-
2
-
-
0014666638
-
Insect olfaction: deciphering system for chemical messages
-
Schneider D. Insect olfaction: deciphering system for chemical messages. Science 163 (1969) 1031-1037
-
(1969)
Science
, vol.163
, pp. 1031-1037
-
-
Schneider, D.1
-
3
-
-
58249111556
-
Fifty years of pheromones
-
Wyatt T.D. Fifty years of pheromones. Nature 457 (2009) 262-263
-
(2009)
Nature
, vol.457
, pp. 262-263
-
-
Wyatt, T.D.1
-
4
-
-
33751118221
-
Comparative chemosensation from receptors to ecology
-
Bargmann C.I. Comparative chemosensation from receptors to ecology. Nature 444 (2006) 295-301
-
(2006)
Nature
, vol.444
, pp. 295-301
-
-
Bargmann, C.I.1
-
5
-
-
0021845642
-
Odorant-sensitive adenylate cyclase may mediate olfactory reception
-
Pace U., Hanski E., Salomon Y., and Lancet D. Odorant-sensitive adenylate cyclase may mediate olfactory reception. Nature 316 (1985) 255-258
-
(1985)
Nature
, vol.316
, pp. 255-258
-
-
Pace, U.1
Hanski, E.2
Salomon, Y.3
Lancet, D.4
-
6
-
-
0023034999
-
The odorant-sensitive adenylate cyclase of olfactory receptor cells. Differential stimulation by distinct classes of odorants
-
Sklar P.B., Anholt R.R., and Snyder S.H. The odorant-sensitive adenylate cyclase of olfactory receptor cells. Differential stimulation by distinct classes of odorants. J Biol Chem 261 (1986) 15538-15543
-
(1986)
J Biol Chem
, vol.261
, pp. 15538-15543
-
-
Sklar, P.B.1
Anholt, R.R.2
Snyder, S.H.3
-
7
-
-
0024475378
-
Golf: an olfactory neuron specific-G protein involved in odorant signal transduction
-
Jones D.T., and Reed R.R. Golf: an olfactory neuron specific-G protein involved in odorant signal transduction. Science 244 (1989) 790-795
-
(1989)
Science
, vol.244
, pp. 790-795
-
-
Jones, D.T.1
Reed, R.R.2
-
8
-
-
0025825726
-
A novel multigene family may encode odorant receptors: a molecular basis for odor recognition
-
Buck L., and Axel R. A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell 65 (1991) 175-187
-
(1991)
Cell
, vol.65
, pp. 175-187
-
-
Buck, L.1
Axel, R.2
-
9
-
-
2942716895
-
The molecular basis of odor coding in the Drosophila antenna
-
Hallem E.A., Ho M.G., and Carlson J.R. The molecular basis of odor coding in the Drosophila antenna. Cell 117 (2004) 965-979
-
(2004)
Cell
, vol.117
, pp. 965-979
-
-
Hallem, E.A.1
Ho, M.G.2
Carlson, J.R.3
-
10
-
-
0025364002
-
Rapid kinetics of second messenger formation in olfactory transduction
-
Breer H., Boekhoff I., and Tareilus E. Rapid kinetics of second messenger formation in olfactory transduction. Nature 345 (1990) 65-68
-
(1990)
Nature
, vol.345
, pp. 65-68
-
-
Breer, H.1
Boekhoff, I.2
Tareilus, E.3
-
11
-
-
0025374734
-
Pheromone-induced stimulation of inositol trisphosphate formation in insect antennae is mediated by G-proteins
-
Boekhoff I., Raming K., and Breer H. Pheromone-induced stimulation of inositol trisphosphate formation in insect antennae is mediated by G-proteins. J Comp Physiol [B] 160 (1990) 99
-
(1990)
J Comp Physiol [B]
, vol.160
, pp. 99
-
-
Boekhoff, I.1
Raming, K.2
Breer, H.3
-
12
-
-
0025409031
-
Cyclic GMP levels and guanylate cyclase activity in pheromone-sensitive antennae of the silkmoths Antheraea polyphemus and Bombyx mori
-
Ziegelberger G., van den Berg M.J., Kaissling K.E., Klumpp S., and Schultz J.E. Cyclic GMP levels and guanylate cyclase activity in pheromone-sensitive antennae of the silkmoths Antheraea polyphemus and Bombyx mori. J Neurosci 10 (1990) 1217-1225
-
(1990)
J Neurosci
, vol.10
, pp. 1217-1225
-
-
Ziegelberger, G.1
van den Berg, M.J.2
Kaissling, K.E.3
Klumpp, S.4
Schultz, J.E.5
-
13
-
-
0026076194
-
Dual activation of a sex pheromone-dependent ion channel from insect olfactory dendrites by protein kinase C activators and cyclic GMP
-
Zufall F., and Hatt H. Dual activation of a sex pheromone-dependent ion channel from insect olfactory dendrites by protein kinase C activators and cyclic GMP. Proc Natl Acad Sci U S A 88 (1991) 8520-8524
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 8520-8524
-
-
Zufall, F.1
Hatt, H.2
-
14
-
-
0028371267
-
Inositol-trisphosphate-dependent calcium currents precede cation currents in insect olfactory receptor neurons in vitro
-
Stengl M. Inositol-trisphosphate-dependent calcium currents precede cation currents in insect olfactory receptor neurons in vitro. J Comp Physiol [A] 174 (1994) 187-194
-
(1994)
J Comp Physiol [A]
, vol.174
, pp. 187-194
-
-
Stengl, M.1
-
15
-
-
0029584040
-
Identification of a Drosophila G protein alpha subunit (dGq alpha-3) expressed in chemosensory cells and central neurons
-
Talluri S., Bhatt A., and Smith D.P. Identification of a Drosophila G protein alpha subunit (dGq alpha-3) expressed in chemosensory cells and central neurons. Proc Natl Acad Sci U S A 92 (1995) 11475-11479
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 11475-11479
-
-
Talluri, S.1
Bhatt, A.2
Smith, D.P.3
-
16
-
-
0031003894
-
G-protein activation, identification and immunolocalization in pheromone-sensitive sensilla trichodea of moths
-
Laue M., Maida R., and Redkozubov A. G-protein activation, identification and immunolocalization in pheromone-sensitive sensilla trichodea of moths. Cell Tissue Res 288 (1997) 149-158
-
(1997)
Cell Tissue Res
, vol.288
, pp. 149-158
-
-
Laue, M.1
Maida, R.2
Redkozubov, A.3
-
17
-
-
16844374523
-
Expression and localization of three G protein alpha subunits, G(o), G(q), and G(s), in adult antennae of the silkmoth (Bombyx mori)
-
Miura N., Atsumi S., Tabunoki H., and Sato R. Expression and localization of three G protein alpha subunits, G(o), G(q), and G(s), in adult antennae of the silkmoth (Bombyx mori). J Comp Neurol 485 (2005) 143-152
-
(2005)
J Comp Neurol
, vol.485
, pp. 143-152
-
-
Miura, N.1
Atsumi, S.2
Tabunoki, H.3
Sato, R.4
-
18
-
-
0036237519
-
Expression pattern in the antennae of a newly isolated lepidopteran Gq protein alpha subunit cDNA
-
Jacquin-Joly E., Francois M.C., Burnet M., Lucas P., Bourrat F., and Maida R. Expression pattern in the antennae of a newly isolated lepidopteran Gq protein alpha subunit cDNA. Eur J Biochem 269 (2002) 2133-2142
-
(2002)
Eur J Biochem
, vol.269
, pp. 2133-2142
-
-
Jacquin-Joly, E.1
Francois, M.C.2
Burnet, M.3
Lucas, P.4
Bourrat, F.5
Maida, R.6
-
19
-
-
44649094691
-
qα, phospholipase Cβ, and rdgA mutants in Drosophila support a role for a phospholipid intermediate in insect olfactory transduction
-
αq protein and a phospholipid second messenger cascade.
-
αq protein and a phospholipid second messenger cascade.
-
(2008)
J Neurosci
, vol.28
, pp. 4745-4755
-
-
Kain, P.1
Chakraborty, T.S.2
Sundaram, S.3
Siddiqi, O.4
Rodrigues, V.5
Hasan, G.6
-
20
-
-
33750220493
-
Gα encoding gene family of the malaria vector mosquito Anopheles gambiae: expression analysis and immunolocalization of AGαq and AGαo in female antennae
-
Rutzler M., Lu T., and Zwiebel L.J. Gα encoding gene family of the malaria vector mosquito Anopheles gambiae: expression analysis and immunolocalization of AGαq and AGαo in female antennae. J Comp Neurol 499 (2006) 533-545
-
(2006)
J Comp Neurol
, vol.499
, pp. 533-545
-
-
Rutzler, M.1
Lu, T.2
Zwiebel, L.J.3
-
21
-
-
0027994863
-
Primary structure and functional expression of a Drosophila cyclic nucleotide-gated channel present in eyes and antennae
-
Baumann A., Frings S., Godde M., Seifert R., and Kaupp U.B. Primary structure and functional expression of a Drosophila cyclic nucleotide-gated channel present in eyes and antennae. EMBO J 13 (1994) 5040-5050
-
(1994)
EMBO J
, vol.13
, pp. 5040-5050
-
-
Baumann, A.1
Frings, S.2
Godde, M.3
Seifert, R.4
Kaupp, U.B.5
-
22
-
-
0032146259
-
+ channel gene ether a go-go is required for the transduction of a subset of odorants in adult Drosophila melanogaster
-
+ channel gene ether a go-go is required for the transduction of a subset of odorants in adult Drosophila melanogaster. J Neurosci 18 (1998) 5603-5613
-
(1998)
J Neurosci
, vol.18
, pp. 5603-5613
-
-
Dubin, A.E.1
Liles, M.M.2
Harris, G.L.3
-
23
-
-
0028639915
-
Olfactory physiology in the Drosophila maxillary palp requires the visual system gene rdgB
-
Riesgo-Escovar J.R., Woodard C., and Carlson J.R. Olfactory physiology in the Drosophila maxillary palp requires the visual system gene rdgB. J Comp Physiol [A] 175 (1994) 687-693
-
(1994)
J Comp Physiol [A]
, vol.175
, pp. 687-693
-
-
Riesgo-Escovar, J.R.1
Woodard, C.2
Carlson, J.R.3
-
24
-
-
0028987239
-
Requirement for a phospholipase C in odor response: overlap between olfaction and vision in Drosophila
-
Riesgo-Escovar J., Raha D., and Carlson J.R. Requirement for a phospholipase C in odor response: overlap between olfaction and vision in Drosophila. Proc Natl Acad Sci U S A 92 (1995) 2864-2868
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 2864-2868
-
-
Riesgo-Escovar, J.1
Raha, D.2
Carlson, J.R.3
-
25
-
-
0034904858
-
Mutations affecting the cAMP transduction pathway modify olfaction in Drosophila
-
Martin F., Charro M.J., and Alcorta E. Mutations affecting the cAMP transduction pathway modify olfaction in Drosophila. J Comp Physiol [A] 187 (2001) 359-370
-
(2001)
J Comp Physiol [A]
, vol.187
, pp. 359-370
-
-
Martin, F.1
Charro, M.J.2
Alcorta, E.3
-
26
-
-
33646344771
-
The inositol 1,4,5-triphosphate kinase1 gene affects olfactory reception in Drosophila melanogaster
-
Gomez-Diaz C., Martin F., and Alcorta E. The inositol 1,4,5-triphosphate kinase1 gene affects olfactory reception in Drosophila melanogaster. Behav Genet 36 (2006) 309-321
-
(2006)
Behav Genet
, vol.36
, pp. 309-321
-
-
Gomez-Diaz, C.1
Martin, F.2
Alcorta, E.3
-
27
-
-
3142697263
-
The cAMP transduction cascade mediates olfactory reception in Drosophila melanogaster
-
Gomez-Diaz C., Martin F., and Alcorta E. The cAMP transduction cascade mediates olfactory reception in Drosophila melanogaster. Behav Genet 34 (2004) 395-406
-
(2004)
Behav Genet
, vol.34
, pp. 395-406
-
-
Gomez-Diaz, C.1
Martin, F.2
Alcorta, E.3
-
28
-
-
0037122913
-
Novel genomic cDNA hybrids produce effective RNA interference in adult Drosophila
-
Kalidas S., and Smith D.P. Novel genomic cDNA hybrids produce effective RNA interference in adult Drosophila. Neuron 33 (2002) 177-184
-
(2002)
Neuron
, vol.33
, pp. 177-184
-
-
Kalidas, S.1
Smith, D.P.2
-
29
-
-
0033525896
-
A spatial map of olfactory receptor expression in the Drosophila antenna
-
Vosshall L.B., Amrein H., Morozov P.S., Rzhetsky A., and Axel R. A spatial map of olfactory receptor expression in the Drosophila antenna. Cell 96 (1999) 725-736
-
(1999)
Cell
, vol.96
, pp. 725-736
-
-
Vosshall, L.B.1
Amrein, H.2
Morozov, P.S.3
Rzhetsky, A.4
Axel, R.5
-
30
-
-
0033082410
-
A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila
-
Clyne P.J., Warr C.G., Freeman M.R., Lessing D., Kim J., and Carlson J.R. A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila. Neuron 22 (1999) 327-338
-
(1999)
Neuron
, vol.22
, pp. 327-338
-
-
Clyne, P.J.1
Warr, C.G.2
Freeman, M.R.3
Lessing, D.4
Kim, J.5
Carlson, J.R.6
-
31
-
-
0344200118
-
Identification of candidate Drosophila olfactory receptors from genomic DNA sequence
-
Gao Q., and Chess A. Identification of candidate Drosophila olfactory receptors from genomic DNA sequence. Genomics 60 (1999) 31-39
-
(1999)
Genomics
, vol.60
, pp. 31-39
-
-
Gao, Q.1
Chess, A.2
-
32
-
-
0035979235
-
Functional analysis of an olfactory receptor in Drosophila melanogaster
-
Stortkuhl K.F., and Kettler R. Functional analysis of an olfactory receptor in Drosophila melanogaster. Proc Natl Acad Sci U S A 98 (2001) 9381-9385
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 9381-9385
-
-
Stortkuhl, K.F.1
Kettler, R.2
-
33
-
-
33645996346
-
Coding of odors by a receptor repertoire
-
Hallem E.A., and Carlson J.R. Coding of odors by a receptor repertoire. Cell 125 (2006) 143-160
-
(2006)
Cell
, vol.125
, pp. 143-160
-
-
Hallem, E.A.1
Carlson, J.R.2
-
34
-
-
33244480581
-
Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo
-
This paper was the first to question the dogma that insect ORs are GPCRs. Experiments herein define insect ORs and OR83b as a novel transmembrane family with a distinct topology from conventional GPCRs. Moreover, OR83b is shown to be essential and sufficient to maintain the OR/OR83b complex on the membrane of the olfactory neurons.
-
Benton R., Sachse S., Michnick S.W., and Vosshall L.B. Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo. PLoS Biol 4 (2006) e20. This paper was the first to question the dogma that insect ORs are GPCRs. Experiments herein define insect ORs and OR83b as a novel transmembrane family with a distinct topology from conventional GPCRs. Moreover, OR83b is shown to be essential and sufficient to maintain the OR/OR83b complex on the membrane of the olfactory neurons.
-
(2006)
PLoS Biol
, vol.4
-
-
Benton, R.1
Sachse, S.2
Michnick, S.W.3
Vosshall, L.B.4
-
35
-
-
33644509247
-
A general model of G protein-coupled receptor sequences and its application to detect remote homologs
-
This paper describes a novel structural search algorithm to identify GPCRs and concludes based on bioinformatic evidence that insect ORs are distinct from GPCRs.
-
Wistrand M., Kall L., and Sonnhammer E.L. A general model of G protein-coupled receptor sequences and its application to detect remote homologs. Protein Sci 15 (2006) 509-521. This paper describes a novel structural search algorithm to identify GPCRs and concludes based on bioinformatic evidence that insect ORs are distinct from GPCRs.
-
(2006)
Protein Sci
, vol.15
, pp. 509-521
-
-
Wistrand, M.1
Kall, L.2
Sonnhammer, E.L.3
-
36
-
-
36549057678
-
Membrane topology of the Drosophila OR83b odorant receptor
-
••], most importantly confirming the inferred extracellular disposition of the C-terminus.
-
••], most importantly confirming the inferred extracellular disposition of the C-terminus.
-
(2007)
FEBS Lett
, vol.581
, pp. 5601-5604
-
-
Lundin, C.1
Käll, L.2
Kreher, K.A.3
Kapp, K.4
Sonnhammer, E.L.5
Carlson, J.R.6
von Heijne, G.7
Nilsson, I.8
-
37
-
-
46849094135
-
Drosophila odorant receptors are novel seven transmembrane domain proteins that can signal independently of heterotrimeric G proteins
-
In this paper, the authors used pharmacological inhibitors of several G-protein-mediated pathways to investigate the signaling mechanism of insect ORs, and found that odorant-evoked responses were independent of conventional G-protein-coupled second messenger pathways. They also carry out careful analysis of the topology of OR22a, confirming for a single OR the conclusions reached for the OR83b co-receptor.
-
Smart R., Kiely A., Beale M., Vargas E., Carraher C., Kralicek A.V., Christie D.L., Chen C., Newcomb R.D., and Warr C.G. Drosophila odorant receptors are novel seven transmembrane domain proteins that can signal independently of heterotrimeric G proteins. Insect Biochem Mol Biol 38 (2008) 770-780. In this paper, the authors used pharmacological inhibitors of several G-protein-mediated pathways to investigate the signaling mechanism of insect ORs, and found that odorant-evoked responses were independent of conventional G-protein-coupled second messenger pathways. They also carry out careful analysis of the topology of OR22a, confirming for a single OR the conclusions reached for the OR83b co-receptor.
-
(2008)
Insect Biochem Mol Biol
, vol.38
, pp. 770-780
-
-
Smart, R.1
Kiely, A.2
Beale, M.3
Vargas, E.4
Carraher, C.5
Kralicek, A.V.6
Christie, D.L.7
Chen, C.8
Newcomb, R.D.9
Warr, C.G.10
-
38
-
-
0042475560
-
A candidate olfactory receptor subtype highly conserved across different insect orders
-
Krieger J., Klink O., Mohl C., Raming K., and Breer H. A candidate olfactory receptor subtype highly conserved across different insect orders. J Comp Physiol A 189 (2003) 519-526
-
(2003)
J Comp Physiol A
, vol.189
, pp. 519-526
-
-
Krieger, J.1
Klink, O.2
Mohl, C.3
Raming, K.4
Breer, H.5
-
39
-
-
1842737518
-
A highly conserved candidate chemoreceptor expressed in both olfactory and gustatory tissues in the malaria vector Anopheles gambiae
-
Pitts R.J., Fox A.N., and Zwiebel L.J. A highly conserved candidate chemoreceptor expressed in both olfactory and gustatory tissues in the malaria vector Anopheles gambiae. Proc Natl Acad Sci U S A 101 (2004) 5058-5063
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 5058-5063
-
-
Pitts, R.J.1
Fox, A.N.2
Zwiebel, L.J.3
-
40
-
-
13944276751
-
Functional conservation of an insect odorant receptor gene across 250 million years of evolution
-
Jones W.D., Nguyen T.A., Kloss B., Lee K.J., and Vosshall L.B. Functional conservation of an insect odorant receptor gene across 250 million years of evolution. Curr Biol 15 (2005) R119-R121
-
(2005)
Curr Biol
, vol.15
-
-
Jones, W.D.1
Nguyen, T.A.2
Kloss, B.3
Lee, K.J.4
Vosshall, L.B.5
-
41
-
-
4444222660
-
Or83b encodes a broadly expressed odorant receptor essential for Drosophila olfaction
-
Larsson M.C., Domingos A.I., Jones W.D., Chiappe M.E., Amrein H., and Vosshall L.B. Or83b encodes a broadly expressed odorant receptor essential for Drosophila olfaction. Neuron 43 (2004) 703-714
-
(2004)
Neuron
, vol.43
, pp. 703-714
-
-
Larsson, M.C.1
Domingos, A.I.2
Jones, W.D.3
Chiappe, M.E.4
Amrein, H.5
Vosshall, L.B.6
-
42
-
-
14844361202
-
Odorant receptor heterodimerization in the olfactory system of Drosophila melanogaster
-
Neuhaus E.M., Gisselmann G., Zhang W., Dooley R., Stortkuhl K., and Hatt H. Odorant receptor heterodimerization in the olfactory system of Drosophila melanogaster. Nat Neurosci 8 (2005) 15-17
-
(2005)
Nat Neurosci
, vol.8
, pp. 15-17
-
-
Neuhaus, E.M.1
Gisselmann, G.2
Zhang, W.3
Dooley, R.4
Stortkuhl, K.5
Hatt, H.6
-
43
-
-
14844351843
-
Insect sex-pheromone signals mediated by specific combinations of olfactory receptors
-
Nakagawa T., Sakurai T., Nishioka T., and Touhara K. Insect sex-pheromone signals mediated by specific combinations of olfactory receptors. Science 307 (2005) 1638-1642
-
(2005)
Science
, vol.307
, pp. 1638-1642
-
-
Nakagawa, T.1
Sakurai, T.2
Nishioka, T.3
Touhara, K.4
-
44
-
-
36048952387
-
An essential role for a CD36-related receptor in pheromone detection in Drosophila
-
This paper shows the first functional evidence that Drosophila CD36 homolog, SNMP, is required for the detection of cVA, male-specific fatty-acid-derived pheromone. Functional expression of a moth pheromone receptor in Drosophila also requires SNMP. This result provides new insight into the molecular basis of pheromone detection in insects.
-
Benton R., Vannice K.S., and Vosshall L.B. An essential role for a CD36-related receptor in pheromone detection in Drosophila. Nature 450 (2007) 289-293. This paper shows the first functional evidence that Drosophila CD36 homolog, SNMP, is required for the detection of cVA, male-specific fatty-acid-derived pheromone. Functional expression of a moth pheromone receptor in Drosophila also requires SNMP. This result provides new insight into the molecular basis of pheromone detection in insects.
-
(2007)
Nature
, vol.450
, pp. 289-293
-
-
Benton, R.1
Vannice, K.S.2
Vosshall, L.B.3
-
45
-
-
49449092859
-
SNMP is a signaling component required for pheromone sensitivity in Drosophila
-
Using a forward genetic screen for cVA-insensitive mutants, the authors demonstrate that SNMP is required for the detection of cVA.
-
Jin X., Ha T.S., and Smith D.P. SNMP is a signaling component required for pheromone sensitivity in Drosophila. Proc Natl Acad Sci U S A 105 (2008) 10996-11001. Using a forward genetic screen for cVA-insensitive mutants, the authors demonstrate that SNMP is required for the detection of cVA.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 10996-11001
-
-
Jin, X.1
Ha, T.S.2
Smith, D.P.3
-
46
-
-
58149099623
-
Variant ionotropic glutamate receptors as chemosensory receptors in Drosophila
-
The authors identified a novel class of candidate chemosensory receptors, iGluR-related genes (IRs) in Drosophila using a bioinformatic screen for olfactory-enriched genes. Detailed functional and expression analysis of this new family provides evidence that the IRs function as odorant receptors in coeloconic sensilla.
-
Benton R., Vannice K.S., Gomez-Diaz C., and Vosshall L.B. Variant ionotropic glutamate receptors as chemosensory receptors in Drosophila. Cell 136 (2009) 149-162. The authors identified a novel class of candidate chemosensory receptors, iGluR-related genes (IRs) in Drosophila using a bioinformatic screen for olfactory-enriched genes. Detailed functional and expression analysis of this new family provides evidence that the IRs function as odorant receptors in coeloconic sensilla.
-
(2009)
Cell
, vol.136
, pp. 149-162
-
-
Benton, R.1
Vannice, K.S.2
Gomez-Diaz, C.3
Vosshall, L.B.4
-
47
-
-
0035979264
-
Functional expression and characterization of a Drosophila odorant receptor in a heterologous cell system
-
Wetzel C.H., Behrendt H.-J., Gisselmann G., Störtkuhl K.F., Hovemann B., and Hatt H. Functional expression and characterization of a Drosophila odorant receptor in a heterologous cell system. Proc Natl Acad Sci U S A 98 (2001) 9377-9380
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 9377-9380
-
-
Wetzel, C.H.1
Behrendt, H.-J.2
Gisselmann, G.3
Störtkuhl, K.F.4
Hovemann, B.5
Hatt, H.6
-
48
-
-
9344223948
-
Identification and functional characterization of a sex pheromone receptor in the silkmoth Bombyx mori
-
Sakurai T., Nakagawa T., Mitsuno H., Mori H., Endo Y., Tanoue S., Yasukochi Y., Touhara K., and Nishioka T. Identification and functional characterization of a sex pheromone receptor in the silkmoth Bombyx mori. Proc Natl Acad Sci U S A 101 (2004) 16653-16658
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 16653-16658
-
-
Sakurai, T.1
Nakagawa, T.2
Mitsuno, H.3
Mori, H.4
Endo, Y.5
Tanoue, S.6
Yasukochi, Y.7
Touhara, K.8
Nishioka, T.9
-
49
-
-
18844406464
-
Candidate pheromone receptors of the silkmoth Bombyx mori
-
Krieger J., Grosse-Wilde E., Gohl T., and Breer H. Candidate pheromone receptors of the silkmoth Bombyx mori. Eur J Neurosci 21 (2005) 2167-2176
-
(2005)
Eur J Neurosci
, vol.21
, pp. 2167-2176
-
-
Krieger, J.1
Grosse-Wilde, E.2
Gohl, T.3
Breer, H.4
-
50
-
-
33845432774
-
Functional analysis of a Drosophila melanogaster olfactory receptor expressed in Sf9 cells
-
Kiely A., Authier A., Kralicek A.V., Warr C.G., and Newcomb R.D. Functional analysis of a Drosophila melanogaster olfactory receptor expressed in Sf9 cells. J Neurosci Methods 159 (2007) 189-194
-
(2007)
J Neurosci Methods
, vol.159
, pp. 189-194
-
-
Kiely, A.1
Authier, A.2
Kralicek, A.V.3
Warr, C.G.4
Newcomb, R.D.5
-
51
-
-
42549164169
-
Insect olfactory receptors are heteromeric ligand-gated ion channels
-
On the basis of electrophysiological and biochemical analysis on the insect ORs expressed in various heterologous expression systems, the authors reveal that the insect OR/OR83b complex itself produces odorant-evoked cation channel activity, independent of G-protein signaling.
-
Sato K., Pellegrino M., Nakagawa T., Nakagawa T., Vosshall L.B., and Touhara K. Insect olfactory receptors are heteromeric ligand-gated ion channels. Nature 452 (2008) 1002-1006. On the basis of electrophysiological and biochemical analysis on the insect ORs expressed in various heterologous expression systems, the authors reveal that the insect OR/OR83b complex itself produces odorant-evoked cation channel activity, independent of G-protein signaling.
-
(2008)
Nature
, vol.452
, pp. 1002-1006
-
-
Sato, K.1
Pellegrino, M.2
Nakagawa, T.3
Nakagawa, T.4
Vosshall, L.B.5
Touhara, K.6
-
52
-
-
42549118499
-
Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels
-
By electrophysiological recordings, the authors show that G-protein-mediated cAMP is generated in response to odorants. Moreover, they also reveal that OR83b alone functions as a cyclic nucleotide gated channel.
-
Wicher D., Schafer R., Bauernfeind R., Stensmyr M.C., Heller R., Heinemann S.H., and Hansson B.S. Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels. Nature 452 (2008) 1007-1011. By electrophysiological recordings, the authors show that G-protein-mediated cAMP is generated in response to odorants. Moreover, they also reveal that OR83b alone functions as a cyclic nucleotide gated channel.
-
(2008)
Nature
, vol.452
, pp. 1007-1011
-
-
Wicher, D.1
Schafer, R.2
Bauernfeind, R.3
Stensmyr, M.C.4
Heller, R.5
Heinemann, S.H.6
Hansson, B.S.7
-
53
-
-
84890873409
-
Drosophila photoreceptors and signaling mechanisms
-
Katz B., and Minke B. Drosophila photoreceptors and signaling mechanisms. Front Cell Neurosci 3 (2009) 1-17
-
(2009)
Front Cell Neurosci
, vol.3
, pp. 1-17
-
-
Katz, B.1
Minke, B.2
-
54
-
-
0041878279
-
Lessons from peppers and peppermint: the molecular logic of thermosensation
-
Jordt S.E., McKemy D.D., and Julius D. Lessons from peppers and peppermint: the molecular logic of thermosensation. Curr Opin Neurobiol 13 (2003) 487-492
-
(2003)
Curr Opin Neurobiol
, vol.13
, pp. 487-492
-
-
Jordt, S.E.1
McKemy, D.D.2
Julius, D.3
-
55
-
-
45449113774
-
Activation of pheromone-sensitive neurons is mediated by conformational activation of pheromone-binding protein
-
Structural analysis of LUSH protein shows that a dominant negative LUSH mutant can activate pheromone-sensitive neurons in the absence of cVA by mimicking the conformational change of LUSH normally induced by pheromone. This result suggests that odorant-binding and pheromone-binding proteins seem to be more than simple carriers, and might play an important role in odor transduction in insects.
-
Laughlin J.D., Ha T.S., Jones D.N., and Smith D.P. Activation of pheromone-sensitive neurons is mediated by conformational activation of pheromone-binding protein. Cell 133 (2008) 1255-1265. Structural analysis of LUSH protein shows that a dominant negative LUSH mutant can activate pheromone-sensitive neurons in the absence of cVA by mimicking the conformational change of LUSH normally induced by pheromone. This result suggests that odorant-binding and pheromone-binding proteins seem to be more than simple carriers, and might play an important role in odor transduction in insects.
-
(2008)
Cell
, vol.133
, pp. 1255-1265
-
-
Laughlin, J.D.1
Ha, T.S.2
Jones, D.N.3
Smith, D.P.4
|