545.
24. Bouvet M, Yang M, Nardin S, Wang X, Jiang P, et al. (2000) Chronologically-specific metastatic targeting of human pancreatic tumors in orthotopic models. Clin Exp Metastasis 18: 213-218.
25. Sugahara KN, Teesalu T, Karmali PP, Kotamraju VR, Agemy L, et al. (2009) Tissue-penetrating delivery of compounds and nanoparticles into tumors. Cancer Cell 16: 510-520.
26. Grover WH, Bryan AK, Diez-Silva M, Suresh S, Higgins JM, et al. (2011) Measuring single-cell density. Proceedings of the National Academy of Sciences of the United States of America 108: 10992-10996.
27. Myrset AH, Fjerdingstad HB, Bendiksen R, Arbo BE, Bjerke RM, et al. (2011) Design and Characterization of Targeted Ultrasound Microbubbles for Diagnostic Use. Ultrasound in Medicine and Biology 37: 136-150.
28. Lee AP, Hettiarachchi K, Talu E, Longo ML, Dayton PA, (2007) On-chip generation of microbubbles as a practical technology for manufacturing contrast agents for ultrasonic imaging. Lab on a Chip 7: 463-468.
29. Sboros V, Glynos E, Pye SD, Moran CM, Butler M, et al. (2007) Nanomechanical probing of microbubbles using the atomic force microscope. Ultrasonics 46: 349-354.
30. Wong JY, Kuhl TL, Israelachvili JN, Mullah N, Zalipsky S, (1997) Direct measurement of a tethered ligand-receptor interaction potential. Science 275: 820-822.
31. Cevc G, Marsh D (1987) Phospholipid Bilayers. Physical Principles and Models.New york:. Wiley.
32. Podell S, Burrascano C, Gaal M, Golec B, Maniquis J, et al. (1999) Physical and biochemical stability of Optison (R), an injectable ultrasound contrast agent. Biotechnology and Applied Biochemistry 30: 213-223.
33. Yu M, Stott S, Toner M, Maheswaran S, Haber DA, (2011) Circulating tumor cells: approaches to isolation and characterization. J Cell Biol 192: 373-382.
34. Allard WJ, Matera J, Miller MC, Repollet M, Connelly MC, et al. (2004) Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases. Clinical Cancer Research 10: 6897-6904.
35. Pecot CV, Bischoff FZ, Mayer JA, Wong KL, Pham T, et al. (2011) A novel platform for detection of CK+ and CK- CTCs. Cancer Discov 1: 580-586.
36. Huang J, Qi R, Quackenbush J, Dauway E, Lazaridis E, et al. (2001) Effects of ischemia on gene expression. J Surg Res 99: 222-227.
37. Smirnov DA, Zweitzig DR, Foulk BW, Miller MC, Doyle GV, et al. (2005) Global gene expression profiling of circulating tumor cells. Cancer Res 65: 4993-4997.
38. Sieuwerts AM, Kraan J, Bolt-de Vries J, van der Spoel P, Mostert B, et al. (2009) Molecular characterization of circulating tumor cells in large quantities of contaminating leukocytes by a multiplex real-time PCR. Breast Cancer Res Treat 118: 455-468.
39. Ferrara K, Pollard R, Borden M, (2007) Ultrasound microbubble contrast agents: fundamentals and application to gene and drug delivery. Annu Rev Biomed Eng 9: 415-447.