DNA damage activates a complex transcriptional response in murine lymphocytes that includes both physiological and cancer-predisposition programs

BMC Genomics

Volumn 14, Issue 1, 2013, Pages

  Innes, Cynthia L ^a   Hesse, Jill E ^a   Palii, Stela S ^a   Helmink, Beth A ^b   Holub, Abigail J ^b   Sleckman, Barry P ^b   Paules, Richard S ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

B cells; DNA damage; Double strand breaks; Ionizing radiation; miR 155; Transcriptome profiles

Indexed keywords

K RAS PROTEIN; MICRORNA 155; SUPPRESSOR OF CYTOKINE SIGNALING 1; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CANCER SUSCEPTIBILITY; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; GENE EXPRESSION; GENE SEQUENCE; GENOTOXICITY; IONIZING RADIATION; KRAS GENE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; PHENOTYPE; PHYSIOLOGY; SOCS1 GENE;

ANIMALS; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; ENDONUCLEASES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LYMPHOCYTES; MICE; MICRORNAS; NEOPLASMS; PROTO-ONCOGENE PROTEINS P21(RAS); SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANSCRIPTION, GENETIC;

MURINAE;

EID: 84874811269     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-14-163     Document Type: Article

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