The effects of platelet gel-released supernatant on human fibroblasts

Wound Repair and Regeneration

Volumn 21, Issue 2, 2013, Pages 300-308

  Giusti, Ilaria ^a   Rughetti, Anna ^b   D'Ascenzo, Sandra ^a   Di Stefano, Gabriella ^a   Nanni, Maria Rita ^a   Millimaggi, Danilo ^a   Dell'Orso, Luigi ^b   Dolo, Vincenza ^a  

^a UNIVERSITY OF L'AQUILA   (Italy)

^b SAN SALVATORE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GROWTH FACTOR;

ARTICLE; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CONTROLLED STUDY; FIBROBLAST; GEL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SUPERNATANT; THROMBOCYTE; WOUND HEALING;

BLOOD PLATELETS; BLOTTING, WESTERN; CARRIER PROTEINS; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; FIBROBLASTS; GELS; HUMANS; LIPOPROTEINS; MATRIX METALLOPROTEINASES; REGENERATION; TRANS-ACTIVATORS; WOUND HEALING; WOUNDS AND INJURIES;

EID: 84874873848     PISSN: 10671927     EISSN: 1524475X     Source Type: Journal    
DOI: 10.1111/wrr.12025     Document Type: Article

References (36)

1. Jurk K, Kehrel BE,. Platelets: physiology and biochemistry. Semin Thromb Hemost 2005; 31: 381-392.
2. Diegelmann RF, Evans MC,. Wound healing: an overview of acute, fibrotic and delayed healing. Front Biosci 2004; 9: 283-289.
3. Borzini P, Mazzucco L,. Platelet rich plasma (PRP) and platelet derivatives for topical therapy. What is true from the biological view point? Vox Sang 2007; 2: 272-281.
4. Bava ED, Barber FA,. Platelet-rich plasma products in sports medicine. Phys Sportsmed 2011; 39: 94-99.
5. Franchini M, Rocca G, Bosinelli A, Governa M, Olzer D, Fiorini S, Aloisi O, Scalvi A, Gandini G, Barisoni D, Marcer M, Aprili G,. Use of platelet gel and bone from tissue bank in reconstructive orthopaedic surgery: the regenerative medicine as a multidisciplinary model. Blood Transfus 2006; 4: 296-310.
6. Rozman P, Bolta Z,. Use of platelet growth factors in treating wounds and soft-tissue injuries. Acta Dermatovenerol Alp Panonica Adriat 2007; 16: 156-165.
7. Okuda K, Kawase T, Momose M, Murata M, Saito Y, Suzuki H, Wolff LF, Yoshie H,. Platelet-rich plasma contains high levels of platelet-derived growth factor and transforming growth factor-beta and modulates the proliferation of periodontally related cells in vitro. J Periodontol 2003; 74: 849-857.
8. Mazzucco L, Cattana E, Orecchia S, Borzini P,. Enhancing of fibroblast proliferation by platelet extract. Vox Sang 2004; 87 (Suppl. S2-S16): 13.
9. Grazul-Bilska AT, Johnson ML, Bilski JJ, Redmer DA, Reynolds LP, Abdullah A, Abdullah KM,. Wound healing: the role of growth factors. Drugs Today (Barc) 2003; 39: 787-800.
10. Pintucci G, Froum S, Pinnell J, Mignatti P, Rafii S, Green D,. Trophic effects of platelets on cultured endothelial cells are mediated by platelet-associated fibroblast growth factor-2 (FGF-2) and vascular endothelial growth factor (VEGF). Thromb Haemost 2002; 88: 834-842.
11. Rosenthal AR, Harbury C, Egbert PR, Rubenstein E,. Use of a platelet-fibrinogen-thrombin mixture as a corneal adhesive: experiments with sutureless lamellar keratoplasty in the rabbit. J Biol Chem 1975; 14: 872-875.
12. Knighton DR, Ciresi KF, Fiegel VD, Austin LL, Butler EL,. Classification and treatment of chronic nonhealing wounds. Successful treatment with autologous platelet-derived wound healing factors (PDWHF). Ann Surg 1986; 204: 322-330.
13. Lynch SE, Nixon JC, Colvin RB, Antoniades HN,. Role of platelet-derived growth factor in wound healing: synergistic effects with other growth factors. Proc Natl Acad Sci U S A 1987; 84: 7696-7700.
14. Lynch SE, Williams RC, Polson AM, Howell TH, Reddy MS, Zappa UE, Antoniades HN,. A combination of platelet-derived and insulin-like growth factors enhances periodontal regeneration. J Clin Periodontol 1989; 16: 545-548.
15. Borzini P, Mazzucco I, Giampaolo A, Hassen HJ,. Platelet gel-the Italian way: a call for procedure standardization and quality control. Transfus Med 2006; 16: 303-304.
16. Kim DH, Je YJ, Kim CD, Lee YH, Seo YJ, Lee JH, Lee Y,. Can platelet-rich plasma be used for skin rejuvenation? Evaluation of effects of platelet-rich plasma on human dermal fibroblast. Ann Dermatol 2011; 23: 424-431.
17. Giusti I, Rughetti A, D'Ascenzo S, Millimaggi D, Pavan A, Dell'Orso L, Dolo V,. Identification of an optimal concentration of platelet gel for promoting angiogenesis in human endothelial cells. Transfusion 2009; 49: 771-778.
18. Taraboletti G, Roberts D, Liotta LA, Giavazzi R,. Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: a potential angiogenesis regulatory factor. J Cell Biol 1990; 111: 765-772.
19. Nwomeh BC, Yager DR, Cohen IK,. Physiology of the chronic wound. Clin Plast Surg 1998; 25: 341-356.
20. Liu Y, Kalén A, Risto O, Wahlström O,. Fibroblast proliferation due to exposure to a platelet concentrate in vitro is pH dependent. Wound Repair Regen 2002; 10: 336-340.
21. Schultz GS, Davidson JM, Kirsner RS, Bornstein P, Herman IM,. Dynamic reciprocity in the wound microenvironment. Wound Repair Regen 2011; 19: 134-148.
22. Bennett NT, Schultz GS,. Growth factors and wound healing: biochemical properties of growth factors and their receptors. Am J Surg 1993; 165: 728-737.
23. Borzini P, Mazzucco L,. Platelet gels and releasates. Curr Opin Hematol 2005; 12: 473-479.
24. Hetzel M, Bachem M, Anders D, Trischler G, Faehling M,. Different effects of growth factors on proliferation and matrix production of normal and fibrotic human lung fibroblasts. Lung 2005; 183: 225-237.
25. Clark RA,. Regulation of fibroplasia in cutaneous wound repair. Am J Med Sci 1993; 306: 42-48.
26. Servold SA,. Growth factors in wound healing. Clin Podiatr Med Surg 1991; 8: 937-953.
27. Presta M, Dell'Era P, Mitola S, Moroni E, Ronca R, Rusnati M,. Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis. Cytokine Growth Factor Rev 2005; 16: 159-178.
28. Mazzucco L, Medici D, Serra M, Panizza R, Rivara G, Orecchia S, Libener R, Cattana E, Levis A, Betta PG, Borzini P,. The use of autologous platelet gel to treat difficult-to-heal wounds: a pilot study. Transfusion 2004; 44: 1013-1018.
29. Anitua E, Andia I, Ardanza B, Nurden P, Nurden AT,. Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 2004; 91: 4-15.
30. Sánchez AR, Sheridan PJ, Kupp LI,. Is platelet-rich plasma the perfect enhancement factor? A current review. Int J Oral Maxillofac Implants 2003; 18: 93-103.
31. Graziani F, Ivanovski S, Cei S, Ducci F, Tonetti M, Gabriele M,. The in vitro effect of different PRP concentrations on osteoblasts and fibroblasts. Clin Oral Implants Res 2006; 17: 212-219.
32. Krasna M, Domanovic̈ D, Tomsic A, Svajger U, Jeras M,. Platelet gel stimulates proliferation of human dermal fibroblasts in vitro. Acta Dermatovenerol Alp Panonica Adriat 2007; 16: 105-110.
33. Creeper F, Ivanovski S,. Effect of autologous and allogenic platelet-rich plasma on human gingival fibroblast function. Oral Dis 2012; 18: 494-500.
34. Cho JW, Kim SA, Lee KS,. Platelet-rich plasma induces increased expression of G1 cell cycle regulators, type I collagen, and matrix metalloproteinase-1 in human skin fibroblasts. Int J Mol Med 2012; 29: 32-36.
35. Rughetti A, Giusti I, D'Ascenzo S, Leocata P, Carta G, Pavan A, Dell'Orso L, Dolo V,. Platelet gel-released supernatant modulates the angiogenic capability of human endothelial cells. Blood Transfus 2008; 6: 12-17.
36. Liu Y, Min D, Bolton T, Nubé V, Twigg SM, Yue DK, McLennan SV,. Increased matrix metalloproteinase-9 predicts poor wound healing in diabetic foot ulcers. Diabetes Care 2009; 32: 117-119.