Insect Odorant Response Sensitivity Is Tuned by Metabotropically Autoregulated Olfactory Receptors

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Getahun, Merid N ^a   Olsson, Shannon B ^a   Lavista Llanos, Sofia ^a   Hansson, Bill S ^a   Wicher, Dieter ^a  

^a MAX PLANCK INSTITUTE FOR CHEMICAL ECOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; IONOTROPIC RECEPTOR; LIGAND GATED ION CHANNEL; ODORANT SPECIFIC PROTEIN; RECEPTOR; UBIQUITOS CORECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; AUTOREGULATION; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; GENETIC MANIPULATION; INTRACELLULAR SIGNALING; NERVE CELL; NONHUMAN; OLFACTORY DISCRIMINATION; OLFACTORY RECEPTOR; PERCEPTIVE THRESHOLD; RECEPTOR DOWN REGULATION; SENSORY STIMULATION; STIMULUS RESPONSE; TASTE BUD;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CYCLIC AMP; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; HOMEOSTASIS; INSECTS; ODORS; OLFACTORY RECEPTOR NEURONS; RECEPTORS, IONOTROPIC GLUTAMATE; RECEPTORS, ODORANT; SENSORY THRESHOLDS; SIGNAL TRANSDUCTION; STIMULATION, CHEMICAL;

EID: 84874856578     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058889     Document Type: Article

References (41)

1. Dethier VG (1947) Chemical Insect Attractants and Repellents.: Blakiston, Philadelphia.
2. Hansson BS, Stensmyr MC, (2011) Evolution of insect olfaction. Neuron 72: 698-711.
3. Kaissling KE (2009) The sensitivity of the insect nose: The example of Bombyx mori. In: Gutiérrez A, Marco S, editors. Biologically Inspired Signal Processing for Chemical Sensing: Springer-Verlag, Berlin. 170.
4. Clyne PJ, Warr CG, Freeman MR, Lessing D, Kim J, et al. (1999) A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila. Neuron 22: 327-338.
5. Vosshall LB, Amrein H, Morozov PS, Rzhetsky A, Axel R, (1999) A spatial map of olfactory receptor expression in the Drosophila antenna. Cell 96: 725-736.
6. Benton R, Vannice KS, Gomez-Diaz C, Vosshall LB, (2009) Variant ionotropic glutamate receptors as chemosensory receptors in Drosophila. Cell 136: 149-162.
7. Benton R, Sachse S, Michnick SW, Vosshall LB, (2006) Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo. PLoS Biol 4: e20.
8. Sato K, Pellegrino M, Nakagawa T, Nakagawa T, Vosshall LB, et al. (2008) Insect olfactory receptors are heteromeric ligand-gated ion channels. Nature 452: 1002-1006.
9. Wicher D, Schäfer R, Bauernfeind R, Stensmyr MC, Heller R, et al. (2008) Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels. Nature 452: 1007-1011.
10. Robertson HM, Warr CG, Carlson JR, (2003) Molecular evolution of the insect chemoreceptor gene superfamily in Drosophila melanogaster. Proc Natl Acad Sci U S A 100Suppl 2: 14537-14542.
11. Croset V, Rytz R, Cummins SF, Budd A, Brawand D, et al. (2010) Ancient protostome origin of chemosensory ionotropic glutamate receptors and the evolution of insect taste and olfaction. PLoS Genet 6: e1001064.
12. Silbering AF, Benton R, (2010) Ionotropic and metabotropic mechanisms in chemoreception: 'chance or design'? EMBO Rep 11: 173-179.
13. Hallem EA, Ho MG, Carlson JR, (2004) The molecular basis of odor coding in the Drosophila antenna. Cell 117: 965-979.
14. Yao CA, Ignell R, Carlson JR, (2005) Chemosensory coding by neurons in the coeloconic sensilla of the Drosophila antenna. J Neurosci 25: 8359-8367.
15. Ai M, Min S, Grosjean Y, Leblanc C, Bell R, et al. (2010) Acid sensing by the Drosophila olfactory system. Nature 468: 691-695.
16. Getahun MN, Wicher D, Hansson BS, Olsson SB, (2012) Temporal response dynamics of Drosophila olfactory sensory neurons depends on receptor type and response polarity. Front Cell Neurosci 6: 54.
17. Carde RT, Willis MA, (2008) Navigational strategies used by insects to find distant, wind-borne sources of odor. J Chem Ecol 34: 854-866.
18. Jones WD, Nguyen TA, Kloss B, Lee KJ, Vosshall LB, (2005) Functional conservation of an insect odorant receptor gene across 250 million years of evolution. Curr Biol 15: R119-121.
19. Edwards JS, (1997) The evolution of insect flight: implications for the evolution of the nervous system. Brain Behav Evol 50: 8-12.
20. Wicher D, (2012) Functional and evolutionary aspects of chemoreceptors. Front Cell Neurosci 6: 48.
21. Kain P, Chakraborty TS, Sundaram S, Siddiqi O, Rodrigues V, et al. (2008) Reduced odor responses from antennal neurons of G(q)alpha, phospholipase Cbeta, and rdgA mutants in Drosophila support a role for a phospholipid intermediate in insect olfactory transduction. J Neurosci 28: 4745-4755.
22. Yao CA, Carlson JR, (2010) Role of G-proteins in odor-sensing and CO2-sensing neurons in Drosophila. J Neurosci 30: 4562-4572.
23. Deng Y, Zhang W, Farhat K, Oberland S, Gisselmann G, et al. (2011) The Stimulatory Galpha(s) Protein Is Involved in Olfactory Signal Transduction in Drosophila. PLoS One 6: e18605.
24. Sargsyan V, Getahun MN, Lavista Llanos S, Olsson SB, Hansson BS, et al. (2011) Phosphorylation via PKC regulates the function of the Drosophila odorant coreceptor. Front Cell Neurosci 5: 5.
25. Olsson SB, Getahun MN, Wicher D, Hansson BS, (2011) Piezo-controlled microinjection: An in vivo complement for in vitro sensory studies in insects. J Neurosci Methods 201: 385-389.
26. Dekker T, Ibba I, Siju KP, Stensmyr MC, Hansson BS, (2006) Olfactory shifts parallel superspecialism for toxic fruit in Drosophila melanogaster sibling, D. sechellia. Curr Biol 16: 101-109.
27. Pellegrino M, Nakagawa T, Vosshall LB, (2010) Single sensillum recordings in the insects Drosophila melanogaster and Anopheles gambiae. J Vis Exp 17: 1-5.
28. Kaissling K-E, Thorson J (1980) Insect olfactory sensilla: Structural, chemical and electrical aspects of the functional organization. In: Sattelle DB, Hall LM, Hildebrand JG, editors. Receptors for neurotransmitters, hormones and pheromones in insects. Amsterdam: Elsevier/North-Holland. 261-282.
29. Brand AH, Perrimon N, (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415.
30. Wang JW, Wong AM, Flores J, Vosshall LB, Axel R, (2003) Two-photon calcium imaging reveals an odor-evoked map of activity in the fly brain. Cell 112: 271-282.
31. Larsson MC, Domingos AI, Jones WD, Chiappe ME, Amrein H, et al. (2004) Or83b encodes a broadly expressed odorant receptor essential for Drosophila olfaction. Neuron 43: 703-714.
32. Hallem EA, Carlson JR, (2006) Coding of odors by a receptor repertoire. Cell 125: 143-160.
33. Baumann A, Frings S, Godde M, Seifert R, Kaupp UB, (1994) Primary structure and functional expression of a Drosophila cyclic nucleotide-gated channel present in eyes and antennae. Embo J 13: 5040-5050.
34. Nakagawa T, Vosshall LB, (2009) Controversy and consensus: noncanonical signaling mechanisms in the insect olfactory system. Curr Opin Neurobiol 19: 284-292.
35. Riesgo-Escovar J, Raha D, Carlson JR, (1995) Requirement for a phospholipase C in odor response: overlap between olfaction and vision in Drosophila. Proc Natl Acad Sci U S A 92: 2864-2868.
36. Gomez-Diaz C, Martin F, Alcorta E, (2004) The cAMP transduction cascade mediates olfactory reception in Drosophila melanogaster. Behavior Genetics 34: 395-406.
37. Gomez-Diaz C, Martin F, Alcorta E, (2006) The Inositol 1,4,5-triphosphate kinase1 gene affects olfactory reception in Drosophila melanogaster. Behav Genet 36: 309-321.
38. Chatterjee A, Roman G, Hardin PE, (2009) Go contributes to olfactory reception in Drosophila melanogaster. BMC Physiol 9: 22.
39. Nagel KI, Wilson RI, (2011) Biophysical mechanisms underlying olfactory receptor neuron dynamics. Nat Neurosci 14: 208-216.
40. Nordström KJ, Almen MS, Edstam MM, Fredriksson R, Schioth HB, (2011) Independent HHsearch, Needleman-Wunsch-based and motif analyses reveals the overall hierarchy for most of the G protein-coupled receptor families. Mol Biol Evol 28: 2471-2480.
41. Sato K, Tanaka K, Touhara K, (2011) Sugar-regulated cation channel formed by an insect gustatory receptor. Proc Natl Acad Sci U S A 108: 11680-116805.