A cancer detection platform which measures telomerase activity from live circulating tumor cells captured on a microfilter

Cancer Research

Volumn 70, Issue 16, 2010, Pages 6420-6426

  Xu, Tong ^a   Lu, Bo ^b   Tai, Yu Chong ^b   Goldkorn, Amir ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b California Institute of Technology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TELOMERASE; TUMOR MARKER; PARYLENE; POLYMER; XYLENE;

ARTICLE; CANCER DIAGNOSIS; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; FILTER; HUMAN; HUMAN CELL; MICROFILTER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCANNING ELECTRON MICROSCOPY; TUMOR CELL; BLOOD; CASE CONTROL STUDY; CELL SEPARATION; CHEMISTRY; DEVICES; ENZYMOLOGY; MALE; METABOLISM; MICROFLUIDIC ANALYSIS; PATHOLOGY; PROCEDURES; PROSTATE TUMOR; TUMOR CELL LINE; TUMOR EMBOLISM;

CASE-CONTROL STUDIES; CELL LINE, TUMOR; CELL SEPARATION; HUMANS; MALE; MICROFLUIDIC ANALYTICAL TECHNIQUES; NEOPLASTIC CELLS, CIRCULATING; POLYMERS; PROSTATIC NEOPLASMS; TELOMERASE; XYLENES;

EID: 77955744007     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-0686     Document Type: Article

References (20)

1. Cohen SJ, Punt CJ, Iannotti N, et al. Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer. J Clin Oncol 2008;26:3213-21.
2. de Bono JS, Scher HI, Montgomery RB, et al. Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer. Clin Cancer Res 2008;14:6302-9.
3. Gasent Blesa JM, Alberola Candel V, Esteban Gonzalez E, et al. Circulating tumor cells in breast cancer: methodology and clinical repercussions. Clin Transl Oncol 2008;10:399-406.
4. Goodman OB, Jr., Fink LM, Symanowski JT, et al. Circulating tumor cells in patients with castration-resistant prostate cancer baseline values and correlation with prognostic factors. Cancer Epidemiol Biomarkers Prev 2009;18:1904-13.
5. Ignatiadis M, Xenidis N, Perraki M, et al. Different prognostic value of cytokeratin-19 mRNA positive circulating tumor cells according to estrogen receptor and HER2 status in early-stage breast cancer. J Clin Oncol 2007;25:5194-202.
6. Shaffer DR, Leversha MA, Danila DC, et al. Circulating tumor cell analysis in patients with progressive castration-resistant prostate cancer. Clin Cancer Res 2007;13:2023-9.
7. Cristofanilli M, Budd GT, Ellis MJ, et al. Circulating tumor cells, disease progression, and survival in metastatic breast cancer. N Engl J Med 2004;351:781-91. (Pubitemid 39095313)
8. Nagrath S, Sequist LV, Maheswaran S, et al. Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature 2007;450:1235-9.
9. Zheng S, Lin H, Liu JQ, et al. Membrane microfilter device for selective capture, electrolysis and genomic analysis of human circulating tumor cells. J Chromatogr A 2007;1162:154-61. (Pubitemid 47187403)
10. Bravaccini S, Sanchini MA, Amadori A, et al. Potential of telomerase expression and activity in cervical specimens as a diagnostic tool. J Clin Pathol 2005;58:911-4. (Pubitemid 41265273)
11. Hiyama E, Saeki T, Hiyama K, et al. Telomerase activity as a marker of breast carcinoma in fine-needle aspirated samples. Cancer 2000;90:235-8. (Pubitemid 30660111)
12. Marchetti A, Bertacca G, Buttitta F, et al. Telomerase activity as a prognostic indicator in stage I non-small cell lung cancer. Clin Cancer Res 1999;5:2077-81. (Pubitemid 29399261)
13. Meeker AK. Telomeres and telomerase in prostatic intraepithelial neoplasia and prostate cancer biology. Urol Oncol 2006;24:122-30.
14. Poremba C, Willenbring H, Hero B, et al. Telomerase activity distinguishes between neuroblastomas with good and poor prognosis. Ann Oncol 1999;10:715-21. (Pubitemid 29342378)
15. Shay JW, Bacchetti S. A survey of telomerase activity in human cancer. Eur J Cancer 1997;33:787-91. (Pubitemid 27239490)
16. Streutker CJ, Thorner P, Fabricius N, Weitzman S, Zielenska M. Telomerase activity as a prognostic factor in neuroblastomas. Pediatr Dev Pathol 2001;4:62-7. (Pubitemid 32155690)
17. Wright WE, Piatyszek MA, Rainey WE, Byrd W, Shay JW. Telomerase activity in human germline and embryonic tissues and cells. Dev Genet 1996;18:173-9. (Pubitemid 26116862)
18. Xu T, Xu Y, Liao CP, Lau R, Goldkorn A. Reprogramming murine telomerase rapidly inhibits the growth of mouse cancer cells in vitro and in vivo. Mol Cancer Ther 2010;9:438-49.
19. Went PT, Lugli A, Meier S, et al. Frequent EpCam protein expression in human carcinomas. Hum Pathol 2004;35:122-8. (Pubitemid 38133932)
20. Polyak K, Weinberg RA. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 2009;9:265-73.